Basic Information

Insect: Drosophila peninsularis
Gene Symbol: ZFY
Assembly: GCA_035047485.1
Location: JAWNPN010000014.1:2000152-2015691[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.1 74 4.1 0.5 3 21 470 488 468 492 0.91

2 14 0.36 24 5.6 0.1 2 21 514 533 513 536 0.88

3 14 0.18 12 6.6 1.0 1 23 553 576 553 576 0.95

4 14 0.28 19 6.0 0.2 1 21 581 601 581 605 0.90

5 14 0.0033 0.22 12.1 0.1 2 23 667 689 666 689 0.93

6 14 0.49 33 5.2 0.1 1 21 694 714 694 715 0.92

7 14 0.47 31 5.3 0.4 2 23 733 754 732 754 0.91

8 14 0.00012 0.0079 16.6 3.1 2 23 767 787 766 787 0.97

9 14 7.2e-05 0.0048 17.3 1.2 1 23 793 816 793 816 0.97

10 14 0.00059 0.039 14.4 1.0 1 23 835 857 835 857 0.98

11 14 0.0014 0.09 13.3 0.7 1 23 865 889 865 889 0.98

12 14 3.8 2.5e+02 2.4 5.6 1 23 894 918 894 918 0.93

13 14 0.00066 0.044 14.2 2.4 1 23 926 948 926 948 0.99

14 14 0.075 5 7.8 5.7 1 22 954 975 954 979 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.1	74	4.1	0.5	3	21	470	488	468	492	0.91
2	14	0.36	24	5.6	0.1	2	21	514	533	513	536	0.88
3	14	0.18	12	6.6	1.0	1	23	553	576	553	576	0.95
4	14	0.28	19	6.0	0.2	1	21	581	601	581	605	0.90
5	14	0.0033	0.22	12.1	0.1	2	23	667	689	666	689	0.93
6	14	0.49	33	5.2	0.1	1	21	694	714	694	715	0.92
7	14	0.47	31	5.3	0.4	2	23	733	754	732	754	0.91
8	14	0.00012	0.0079	16.6	3.1	2	23	767	787	766	787	0.97
9	14	7.2e-05	0.0048	17.3	1.2	1	23	793	816	793	816	0.97
10	14	0.00059	0.039	14.4	1.0	1	23	835	857	835	857	0.98
11	14	0.0014	0.09	13.3	0.7	1	23	865	889	865	889	0.98
12	14	3.8	2.5e+02	2.4	5.6	1	23	894	918	894	918	0.93
13	14	0.00066	0.044	14.2	2.4	1	23	926	948	926	948	0.99
14	14	0.075	5	7.8	5.7	1	22	954	975	954	979	0.93

Sequence Information

Coding Sequence: ATGAAGTCGCAGTCGGATGATCTGGACGATACGCACCTGTGCATCAAGTGCAACGCGACAATCGTGGGTCTGCGGAAATACATAGATCACCGCAAGCAGAATTGCCTGAGCATTGTCGGGAGTGATCGAAAAGAGAAGCGAGCGGTGGTCACTCGCTCCGGCTTGGAGCACAGCTACGATGGCTTCAACTTCACAGAGCCGGAGGCGCCGAGCAGCTACCTGAGCAAGACGACGGCCAGTCATGGCGGCAAGACCTCGAAATCCCTGACGGAGGCGTATGATGAGCTGGGCGCTGATGTGTTCTTCtcctcgctgcagctgcagagcgTCTCGACGGGCGGCAAGACGGTTGCGCGGCCCGAGCGTGGCGGCAAGGTGGGAGAGAGCTGGCATTCGACCAGAAGCTGCTCCGATCCACTGCTGAAGGCGGTGCGGGAGCAGGAGGAGTCCGACTTCAAGACGCTCAACTTTGTGCACTCGCCAGAGGCGAGCGAGGACGAGGAGAATGACGAGGAGCAGGATGACTCTGAGGGCGATGAGGATGAGGCAGATCAGatgcaggagcaggagcaggatcACGAGCAGGAGCCGGAACCCGATGAAGATCCCGATGCCGATCCTGATGATCCGGATTACGAGCCCGAATACGAGGGGCGACGGCACTCGCCGCCGACTGTGCCCGCCACGCACACAGGCGGCAAGTGGAAGCCGGAGCACCGGCCGCAGCTGCGCCACACGCACCTGGAGCGCATCTCGCCCAGCTGGGACGAGCCGCCCGAAGACGCCCACGATCATCCGCCCGCGGAGCACACACGCGGCAAGTGGGTGCCGGGCAGCAAGCAGCTGGAGTACCGCGAAAACATCGACCTGaccaagctgcagcagccggaCGCCAGCTACTGGTGCAACATCTGCTGTCGGCGCCTGAAGACGCGCCTCAACTACGACCAGCATCTGCGCAGTCGCTATCACCACAAGCGCGCGGACGCCGAGTGCCAGCTGGAGCAGGCCCATCTCGAGTCGGCCAATCTGACGGTCAGCACGAACTTCACCCAGCCGGCGCCAGACCGGAAGGAGGCAGCGCCGCgacgtcgtcgccgtcgtcgcacCGCCTTGCTGCGCTGCGACCTGTGCCGCACCAGCATGGCGCGCCACCTCATGGGCAAGCACCTGATCTCGCACTACCACTACCGccgcctgcagcagcaccagcagcagcagccggcccAGCAGCACAGCCAGGCCTCGCTGCACGCCATCCTCGAGCACATGGGCAGCATCGTGCGCCAGGCGCCCTTCCAATGCCTGCCCTGTCGCTTCTACGCCAACACAGAGGCAACTTTTCAGGCCCATTGGCGCTCTGCGGCCCACATCGAGGTGACCCAGCGGCTGGGCGGCAGCTTCTGGTGCGGCTACTGCCAGTTCGAGTGCGACACCAACGACGAGATGTGGCAGCACCTGCTGGGCACTGGGCACCGGGAGGTGCTGCTGGCGATCAATCGCTCGGTGCCCGTCTGCATCGCTCAGCGCCGGCACCTCAGCTGCGGCGTGTGCAAGGCCAGCTTCCTCTACAACGCCGAGCTGCGCAGGCATTTCGCCGCGCAGCACGCTGGGATGGTGGCCACGGGCAGCGCCTCGGATGACTATCAGTGCCGCTTTCGCTGTGGGACTTGTGGCGCCGCCCAAAGGTCGCGCGTGGCACTGCAGCGCCACGAGAAGCACAAGCATCGCGTGGACAGATACTTTTGCTCGGTGTGTCAGCTGGAGTTCGCGACGGCGCTGTCCGCGCGCCGGCACCGCAGCCTCCTGCTGCACAAGCGGCACGCGAACCGGCGTCCGAGCGCGGTCAAGTGCAGCAGCTCCGAGCAGTCGGCGCCGGCGCCGGAGAGTGAAATTGAGCACATGCTGCGCGAGGTGCTGGAGGAGCCGCAGACCGAGCAGCCCGACCAGGCCGAGCAGCCGACAACGAGCGCCAAGGCAGCGCAGCGGGCGGCTAGCCAGTGCGCCAACTGCTCGGAGAGCTTTGAGACATCCGAGGCCCTAATCCAGCACCGCAGCGAGGTGCATCCCATCGATAATCACGCCTGCCTCAGCTGTGGCGGCAGCTTCCAGTCCGCCCAGGCGCTCGGGCGGCACACGCGCAGCTGCCAGCCCATTGCCTCGATTTCTTCGTCTGCCTTGGCGGCTTCGGAATGGAACTGCGACCAGTGCGGCTTCAACACCCCATACGAATCGGATCTGCTCTATCATCGCTTCTTCCACGTGCGCGGCGCCTCCATTGGCAAGGACGAGCTGCTCCAATGCCCGCGCTGCCCCAAGAAGTTCCGCAAGCACTCGCTGCGCGCCCACCTGCGCAACCACACGAACGAGCGCATCTTCGAGTGCGCCGAGTGCCTGGCCAAGTTCGCCAGGCGGCACAACCTCAAGAACCACATGGAGACCATGCACAGCCAGCGCAAGAAGACCAAGGCCAAGCCGACGCCGGCCAAGGAAAAGCAGACGTTCCAATGCGGCACCTGCGGCAAAATATTGGCCAAGAAACACTCACTGCAAGTGCACGAACTGAAACATGACGAAAAGACGAAGAGTCGCTTCCGCTGCCCCAACAAGGACTGCTCCTATGCGGGCCGCACACGCGAAGGCCTCAAGACCCACCTCAAAACCCACTCCAAGGGCAAGCACAAGTGCTCGCACGAGAGCTGCGCCTACGTGGGCAAGAGTGAGCTGCACTTGAAGAGGCACCTCAAGACGCATCCAGTGGGGACTGACAGCGAATTCAAGTGCGAGCGCTGCGAGTTCAAGGCACGAATCAAGAGCGACCTGAAGCGTCACATGCGCCGACACACCGGAGAGAAGCCCCACAGATGCCCTCACTGCGAGTTCCAGTGCAGCAGCTTCGACAATATGCGCAAACACATCCTAAAGACGGGCAAACATCCAGGCAAGTTCATCTACAACTGCTCGAGCTGTACCACATTCAAGACCAACAACCTGAAGAAGTATCAAAACCATTTAATCACGCACGAGTCGGCAGCTCCATGTGACTAG
Protein Sequence: MKSQSDDLDDTHLCIKCNATIVGLRKYIDHRKQNCLSIVGSDRKEKRAVVTRSGLEHSYDGFNFTEPEAPSSYLSKTTASHGGKTSKSLTEAYDELGADVFFSSLQLQSVSTGGKTVARPERGGKVGESWHSTRSCSDPLLKAVREQEESDFKTLNFVHSPEASEDEENDEEQDDSEGDEDEADQMQEQEQDHEQEPEPDEDPDADPDDPDYEPEYEGRRHSPPTVPATHTGGKWKPEHRPQLRHTHLERISPSWDEPPEDAHDHPPAEHTRGKWVPGSKQLEYRENIDLTKLQQPDASYWCNICCRRLKTRLNYDQHLRSRYHHKRADAECQLEQAHLESANLTVSTNFTQPAPDRKEAAPRRRRRRRTALLRCDLCRTSMARHLMGKHLISHYHYRRLQQHQQQQPAQQHSQASLHAILEHMGSIVRQAPFQCLPCRFYANTEATFQAHWRSAAHIEVTQRLGGSFWCGYCQFECDTNDEMWQHLLGTGHREVLLAINRSVPVCIAQRRHLSCGVCKASFLYNAELRRHFAAQHAGMVATGSASDDYQCRFRCGTCGAAQRSRVALQRHEKHKHRVDRYFCSVCQLEFATALSARRHRSLLLHKRHANRRPSAVKCSSSEQSAPAPESEIEHMLREVLEEPQTEQPDQAEQPTTSAKAAQRAASQCANCSESFETSEALIQHRSEVHPIDNHACLSCGGSFQSAQALGRHTRSCQPIASISSSALAASEWNCDQCGFNTPYESDLLYHRFFHVRGASIGKDELLQCPRCPKKFRKHSLRAHLRNHTNERIFECAECLAKFARRHNLKNHMETMHSQRKKTKAKPTPAKEKQTFQCGTCGKILAKKHSLQVHELKHDEKTKSRFRCPNKDCSYAGRTREGLKTHLKTHSKGKHKCSHESCAYVGKSELHLKRHLKTHPVGTDSEFKCERCEFKARIKSDLKRHMRRHTGEKPHRCPHCEFQCSSFDNMRKHILKTGKHPGKFIYNCSSCTTFKTNNLKKYQNHLITHESAAPCD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -