Basic Information

Insect: Drosophila persimilis
Gene Symbol: -
Assembly: GCA_003286085.2
Location: NW:652359-655632[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.32 18 5.7 0.1 3 23 305 326 304 326 0.91

2 10 7e-05 0.0039 17.2 0.5 6 23 335 352 335 352 0.99

3 10 1.8e-05 0.001 19.1 0.3 1 23 358 381 358 381 0.98

4 10 0.00015 0.0086 16.2 0.7 1 23 393 415 393 415 0.97

5 10 0.0011 0.059 13.5 7.1 1 23 422 445 422 445 0.96

6 10 3.7e-06 0.00021 21.2 2.4 1 23 451 473 451 473 0.97

7 10 0.07 3.9 7.8 0.7 2 23 482 503 481 503 0.97

8 10 0.00013 0.0072 16.4 2.7 3 23 510 531 508 531 0.95

9 10 1.4e-06 7.8e-05 22.6 1.1 1 23 537 559 537 559 0.98

10 10 0.00019 0.011 15.9 4.4 1 23 565 588 565 588 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.32	18	5.7	0.1	3	23	305	326	304	326	0.91
2	10	7e-05	0.0039	17.2	0.5	6	23	335	352	335	352	0.99
3	10	1.8e-05	0.001	19.1	0.3	1	23	358	381	358	381	0.98
4	10	0.00015	0.0086	16.2	0.7	1	23	393	415	393	415	0.97
5	10	0.0011	0.059	13.5	7.1	1	23	422	445	422	445	0.96
6	10	3.7e-06	0.00021	21.2	2.4	1	23	451	473	451	473	0.97
7	10	0.07	3.9	7.8	0.7	2	23	482	503	481	503	0.97
8	10	0.00013	0.0072	16.4	2.7	3	23	510	531	508	531	0.95
9	10	1.4e-06	7.8e-05	22.6	1.1	1	23	537	559	537	559	0.98
10	10	0.00019	0.011	15.9	4.4	1	23	565	588	565	588	0.96

Sequence Information

Coding Sequence: ATGACTGCCTGCATGAACTATCGATTGCGCACAGTCATAGCTATCGATCTGCACGCAAAGATGATTTGCAGACTATGCCTGCGCACCATAAATCCCAGCAATGCCGTATTCCTGTTCGAAACGAACGAGACGTTGGCGGAAACTACTCTGGTCAAGATGATTGCCAAATTCCTGCAGTTGGAGATCACGCCCGATGACAGTATCTCGACGAGTGTCTGTACCGAGTGCTGTGAGCATCTGGAGGATTTCAATACCTTCTGGCAGCTGGTGGAACAGAAGCAGGGCACCCTCAAAAAGGAGTTCCTCACCGTCGACGTGGACTGTGTGGCGATGAAGTGGACGGGCGAGGTAGATGTGGACGTCAACATTGACGAGCTGCCGCTGGTGGCAGTCGAAATGGACGAGAAGCCCCTCGATATGCACAACCTCAGCCTGCTGGGCAGTGTTCTGGATGTGAATGTGGACAGTGTCGAGGTGCCACAGGCGCCGCCTGGCGATATCAAAATTCAGCCGACTGATTACTTGTCCGAGGAAGACGGGCATCCTTCTCATATCGAGGCGACGGACAGCGAGTTCGAATGCGAACCGGTCCCCGAAGAAAACACCTCGGATGATGAGCCGCTGGTCAAGCTGCAGGACAAGCTGAAGCCAAAGCGCAGGTCCCACCCCCGCACCACAAAGACACGGGAAGACACCTGCTCACTCGGAGCTCAGGAGCTGAATTATCTTCTTGGGCGGGGTGATGGCGAGGGCAGCAAAGGGCGTCGCAGAAAGGCGCCTGGCCAGCGCATACCCACGGAAGTGCAGGAGAGCGAGCTGCAGGCAGCGCTCGAGCGCAAGCCCAAGGGCTGCTCGCGGGCACAGCTGGCCAAGCGGTACGAGGAAGTCATTGCCAGCTACATGAACGCCGACTGCGACCTGTGCGAGTTCAGCGGCAAGTATCTGTCCGAGCTGAAGGTGCACTTCCTGGAGGCCCACCAGCGTGAGTTCTACATCAAGTGCTGCAATAAGGTTTTCACACGCGCTTCCAAGCTGATGGACCACATTCGCAAGCACGTCAATCCCAAGCTCTTCACCTGCTCCATCTGCCAGAAGACTCTCAATTCTCAGGACTATCTGGCCACCCACATCGAGACGGTGCACAACAAGGTGGAGAAACTCGACAAGGTGCTGCAGTTCCCCTGCTCCAAGTGCGAGCGCACCTTCAGCAGTGAGCGACGCCTGGCCAACCATCTCGCGAAGCACGACACGGCGACGCTGGAGCACATCTGCCACATATGCCATAAAAACTTTGCCAATGTCCATCGGCTGCGCCGGCACATCCAGTCCATACACGAGGACCTGCACCGACATGTGTGCGACATCTGCGGCAAAAAGTTCAAGTTCAAGCCTTCATTCGAGCGGCATCTGCGCGAGCATCAGGGCGTAGTTGCACCGGCCATGCAATGCCCCGTCTGCGGTGTTTGGCTGAAGAACGAGCACAGTCTGCGGCTGCACCGCTTCACCCACGACAGCACCAACACGGCCTGTCCCCATTGCTCGAAGACCTGTAACTCGAGAACAGCGCTACGCGCTCACATCAAGTATGCCCACAAGCTGACGACCAGCTTCCAGTGCACGTACTGCGAGAAGACCTTCAAGCAGCAGCGCAACCTGGACGAGCATCTGGCCATCCACACGGGCCTCCAGCTGTACAACTGTCCGCACTGCCCCAAGGAGTGCCGCTCTCGGTCCAACATGTACGTGCACATCAAGCAGCGACATGCGGAGGAGTGGCTCACCGCCAAGATGGCCCGCTCCCACAATCCGCAGTTCAAGCCACACGCCTAA
Protein Sequence: MTACMNYRLRTVIAIDLHAKMICRLCLRTINPSNAVFLFETNETLAETTLVKMIAKFLQLEITPDDSISTSVCTECCEHLEDFNTFWQLVEQKQGTLKKEFLTVDVDCVAMKWTGEVDVDVNIDELPLVAVEMDEKPLDMHNLSLLGSVLDVNVDSVEVPQAPPGDIKIQPTDYLSEEDGHPSHIEATDSEFECEPVPEENTSDDEPLVKLQDKLKPKRRSHPRTTKTREDTCSLGAQELNYLLGRGDGEGSKGRRRKAPGQRIPTEVQESELQAALERKPKGCSRAQLAKRYEEVIASYMNADCDLCEFSGKYLSELKVHFLEAHQREFYIKCCNKVFTRASKLMDHIRKHVNPKLFTCSICQKTLNSQDYLATHIETVHNKVEKLDKVLQFPCSKCERTFSSERRLANHLAKHDTATLEHICHICHKNFANVHRLRRHIQSIHEDLHRHVCDICGKKFKFKPSFERHLREHQGVVAPAMQCPVCGVWLKNEHSLRLHRFTHDSTNTACPHCSKTCNSRTALRAHIKYAHKLTTSFQCTYCEKTFKQQRNLDEHLAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHAEEWLTAKMARSHNPQFKPHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00474705;
90% Identity: iTF_00580951;
80% Identity: -