Basic Information

Insect: Drosophila picticornis
Gene Symbol: Clamp
Assembly: GCA_035043845.1
Location: JAWNMR010000491.1:14957442-14959625[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0001 0.0063 16.8 1.2 1 23 132 154 132 154 0.99

2 7 0.0002 0.012 15.9 0.7 1 23 377 399 377 399 0.97

3 7 4.4e-06 0.00027 21.1 0.1 1 23 405 427 405 427 0.99

4 7 2.9e-06 0.00018 21.7 3.2 1 23 433 455 433 455 0.99

5 7 3.2e-06 0.0002 21.5 0.3 1 23 461 483 461 483 0.98

6 7 1.4e-06 8.7e-05 22.6 0.4 1 23 489 511 489 511 0.98

7 7 6e-05 0.0037 17.5 0.1 1 23 517 539 517 539 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0001	0.0063	16.8	1.2	1	23	132	154	132	154	0.99
2	7	0.0002	0.012	15.9	0.7	1	23	377	399	377	399	0.97
3	7	4.4e-06	0.00027	21.1	0.1	1	23	405	427	405	427	0.99
4	7	2.9e-06	0.00018	21.7	3.2	1	23	433	455	433	455	0.99
5	7	3.2e-06	0.0002	21.5	0.3	1	23	461	483	461	483	0.98
6	7	1.4e-06	8.7e-05	22.6	0.4	1	23	489	511	489	511	0.98
7	7	6e-05	0.0037	17.5	0.1	1	23	517	539	517	539	0.97

Sequence Information

Coding Sequence: ATGGAAGACCTCACCAAGAACATAATATTCACAAACGCCATCAACGGCCAACCGACAACGATTCAATACCAAACAGCAGACGGCACCATTCTCAAACAACCCAAAATCGAGGGCCAGAAGGCCGATCAACAGCCCACCTTTTACTACACAACAAATGGCAATGGCGGCACGGTGAATCTGGCACAGTTGGCCACCACAGACGACAATAAGACTTGCTACATTACACAGCCAGTGGGTGGCTACAATTATGCTTTGGTCAACGGAATGCCCCTCAATCAGGGCACTGTGGGCATCGCCACTGTAGATGCACAAGGACGCATACAGATTGTCAATCAAAATAAGCCAATTGCAGCGACAATTTCACCGCTGCAAAACACAATATCAAACATTAGCTTCAAGTGTGATGTCTGCTCGGAGATGTTTCAGCATTTGGCACTGCTCAACGCTCACAAGCGGATGCACGCAGATGGCTCCGATCCGCAGCAGCATAACTCACAGCAATCGAATGATGCCATCGCGGTGGTTAATGCACAGGGTCTGGTGCAGACGCAAAATATAATCACCGGCAATGGACAGATGGGTCAGATACAAATCGTTGCTTCCGATTCACTGGAGCCAGTGCAACAGTCCgtcatgcagcagcaacagcagcagcagcagcaacaacagcaggcatcacaacagcaacagcagcacgaCAATTCCAAGTCGAGCAAGTGCATCAATTGCGGCACTGCCATGATGCAACAGTCGAAGCGCAAGGGTCCCAAGCAGGTGCGCTGCGAGTCCTGCATGCAGGCGGAGCAAGCGGCGCAACAACAGATATTTGTGGCGCCCGATGGTCAAATGGCGCATCCTGTACAAATCATATCAACTACACCCCAGGCGCAAGCTCAGCTTCAGCAGATTGTTGCGCAGCAAACTGGCAGCACAACTCCCAAGCGAGAGCCGAGCGCATCCGGCCATCATCCGGTAAAGAAGCGCAACTCCCAACAGATGACCAAATGTCAAAAGTGCAATGGTTCCGGCGTCGTTCTAATgggtcaacacacacatacacatacaggCGCCAGTGGCTCCGTCAAACAAAATTCTGTCACCGTGAAGACCGAaAATCCCAGTAAACCCTTCAGCTGCAACATATGCGGCGGCCTCTTCTCACGCTACTCCAGCCTGTGGTCACACAAGAAGCTGCACAGCGGCGAGAAGAACTACAAGTGCACCATCTGCGGACTGGCATTTGCCAAGGCCGTCTACCTTAAGAACCATGCGCGCATACACACTGGCGAAAAGCCCTACAAATGTCAAACTTGTGGAATGCAGTTCTCGCAATCGCCGCATCTAAAGAATCACGAGCGCACGCACAGCGGCGAACGTCCGTATGTGTGCGGGGTGTGCGACAAGGGATTTGCGCGTCATGCCACGCTGTGGAATCATCGTCGCATACACACCGGCGAGAAGCCGTACAAGTGCGAAATATGCGGCTCGGCCTTTTCGCAGGCGGCACACCTGAAGAACCATGCCAAGGTGCACTCCGGCGAGAAGCCGtacaaatgtgaaatatgctCGGCAGCGTTTGCCGATCGTTTCGCGTTGAAACGCCACCGGGGCATACATCAGAAGTATGGACAAACCGCGCCCAGGCAGCCGGCTGGTGATGGCATGGTCGTGCACAAGCAGGAGCTGCCCGACATGGATGACGATGCGCAACAGGAGGTGATCATCGGCGGCTTATAG
Protein Sequence: MEDLTKNIIFTNAINGQPTTIQYQTADGTILKQPKIEGQKADQQPTFYYTTNGNGGTVNLAQLATTDDNKTCYITQPVGGYNYALVNGMPLNQGTVGIATVDAQGRIQIVNQNKPIAATISPLQNTISNISFKCDVCSEMFQHLALLNAHKRMHADGSDPQQHNSQQSNDAIAVVNAQGLVQTQNIITGNGQMGQIQIVASDSLEPVQQSVMQQQQQQQQQQQQASQQQQQHDNSKSSKCINCGTAMMQQSKRKGPKQVRCESCMQAEQAAQQQIFVAPDGQMAHPVQIISTTPQAQAQLQQIVAQQTGSTTPKREPSASGHHPVKKRNSQQMTKCQKCNGSGVVLMGQHTHTHTGASGSVKQNSVTVKTENPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCTICGLAFAKAVYLKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIHQKYGQTAPRQPAGDGMVVHKQELPDMDDDAQQEVIIGGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537677;
90% Identity: iTF_00479637;
80% Identity: -