Basic Information

Insect: Drosophila persimilis
Gene Symbol: Paris
Assembly: GCA_003286085.2
Location: NW:1929353-1931286[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 9.5e-07 5.3e-05 23.1 9.0 1 23 126 148 126 148 0.99

2 15 4.9e-05 0.0027 17.7 11.1 1 23 154 176 154 176 0.98

3 15 6.4e-05 0.0036 17.3 3.2 2 23 183 204 182 204 0.97

4 15 1.1e-05 0.00065 19.7 0.8 1 23 210 232 210 232 0.99

5 15 0.0012 0.067 13.3 7.0 1 23 238 260 238 260 0.98

6 15 9.2e-09 5.2e-07 29.4 0.7 1 23 266 288 266 288 0.99

7 15 2e-07 1.1e-05 25.2 5.1 1 23 294 316 294 316 0.98

8 15 3.8e-07 2.1e-05 24.4 1.8 1 23 322 345 322 345 0.98

9 15 5.7e-07 3.2e-05 23.8 8.4 1 23 351 373 351 373 0.98

10 15 2.9e-07 1.6e-05 24.7 3.0 1 23 379 401 379 401 0.99

11 15 0.00021 0.012 15.7 1.7 1 23 407 429 407 429 0.98

12 15 1.1e-06 6.2e-05 22.9 1.0 1 23 435 457 435 457 0.99

13 15 9.2e-07 5.2e-05 23.1 9.7 1 23 461 483 461 483 0.99

14 15 2.1e-06 0.00012 22.0 3.3 1 23 489 511 489 511 0.98

15 15 0.11 6.1 7.2 7.7 1 23 517 540 517 540 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	9.5e-07	5.3e-05	23.1	9.0	1	23	126	148	126	148	0.99
2	15	4.9e-05	0.0027	17.7	11.1	1	23	154	176	154	176	0.98
3	15	6.4e-05	0.0036	17.3	3.2	2	23	183	204	182	204	0.97
4	15	1.1e-05	0.00065	19.7	0.8	1	23	210	232	210	232	0.99
5	15	0.0012	0.067	13.3	7.0	1	23	238	260	238	260	0.98
6	15	9.2e-09	5.2e-07	29.4	0.7	1	23	266	288	266	288	0.99
7	15	2e-07	1.1e-05	25.2	5.1	1	23	294	316	294	316	0.98
8	15	3.8e-07	2.1e-05	24.4	1.8	1	23	322	345	322	345	0.98
9	15	5.7e-07	3.2e-05	23.8	8.4	1	23	351	373	351	373	0.98
10	15	2.9e-07	1.6e-05	24.7	3.0	1	23	379	401	379	401	0.99
11	15	0.00021	0.012	15.7	1.7	1	23	407	429	407	429	0.98
12	15	1.1e-06	6.2e-05	22.9	1.0	1	23	435	457	435	457	0.99
13	15	9.2e-07	5.2e-05	23.1	9.7	1	23	461	483	461	483	0.99
14	15	2.1e-06	0.00012	22.0	3.3	1	23	489	511	489	511	0.98
15	15	0.11	6.1	7.2	7.7	1	23	517	540	517	540	0.83

Sequence Information

Coding Sequence: ATGGAGGAGATGTGCAGAGTTTGCATGGTCAAATCCGGAGCACTCGCAAACATTTTTGATGAGACACAAAAATGGGACACTTGCATTGCTGACATGATAGCCCAGTGTACCGGTTACGTGGTTAGGCGAGGGGATTCACTGCCAGAAAAAATATGCCCGCCTTGCCTTGAGGATGCAGTGAGTGCATTCAATCTTAAGAAATCCTGCGAGCAGAGCCATCGACTATATTTTCCAGTGATGGAAGAGGATGTGAAAACAGATCTCTGTGATAATTTTGAACAGAACGACTGGAACATGTCAATAAGCAGAAAAAAAGCGACGATTTTGGAAACTGATGAAAAAATATGTAAAGGTGATAAGGATGTGGATCTTCTGTTTAAGTGTACTCACTGCTCGAAGTCTTTTAAACGGAAATGCAATTTGCAAAATCACATCCGTATGCACACGGACAAACAATCCTACCAATGCTGTCACTGTTCAAAGTCGTTTAATCGAAAATCAAGTCTTCAAAGTCACATGTGTTATCACACGGAGGAGCGACACAACAAATGTGTCCACTGCTCAAAGTCATTCGTAACCATGAGCGCACTGAAGCGGCACTTTCTTACTCATATCGACGGACAACCCTACAAGTGCTCCGACTGCTTAAACTCCTTTAAAACTGAAAACGAACTCAAAGAACACATCCGTGTTCACACAGTGGAAGAGCCCTaccaatgcccccactgctCAAAGTCATTTAAGCTAAAATCGATTCTCCAAAGACACTGTCGTACCCACACTGCGGAGAGAGCTTATAAGTGTTCTGACTGCTCAAAGTCCTTTATTACTCAAAGCGAACTCAAAGTACACATCCGGGTTCACACAGGGGAACAGCCCTACCAATGTCAGCACTGCCCAAAGTCATTTCAGCGAAAATCTAATCTTAAAAGACATAATCGTATCCACACGGGGGAGAGACCTTACAAGTGTTCCGACTGCTCCAAGTGTTTTTCCATCGCCACAAATCTCCAGGCTCATATCCGTCGATGGCACACAACTGACCGACCCCACAAGTGCACTCACTGCCCGAAGTCGTTTACAGAAAAATCTCATCTCCAGATACACATGCGTAAACACACGGGGGAGCGACCGTACAAGTGTACCCAATGCTCAAAGTCCTTTACTCGAACCGGATCTCTCCGGCGACATATCAGTACGCACACGGATGAACGACCCTACAAATGCACCGACTGTTCAACGCTGTTTCAACAAATATCCCAACTTCAAAAACACACCCTTATGCATACCGGCGAACGACCGTACAAATGCAGTGACTGCTCACAGTCCTTTCTACAAAAATCCCAACTTGAGGCACACATCCGTACTCACACGCGACCTTACAAATGCTCCCACTGCTCGAAATGCTTTAGAGAAAAATCCAATCTTAAAAGACATACCCGTACGCATACGGATGAACGACCCCACCAATGCTCACAATGCTCGAAATCATTTCAAGAAAAATCGAATCTCCAAGTGCACATACGTTCTCACACAGGGGAGCGCCCATTCAAGTGTACCCACTGCTCAAAGACATTTAGATATAAAAATAATAGCTACCAGAGACACGTAATTACTCACACAAGGAGTGACAAGTATGCCATTCCGGCACTTTTCGAGATCACTTCCATAAGAACACTGAAAATGGAAGGTGTAGAATAA
Protein Sequence: MEEMCRVCMVKSGALANIFDETQKWDTCIADMIAQCTGYVVRRGDSLPEKICPPCLEDAVSAFNLKKSCEQSHRLYFPVMEEDVKTDLCDNFEQNDWNMSISRKKATILETDEKICKGDKDVDLLFKCTHCSKSFKRKCNLQNHIRMHTDKQSYQCCHCSKSFNRKSSLQSHMCYHTEERHNKCVHCSKSFVTMSALKRHFLTHIDGQPYKCSDCLNSFKTENELKEHIRVHTVEEPYQCPHCSKSFKLKSILQRHCRTHTAERAYKCSDCSKSFITQSELKVHIRVHTGEQPYQCQHCPKSFQRKSNLKRHNRIHTGERPYKCSDCSKCFSIATNLQAHIRRWHTTDRPHKCTHCPKSFTEKSHLQIHMRKHTGERPYKCTQCSKSFTRTGSLRRHISTHTDERPYKCTDCSTLFQQISQLQKHTLMHTGERPYKCSDCSQSFLQKSQLEAHIRTHTRPYKCSHCSKCFREKSNLKRHTRTHTDERPHQCSQCSKSFQEKSNLQVHIRSHTGERPFKCTHCSKTFRYKNNSYQRHVITHTRSDKYAIPALFEITSIRTLKMEGVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -