Basic Information

Insect: Drosophila persimilis
Gene Symbol: -
Assembly: GCA_003286085.2
Location: NW:194958-204278[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 3.5 2e+02 2.4 0.7 5 23 40 59 36 59 0.86

2 8 0.033 1.8 8.8 0.6 1 23 498 520 498 520 0.99

3 8 0.0039 0.22 11.7 0.6 1 23 528 550 528 550 0.97

4 8 0.00032 0.018 15.1 1.1 1 23 559 581 559 581 0.98

5 8 4.2e-05 0.0023 17.9 0.2 3 23 655 675 653 675 0.97

6 8 0.0024 0.14 12.4 1.1 1 23 683 707 683 707 0.98

7 8 2.2e-07 1.2e-05 25.1 2.2 1 23 713 735 713 735 0.98

8 8 0.00023 0.013 15.6 0.1 1 23 741 763 741 763 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	3.5	2e+02	2.4	0.7	5	23	40	59	36	59	0.86
2	8	0.033	1.8	8.8	0.6	1	23	498	520	498	520	0.99
3	8	0.0039	0.22	11.7	0.6	1	23	528	550	528	550	0.97
4	8	0.00032	0.018	15.1	1.1	1	23	559	581	559	581	0.98
5	8	4.2e-05	0.0023	17.9	0.2	3	23	655	675	653	675	0.97
6	8	0.0024	0.14	12.4	1.1	1	23	683	707	683	707	0.98
7	8	2.2e-07	1.2e-05	25.1	2.2	1	23	713	735	713	735	0.98
8	8	0.00023	0.013	15.6	0.1	1	23	741	763	741	763	0.98

Sequence Information

Coding Sequence: ATGAGCGTGTTGGCGTATCCACGTACAAACGATGAGGAGATTTTTCGTCACTGCACAAAGGATTGTGGCGTCGTGACGGCCACCGAGGACTTCCAGTATTTCGCATTGCGCTGTATCTTCTGCAGCGAAAAGTTCCTCTACTTTGATTCATTCATTAGCCACATGCAAACGGTGCATCTGGGCACCGAGGGGCACGTTCCCCCATCCAGCCTCGCCCTCAGCTTTGGCGAGCCCATGTCCCTGTCGATGGACGAGGATGCCCTGCACGAGGGAATCCATCATAGAAATGGGCACCACTTTGACGAGATCGAAGACTTGACCGATGCGGACACCGCTCTGCTCGAGCCACAAATGGTCATCAAACAGGAGCTACCCGAACCGCCATgtagcgacgacgacgacgacgacgacgcggATCCCGACCACGATGAGGATGTGCTCCGTTTGCCGGCAGACGAAGACGATTCTGAGGCCATTGACGACGAAGAGGCCATCCTACCCGAAAGCGATGTGCCCGCAATTATTCCAAGACCGCGCCCCCGTATGAAGGTGACCAAGCCGCGTGTGGATGTCAAAAACGAACCCATCACCGCCGACGGTGATTCGTCGATGGATGATTATGCCGACCATGATCGGAGCTACATGGGGGACAATGAGAATGACAATTCGGGCGAATATTTGGACtacagcggcggcagcagcagcttcaaTACAGCGGCCAATCACATCTTCCCCGGCAACGAATCAACCGATTTTCTCAGCTATGACGAGATGGTCGAGGAGTCCCTCTTGGGGAGGGACCGTGAGCTTACGATGCACATCAAGGATCGCAAGATGATCCAATTCCTCATACAATCATATCAGCGCAATCCGTTCCTGTGGGACCACAGCGATGCCCAGTTCCGGGATCGTGTAAAGCGTGCCCGCTTCCTCGATTGGATTGTCCTGGAGTTTCAGAGCCGCTTCAACATCTCTCTGGCCAAGGATGCCATCACCAGGAAGTGGGACAATCTGCGCACCGTTTACAAGCGCGAATGCAATCGGATGGCCCTCGAGAAGACGAACATCAGTACGCTGTGGTACTTTAAGGAGCTGCATTTCCTCAACGAGGTCTACAGCTACAATTCCAAAATGTCCGATGCTGTCGTCAAGGAAACCTCATACCGGCGCCGATTCTCAGCCATTTGGAACGACACATCGACAGCAAAGTTGCTGAGCATGGTGAAGCGATATCAGTGCTTCTATAACCGCTTTGATCCGGACTACCGCAGCAAGGAGCGTCGAGGCGAGGGCCTGCACCAGATGGCCAtggagctgcagcagctgaTTGATGTGTCCACCATCCAGATCTCGAAGCGCATCTCGCAGCTCCGCTTTGACTATTCCAAGCAGAAGCTGGAGCGCCTTAATTGCGATCGTGCGGGGCGCAAGTTCATACCGAATTACATCTACTACGATCAAATGAACTTCATGGACGACGACATACCGCCGTTCAAGTGCCAGCATTGTGCAGAGATTGTGCAGACGCTGCGCGAACTCGACCTGCACATGCTCACCCACCAGCCGAGCCTCGGCGGCGGCTACTATTGCAATGTGTGTAACATTCAGTTTAACAGCGCTGAGGAGTTCGATAGCCACAAGCAGCTGCATCTGGGCGCCGGCACCGAGGGCAAATTCAACTGCGAACTATGCACGGCCAGCTTCCGGGAGAAGTCCAACTACGATGAGCATTTGCGGCGCCACAACGAGGAGCTGTTCCTGCCAACGCTGGCGCTCAATCTCAATCACAGCATACTGGAGTCCTCGGGCCCCGCCgattctggttctggttcggGTTCTGGTTCGGGCGATGCTCATAagcgccgccgccgccgaagCGGTGTCCAATCGTCTGACGAAAATGCCGATGAGCAGGACGATCAGCAGGACGGACCAGCAGACGGAGAGCTGAAGCCTTTTGGGTGCGGTGTGTGCCAACGGAGCTTCGCGACGCCCGGCCACCTGAATGCCCACCGCATTGTGCATCAGGATGAGCGTGAGCGCTCCTACAAGTGCGACTATCCGCAGTGCAACAAGTCATTTATGGCCCGCAACAGCCTGTTCGAGCATCTGAAGTTGCACTACAGCAACGAGGAGTTCAAGTGCGACATCTGCGGCAAGACCTTCAAGTCCACAAAGAATCTGCAGAATCACAAACAGATCCACGACAAGGTCAAGCGTTATGTCTGCCAGATATGCGGCTCTGCATTCGCCCAGGCCGCCGGCCTCTATCTCCACAAGCGACGACACAATCGGCCCAATGGCGCTGTTGGTGCTGTTGGCCGATCGGGTCGTAGCAGCCTGTGA
Protein Sequence: MSVLAYPRTNDEEIFRHCTKDCGVVTATEDFQYFALRCIFCSEKFLYFDSFISHMQTVHLGTEGHVPPSSLALSFGEPMSLSMDEDALHEGIHHRNGHHFDEIEDLTDADTALLEPQMVIKQELPEPPCSDDDDDDDADPDHDEDVLRLPADEDDSEAIDDEEAILPESDVPAIIPRPRPRMKVTKPRVDVKNEPITADGDSSMDDYADHDRSYMGDNENDNSGEYLDYSGGSSSFNTAANHIFPGNESTDFLSYDEMVEESLLGRDRELTMHIKDRKMIQFLIQSYQRNPFLWDHSDAQFRDRVKRARFLDWIVLEFQSRFNISLAKDAITRKWDNLRTVYKRECNRMALEKTNISTLWYFKELHFLNEVYSYNSKMSDAVVKETSYRRRFSAIWNDTSTAKLLSMVKRYQCFYNRFDPDYRSKERRGEGLHQMAMELQQLIDVSTIQISKRISQLRFDYSKQKLERLNCDRAGRKFIPNYIYYDQMNFMDDDIPPFKCQHCAEIVQTLRELDLHMLTHQPSLGGGYYCNVCNIQFNSAEEFDSHKQLHLGAGTEGKFNCELCTASFREKSNYDEHLRRHNEELFLPTLALNLNHSILESSGPADSGSGSGSGSGDAHKRRRRRSGVQSSDENADEQDDQQDGPADGELKPFGCGVCQRSFATPGHLNAHRIVHQDERERSYKCDYPQCNKSFMARNSLFEHLKLHYSNEEFKCDICGKTFKSTKNLQNHKQIHDKVKRYVCQICGSAFAQAAGLYLHKRRHNRPNGAVGAVGRSGRSSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487514;
90% Identity: iTF_00601285;
80% Identity: -