Basic Information

Insect: Drosophila persimilis
Gene Symbol: -
Assembly: GCA_003286085.2
Location: NW:2024934-2068748[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.5 4.2e+02 1.4 4.8 3 23 294 316 292 316 0.92

2 14 4.2 2.4e+02 2.2 4.2 3 22 465 484 463 487 0.91

3 14 0.027 1.5 9.1 0.3 2 23 509 531 508 531 0.94

4 14 2.1 1.2e+02 3.1 0.2 1 23 548 571 548 571 0.84

5 14 0.12 6.6 7.1 0.5 1 21 576 596 576 600 0.90

6 14 0.0024 0.13 12.4 0.1 2 23 646 668 645 668 0.92

7 14 0.11 6.2 7.2 0.1 3 21 675 693 674 694 0.94

8 14 0.45 25 5.2 1.7 2 23 714 735 713 735 0.92

9 14 0.00017 0.0097 16.0 1.1 2 23 748 768 747 768 0.97

10 14 5.2e-06 0.00029 20.8 1.4 1 23 774 797 774 797 0.97

11 14 0.0062 0.35 11.1 0.3 1 23 851 875 851 875 0.98

12 14 0.031 1.7 8.9 3.4 1 23 880 905 880 905 0.96

13 14 0.013 0.73 10.1 0.9 1 23 913 935 913 935 0.96

14 14 0.41 23 5.4 5.4 1 22 941 962 941 966 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.5	4.2e+02	1.4	4.8	3	23	294	316	292	316	0.92
2	14	4.2	2.4e+02	2.2	4.2	3	22	465	484	463	487	0.91
3	14	0.027	1.5	9.1	0.3	2	23	509	531	508	531	0.94
4	14	2.1	1.2e+02	3.1	0.2	1	23	548	571	548	571	0.84
5	14	0.12	6.6	7.1	0.5	1	21	576	596	576	600	0.90
6	14	0.0024	0.13	12.4	0.1	2	23	646	668	645	668	0.92
7	14	0.11	6.2	7.2	0.1	3	21	675	693	674	694	0.94
8	14	0.45	25	5.2	1.7	2	23	714	735	713	735	0.92
9	14	0.00017	0.0097	16.0	1.1	2	23	748	768	747	768	0.97
10	14	5.2e-06	0.00029	20.8	1.4	1	23	774	797	774	797	0.97
11	14	0.0062	0.35	11.1	0.3	1	23	851	875	851	875	0.98
12	14	0.031	1.7	8.9	3.4	1	23	880	905	880	905	0.96
13	14	0.013	0.73	10.1	0.9	1	23	913	935	913	935	0.96
14	14	0.41	23	5.4	5.4	1	22	941	962	941	966	0.93

Sequence Information

Coding Sequence: ATGGACTCTGACGATCTAGATGACACTCATCTGTGCATTAAATGCAATGCCACCATCGTGGGGCTCTCCAAGTACATCGAGCACCGCAAAAGCAATTGCCTGGCCGCACAGAAAACCCAGAGACCCAAAACACCAGAGGCCACGTCTCCTGCCACTCAAGAGGTCTCGCCACCTGCGATCCTCAGTAGCAGACATTTGGATCACACGTACGATAGCTTTCATTTCGCCGAGCCAGAGGCCCCCAGCAGCTATTTGAGAAAGACGACAGCCAGTCATGGGGGAAAGTCCTCCAAGTCCTTGACAGAAGCCTACGATCTTCCCTACGAACTAGGGGCAGATTTGTTCTTCTCTTCCCTGCAGTTGCAGAGTGTTTCGACGGGCGGAAAAACTGTGTCCAGACCAAAAGAAGAGGCCTGGGATGGGTCGAGTCGAGCGGCCAAGGAAGAGGCCTGGACTGCGGCTAGAGATCCTGTACTAAAGGCAGTCCGAGAACACGATGAGGCTGTCTTTAAGCCTCTGAATTTCGTTCAGGACTCGCCGGAACCCAGCGACGAAGAGGATGAAGACGAAGACGATCCGGATGACTCGTTCGATGCGGAGGAAGACGAAGCCGAAGAGGAGTACGATGCGGTGCAGCACTCGCCACCCGCAGTGCCTGCCACACACACGGGGGGCAAGTGGAAGCCGGAGCATCGGCCCCAGTTAGGGCACACCCACATCGAAAGGATTTCCCCCAGCTGGGATGAGCCGGCGGAAGAGGTCTATGCCCATCCCCCAGAGGAGCACACTCACGGCAAGTGGGTGCCCGGCAGCAAGCAGCTGGAGTACCGCGAGAATATCGACCTGACGAAGCTGCAACAGCCGGGCGTCAGTTATTGGTGCAACATCTGCTGCAGGCGGTTGAAGAGTCGCTGCAACTACGAGCAGCATTTGCGATCGGCATACCATTTGAAGAGAGCGGAGGCGGAACGCCAGCTGGAGCAGGCCACCCTCGGGGGGAAGCTCCCGCTAAGCAAGGACTTCAGCCCGCCGGAGAGGGaggaacagcagccaacagaAGAGGAGCCAATGGCAGAGTCGGAGATCCCTAAAAGGAAACGCCGTGCGCATTTCTTGCGCTGCGATCTGTGCCACCACACGATGGGCCGGCATTTGATGGGCAAGCACCTGATCTCGCACTATCACTACAGACGcctccagcagcagacgcCGCTGCGAAGGCAGTCCTTCCTCAAGGACATACTCGACCACATGGGCAGCATTGTGCGGCAGTCGCCGTTCCAGTGCCAGCCCTGCAGCTTCTATGCCAACACGGAAGAGGCCTTCCTGCGGCACTGGCGATCCGCAGAGCACTTGAAGCAGGTCCAGGGGCGCAGAGGAGACAGCTTTTGGTGCAGCTACTGCCAGTTCGAGTGCGAGTCCAGCGACCTGATGTGGCAGCACATGCTGCACCCGTGCCACAAGGATGTGGTGCTGGCCCTCAACCGATCAGTGCCCATCTGCATTGCCCAGCGGAGTCGCCTCCAGTGCTCCGCTTGCGGCGAGAGCTTCCTCTACAACATGCAGCTGCGCCGCCACTTTGCCACGGAGCATCCGGGCCTGCCGCCCACCGACACGGCCGCCGACGACTACCAGAGTCGCTTTCGCTGTGGCATATGCGGAGCGCCACAGATGTCCCGCCTGGCGCTGCAGCGGCACGAGAAGTTCAAGCATCGCCTGGAACGGTACTACTGCGGCATCTGCCACCTGGAGTTTGAGACGGCGCTGGAGGCACGTCGTCACCGGAGTCTGTTGCAGCACAAGCTGCGGTCCAACCCGAAGGACAGGGTTGCCCCGCAGTCGGACAAGGTCCTGGAGCGCATGCTACGCGAGGTCCTGGAGGATCAAAGGCCAGATCCCCCGCCAAAAAAGAAGCGACTGGTCGTGGCCTGCAAAcaatgcgccaactgccagaaGGTCTTTGACTCCCCCCAAGCCCTGGCCCAGCATCGAGCGGAGGCACATCCCGCGGAAAATCACGGCTGTCTGATCTGCGGCGAGAACTTTCACTCCCCCCAGGCCCTGGGGAGGCACAACCGCAGCTGCCAGCCCACAGCCAGCACCTCCTCCGCTGCCACTACAGGCAGCAGCAAGTCCTGGAGCTGCGATCAGTGTCCGTTCAGCTGCGAGTACGAATCGGATCTGCTATATCATCGATTCTTTCACACTCGATCGGGGTCCATTGGCCGCAACGAGATGCTCCAGTGCCCGCGCTGTCCAAAACGCTTCAAGATGTACTCCCTCAGGGCGCATCTCAGAACCCATACGAATGAGAAGATCTTCGAGTGTCCCGAGTGCCAGATGAAGTTTGGCAGGCGACACAATCTCAAGAATCACATTGCCACGATGCACAGCAAGAAGgaaaagccaaagaaggaGAAACAGGAAGTAAGGAAACCCTGCGATGAAGAAAGACCCAAATACCCGTTGGCAGTATTCGGAAAAAAGCTGGCAAATAGGAGTTCCCAAAAGCATCACGAGCAGAGCCATGCCTCGACTGTGGAGCGTAGCTTTCGCTGTCATGTCGCAGACTGTACATATTCGGGTGCCACCCAGGTGAGCCTCCGCATCCATTTGGCCTCTCATTCCCAGGGAAAACACAAGTGCGACAGGGACCAATGCAAGTATGTGGGAAAGAGCGAAGTGCATTTGAAAAGGCACCTCAAGTCGGTCCATGGCAAGGAGCAGGACAATTGGTTCCCCTGCGATCAGTGCGAGTTCAGGGCCCGCAGCAAGGACAAACTCCGACGGCACTCCATCAGTCATTCGGATGAGAGGCGCCACAAGTGTCCCCACTGCATTTTCCGATGCAAAAACATCGACAATCTACGCAAACACGTGATGAAAACGACCATGCATCCTGGCAAATTCATGTACGAGTGCAAAAAGTGCTCGGAACAGAAATCGAAGGAGATTTACAAGACCAACAACTACCAGGAATATAAGAGACATTTGACAACGCACCAAAAGAACTAA
Protein Sequence: MDSDDLDDTHLCIKCNATIVGLSKYIEHRKSNCLAAQKTQRPKTPEATSPATQEVSPPAILSSRHLDHTYDSFHFAEPEAPSSYLRKTTASHGGKSSKSLTEAYDLPYELGADLFFSSLQLQSVSTGGKTVSRPKEEAWDGSSRAAKEEAWTAARDPVLKAVREHDEAVFKPLNFVQDSPEPSDEEDEDEDDPDDSFDAEEDEAEEEYDAVQHSPPAVPATHTGGKWKPEHRPQLGHTHIERISPSWDEPAEEVYAHPPEEHTHGKWVPGSKQLEYRENIDLTKLQQPGVSYWCNICCRRLKSRCNYEQHLRSAYHLKRAEAERQLEQATLGGKLPLSKDFSPPEREEQQPTEEEPMAESEIPKRKRRAHFLRCDLCHHTMGRHLMGKHLISHYHYRRLQQQTPLRRQSFLKDILDHMGSIVRQSPFQCQPCSFYANTEEAFLRHWRSAEHLKQVQGRRGDSFWCSYCQFECESSDLMWQHMLHPCHKDVVLALNRSVPICIAQRSRLQCSACGESFLYNMQLRRHFATEHPGLPPTDTAADDYQSRFRCGICGAPQMSRLALQRHEKFKHRLERYYCGICHLEFETALEARRHRSLLQHKLRSNPKDRVAPQSDKVLERMLREVLEDQRPDPPPKKKRLVVACKQCANCQKVFDSPQALAQHRAEAHPAENHGCLICGENFHSPQALGRHNRSCQPTASTSSAATTGSSKSWSCDQCPFSCEYESDLLYHRFFHTRSGSIGRNEMLQCPRCPKRFKMYSLRAHLRTHTNEKIFECPECQMKFGRRHNLKNHIATMHSKKEKPKKEKQEVRKPCDEERPKYPLAVFGKKLANRSSQKHHEQSHASTVERSFRCHVADCTYSGATQVSLRIHLASHSQGKHKCDRDQCKYVGKSEVHLKRHLKSVHGKEQDNWFPCDQCEFRARSKDKLRRHSISHSDERRHKCPHCIFRCKNIDNLRKHVMKTTMHPGKFMYECKKCSEQKSKEIYKTNNYQEYKRHLTTHQKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581144;
90% Identity: iTF_00581144;
80% Identity: -