Basic Information

Insect: Drosophila picticornis
Gene Symbol: Bcl11b
Assembly: GCA_035043845.1
Location: JAWNMR010000492.1:7181098-7199379[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.027 1.7 9.2 2.4 1 23 311 334 311 334 0.95

2 6 7.5e-07 4.6e-05 23.5 1.5 1 23 777 799 777 799 0.99

3 6 0.012 0.77 10.2 4.7 1 23 805 827 805 827 0.99

4 6 1.2e-06 7.2e-05 22.9 3.2 2 23 1104 1125 1103 1125 0.97

5 6 1.5e-05 0.00094 19.4 3.3 1 23 1131 1153 1131 1153 0.99

6 6 2.8e-05 0.0017 18.6 0.4 1 22 1161 1182 1161 1182 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.027	1.7	9.2	2.4	1	23	311	334	311	334	0.95
2	6	7.5e-07	4.6e-05	23.5	1.5	1	23	777	799	777	799	0.99
3	6	0.012	0.77	10.2	4.7	1	23	805	827	805	827	0.99
4	6	1.2e-06	7.2e-05	22.9	3.2	2	23	1104	1125	1103	1125	0.97
5	6	1.5e-05	0.00094	19.4	3.3	1	23	1131	1153	1131	1153	0.99
6	6	2.8e-05	0.0017	18.6	0.4	1	22	1161	1182	1161	1182	0.97

Sequence Information

Coding Sequence: atgtacaacaaaatgCTGTCGATCAGTGAGGATCATGGATTCCGTTCGCTGAGCCATTCCGACTCGACAGAGAACGATGCGGTTGCCGCGCAGGACATCCTCACGTGTGGCGCCTGCCAGAAGACCTTCGCACTGTCGGACATTGTCCGCTTCATTCAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGTCAGTGTACCACACAGGCGCCCAGCATGGATCGCGATGCCGACGAGGGTCGACCCCTGAGTCTGGTCAATCGCCGTCCCTCAATTTCGGCGCCAATCACAGGCCGTAAATCAGCGCCAGTTGCTGGCAGTGGCGCCACAGTTGCTGCCAATGCAATTGCCAGTgcggctgctgccactgcggccgctgcggcggcggcgacagCAGCGGCTGCCGCAGCCGCTGTTGCAAGCAGCGCTGCAAGTGGctcacgcatacacacaccgCCGCCGAGTCCAGCGGATCTGCTCGCCGATGGCGCCAGCAGCACTCCCAAGCGCCTCGTCGATGAGAACGACAATACGACGCCCAAGGCGGACAGCGATGCGCTGACCACCGCCACCGGCGCAGCGGGACTGGAGTCGAGCATCGCTCACAGTCCTCGCGCTCAGTTGGCGCAGGGACAACTGATTGGTCGCGAGGAGTGTGCTCTGCACGATGACAAGCCAAAGGTCAAGCAGGAGCCCTATGCCGATGACGAGCAGCTCGACGAGGAagtggagctggagcaggcTCCagaacaagagcagcaacaggagcggGATAgagagcaggagcaggagcgggAAAGGGAACTGAATGCGCAACTGCTGACACAGGCGACTGACAGAGACGAGTGCCAACAGCCGCTGGCCAAGCGGCCCAAAATGGAGCTCGTCGATGCCGAAGCGAATACGGTGCACACAGAACCCAGCAATTACACATGTTCGACGTGCAAGACCCGCTACACATCCGCGTGGCGCCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTGGAGACGGGTGGCTGTGGCGCCACCTTGACTGTGGCCACACCCGCCGCTCTCAAtgcggcggcaacagcagcagcagcacaagccaccagcgtcagcgtcagtcCAAATCGTAGTCTCAGTcccgcagcagcaactgttggtAGCGTCtctctgccgctgccgctgcacGCGCTCATGGCGCAGTCTCCAGCGCcaaagcgcagcagcagcaacagcagcgccgccgccgcagcggcagcagcagcagcagccgcaattTCTGCAGGCTCGGCCAAtacgagcagcaacagcagcagtaatgtgagcagcagtagcaacagcgcCAACTCACCCacacagcaactgttgcagcagcgtgtacaacagcaacagcagcagcagcagcagcaacaacaacaacagcagcagcagcagcaacagcagcagcaacagagtcTAGCGCTGGCAGCAGGCATGCGTCATCATGCGCTTCTGGCGCCACCAGATTCGTTGCACGCGAACCCCTTCCAGCTGCTGCGCATGCCACTGCCACCCGCGCTGTCGCAGAGCAATGTAGTTCCTAGCGTGTCGCCGCTGTTTGGCCGCCCCACGCCCGCCGATCACTATCGCATGGAGCAGCTGGTTAGCGAGCAGTTCCGGCACCATGGCTTCAGTCtggccgctgccgctgccgccgcccaGGCGCAATTCAATGCCAatacacagcagcagcaacaacagcagcagcagcagcaacctgCTCAGCCCATTGCTGTCAATGTTCCTAATCCCGTCGAGCAGCGACCGCCATCGAGCAATAGCAGCCAGCGTGGCTCAGTACCGCCCGCTGCACTACCGCCTCCGTCGCTCAgctcacagcagcaacagcagcaacaacaacagcaacagcagcagcagcagcaacagcaacaacaacagcagcaacaacagcaacagcaacaacagcagcatcaacaagtGGCCGCagcggccgctgctgctgcagctgcactgAGTCCAGCTGCTAGTTTAAACTTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAACAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCTGCCTCCCTTTCGGTTACCGCCGCAACAACACCCCCAGAGAAAGGTATCGAAAATGGACAGCTAACATCAACGCCCCGTTCTGCCAGcacgcccacgcccaccaAGCCAGACACCGAACGGGAATCCGAGCTGGAGTCGAGCTGCTATTCGTGCGGCTACTGCGACAAGAAGTTCCGCTATGAGAACAATTTGATTATCCATCAGCGGACGCATACCGGTGAGAAGCCGTATAAGTGCACCGCCTGTGACTTTGAGTGCTCGCACATACAGAAGCTAATGAAGCATATGCGGGTGCATCGCAGTCCAGCCGATCACGGACACGATGGCGGCGATAATCAGGATGGTCACGATGGCGGCAGCAATGCCGATTCGCTGGAAACGAACGAGGCGGACAACGATGACGATCCCAATCCCGATGAGTCCGACGAAGAGCTGAACGACGAGGATGCGGACGCTGATGCCGATGGCGAGGAGGATGACGAGGATGAGCTAGACGATTGCGATGATGTTGATTACGAGGCCGAAGATCTGAGCGTCAACAATCGCATCGATGGCAAAAGTCAAAGCCCCAAAACAACCAGCTCCGGTGCCACATCGCTGGTGGGTGAGCTGATGGACAAGTTCGGGCTCTCCAACATTGCCCAATATTCGGAGGCGTACAAGCAGGCGCTGCAGGAGTCCGGGCGCAAGGAAGCAGCCGCTGtggccgctgccgctgctgccgccgccgctgttgtcgacaacaacaatcgtgGCTCGGCAGCCGGTGCAGCGAATCCAGGCGCTGGTAGCGGCGTCGCCTCCACCCAGCCACTGGGTGACAAGCTTAACGGTCTACCGGTGGCAGCGTTGCGACTGCGCGATGAATTCGCCAAGAACTGCAATATGTTCCAGCCACAGCCGCAGGATGCGCCGTCGCAGGTGCCGCTATTCAATCCGTTTCCCAATCCCTTCGAGCTGTCCAAGCGCATGAAGATCGATGGCGGTGATTGGTGGGGCATGTCCGCCCTGCATCGCAACGAGGCGCTCTTCGAGAACCTCAAACTGAAGCCGTTGGGTCTGGGCGGCGCCAACTCGCTGCTGCAAGGACCGCTGCTCAAGAAGGAGAGCCGGCAGCGCAACGATACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAATCTAACGGTGCATCGTCGCAGCCACACCGGCGAGAAGCCATACAAGTGTGAACTGTGCTCCTATGCCTGCGCCCAGAGCTCGAAGCTCACGCGCCACATGAAGACGCACGGACGCACCGGCAAGGATGTGTATCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTCCCCTCCACCCTCGAGAAGCACATGCGCAAGTGTGTCGTCAATCAGGGcaaggcggcagcagctgctgcaaatgcagcCAATGCAGTTGCCGCTGCCCAAGCCGCCGCTGCCGCACAGCAACTGCAGGCCGCTGCTcaggcacaacaacagcagcagcagcaacaacagcaacagcaacagcagcaacagttgccatcGCAATCGCAGCTATCTCCGCCGTGTGCAATGGGCGTGGCTGTCGGCTATCCGCCGCAATTCGGACACAATCTGTCCCTGGCGGGCAGCGTGAGTGGCGACAATGATTCGAATGCATCCTCCAGCCTGCCAGCGCACTCCTCCATTTCGCTCAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPVAGSGATVAANAIASAAAATAAAAAAATAAAAAAAVASSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADSDALTTATGAAGLESSIAHSPRAQLAQGQLIGREECALHDDKPKVKQEPYADDEQLDEEVELEQAPEQEQQQERDREQEQERERELNAQLLTQATDRDECQQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVETGGCGATLTVATPAALNAAATAAAAQATSVSVSPNRSLSPAAATVGSVSLPLPLHALMAQSPAPKRSSSNSSAAAAAAAAAAAAISAGSANTSSNSSSNVSSSSNSANSPTQQLLQQRVQQQQQQQQQQQQQQQQQQQQQQQQSLALAAGMRHHALLAPPDSLHANPFQLLRMPLPPALSQSNVVPSVSPLFGRPTPADHYRMEQLVSEQFRHHGFSLAAAAAAAQAQFNANTQQQQQQQQQQQPAQPIAVNVPNPVEQRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQVAAAAAAAAAALSPAASLNLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSASLSVTAATTPPEKGIENGQLTSTPRSASTPTPTKPDTERESELESSCYSCGYCDKKFRYENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADHGHDGGDNQDGHDGGSNADSLETNEADNDDDPNPDESDEELNDEDADADADGEEDDEDELDDCDDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVVDNNNRGSAAGAANPGAGSGVASTQPLGDKLNGLPVAALRLRDEFAKNCNMFQPQPQDAPSQVPLFNPFPNPFELSKRMKIDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQQQQLPSQSQLSPPCAMGVAVGYPPQFGHNLSLAGSVSGDNDSNASSSLPAHSSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00616427;
90% Identity: iTF_00558986;
80% Identity: -