Dpen008182.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila peninsularis
Gene Symbol
su(Hw)
Assembly
GCA_035047485.1
Location
JAWNPN010000044.1:577732-580789[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00065 0.043 14.3 2.2 1 20 220 239 220 241 0.94
2 12 2.7e-06 0.00018 21.7 0.4 3 23 292 313 290 313 0.93
3 12 0.0078 0.52 10.9 0.2 1 23 319 341 319 341 0.96
4 12 7.4e-07 4.9e-05 23.5 2.5 1 21 348 368 348 369 0.95
5 12 3.2e-06 0.00021 21.5 0.6 2 23 381 402 380 402 0.96
6 12 0.0001 0.0068 16.8 5.3 1 23 413 435 413 435 0.99
7 12 7.9e-05 0.0053 17.1 0.9 1 23 441 463 441 463 0.97
8 12 1.6e-05 0.0011 19.3 0.8 1 23 469 491 469 491 0.99
9 12 1.5e-06 9.7e-05 22.6 3.0 1 23 497 519 497 519 0.98
10 12 0.0032 0.21 12.1 1.4 1 23 523 545 523 545 0.97
11 12 2.9e-05 0.0019 18.5 0.1 1 21 553 573 553 577 0.91
12 12 5.6e-05 0.0037 17.6 0.3 3 23 597 618 595 618 0.96

Sequence Information

Coding Sequence
ATGAGCGCCAGCAAGGAAGCCACCGCGGCAGCCCCTGCCACCAACAAAGAAGCGAGCACTCCCGTCATCAGAGTAATGGACGTGGAGAAATTGGTCAACAAACGCACTGGCACACGAATGAAGCTACTCAATGATGTGGCCGCCAAGGCAGCTCGCCCCAAGCAGGAGAAGCGCACCAGCATCAAGATACTCAACAACGATGAAGCCCAGAGCAGTTCGAAGGGCGGCGACAAGCGTGCCACGCCCAAAACTGTTAGCCCAGCTGTTAAGATATTAAACGAGAAGCGAATTGCACCTTCAGCCGCAATAATGGAAACAGCCAAGATAAAGACATCGcccagcaagaagaagaaaatggaTCACTATGTGCTGCAGGCCATCAAAAGTGAGAACAGCAAAGCGGACAACACGACCAGCGTTGTGGTTGTCGAGGACGAAGACACCATTGACTTCATACTGGCCGACGATGACGTAGAGCTCGGAGATACTGCCAAAGAGAATGGCGAGGAGTTTGTGGTATCTGGCGTCgaggatgacgatgacgaagacgatgacgatgatgacgacgacgaggatggGTCAGGAGGGGGTGCCAGCGGAGCAAAGCGCAAGAGTGCGAAtgggagcaacaacaacgagctgAAAGAAATGGTCGAGCACGTATGCGGCAAATGCTACAAGACGTTCCGTCGCGTCAAGAGTCTGAAAAAGCATTTGGAGTTCTGTCGCTACGACAGTGGCTACCATTTGCGCAAGGCGGACATGCTGAAGAACCTGGACAAGATTGAACGCGATGCCGTGGTTATGGAGAAGAAGGACATTTGCTTCTGTTGTAGTGAGAGCTACGACACTTTCCACCTGGGCCACATCAACTGCCCTGACTGCCCCAAGTCGTTCAAAACGCAGACGAGCTATGAGCGTCACATTTTCATCACACACTCGGAATTCAACGATTTTCCATGCTCCATTTGTAATGCCAAGCTACGCAGCTCAGCGCTGCTGAAGctgcacgagcagcagcatcagtcTAGGGGCAAGCCGTTTGCCTGCAAGATCTGTGGCAAGGACTTTACGCGCTCGTATCATCTGAAGCGCCATCAGAAGTATTCGTCGTGCTCGGCCAACGAGAACGACACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTATCGCTTAGACAATCTGCGCGCCCATCTCAAGCAGCACCTGGGCACCCAGGTGGTGAAGAAGCCGGAGTACATGTGTCACGTTTGCAAGAACTGCTTCTACAGTCTGTCCACACTCAACATTCACATACGCACTCATACGGGCGAGAAGCCTTTCGATTGCGATCTGTGTGACAAGAAATTTTCGGCTTTGGTAGCGCTCAAGAAACATCGTCGCTATCATACGGGCGAGAAGCCCTATACCTGCACAGTGTGCAGTCAGTCCTTTGCCGTGAAGGAGGTGCTCAATCGCCACATGAAGCGGCACACGGGCGAACGTCCGCACAAGTGCAACGAGTGTGGCAAAAGCTTCATACAGGCCACACAGCTGCGCACGCATTCCAAGACGCATCTGCGTCCCTACTCCTGCTCCCTGTGCATTCAAAAGTTTAAGACGGAGAAACAACTCGAGCGTCACGTCAAGGAGCATTCGCGTCAGAAGCGCCCCTCCTTTGCCTGTTCCGAGTGCACACGCAGCTTCCGCACCAGCGCACTACTCAAGGAGCACATGGAGGCTGGCGATCATTCGCCTGTCAAGCCGACTCGGGCCAAACGTTCGGCCAAGGTGATCGAGCGCACGGATTGTGCGATTTGTGACAAGAACTTCGACAGCACTGATACACTCCGTAATCACATACGTAACGTGCACGAGTGCGATCCGGATGATATTTTCGGCACAGAGCCACCAGCCAAGCGCAAAGCTAACAAGAAGGCAGTTGTTGTGGTAGATGAGGAAGAGGACACAAGTGAAGAAAACGACCAGGATAAGGAATCACAGGCTGCCAACACATCAGCTGGCTCACTCATCTCCAGCAAAACGGATGACAATGGAGTCGTGGTGCGTGAGTTTTTGGTGGATGAGGGCGATGGCAATGCGCAAACCATTCTGCTCGAGAACGAGGTGTACACAATTTTGCCTTTGGAGGGTGCAGCCAGCACAGCCGAGCCGACGACCGAAGACAGTGACGTCAAGGCCGAGTCTAAGGAGAAGCCAAAGGCGGCAGTGTCGCCGATTGTGAAGAAGGAGCAGCGTAAATCGTTGGCCGCCAGTTTGGCCGCTGCTATTGCGGATAATCTAGATGAGCCGTCAAGCGACGATGAGTTCAACGGCGAGGTGCTCACTGAGGAGGATATTAAACTAAAGGAGAACATAGCGAAGTTAATCGATATGCTTGTCGATCCGCAAACACTAAAGAAGTACAACTGGCCCAACAGCTCCGAGGAGTCGGTGCTATGCAAGGTCATCGAGAATTGTGGCCACGATCTGGCCAAGGGCAGCGAAGCCTATGCCGAGTTGGACTATGGCAGTCGTATGCGTGAATATTGCAAACTCCTCTTCACGGTGGTTATTCACAATGATTCCATAAAGGCGTTGCTCAACAACTTCCCCATCGACGATGTTATTGAGTATGTGTTGGGCGATGAGGACCAGGACCAGGACCAGAGTCAGGACCAAGAGACAGACAAGGCGAAAGAGAAGGAGAATGACGCAGATAAATCAGATACAGACATTAGGCGGAATGAAGCTGATGAAGCCGAGGCTTAG
Protein Sequence
MSASKEATAAAPATNKEASTPVIRVMDVEKLVNKRTGTRMKLLNDVAAKAARPKQEKRTSIKILNNDEAQSSSKGGDKRATPKTVSPAVKILNEKRIAPSAAIMETAKIKTSPSKKKKMDHYVLQAIKSENSKADNTTSVVVVEDEDTIDFILADDDVELGDTAKENGEEFVVSGVEDDDDEDDDDDDDDEDGSGGGASGAKRKSANGSNNNELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLDKIERDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDFPCSICNAKLRSSALLKLHEQQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYSCSLCIQKFKTEKQLERHVKEHSRQKRPSFACSECTRSFRTSALLKEHMEAGDHSPVKPTRAKRSAKVIERTDCAICDKNFDSTDTLRNHIRNVHECDPDDIFGTEPPAKRKANKKAVVVVDEEEDTSEENDQDKESQAANTSAGSLISSKTDDNGVVVREFLVDEGDGNAQTILLENEVYTILPLEGAASTAEPTTEDSDVKAESKEKPKAAVSPIVKKEQRKSLAASLAAAIADNLDEPSSDDEFNGEVLTEEDIKLKENIAKLIDMLVDPQTLKKYNWPNSSEESVLCKVIENCGHDLAKGSEAYAELDYGSRMREYCKLLFTVVIHNDSIKALLNNFPIDDVIEYVLGDEDQDQDQSQDQETDKAKEKENDADKSDTDIRRNEADEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00495995;
90% Identity
iTF_00502661;
80% Identity
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