Dpen009623.1
Basic Information
- Insect
- Drosophila peninsularis
- Gene Symbol
- zfh1
- Assembly
- GCA_035047485.1
- Location
- JAWNPN010000050.1:775515-801717[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.012 0.8 10.3 2.4 2 23 73 95 72 95 0.95 2 9 0.0044 0.3 11.6 0.1 2 23 288 309 287 309 0.95 3 9 3.1e-05 0.0021 18.4 1.8 2 23 323 344 322 344 0.97 4 9 1.1e-05 0.00073 19.8 6.4 1 23 353 375 353 375 0.99 5 9 0.00032 0.021 15.2 1.2 3 21 383 401 381 402 0.94 6 9 0.029 1.9 9.1 0.4 2 21 619 638 618 639 0.92 7 9 1.4e-05 0.00095 19.5 0.5 1 23 993 1015 993 1015 0.94 8 9 5.3e-05 0.0035 17.7 7.4 1 23 1021 1043 1021 1043 0.98 9 9 0.0027 0.18 12.3 4.3 1 21 1049 1069 1049 1070 0.96
Sequence Information
- Coding Sequence
- ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTTCTCCATGCAGTTTTCCTCTTTGGCCTCCAGTTTGCACCACCACCAAGCCCACAACAAGCCCAGCAATGCGGCCGCCAACCCAGAGCTGGCCAGCAGCGCCGCAGCCAGCGCGGCGGAGGACTGTTTGGTCAAGTGCACGCAGTGCCACAAGCGCTTCACCGAGTTCCAGTCCTTCAGCGAGCACATTGCCAGCGAGCATCCGCATGACAAGCTCAACTATGAGTCGCATCGTGCGGCAGCGGAGGCTGCGCAGCCGGAGAGCGAGGCGGAGGAGGACGAGCAGAGCaatttgagcagcagcagtcgtcgCTATGCCAAATCtccgaacagcaacaacaacaataacaacaacaacaacagcgagacAACAAAGAAtcagaataacaacaacagcagcggcagcggcagcggcagccataGAAGCCAGCACTCGCCGCTCTGCTCGCCTGTGGCCGCCACGCCCAACGATCTGTTTGCCCACCTGCCGCAtcagccgccgcagctgcccGCCCACTTGCACGCCCAGTTCATGGCCGCCGCCGCTTTGGCCATGCAATCCGCCCAGTCCGCCAGCTcgcccagccagcagcagcagcagcaacagcaacagcagctgcaacagtcgccgcagctgcagcaggcctTGCTGCTGCCCCCGCCGCAGcccggcagcaacagcagcgtcgGCAGCAACTCCGCCTATGACCTGGACCTGAGCGCACCGCGCTCCACCTCCAGCCCGGGCTCCACGACGGGCGACCTCGGCGCCGCCTTGCCCTGCATGCAGTGCACCGCCGCCTTCGCCAGCCGcgagcagctcgagcagcaccagctgctgcactcGCCCACGGGCCCACAGACCACGCAGAACGTGACTCAGACCTGCAAAATATGTCACAAGGCCTTCGCGAACGTGTATCGCCTCCAGCGGCACATGATCAGCCACGACGAATCCGCACTGCTGCGCAAATTCAAGTGCAACCAGTGCGACAAGGCCTTCAAGTTCAAGCATCACCTGAAGGAGCACGTGCGCATCCATTCCGGCGAGAAGCCCTTTGGCTGCGACAACTGCGGCAAACGCTTCTCGCACTCTGGCAGCTTCTCCTCTCACATGACCTCCAAGAAGTGCATTAGCATGGGGCTTAAGCTCAACAACAATCGCCAAATGCTGAAGACTCTGGACAAGAACTCAAGCGCCAGACGCTCACCCACggatcagcagcaacagctgggaGGCAAGCGGAAGCTGGCCGAGCAGGTGCTGCCCAATCCCATGAATTACTTTGCCGGCGAAGTGCAGAACCCACCAACCACAGTCAATGCTCCTGCGCCCTTCTATCCCAACTACAATGCCATGAATGCGGCTTTGCTGGCATTCCCGAATGCCTTTATGGCCGCCGCACTGGATCCTCGCATGCATCCCTATAGCATACAGCGACTGCTGGAGCTGACTGCtgccgggcagcagcagcagcgggaggaGGAGCACAGAGAGGAGCAGAAGCTGTATGAGACCAGCAAAGATGACGATGAGACGCCAGATGAGCCCAAATTGGTTATGGACTTAGAGGAATCGGAGCCCAAGCCTGCGACTAGCCCCGAATCAGCCGTAGCTGAGCCAGTAGCTATCGACGTGGGCGTCGTTAAGCAGGAGCCCAGTCGCGAACCGACGCCTCCGGACACGCCCAAGTCTATCAAAGTGGAGCacgaggaggagctggagcCAGTGGTCGTGGAGCAGTCGCGGCCACAGACACCTCAAGATCTGCGCTGCAGTCGGTGCGCCAAGCAATTCAATCATCCCACAGAGCTGGTGCAGCACGAGAAGGTGCTGTGCGGCCTCATCAAagaggagctggagcagcaataccaacaacaacatcaacaacagcagcagcaacaacaacagcaacaacaacaacagcagcaacatcaacaacaaacaagcttTGCTCTGCTGCCCTCAGCAAGCGATGCGgacgaggatgaggaggaCGAAGAGGAGCCTCGCCAGGACTACCATGCTGGCAGCAGCGACAGTGGCGAGCGTAAGGTGCGCGTGCGCACCGCCATCaacgaggagcagcagcaacagctcaagCAACACTACGCCCACAATGCGCGTCCCAGTCGTGATGAGTTCCGCATGATCGCCGCCCGCTTGCAACTGGACGCGCGCGTCGTCCAGGTCTGGTTCCAGAACAATCGTTCGCGCGAACGCAAGCTGCAGAGCTATGCAAGCAACGGCGAggccacagctgcagcagctccagcactACCGCAGCCCCGCGCTGGCGAGGATCAGCCCCTGGACTTGTCCGTGAAGCGTGATGCTTCGCCCTTGTACGGCTTGTCGGCCCAGCAAGCAGCTGTGCTGCCCGCGCCCGCTGACTACCAGGAGACCATGGCCATTAATCTGAGCCGCAAGTTGTCCGGATCGGCGTCCATGTCGCCGGCTTCGTTGTCGCCCTGCTCGGGCGCTTCATCCCTGCAGCAgtcggcggcagctgctgctgccgctgcagcgctTTACTTTGCGCCTCCCTCGCCGCCCAGCCTGCACGAGTCGGCGCCTGCGCCCGCACCGCGTGGCCAGGCATTCGCTGGGCTGCCGCCTTACATGCTGCCACGCCTGCCCATGGAGGCACTTTTCCAGATGCGGCCCGGCGGCGACTATGCGCCCAATCCGCTCATGAACAGTATTAAGCTGCCCGACTACCGCGGCACCAGCCTCAGCCCCGGCGGCTCCGAGAAGCGTTCGTGGCGCGACGATGATTCGCGTATCTCGCACGAGGATGACTACGTCCTGGCGAGCGGTGGCCTGCTGCCGCCCAAGCCTAAGCGGGCCAAGGCCGAAACGCACGGACATGCGGGCGATCCGGACTTGCCCTTCGTCTGCGATCAGTGCGACAAGGCGTTCGCCAAGCAGAGCTCTCTGGCGCGCCACAAGTATGAGCATTCCGGTCAACGACCCTATCAGTGCATGGACTGCCCCAAGGCTTTCAAGCATAAGCACCACTTGACGGAGCACAAGCGTCTGCATTCCGGCGAGAAGCCATTTCAGTGTTCCAAGTGCTTGAAGCGCTTCTCCCACTCGGGCAGCTACAGCCAGCACATGAACCACCGTTACTCCTACTGCAAGCCCTACAGGGAATAG
- Protein Sequence
- MLSCLAPSSTRFGQEDNIIQQSMPSSTAFSMQFSSLASSLHHHQAHNKPSNAAANPELASSAAASAAEDCLVKCTQCHKRFTEFQSFSEHIASEHPHDKLNYESHRAAAEAAQPESEAEEDEQSNLSSSSRRYAKSPNSNNNNNNNNNSETTKNQNNNNSSGSGSGSHRSQHSPLCSPVAATPNDLFAHLPHQPPQLPAHLHAQFMAAAALAMQSAQSASSPSQQQQQQQQQQLQQSPQLQQALLLPPPQPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLGAALPCMQCTAAFASREQLEQHQLLHSPTGPQTTQNVTQTCKICHKAFANVYRLQRHMISHDESALLRKFKCNQCDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRQMLKTLDKNSSARRSPTDQQQQLGGKRKLAEQVLPNPMNYFAGEVQNPPTTVNAPAPFYPNYNAMNAALLAFPNAFMAAALDPRMHPYSIQRLLELTAAGQQQQREEEHREEQKLYETSKDDDETPDEPKLVMDLEESEPKPATSPESAVAEPVAIDVGVVKQEPSREPTPPDTPKSIKVEHEEELEPVVVEQSRPQTPQDLRCSRCAKQFNHPTELVQHEKVLCGLIKEELEQQYQQQHQQQQQQQQQQQQQQQQHQQQTSFALLPSASDADEDEEDEEEPRQDYHAGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRMIAARLQLDARVVQVWFQNNRSRERKLQSYASNGEATAAAAPALPQPRAGEDQPLDLSVKRDASPLYGLSAQQAAVLPAPADYQETMAINLSRKLSGSASMSPASLSPCSGASSLQQSAAAAAAAAALYFAPPSPPSLHESAPAPAPRGQAFAGLPPYMLPRLPMEALFQMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVLASGGLLPPKPKRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00530857;
- 90% Identity
- iTF_00559678;
- 80% Identity
- iTF_00573216;