Basic Information

Insect: Drosophila persimilis
Gene Symbol: Zfy1
Assembly: GCA_003286085.2
Location: NW:28310348-28312876[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 1.9e-06 0.00011 22.1 0.3 1 23 289 311 289 311 0.98

2 10 8e-07 4.5e-05 23.3 3.4 1 23 317 339 317 339 0.97

3 10 0.0016 0.09 12.9 2.8 2 23 392 415 391 415 0.90

4 10 7.2e-05 0.004 17.2 3.5 1 23 415 437 415 437 0.97

5 10 0.0082 0.46 10.7 0.7 1 23 468 490 468 490 0.96

6 10 2.9e-07 1.6e-05 24.7 2.0 2 23 571 592 571 592 0.98

7 10 2.1e-05 0.0012 18.8 1.0 1 23 598 620 598 620 0.98

8 10 3e-05 0.0017 18.4 1.1 1 23 626 648 626 648 0.98

9 10 1.8e-06 0.0001 22.2 1.3 1 23 654 676 654 676 0.98

10 10 7.8 4.4e+02 1.3 0.0 8 19 690 701 682 703 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	1.9e-06	0.00011	22.1	0.3	1	23	289	311	289	311	0.98
2	10	8e-07	4.5e-05	23.3	3.4	1	23	317	339	317	339	0.97
3	10	0.0016	0.09	12.9	2.8	2	23	392	415	391	415	0.90
4	10	7.2e-05	0.004	17.2	3.5	1	23	415	437	415	437	0.97
5	10	0.0082	0.46	10.7	0.7	1	23	468	490	468	490	0.96
6	10	2.9e-07	1.6e-05	24.7	2.0	2	23	571	592	571	592	0.98
7	10	2.1e-05	0.0012	18.8	1.0	1	23	598	620	598	620	0.98
8	10	3e-05	0.0017	18.4	1.1	1	23	626	648	626	648	0.98
9	10	1.8e-06	0.0001	22.2	1.3	1	23	654	676	654	676	0.98
10	10	7.8	4.4e+02	1.3	0.0	8	19	690	701	682	703	0.86

Sequence Information

Coding Sequence: ATGGCGAAGGTGTGCCGGGTGTGCCTGGATGATTCCGTTCTACTGGTAGATATATTCGCTGAAGTCTGCAATCTCTGGGAGCTGCCTGAAAATAGCCCTGCCTACGTCATAAGCCAGTTCTCACCTGAGAATTCTGTGGAGCGCGGGGACTCTATGCCGCAGCTTATATGCCACTCCTGCATTAATGGGGTCCAGAGTGCATATCGTTATAAGCTAAAATTGGACCAAGGATCTGAAAATTATCAACGTTTTCTAAAGAAAACGCAGCAGAAACGTTTTCATACAGTTTTATCAAGCGTTTCGGAAAATAATGAAACGTACACAATTAATATCAGCGATAAAGAGGAGAATCTCATTCGTGCAAATGAAAGCCATGGGATCAAGGCAGAGCACGAGATTGTTCTGCTGCCCGTGAAGACGGAGGTGGTGGAGCACAACGCTTACGACGAGGCTCACATGTGTATTAGTCTGCAGGAAGACATTGCCAATTTTGACATTGACATTGAGGAAGGCACTTACACAGTAAGGAACCCTCGTTGGGACTACGTGGATGAACAGGCTGGCCTGAAGATGAGTGTTTCAATGGATACACCTGATATTCACAAAATAGAGCATGTGCCCGAGCTAGCTCAGGTGGCAGAATCGAAACTTAACAATCTGAAATTAGAGCACGCTTTGAGAGAAAATGAGGTTCACATaagaaaaaatatacaatCGAACAAAGAGAATAAGAGGCAGGAGTCAGAGAAAAATAACCATCCATTAGAAAAAGAGGATTCCttggagacgatggaaatTCGTATGAGTATATCAACGGATACCGAGAACCAAGAAACTGATGACAGGGCGAAGTTGGTCAAACTGTATGAGTGCAAGTGGTGCGGCAAGGTAGTCTCGCGCAGCCAAAATTTAAGATGGCATGAAATGCGTCACTTTGGCAAGTTTCCGTTCATTTGTGATGTTTGTGGCAAAGGATTTAGAACTAAGTACCACCTGAAAAGACATACCACCAGTCACAAGAACAATCAGACGGCGGAAATAAGCAAAATGAAGCCTCTTGGAAAAAAGAGCACGTATCGTAGTCCGTCGCAGAAAAAGAAGACCCTAGAAGACCACAACAATGATCGTCTGGAAAGCATTTCTTCCAGAAAAATTCGTAGTACCGCAGAACTTCCATGTCCGCAATGCTATAAATGTTTTGACTCACAGTTTAAGCTCGAATATCACATTAATAAGACGTGCCATAAGTGTCCCCACTGCTCACGCTTTTATGCAAATGAACGTAGTCTAAGGAGACATCAACAAGAGCACATTCCACTGGCAGCCTTTGAGGGCCCGCGATCATTCTCGAACATGAATGAGCTGAGGGAGCCGCGTGTCAAGCACAGCGACAATGGCCTGTTTAAGTGCCAAGAATGCCATGCAGTATTCATCGACATCCTTTATCTGCAGATCCACAGTAAAGAGCATGCTGGTGAACAAGGGCAACTGGAGCGTAGCCGAGGAGCCACACTCCCTAGGGCTAAGAAACAGGTCGACTCCGACTCGAAGAAGAGTGTTTTAGAAATGTTTTCCTGCCATGACGCTAATGGTCGCTCAAAAAATCCAACAATGCTAAAGAAGCTGAAGCTCACCGACCCCGACCCTGCTATATCAAGCCCCACAAAGAAGAGCTGGATGACCCAATCCTTGCCAATAAAACTGGAAAATACATGCCAGCAGTGCGGTAAGAAATTTACCTATAAACAAGCCCTGACTAGGCACATGCGTGTTCACACTGGCGAGCGTCCTTTTGAATGCACGTATTGCGAGAAGAAATATTCGCGCAAGGCTCAGCTAGATGAGCACACTGCTACCCACACTGGCGACCGTCCTTTCGAGTGCTTGGTTTGCGAGAAGAAATTTATTCGCAAGATACACCTAGCTGAGCACACTCGTATTCACACTGGCGACCGTCCTTACGAGTGCTTGACTTGCGGCAAGACTTTTCCACGCAAGTATACCCTGCTTAAGCACAATCGTATCCACACTGGCGGTCACCCTTCCGATTGCCCCAAGAAGAAGGAAAAAAGCTTTGACGATAGCTATAAACTGGAGATACACGAAGGAAAGGCGTCGAATAACAACAATATGCCTGAACAGCGTTTGGACATTAAGGATGAAATCGCTTGA
Protein Sequence: MAKVCRVCLDDSVLLVDIFAEVCNLWELPENSPAYVISQFSPENSVERGDSMPQLICHSCINGVQSAYRYKLKLDQGSENYQRFLKKTQQKRFHTVLSSVSENNETYTINISDKEENLIRANESHGIKAEHEIVLLPVKTEVVEHNAYDEAHMCISLQEDIANFDIDIEEGTYTVRNPRWDYVDEQAGLKMSVSMDTPDIHKIEHVPELAQVAESKLNNLKLEHALRENEVHIRKNIQSNKENKRQESEKNNHPLEKEDSLETMEIRMSISTDTENQETDDRAKLVKLYECKWCGKVVSRSQNLRWHEMRHFGKFPFICDVCGKGFRTKYHLKRHTTSHKNNQTAEISKMKPLGKKSTYRSPSQKKKTLEDHNNDRLESISSRKIRSTAELPCPQCYKCFDSQFKLEYHINKTCHKCPHCSRFYANERSLRRHQQEHIPLAAFEGPRSFSNMNELREPRVKHSDNGLFKCQECHAVFIDILYLQIHSKEHAGEQGQLERSRGATLPRAKKQVDSDSKKSVLEMFSCHDANGRSKNPTMLKKLKLTDPDPAISSPTKKSWMTQSLPIKLENTCQQCGKKFTYKQALTRHMRVHTGERPFECTYCEKKYSRKAQLDEHTATHTGDRPFECLVCEKKFIRKIHLAEHTRIHTGDRPYECLTCGKTFPRKYTLLKHNRIHTGGHPSDCPKKKEKSFDDSYKLEIHEGKASNNNNMPEQRLDIKDEIA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00580917;
90% Identity: iTF_00580917;
80% Identity: -