Basic Information

Insect: Drosophila phalerata
Gene Symbol: -
Assembly: GCA_951394115.2
Location: OX596005.2:12391202-12394394[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0002 0.02 15.9 5.5 1 23 167 190 167 190 0.97

2 16 0.0013 0.13 13.3 3.1 1 23 241 264 241 264 0.96

3 16 0.00064 0.063 14.3 3.3 1 23 330 353 330 353 0.96

4 16 0.0031 0.31 12.1 0.4 2 23 405 426 404 426 0.97

5 16 2.9 2.9e+02 2.8 0.7 1 20 539 558 539 560 0.75

6 16 0.02 2 9.6 0.6 1 23 569 591 569 591 0.94

7 16 0.00029 0.029 15.4 2.1 1 23 598 620 598 621 0.95

8 16 0.00036 0.035 15.1 1.4 2 23 629 650 628 650 0.96

9 16 0.0015 0.14 13.2 0.2 3 22 678 697 676 700 0.89

10 16 0.0033 0.32 12.1 0.8 1 23 737 760 737 760 0.96

11 16 0.11 11 7.3 1.5 1 22 767 788 767 788 0.97

12 16 0.0039 0.38 11.8 0.6 1 23 797 820 797 820 0.97

13 16 1.6e-05 0.0016 19.3 0.5 1 23 839 862 839 862 0.97

14 16 0.039 3.8 8.7 0.2 1 23 872 894 872 894 0.94

15 16 1.1e-05 0.0011 19.8 1.7 1 23 900 922 900 922 0.99

16 16 5.3e-05 0.0052 17.7 0.9 1 23 928 950 928 950 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0002	0.02	15.9	5.5	1	23	167	190	167	190	0.97
2	16	0.0013	0.13	13.3	3.1	1	23	241	264	241	264	0.96
3	16	0.00064	0.063	14.3	3.3	1	23	330	353	330	353	0.96
4	16	0.0031	0.31	12.1	0.4	2	23	405	426	404	426	0.97
5	16	2.9	2.9e+02	2.8	0.7	1	20	539	558	539	560	0.75
6	16	0.02	2	9.6	0.6	1	23	569	591	569	591	0.94
7	16	0.00029	0.029	15.4	2.1	1	23	598	620	598	621	0.95
8	16	0.00036	0.035	15.1	1.4	2	23	629	650	628	650	0.96
9	16	0.0015	0.14	13.2	0.2	3	22	678	697	676	700	0.89
10	16	0.0033	0.32	12.1	0.8	1	23	737	760	737	760	0.96
11	16	0.11	11	7.3	1.5	1	22	767	788	767	788	0.97
12	16	0.0039	0.38	11.8	0.6	1	23	797	820	797	820	0.97
13	16	1.6e-05	0.0016	19.3	0.5	1	23	839	862	839	862	0.97
14	16	0.039	3.8	8.7	0.2	1	23	872	894	872	894	0.94
15	16	1.1e-05	0.0011	19.8	1.7	1	23	900	922	900	922	0.99
16	16	5.3e-05	0.0052	17.7	0.9	1	23	928	950	928	950	0.98

Sequence Information

Coding Sequence: ATGACAAGGACATGTAGAATTTGCGGTGGCGCAGATGGACGCTATTGGATTGAGACGCCTGTCGATAAATATGCAGAGAAGACATTCAATCAACTGCTGCTAGAACTAACCAGACTTGAGGTCGCCTTGGATCAAGCAGACAAGCTGCCGCCCTGGCTTTGCCGCAGCTGTGCTCAAAGGTTAGAAAATGCATATGATTTTGTCATGCAAGCGCGTAAAACTCACGAGCTTTGGATCCAGAAAATGGGAACAGAAGCAGCTCTGGATGATGCTGAAAAGGGCACTTTAGAATGCCTGCGAGAGACACCCATACAATTGCTGGAGATCGAGGGAGTGACAATTAAAATGGAAGAGCAATCCGAACCTGCCATGCCACAAGCAAACCCAGCAGTTTCAGTTGATCCTCTAATTAAGAAAAACATAGATGATGCTagcgatgatgatgacgatgtgCCGCTGAAACAACGCAAAGCCCAACACGTCAAGTTATCCATGCAACACCAATGCAATAGATGCGACAAGACCTTTAAATATGTTACAAATCTCTTCAGGCACAAGCAGCGAGATCACAGTCCTGTTCAATGCAAGCCAAGGAACAAATCAGGAGTGGAAAATACAGGTGCTGACCGTCCCGTTTCATTTCTGCACAACCTTATAAGGAGTTCCACGGTGGAACGAAGCAGCGCTAACTCCGACATGGACAACGAAGCTGACAACTACTACAAATGTGATCAATGCGACAAATCATATAAGTACATAATGCTCCTGATTAAGCACAAGCACAAGGCTCACGGCGCCAACCAGTTGCCAGCAGAGCCAAGGCCAATTCGAAGAAGCGAATCGAGTTCAGAACAAACATCTAATTTCAGAACAAGTCAGCGTCAGCGGTCAAAAGCCCCCAGTACAGATTCACTGGTGCATAGCTTAAtcaaagagataaaAACACCTGAGGAAGATGACCCAGATAGTACAGGTGCCGACAACTATTACAAGTGCGATCAATGTGACAAGTCCTACAAATACATTGTAAGTCTCATCAAGCACAAACATAAGGAGCACAATGAGTATAAGGACtccgatgaggatgaggaagaAGCATCTTCATCGCCATATGCTACAGCGACAGCTTCAATGTCAAAGCCTTCACGCATAGATCGAAGAGTCAAGGGCTTCGATTTGCATCGGTGCAAGCCAAATGGTTCCAAAGAGATTCAATGTATGATCTGCCTGCGAAGATTTGTTAAACTGAGAGAGCTGCGTGATCATCTCAGAGCACATCCCAGAGATTTTACCTTCGATTCTCACGCTGAGCCCATTGAACGAATTGCTGAAGGCTTTTATAGGACCGCCGTGGAATCGACGGCAGTCGGCTTGAAAAGGCGTATTCTAAATGATCTCAAGATTGGCATGTATGGCCGCTATTATTCCATAACCAATGAGGCGCGTTACGAGATGAATCTGGACAGCTCGGACACGGATAGTGATGGCGAGGCAGGTGTTGTTGAGCGTCGTAGTTATGCCTGCGAATTATGTGACTCGGCCTCAGCCATTTGGTCGCGAAAATTTCAACTGCATGAGCATCATCGTCAGCAACATACTTGGCTGGAGGCACCCTACGTCTGTCAGCGTTGTGACTCCCGTTTTCTGAGCGCCCAGTTGCTCGACCATCACACTCAAAAGCTCTGCCAGAATACCCTAAAGCGTTTCATGTGCGACAAGTGTCCGCAACGGTTCTTCTGGCGTCGTAATCTTCGTGCACATCTCGTGGAGCATAAAAACAAGcAAGAAAATTACCCATGTGATCAGTGTTCACGCAGTTTTCAGGATAAAAGCGCCGTGACGAAACACAAACTAATGCATCACGATGTCGGCAATGACCTGATACCTTGTCGCTGGTGCACACGGACATTCTATCGCCCAGCCCTGCTTCATAAGCATGTGAAACGTCATGGCTTCAGTGGAGAGGATCTGCCCTTGGCTGAGACACTGCTGGCGGATGCCGCCAAATCATCCGGACCAAAGACGATTATTTGCAAGCTATGCGATATGCATTTCGTTAGTATTGCCGATTTGCGAAGACATATTTCAATGCAGGCACATAGCGACGAGTTTCGCAATTATATGATAAGCACAGAGGATGGATTCGAACTGCAGCTGGACGAGACAGACGATAGCGATGATGAGACCACTGGATCTGCTGGCAGGTCCTACAGGTGTGATCTATGCGACATGGCCTTCCAGCGTCGAAGGGACATGAGCGAACATCAGTATTCCTTGCACACATTCGATAAACTACCCTATTCCTGTGAGCATTGCATCTACAAGACAGTTGATAAGAACATGCTGGAGCATCATTTGCGCACACAGTGCCTAAACCAGGAGAAGAAATTCAAGTGTTTGCGTTGTGGCTACAAATTTATGTGGAATGAAAATCTGGAACAACATATGGCCAGCCAACATTCCAAATCATCTAATCAGACACCCGTAGCGACCAAGCGAAGTCGACGCTTTAGATATCAGTGTCCGCATTGCTGGCGTTCCTTTGTGGTGCAACCCAGTCTGGACAAGCATATACGCGACATGCATGTGGCCAAAAAGAATCCCGGCAAGAAGTATCTATGCTCATTATGCGGCCTGGAATCGCTCACCCCCAACAAGCTTAACATCCACATGCGTCGTCACAACGGCGAGAAACCATTTAAATGTGATCTTTGTGACATGTCCTTCACAGTTTACTATGAACTAAAGGTTCATCGTCGAAAACATACAGGCGAGCGACCCTATCAATGTACTTTCTGTGCCAAGGATTTCGCACGTCCGGACAAGCTTAGACGACATGTTTACATGCACAGCGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGADGRYWIETPVDKYAEKTFNQLLLELTRLEVALDQADKLPPWLCRSCAQRLENAYDFVMQARKTHELWIQKMGTEAALDDAEKGTLECLRETPIQLLEIEGVTIKMEEQSEPAMPQANPAVSVDPLIKKNIDDASDDDDDVPLKQRKAQHVKLSMQHQCNRCDKTFKYVTNLFRHKQRDHSPVQCKPRNKSGVENTGADRPVSFLHNLIRSSTVERSSANSDMDNEADNYYKCDQCDKSYKYIMLLIKHKHKAHGANQLPAEPRPIRRSESSSEQTSNFRTSQRQRSKAPSTDSLVHSLIKEIKTPEEDDPDSTGADNYYKCDQCDKSYKYIVSLIKHKHKEHNEYKDSDEDEEEASSSPYATATASMSKPSRIDRRVKGFDLHRCKPNGSKEIQCMICLRRFVKLRELRDHLRAHPRDFTFDSHAEPIERIAEGFYRTAVESTAVGLKRRILNDLKIGMYGRYYSITNEARYEMNLDSSDTDSDGEAGVVERRSYACELCDSASAIWSRKFQLHEHHRQQHTWLEAPYVCQRCDSRFLSAQLLDHHTQKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQENYPCDQCSRSFQDKSAVTKHKLMHHDVGNDLIPCRWCTRTFYRPALLHKHVKRHGFSGEDLPLAETLLADAAKSSGPKTIICKLCDMHFVSIADLRRHISMQAHSDEFRNYMISTEDGFELQLDETDDSDDETTGSAGRSYRCDLCDMAFQRRRDMSEHQYSLHTFDKLPYSCEHCIYKTVDKNMLEHHLRTQCLNQEKKFKCLRCGYKFMWNENLEQHMASQHSKSSNQTPVATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMSFTVYYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579434;
90% Identity: iTF_00528986;
80% Identity: -