Basic Information

Insect: Drosophila planitibia
Gene Symbol: Scrt1
Assembly: GCA_035043785.1
Location: JAWNMS010000023.1:5292488-5293889[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 5.7e-05 0.0036 17.6 0.2 1 18 121 138 121 143 0.92

2 5 0.00096 0.059 13.7 0.4 3 23 154 174 153 174 0.98

3 5 1.5e-06 9.1e-05 22.6 5.0 1 23 178 200 178 200 0.97

4 5 3.2e-09 2e-07 31.0 0.5 1 23 206 228 206 228 0.99

5 5 0.00074 0.046 14.1 0.5 1 20 234 253 234 255 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	5.7e-05	0.0036	17.6	0.2	1	18	121	138	121	143	0.92
2	5	0.00096	0.059	13.7	0.4	3	23	154	174	153	174	0.98
3	5	1.5e-06	9.1e-05	22.6	5.0	1	23	178	200	178	200	0.97
4	5	3.2e-09	2e-07	31.0	0.5	1	23	206	228	206	228	0.99
5	5	0.00074	0.046	14.1	0.5	1	20	234	253	234	255	0.93

Sequence Information

Coding Sequence: ATGACGAAGGATCAGCAGGTGACGCCCATACCCGAGGAGCTGTACAATCTCAACCAGCTGGCGAATGTGACACTGGCGGCAGGACCGCTTACCACACCAGCCAAGTCTAGTCCCATTTctgccaacaataataacaacagcaacagcaacaacatgttCTATGCCTCATCGGATGATGATTCCACTTACAACTCGTACAGCCACAAGGTGTTCGATCGCAGGAAACTGCGTCGCTGCACCATTTCCGACTCCAATTCCTGtgccagcagcaccaccagcaacagcagcagcagtcgccacTCCAGCGAGCAATCACCTCATGCCCAGGACAACAGTAGCCTAACAATGCTGGACGATGAGCACATTTGTCCCGAGTGCGGCAAGAAGTATTCCACCTCCTCAAATCTGGCGCGCCCTAGACAAACCCACAGGTCAATTATGGACAAGAAGGCGCGTCACTGTCCGTATTGTGAGAAGGTGTACGTCTCGATGCCAGCATTCTCGATGCATGTCCGGACGCACAACCAGGGCTGCAAGTGCAAGACCTGTGGCAAGTGCTTCTCGCGTCCCTGGCTGCTCCAGGGACATCTACGCACCCATACCGGCGAGAAACCTTTCAAGTGCAACGTCTGCAACAAAGCCTTCGCCGACAAGTCCAATCTTCGTGCCCACATTCAGACGCACTCGAACACGAAGCCGCACACGTGTGCCCGCTGTGGCAAGGCCTTTGCCCTCAAGTCGTATCTGTACAAGCACGAGGAGTCCTCATGCATGAAGAATCGCAACAACGAGACAGCaacagtgcagcagcagcagcagcaacccgAACTGAAAGCAacgactgcaacaacaacagcaacaacaacgccatcAGCTGGTCAATCCTTGCCAGATTCGGCCAAGTCAACGCTGGCGCACAAGTTGCTGCAGAAGGAGAAGGATCGCAGGCAGGCGCAGGCTGTAGCTCAAGCTCAGGCACAGGCTGCTCTGGCTTATGGCTATCCTGGACATGGTGGACATGCATCCCGACTAGGCAATCTGGAACATTATGATAGCTACAAGCGCAATGGCATTGTTCAGCCCACTGTGCTGCAGCATCCCAGTGCACTGTATCAGGAGCATATGCTGCCACTagcgctgccactgccactgcccctgccCATGGCCtatccgcagcagcagcagcaacagcaggatcAAGAGCAACCCGTGGACTTTTCGCCCAAGAACAATTTTACGCACTCGGCCAAGACGAGTCCGTTCGAGCTAACTGGCAATTATGCAACAATGGTCGCCTAG
Protein Sequence: MTKDQQVTPIPEELYNLNQLANVTLAAGPLTTPAKSSPISANNNNNSNSNNMFYASSDDDSTYNSYSHKVFDRRKLRRCTISDSNSCASSTTSNSSSSRHSSEQSPHAQDNSSLTMLDDEHICPECGKKYSTSSNLARPRQTHRSIMDKKARHCPYCEKVYVSMPAFSMHVRTHNQGCKCKTCGKCFSRPWLLQGHLRTHTGEKPFKCNVCNKAFADKSNLRAHIQTHSNTKPHTCARCGKAFALKSYLYKHEESSCMKNRNNETATVQQQQQQPELKATTATTTATTTPSAGQSLPDSAKSTLAHKLLQKEKDRRQAQAVAQAQAQAALAYGYPGHGGHASRLGNLEHYDSYKRNGIVQPTVLQHPSALYQEHMLPLALPLPLPLPMAYPQQQQQQQDQEQPVDFSPKNNFTHSAKTSPFELTGNYATMVA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00570584;
90% Identity: iTF_00564843;
80% Identity: -