Basic Information

Insect: Drosophila persimilis
Gene Symbol: -
Assembly: GCA_003286085.2
Location: NW:6358635-6360969[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.013 0.71 10.1 1.7 6 23 319 336 319 336 0.98

2 9 3.1e-05 0.0017 18.3 3.4 1 23 342 365 342 365 0.93

3 9 3.2e-05 0.0018 18.3 0.8 1 23 373 395 373 395 0.97

4 9 2.2e-05 0.0012 18.8 0.1 2 23 401 423 400 423 0.95

5 9 0.14 7.6 6.9 0.1 2 23 429 450 428 450 0.95

6 9 7.6 4.2e+02 1.4 6.9 2 23 459 480 458 480 0.91

7 9 0.00021 0.012 15.7 0.3 2 23 489 511 489 511 0.96

8 9 1.1e-05 0.0006 19.8 0.8 1 23 517 539 517 539 0.97

9 9 7.5e-05 0.0042 17.1 5.5 1 23 545 568 545 568 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.013	0.71	10.1	1.7	6	23	319	336	319	336	0.98
2	9	3.1e-05	0.0017	18.3	3.4	1	23	342	365	342	365	0.93
3	9	3.2e-05	0.0018	18.3	0.8	1	23	373	395	373	395	0.97
4	9	2.2e-05	0.0012	18.8	0.1	2	23	401	423	400	423	0.95
5	9	0.14	7.6	6.9	0.1	2	23	429	450	428	450	0.95
6	9	7.6	4.2e+02	1.4	6.9	2	23	459	480	458	480	0.91
7	9	0.00021	0.012	15.7	0.3	2	23	489	511	489	511	0.96
8	9	1.1e-05	0.0006	19.8	0.8	1	23	517	539	517	539	0.97
9	9	7.5e-05	0.0042	17.1	5.5	1	23	545	568	545	568	0.98

Sequence Information

Coding Sequence: ATGATTTGCCGATTGTGCCTAAACAGCGTCAGCGACACGGACACCATCCAGATCTTCGAGAGCATTGGCGTTACATTGAATGTGGCTACAGTGCTGGGCAAATACTTTTGGTTTGAGCCAAAAAACGATGATCCCATATCGACGGTGCTTTGCGTGGGTTGCTGGAACCAAGTGAGCCAATTCCATGAGTTCTTTGTGGCCGTGGAGAAGGCGCACCGGCTGCTCACCGAACGCTTCTCCCTCAATGTGGGGGAAAAGTCTAACAGCGTACAGCCAGAGATTGAGGAGGAGCCAAATCAGCTTCCTGATGAGGCAGAGGAGGCGCCCCAGTTGCCTGATGGGAAGGAAGAGCTAAGCCATTTACTTGATGAGCCGGAGAAGCCGCTTCCGTTGTCTGATGGGGCGGAGGAGCTGCTTTTCCAGCAGGAATTGGACGTGGGTCATCAGGACTGCGATAGCGATGCCTCCTTCAGCAATGAGCAGTTCCTTAGCCAGGTACTGTGTCCGCAGGATACTGATGACCAGCAGGCAATGGAGAAGCAAGAGGAAGTGGATTTCAAGAATGTGCCACTCATTGCTGTAGAAGAACGTCGGGAAACGCGCTCGACAGCCAGAATAAAATCGCATCAGGCAGCAAATATGGAGCTCTTAGGAGCAGACCTAGAATCCTTGGCAGCAGATGCGGAATCTCTAGAAGTCACAGACAGCGAATCCAAACCGGTGAACACTTCAGCTACCGTCGCCAAGCGACGAATGCGAAGTCGCAAGTCCGAGCAACATTCAATGAAAGCCAAACGTTACGTGGACTATAAAAAGTCCATGCTGGATATCGACCAGAAGATCGCTGGCCACATGCGTCTGACCTGCGACATCTGCCACCAGGGCCACGCGACCTTCCTGTTACTCTGCAAGCACATGCTGCAGGTGCACCACCGCAAGGGGTATGCCATCTGCTGCCACAAGAAGTTCTACAAGCGCTCCGCTCTGACGGACCACATTGACCGACACACAGATCCCGAGAAGTTCAAGTGCACGGAGTGCGACAAAACTTTTGCGGACAAGCAGTGCCTGCGCAATCACGAGCTGCTGAAGCACCAGCCGGACGATGTGAAGGTCTTCATGTGCGAGCAGTGTCCCAAGCGCTACACAAAGCAGTATTTGCTGGAACAGCATCGAATCATCCACAAGGAACGCACTATACCGTGTGGAATCTGCGACAGACGGTTTCCCAATAACTCTCTGCTCAGTACTCACGTGAAAATGGTCCACAGTAACTATGGCACAATGTGCGACATCTGCGCTCAGGTGATACGCGGAAGAGCGGCCTTTAAGCGCCATCAACTAGAACACTCCGGTGTCTCAGAGCCGAAGGTACAGTGTGACATCTGTGGATCGTGGCACAAGAACAGGCATAGCCTGAAGAAGCATGTGCGTCGGCACAAAGGATCCTCGGAAGAAGTGCGCACATGCAAGGTGTGTGGCAAGGTGTCACCCAATCGGAGCGCCATGCTGAGTCACCAGCGTTATGTGCATTTGGCGGATCGTAAGCATGAGTGCAGTGTGTGCAACAAGGCCTTCAAGAAAGCGATTACCCTCAAGGAGCACATGGCCATGCATACGGGGGAGGTGCTCTACAAGTGTCCCCACTGCCCCAAGACATTCAACTCGAATGCCAACAAGCACACCCATCGCAAGAAGGCTCATCCCAAGGAGTTCGAGGAGGCGCGCAAGGCCCGCACCGAGAGCCGAATGGCCACCGCCGTCGATGGGCCTGGGCCTGATCCTGAGACCCAGATTATCACAATCTCTACGGAAGGCGACGAGGGCGAGAGCGAAACACAAAACATTCTGCTCACCGCCACCGAGGAGGAGCTCAAGGCCGAGGGCATTGAGTTCACCCTGTGCCTTAGTCCGCAAGCGGCAGAGTGA
Protein Sequence: MICRLCLNSVSDTDTIQIFESIGVTLNVATVLGKYFWFEPKNDDPISTVLCVGCWNQVSQFHEFFVAVEKAHRLLTERFSLNVGEKSNSVQPEIEEEPNQLPDEAEEAPQLPDGKEELSHLLDEPEKPLPLSDGAEELLFQQELDVGHQDCDSDASFSNEQFLSQVLCPQDTDDQQAMEKQEEVDFKNVPLIAVEERRETRSTARIKSHQAANMELLGADLESLAADAESLEVTDSESKPVNTSATVAKRRMRSRKSEQHSMKAKRYVDYKKSMLDIDQKIAGHMRLTCDICHQGHATFLLLCKHMLQVHHRKGYAICCHKKFYKRSALTDHIDRHTDPEKFKCTECDKTFADKQCLRNHELLKHQPDDVKVFMCEQCPKRYTKQYLLEQHRIIHKERTIPCGICDRRFPNNSLLSTHVKMVHSNYGTMCDICAQVIRGRAAFKRHQLEHSGVSEPKVQCDICGSWHKNRHSLKKHVRRHKGSSEEVRTCKVCGKVSPNRSAMLSHQRYVHLADRKHECSVCNKAFKKAITLKEHMAMHTGEVLYKCPHCPKTFNSNANKHTHRKKAHPKEFEEARKARTESRMATAVDGPGPDPETQIITISTEGDEGESETQNILLTATEEELKAEGIEFTLCLSPQAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00564158;
90% Identity: iTF_00487505;
80% Identity: iTF_00581009;