Basic Information

Insect: Drosophila phalerata
Gene Symbol: ken1
Assembly: GCA_951394115.2
Location: OX596004.2:37750479-37752716[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0053 0.53 11.4 5.1 2 23 225 246 224 246 0.97

2 12 0.00028 0.028 15.4 2.3 1 23 252 277 252 277 0.95

3 12 0.00014 0.014 16.3 0.1 3 23 287 310 285 310 0.93

4 12 0.00054 0.054 14.5 2.6 3 23 322 342 321 342 0.97

5 12 0.00048 0.048 14.7 1.2 3 23 351 371 349 371 0.97

6 12 0.0042 0.42 11.7 0.5 1 23 377 399 377 399 0.97

7 12 0.011 1 10.5 1.9 1 23 405 428 405 428 0.97

8 12 0.034 3.3 8.9 3.9 1 23 434 456 434 456 0.95

9 12 0.037 3.6 8.8 1.9 2 23 463 484 462 484 0.94

10 12 0.0022 0.22 12.6 0.8 1 23 569 592 569 592 0.95

11 12 0.0015 0.15 13.1 2.7 1 23 598 620 598 620 0.96

12 12 6.7e-05 0.0066 17.4 5.0 3 23 628 648 626 648 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0053	0.53	11.4	5.1	2	23	225	246	224	246	0.97
2	12	0.00028	0.028	15.4	2.3	1	23	252	277	252	277	0.95
3	12	0.00014	0.014	16.3	0.1	3	23	287	310	285	310	0.93
4	12	0.00054	0.054	14.5	2.6	3	23	322	342	321	342	0.97
5	12	0.00048	0.048	14.7	1.2	3	23	351	371	349	371	0.97
6	12	0.0042	0.42	11.7	0.5	1	23	377	399	377	399	0.97
7	12	0.011	1	10.5	1.9	1	23	405	428	405	428	0.97
8	12	0.034	3.3	8.9	3.9	1	23	434	456	434	456	0.95
9	12	0.037	3.6	8.8	1.9	2	23	463	484	462	484	0.94
10	12	0.0022	0.22	12.6	0.8	1	23	569	592	569	592	0.95
11	12	0.0015	0.15	13.1	2.7	1	23	598	620	598	620	0.96
12	12	6.7e-05	0.0066	17.4	5.0	3	23	628	648	626	648	0.97

Sequence Information

Coding Sequence: ATGAATGAGGATACTACAGCCTCAATTCATACAATATGCCGCACCTGTTTGTCCAGCTTGGAGCACGATGAAGCCTTCGACCTGTTTGTTGTTCCGGGTCTGGCCAAgaagttgtgtgtgtgtacttcgCTGTCGGTGGAGCACCTGGATGGATTTCCCAGAAACCTCTGCACCACCTGTCACAGCCGTCTCAACGATTTGCACGACTTTCAGAAGCAATGCGTGGACTCTGTGCAAAAGTTCAAGGAGTTGGTGTCCAGAAACACCTTCATAATCCAAGCTATTCCAGAGGAAGATGTCACTGAAAAGGAGCACATTAACTTTGACCCACTGTTGGATACTAAAATGGAAATTGACAACGAGGCGGACGTTTTTAAAATGCTGGAAGATGTTGACAAGGAATCCGATGATGTAGATAATCTGGAGGATGCATTTAATGACAGCGGAAGCGACTATAACAATGAAGATGCTGACTTCCAAGTGGATAGCAGCGATTCCGATGATGATATGCCTCTGTCTCGCCTACGAAGTAATTCCAAGACCACAAAGACCAAGACCAAAAAGCGTGATGAAGAGCAGGAATCGTCAGAATCGAATGATGAAGATGATCCCAAAGAGAAACCGAAACGCAAGCGAGTTCCAGCTGCTGAGCGTCAATTACATCGCCTCCTTGAATGTCACGTCTGTCGCCAGAAGTTCAAGAAGGCGTCACGTTACGAGGAGCATATGAGACACCACAATGATCAATTGCCCTATCAATGTACAGTGGAGACCTGTAAGAAGGGATTTACGCAAGCCGCAGGACTGCGTCATCATATGGATCACACGCATCCGGAACTCTGCACGGATCGCATACCCTGTACAATCGATGGATGCGATGAATCCTTTCCACGCAATCGCATGCTCACCCAACATCTAAAGAAGGtgcatcaaattaaaaatccgGAGACTCGTAAGAATATATGCTCGGAATGTAACAAGGTATTCCGTTGTCCAACGGCGCTCAAGAAGCATATGTATAAGCACACGGGAGAGGCGCCTCCCATTGCATGCAACATCTGCAACAGACGCTTCCACATCAACAGCGAGCTCCGGGATCATCTGCTGCGTCATGCCGGCGTCAAGAATCATGTGTGTCCGTATTGTGGTGTGGGCAAGACCACAAAACAGGAGTGGAACAAACACATCTTGACGCACACCAGGGAGAAGCAGTTCAAGTGTTCTCAATGCGATCATGCCTCCCACAACAAACAGGCGCTGGCCAATCATGTCAAGGTCGTCCACATGAAGATCAAGAACTTTGCGTGTCAATATTGTGGCCGGACCTTTGGCAAATCCCATGCCTGCAAGGTGCACGAGAGATTGCACACGGGAGAGAACTGTTGCGAGTGCAAGATCTGTGGCCAGGTCTTTCTCTTCGAGAAGAGATTAACGAAGCATCTGCTGTTGCATAAGAAGCGTGATATACCAGATGATAAGGCTCCAGCTGAAGGAGATGCAGAGGAGGAGCCTACAGAGCCCATCGATGTGAAGGACGAACCAAAAATGCCGGTCCAGCCAAATATTCCTGCCAAGCCAAAGAAGTCACGTCGTGTGGAGCGTGTGGACATCTCTGAACTAGCTGGCACCATTGTCAACCCAATTTCATCGGTATCCGTTCCCTCCTGGTCACCGCAAGTCAACTTCACCAAGAAGGAGGGCCAACACATTTGTCCAGCCTGTGGACGTGGCTTCAATCACATTGGCAACATGAAACTCCACTACAAAGTCATCCACGAAAAGATCAAGGACTTTGCCTGTCGTTACTGTCCCAAGCGCTTTGGAAAGGCACAATATCTGCAACATCATGAGTATACACATACGGGCGAGAAGCCGTATGGTTGTAAAATATGCGATAAGCATTTCAGTCATGGTTCATCCCTAAGGAAGCACATGTTCTCACACAATCGACCTCCAAAGGCGCCAAAGGATCCGAAGCCTGCGCCCAAGACAAAGGCCCAAGAAGAGATACCCAAAATAAAGCTAAATAAACATCGACGGATAATTAATTATGAACAGTATCAAGATCCAGCTGCGGAACAAGCGGCTGCAAAGGCGGAGTTAATCGCCCAGCAGCTGGACGAGAAGGAGGCGAAGCGCATCGAGGAAGAAAAAACCCGGGAAATTCAGGAGGCAGCCTGCGAACAGCTCCAGAAATTGCAGCAGCAAATGTCCTACGACAACTTTGCTGCAACATAG
Protein Sequence: MNEDTTASIHTICRTCLSSLEHDEAFDLFVVPGLAKKLCVCTSLSVEHLDGFPRNLCTTCHSRLNDLHDFQKQCVDSVQKFKELVSRNTFIIQAIPEEDVTEKEHINFDPLLDTKMEIDNEADVFKMLEDVDKESDDVDNLEDAFNDSGSDYNNEDADFQVDSSDSDDDMPLSRLRSNSKTTKTKTKKRDEEQESSESNDEDDPKEKPKRKRVPAAERQLHRLLECHVCRQKFKKASRYEEHMRHHNDQLPYQCTVETCKKGFTQAAGLRHHMDHTHPELCTDRIPCTIDGCDESFPRNRMLTQHLKKVHQIKNPETRKNICSECNKVFRCPTALKKHMYKHTGEAPPIACNICNRRFHINSELRDHLLRHAGVKNHVCPYCGVGKTTKQEWNKHILTHTREKQFKCSQCDHASHNKQALANHVKVVHMKIKNFACQYCGRTFGKSHACKVHERLHTGENCCECKICGQVFLFEKRLTKHLLLHKKRDIPDDKAPAEGDAEEEPTEPIDVKDEPKMPVQPNIPAKPKKSRRVERVDISELAGTIVNPISSVSVPSWSPQVNFTKKEGQHICPACGRGFNHIGNMKLHYKVIHEKIKDFACRYCPKRFGKAQYLQHHEYTHTGEKPYGCKICDKHFSHGSSLRKHMFSHNRPPKAPKDPKPAPKTKAQEEIPKIKLNKHRRIINYEQYQDPAAEQAAAKAELIAQQLDEKEAKRIEEEKTREIQEAACEQLQKLQQQMSYDNFAAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507084;
90% Identity: -
80% Identity: -