Basic Information

Insect: Drosophila percnosoma
Gene Symbol: ken1
Assembly: GCA_035043855.1
Location: JAWNMQ010000228.1:636839-639229[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.07 4.6 7.9 5.9 3 23 253 273 251 273 0.96

2 12 0.00056 0.037 14.5 0.6 1 23 279 304 279 304 0.95

3 12 0.002 0.13 12.8 1.2 1 23 311 336 311 336 0.93

4 12 0.00098 0.064 13.7 4.0 1 23 346 368 346 368 0.97

5 12 0.002 0.13 12.8 2.2 1 23 375 397 375 397 0.97

6 12 0.0076 0.5 10.9 0.5 1 23 403 425 403 425 0.97

7 12 0.055 3.6 8.2 2.6 1 23 431 454 431 454 0.97

8 12 0.02 1.3 9.6 4.1 1 23 460 482 460 482 0.95

9 12 0.0097 0.63 10.6 2.3 2 23 489 510 488 510 0.96

10 12 0.00019 0.013 16.0 0.8 1 23 599 622 599 622 0.95

11 12 0.00039 0.025 15.0 0.8 1 23 628 650 628 650 0.95

12 12 1e-05 0.00068 20.0 2.3 1 23 656 678 656 678 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.07	4.6	7.9	5.9	3	23	253	273	251	273	0.96
2	12	0.00056	0.037	14.5	0.6	1	23	279	304	279	304	0.95
3	12	0.002	0.13	12.8	1.2	1	23	311	336	311	336	0.93
4	12	0.00098	0.064	13.7	4.0	1	23	346	368	346	368	0.97
5	12	0.002	0.13	12.8	2.2	1	23	375	397	375	397	0.97
6	12	0.0076	0.5	10.9	0.5	1	23	403	425	403	425	0.97
7	12	0.055	3.6	8.2	2.6	1	23	431	454	431	454	0.97
8	12	0.02	1.3	9.6	4.1	1	23	460	482	460	482	0.95
9	12	0.0097	0.63	10.6	2.3	2	23	489	510	488	510	0.96
10	12	0.00019	0.013	16.0	0.8	1	23	599	622	599	622	0.95
11	12	0.00039	0.025	15.0	0.8	1	23	628	650	628	650	0.95
12	12	1e-05	0.00068	20.0	2.3	1	23	656	678	656	678	0.98

Sequence Information

Coding Sequence: atgaatgaGGGGAGTGAATACTCCATTCACTCAATATGCCGAATCTGCTTAGATCACCTTCGAGATGATCCGGCGTACGACCTGTTTCTCGTTCCGGGTCTGGCcaaaaaattgtgtgtgtgtacttccCTCTCAGTGGAACAGCACGATGGCTTCCCGAAAAACCTTTGCACCAATTGCTACACCAAGCTGAACGACTTGCACGGATTCCAGAAGCTGTGCGTGGACTCTGTGCAGAAGTTTCAAGAAATGGTCGCTAGCAATTATTTTACACCTGTTATTGCcgatattaatcaaattgacAATGTCGACATACTGCATGTTCCAGCGCACGATGGGGATATGGAAGAGGATCGCATCAACTTTGATCCGCTGCTAAATACGAAAATTGAGATAATTGAGAATGAAGAAGAGGTTTTCAAAATGCTTGAGGATGTGGACAAAGAAGCGGAGGAAGTAGAAAAAGAGGAGTCGTCTAGTGAAACTGACcacgataatgatgatgatgttgattttGAAGCAAATAGCAGTGAATCTGACGACGCCATGCCCCTGTCTCGTTTACGAAGCACTACCAGAGCATCAAAGACTAAGGCTAAGAAGAGCACCCCGGATGATTTTGACGATGAATCTTCTAGCTCTGATTCGGATGACGatgaaaatgatgatgatgatgatgacgacgacaagCCCAGAACGAAACCAAAACGCAAACGCATTCCGGCAGCTGAGAGGCACTTGCATCGCCTTATCGATTGTCACATTTGCCACCAGAAATTCAAGAAGGCAATTCGCTACGAGGAGCACATGAAGCATCATAACGATCTATTGCCATTCCAGTGCAAAGTGGAAACCTGCAGGAAGGGTTTCACTACGGCTGGTGGTCTGCGCCTCCATATGGACCACGCCCATTCAGAATTCTCTGAAGTGCACGCCTGCACGTTTGAGGGATGTGACAAGACCTTCCCTCGATCAGTTTTACTCACGTTCCATATGAAAAAGGTGCACAAAGTGGCCAAGGCTGACACCCGTAATCATCCGTGCACGGAATGCGAAAAAGTCTTCCGTTGTCCAACGGCACTTAAAAAACACATGTATAAGCACACTGGCGAAGAGCTGCCTTTTGCATGCGAAATCTGTGGCAAAAGGTTCCACATCCACAGTGTGCTTAGAGACCATCTCTTGCGCCATGCCGGCGTAAAGAATCATGTGTGCCCCTACTGTGGCGTCGGTAAAACCACTCGCCAGGAGTGGAACAAACACATACTGACGCACACCAAGGAGAAGCAGTTCCAGTGTCGCCAGTGCGATCATGCTTCCCACAACAAACAGGCTTTGTCCAATCACGTTAAGGTGGTTCATATGAAGATCAAGAACTTTGCGTGTCAATATTGCGGCAAGACCTTTGGAAAATCGCATGCCTGCAAGATCCACGAAAGACTCCACACGGGCGAAAACTGCTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTCTTTGAAAAGAGATTAACCAAGCATTTGCAGATCCATGAGAAACGTGAAGCAGTTCCGCCTGCAACCGTTGTTAAGCCGCAGGAGGAAGGAGATGCTCAAAACACGCAGAATGTGAACCAGGAGTTGAATGAGCCAGTAGACGTTAAGCCAGTGCCAATAATTCCTCCTAAACCGAAGAATTCTCATCGAGTTGAGCGTGTGGATATATCGCAGCTAGCTGGCACCTCTGTTAATCCAATATCATCAGTATCGGTGCCGTCCTGGGCGCCACAAGTGAACTTCACAAAGAAGGAAGGCCAGCACATTTGTCCAGGATGTGGTCGTGGCTTCAACCACATCGGCAATATGAAACTTCACTACAAGATAATACACGAGAAGGTGAAGGACTTTGCGTGTCGCTATTGTCCAAAGCGCTTCGCCAAGGCGCAGTATCTGCGCAATCATGAATATATCCATACGGGCGAGAAGCCGTTCGAATGCAAGATTTGTGGCAAGCATTTCCGTCAGGAGCAGGTATTGAAGACGCATTTGAAGGTGCATGATAAGCCGCCGAAACCTCCCAAAACCAAGAAGCCCCCAAAGCCATCTGTTAGCAAAGCAAAGGGATTGAAGGTTGAgctgaacaaaaaacaaccaaagaTTTTTGATGAGTTCCAGGATCCCGCTGCGGAACGGGCCGCCGCTACTGCTGCATTACTGGCGCAACAGATGGAGGAGAATGAGGCGAAGCGCAAGGCGGAGGAGGAAACGCGCAAGATTCAAGAGGCTGCATGCGAGCAGCTCAATAGACTTCAAAAGCAGGTGCAGGTTGAGAAGGGCTCCTATGACAGCTACTATGGACAAAAAGCGGAGGCTGATGGCACTAACCTGGATGCTCTCAAATTAGATCACGTGTAA
Protein Sequence: MNEGSEYSIHSICRICLDHLRDDPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTNCYTKLNDLHGFQKLCVDSVQKFQEMVASNYFTPVIADINQIDNVDILHVPAHDGDMEEDRINFDPLLNTKIEIIENEEEVFKMLEDVDKEAEEVEKEESSSETDHDNDDDVDFEANSSESDDAMPLSRLRSTTRASKTKAKKSTPDDFDDESSSSDSDDDENDDDDDDDDKPRTKPKRKRIPAAERHLHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVETCRKGFTTAGGLRLHMDHAHSEFSEVHACTFEGCDKTFPRSVLLTFHMKKVHKVAKADTRNHPCTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKREAVPPATVVKPQEEGDAQNTQNVNQELNEPVDVKPVPIIPPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWAPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKPPKTKKPPKPSVSKAKGLKVELNKKQPKIFDEFQDPAAERAAATAALLAQQMEENEAKRKAEEETRKIQEAACEQLNRLQKQVQVEKGSYDSYYGQKAEADGTNLDALKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00508555;
80% Identity: -