Basic Information

Insect: Drosophila peninsularis
Gene Symbol: ham
Assembly: GCA_035047485.1
Location: JAWNPN010000047.1:120961-145616[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.56 37 5.0 0.0 2 21 342 361 341 364 0.87

2 9 0.011 0.75 10.4 1.6 1 23 371 394 371 394 0.91

3 9 1.8e-07 1.2e-05 25.5 1.7 1 23 400 423 400 423 0.96

4 9 3.4e-07 2.2e-05 24.6 1.5 1 23 429 451 429 451 0.97

5 9 8.6e-05 0.0057 17.0 3.8 1 23 457 479 457 479 0.97

6 9 0.0019 0.13 12.8 2.0 2 21 487 506 486 507 0.94

7 9 6.6e-09 4.4e-07 30.0 1.3 1 23 988 1010 988 1010 0.99

8 9 3.5e-07 2.3e-05 24.5 0.9 1 23 1016 1039 1016 1039 0.97

9 9 4.5e-05 0.003 17.9 6.8 1 23 1045 1067 1045 1067 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.56	37	5.0	0.0	2	21	342	361	341	364	0.87
2	9	0.011	0.75	10.4	1.6	1	23	371	394	371	394	0.91
3	9	1.8e-07	1.2e-05	25.5	1.7	1	23	400	423	400	423	0.96
4	9	3.4e-07	2.2e-05	24.6	1.5	1	23	429	451	429	451	0.97
5	9	8.6e-05	0.0057	17.0	3.8	1	23	457	479	457	479	0.97
6	9	0.0019	0.13	12.8	2.0	2	21	487	506	486	507	0.94
7	9	6.6e-09	4.4e-07	30.0	1.3	1	23	988	1010	988	1010	0.99
8	9	3.5e-07	2.3e-05	24.5	0.9	1	23	1016	1039	1016	1039	0.97
9	9	4.5e-05	0.003	17.9	6.8	1	23	1045	1067	1045	1067	0.98

Sequence Information

Coding Sequence: ATGTTGTTCGAAAGTTATATTATGCCAGGCTCTAACGGCGACGACTACGATCCGAGCGTCGTGCgccatcaccatcatcatcgtcatcactTGGATCTCAGCAGCGGAGCGCCGGCCTTTGGTCCCCTGCCGCCGGCGCATCTAAGCTCCAGCCAGGCTCGGCCCGAGGAGACGTTCGGCCGTCATCTGCCGCCCACGATATCCCCGCCACCCGCCTCGCTGCtacagcagcagtcgcagtcacagcagcagccgtcgctgccgctgccgccgccgccgacgcATTTAGCCCTGCatttgcagcaacagcgactgcaACGCTCGCCGCCCGCTTCCGCATCCGCCTCGATCTCTGCCTCCGGCAGCAATATGGAGCACCTGACGCAGGAGTTTCTATTGCAAATGGCGCGCCTGCGCGACCCCTTCGGCGATCTGGACATCCGTGATACAGGCGTCTACGCCAAGACCGACTTGCCACGCGACTCCCGCTACGGACCCTTTCCCATGCACCTGTGTCAGCAGCCCAGCGATCGCCATCTGGCCTGGGAGGTAATTGCCGGCCCGCTGTTCCATGGCTGGCTGGAGCCCTCAGCGGACGTGGCCACATGGCTGAAAAAAATACGCAACGCCCCGGTCGACGAGGCTGAAGAGGCTAATTTAAGGCATTTCGTGGTGGATCGCTGTCTGTGGTACGAGACGAAGCGCGATATTAGCGCGGGCGCCGAGATCGTGGTCGACGCGCGCTCCCGCACGCCCTACGACATCAGCGACAGCCTGCGGACGTCGGCGAcagcctgcagcagcagcagcggtagcagcgcagcggcagcggcagcagccgccgccgcagccgcagccgccatGGCAgcggccagcaacaacaacaacaacaacagcgatgATCGCAGCGATCGTGATAACGgCTTTTACAGCGGCGACGAATTTGCCAAGGATAAGAAAAACCTATCGATAATTAGTCAGGGCGACAACGATTTCACAGACGACGAGAACGGTTTCGACATACGCTGTGAGGTCTGTGATAATGTCTATACGGATTTAGAACGCCTCGACGAACATCTGGTGGGCGCGCATCACTTCAAACGCGGAGAATTCGCCTGCGAGCTCTGCCCCCAACACTTCTGCCATCGTCCATTGCTGATCAAACACGGAGCGATCGCTCATAACAATATAAGGAAATATTCCTGCGAGAACTGTTCCAAGGTATTCTGTGACCCATCGAATTTACAGCGCCATATTCGCGCCTATCACGTCGGCGCTCGCAGTCACCCGTGCCCGGAGTGCGGTAAAACATTCGCCACATCGTCCGGCCTgaagcagcaccagcacaTCCACTCCTCGGTCAAGCCGTTCGCCTGCGAGGTCTGCTTCAAGGCGTACACGCAGTTCTCCAACCTGTGCCGGCACAAGCGCATGCACGCCGACTGCCGCATGCAGATCAAGTGCAAGAAGTGCAACACGAGCTTCAGCACGGTCACCTCGCTCTCGAAGCACAAGAAGTTCTGCGACAGCTCCGACAGCTtccgcagcagccagcagagtcgcctgcagcagcagcaccagcagcagcagcaccagcagcacgtgtcgcaccagcagcagtcgcaagCGGGGCAACTGCTCCTGCCACCCGGTGCTCATCAGCGActcgcagccgccgccgccgctgccgcagccagcagcaacagcagcgacgcaGGCGCCATGGCGACGCCGCCGAACCACATGTTCACGATGCATCCCTCGCACTCCTTCTTTCCGGGCTTCCCGCCGTACGCCTTGCCCAGCTTCTTCACGAACTGCCgcccgcagccgctgctgccgcacaTGTTCCCCAATCCGCATCTGGGCGACATGGGCCGCGGCCTGGTGGCGCCGCTGGTTTCACCGAACGCTGccttccagcagcagctgcaagcgGCGATGAGTCTCAAGTCGCCGGAGTCGCCGCGCCTCAAGCGCGAGTCCAGCACGCCGGAGCGCAAACCCATCAAGGCCGAGCTTCAGCCCAGCGacgatgaggaggaggaggaggagtccAATTCCTATGATCAGCTGCAATTGAAGCTGAGCTCCAGCAAGGAGTCGAGCAAGCTGAAGTCGGAGTCAAAGGCGGAAGCTGGCGGCTCACAGCCAGCAGAGCCGGACGATCAAGATCatactaatgataatgacaatgacaatgataatgatgttgACAATGATAGGAAATCCATTGACATAATGAGCACACCACCGCCCGCTGAAACGGAGCTGCAGCCGGAGCAGGACAAGGGCACCGTTGACCTGCTGCCGCTGGATCTGTCCATCAGTCGCAAGCGCCGCAGCTCCCTGTGCACGGCCAGCACGCCCGTGCCGCTGGCCATTTCGCTGTCCAGCCGCACGTCCACGCCCGCCCTGGAGATAGCGGAGGGCGCTGCCGGGCAGCCGCCCATGAAGCTGATGAAGCACAGCTCCGGCGAGTCGTCCACCTCGCATCAGTCCTTCAAGGGCAGCAGTCCCACGCCGAGTGTCAGTGCCTCGCCCGGACccacgccctcgccctcgccgccCATCAGCACTGGCGGCGAGCTGAGCAGCATGTCCGAGAGCGCGGCGTCCGCCGCCGTTGGCGCTGCCTCGgcggcggctgccgctgcgtcGGTGATGGCCTGTCCGCGGCAGCTGCatccgcagctgctgctcgaggaGCTCTATCGCTCGCGCTTCAACACGCCACCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGCCACACAAATCGCCGGCTGCTtgcatcagcagcggcagcagctcgctTCATCTGCCGCTTCCGCCCGAGCACAATTTCCACGAGGCTCTTCGAGCCGCCGGCctggccgcagccgctgccagcgtctgcagcagcggcgccagcGCCGTCACCGCCAACGGCGGCAAGCTCAAGGACCGCTACACCTGCAAGTTCTGCGGCAAGGTCTTTCCGCGCTCCGCCAATCTCACCCGGCACCTGCGCACCCACACGGGCGAGCAGCCGTACACGTGCAAGTACTGCGACCGCGCCTTCAGCATCTCCTCGAATCTGCAGCGCCACGTGCGCAACATCCACAACAAGGAGCGCCCCTTCCGGTGTCACATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGGCACCTGAAGAAGCACGAGGCGGATGCGGGCGGCTTCGAGTACAACGACTCGCCCAGCTCGAACGAGGCCAACGATCGGGAGGAGGCCTGCTTCGACGACATCCGCTCCTTCATGAAGCGCGTCTACACGCCCACGAGTCTGGGCGGCGCGGATGGGGACACCGAGGAGTACGCGGGCAGCGATGACCAGTTGTCCGTCTCGACGCGCCACTCCGTCAACTTTGACAAGGAGCTGCTGGctaatggcaacaacaacaacaccaacaacactaacaacaacaacaacaacagcagcaacagcagcagcaacaacaacaacaatcagacAGGTCTGGGCGACACGATCGCGGTCAGCACttag
Protein Sequence: MLFESYIMPGSNGDDYDPSVVRHHHHHRHHLDLSSGAPAFGPLPPAHLSSSQARPEETFGRHLPPTISPPPASLLQQQSQSQQQPSLPLPPPPTHLALHLQQQRLQRSPPASASASISASGSNMEHLTQEFLLQMARLRDPFGDLDIRDTGVYAKTDLPRDSRYGPFPMHLCQQPSDRHLAWEVIAGPLFHGWLEPSADVATWLKKIRNAPVDEAEEANLRHFVVDRCLWYETKRDISAGAEIVVDARSRTPYDISDSLRTSATACSSSSGSSAAAAAAAAAAAAAAMAAASNNNNNNSDDRSDRDNGFYSGDEFAKDKKNLSIISQGDNDFTDDENGFDIRCEVCDNVYTDLERLDEHLVGAHHFKRGEFACELCPQHFCHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCKKCNTSFSTVTSLSKHKKFCDSSDSFRSSQQSRLQQQHQQQQHQQHVSHQQQSQAGQLLLPPGAHQRLAAAAAAAAASSNSSDAGAMATPPNHMFTMHPSHSFFPGFPPYALPSFFTNCRPQPLLPHMFPNPHLGDMGRGLVAPLVSPNAAFQQQLQAAMSLKSPESPRLKRESSTPERKPIKAELQPSDDEEEEEESNSYDQLQLKLSSSKESSKLKSESKAEAGGSQPAEPDDQDHTNDNDNDNDNDVDNDRKSIDIMSTPPPAETELQPEQDKGTVDLLPLDLSISRKRRSSLCTASTPVPLAISLSSRTSTPALEIAEGAAGQPPMKLMKHSSGESSTSHQSFKGSSPTPSVSASPGPTPSPSPPISTGGELSSMSESAASAAVGAASAAAAAASVMACPRQLHPQLLLEELYRSRFNTPPFHFLGQMGGRPGFEPHKSPAACISSGSSSLHLPLPPEHNFHEALRAAGLAAAAASVCSSGASAVTANGGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHMCDRCFGQQTNLDRHLKKHEADAGGFEYNDSPSSNEANDREEACFDDIRSFMKRVYTPTSLGGADGDTEEYAGSDDQLSVSTRHSVNFDKELLANGNNNNTNNTNNNNNNSSNSSSNNNNNQTGLGDTIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00568407;
90% Identity: iTF_00493810;
80% Identity: -