Basic Information

Insect: Drosophila persimilis
Gene Symbol: -
Assembly: GCA_003286085.2
Location: NW:8026085-8030502[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0034 0.19 11.9 0.8 1 23 189 211 189 211 0.98

2 7 0.0055 0.31 11.3 4.5 1 23 543 565 543 565 0.96

3 7 7e-05 0.0039 17.2 3.1 1 23 571 593 571 593 0.98

4 7 3.1e-05 0.0018 18.3 0.6 1 23 599 622 599 622 0.96

5 7 2.3e-06 0.00013 21.9 2.9 1 23 628 650 628 650 0.97

6 7 6.3e-06 0.00035 20.5 0.7 1 23 656 678 656 678 0.97

7 7 1.7e-05 0.00094 19.2 2.3 1 23 684 706 684 706 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0034	0.19	11.9	0.8	1	23	189	211	189	211	0.98
2	7	0.0055	0.31	11.3	4.5	1	23	543	565	543	565	0.96
3	7	7e-05	0.0039	17.2	3.1	1	23	571	593	571	593	0.98
4	7	3.1e-05	0.0018	18.3	0.6	1	23	599	622	599	622	0.96
5	7	2.3e-06	0.00013	21.9	2.9	1	23	628	650	628	650	0.97
6	7	6.3e-06	0.00035	20.5	0.7	1	23	656	678	656	678	0.97
7	7	1.7e-05	0.00094	19.2	2.3	1	23	684	706	684	706	0.97

Sequence Information

Coding Sequence: ATGGAGCGCAAAGAAGTGGACGCACAGCAGTTCATTGATCACACGCTGCTGGCCTCGGAGCTAATGCGGGATCCAAATCACTTTATTATGGATCTGATCGATCACACAGGAGTGTTCCCCAAGGCCGAGGGACCCACCAATCTGACCACCAACACGGGAAATCCCCCCAATGATGGGACTGGCGGCTACGCGGAGAAGGAGCTGAACTTCCACAACACAATCTTCCAGTTGGTGAACAAGCATGTGAACGAATCCTCCGCCGCGGACAGCGGTGTGGGGCCGGTGGTGTCGCAGCAagtgcagcagccagcatTCCCAGCCCTGGCCATAGAACCGACCGTACCCATCGATGTCTCGGCGTGTCTGCACGCTGTCGACGATGACGATCTTCTGTATGTCCATAATGCTCTAACGACCAATGCCCGCAAGGTGCTGCCCCACAAGAAGCGCATCTCGAGGAAGCTCAAGGGCAACATCGATGCCGAgatggagcagcagcaccagccgcaccaccagcagcacaaGCATGTCATTCAGCATGTCCCACCAGGAGCGGCTTCGCTCTACAGCTGTGAGATCTGCGGCTATGCAGTGCACACACAGTTGGACTTTTTTGCCCATCTCAAGCAGCATTATGAGCCACCAATGGCCATGGAACAGCGATTGGAAGTGCCGatccaacaacagcagcagcagcagcagcaagaacaGCAGAAGGAGCCGTTGGACATGTGCGGTCTCTCCACACAGGATAAGCTTCAACAGGAACAGGCCAAACTGGATCAGGTCTTTCACGATGTTCAGCTGAACTTTGAGAACTTTCACCCCATCAGCCATGTGGATCACGATGTGGGAGTGCCTGTAAATGTAAATGATGTTGGCGTCAATATGGTCATGCATGGCGAAGCCACAGACAAACTGAATACCGTGGGAGCCACCAGCAGCTCGCCCAACGTCAACGTCGTGGTCCCCGTCGTGGATGATGTGGAGTTCAGTGACACGGAGGACATGCTAGAGGGCATACGGAACGTAGTGGATAAGGTGTCCATCGAGGACACTTGCGATGAGCTGGTGGAACTGGAGCTAACCACAGCCACGATCCGGGCGCCCTGGTTTAACAACAACTTCAGTGACATCACATTTccggggctgctgctgccgggaGAGCCGCCGCCAGCGACCACGGAGCAAGCGGCGACGCCGCTGCTCAAAGAGAATCCCAATGGGACGGAACAGATGGATTTGGATTTCCTCAGTGCCAGCAAACGAGAGGaatcaaatgaaatcaaaATGGAGAAGGCGCTGGAAAAACCCATCGAAGGGATTGAACAGCCCCTGCTGGTGGCGCCACCAATGTGCTGTACCTCTCCGGCACCGCCTGCTGCCCCGCCGCCCGGCTCGACCGGCTCGCCGCTAGTCCTAAACGAAGCCGGCTTCAAGCTGGAGGCCGTGGAAATGCCCGACGACAGCGCACCACCTTCACCATTCGACAATGGCGACGTaggcggcgacggcgatggcgatggcgatggcgacggcgagGATGAAGACAATACCGATAGCTATGCCATGGAAAGCACCGCCACGAGTCCGAGCGAGGACTCGCCGAGCAAATCGAGGAGGAAGCACTTTTGCGACAAGTGCAACAGGGACTTCAATTCGTACAATGCCCTCAAATACCATCAATATACACACAACCAGGAGCGCTCGCACAAGTGCAGAAGCTGTGAAAGATCCTTCTACAACCAGAGTGCGCTGACGGCCCACGAGAAAACGCACTCTGGGATAAAGCCCTTCGAGTGCGAGAAATGCGACTCCAAGTTCCGACAGTGGGGTGATCTCAAGTACCACATCATATCCAGACACAGCGACATCAAGGCGCACATGTGCGAGTTCTGCGGCAAGAGCTTTTCCCGACGGTACTCTCTGGTCCTGCATCGACGGATCCACACCAGCGAGCGGAACTACGCCTGCCAGTACTGCGACAAAACGTTTCGGGCCAGCTCGTACCTTCTCAGCCACGTCAAGGTGCACACGGGAGAGCGACCGCACGAGTGCAGCGTATGCCAGAAGAAGTTTCGCGTCTCGGGGGATCTCAAGCGGCACTCGCGTATACACGATCCGGCCAGAAAGAGCCAACCTCCGGCCGCAAAGGTGGAGAAAAAAAAGCTGAAGCAAATCAAAGATGAGGAGGaggtggtggcggcggcggcggcggtggttgCCACCCATAAACAAAAGTCTGACGCCCTATGCGACGAATCTGAGCAGGAAATTCTCGGCCTATAG
Protein Sequence: MERKEVDAQQFIDHTLLASELMRDPNHFIMDLIDHTGVFPKAEGPTNLTTNTGNPPNDGTGGYAEKELNFHNTIFQLVNKHVNESSAADSGVGPVVSQQVQQPAFPALAIEPTVPIDVSACLHAVDDDDLLYVHNALTTNARKVLPHKKRISRKLKGNIDAEMEQQHQPHHQQHKHVIQHVPPGAASLYSCEICGYAVHTQLDFFAHLKQHYEPPMAMEQRLEVPIQQQQQQQQQEQQKEPLDMCGLSTQDKLQQEQAKLDQVFHDVQLNFENFHPISHVDHDVGVPVNVNDVGVNMVMHGEATDKLNTVGATSSSPNVNVVVPVVDDVEFSDTEDMLEGIRNVVDKVSIEDTCDELVELELTTATIRAPWFNNNFSDITFPGLLLPGEPPPATTEQAATPLLKENPNGTEQMDLDFLSASKREESNEIKMEKALEKPIEGIEQPLLVAPPMCCTSPAPPAAPPPGSTGSPLVLNEAGFKLEAVEMPDDSAPPSPFDNGDVGGDGDGDGDGDGEDEDNTDSYAMESTATSPSEDSPSKSRRKHFCDKCNRDFNSYNALKYHQYTHNQERSHKCRSCERSFYNQSALTAHEKTHSGIKPFECEKCDSKFRQWGDLKYHIISRHSDIKAHMCEFCGKSFSRRYSLVLHRRIHTSERNYACQYCDKTFRASSYLLSHVKVHTGERPHECSVCQKKFRVSGDLKRHSRIHDPARKSQPPAAKVEKKKLKQIKDEEEVVAAAAAVVATHKQKSDALCDESEQEILGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517930;
90% Identity: iTF_00474008;
80% Identity: -