Basic Information

Insect: Drosophila pegasa
Gene Symbol: -
Assembly: GCA_035046225.1
Location: JAWNOD010000398.1:17660983-17663199[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 5.4 3.3e+02 1.9 0.1 1 17 237 253 237 254 0.89

2 8 2.9e-05 0.0018 18.5 2.5 1 23 410 432 410 432 0.97

3 8 2.3e-05 0.0014 18.8 0.2 1 23 438 461 438 461 0.97

4 8 0.13 8 7.0 2.0 1 23 467 490 467 490 0.93

5 8 3.2e-06 0.00019 21.5 1.8 1 23 530 552 530 552 0.96

6 8 0.0014 0.085 13.2 1.4 1 23 558 580 558 580 0.98

7 8 0.00012 0.0077 16.5 0.4 1 23 586 608 586 608 0.98

8 8 0.004 0.25 11.8 5.1 1 22 614 635 614 638 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	5.4	3.3e+02	1.9	0.1	1	17	237	253	237	254	0.89
2	8	2.9e-05	0.0018	18.5	2.5	1	23	410	432	410	432	0.97
3	8	2.3e-05	0.0014	18.8	0.2	1	23	438	461	438	461	0.97
4	8	0.13	8	7.0	2.0	1	23	467	490	467	490	0.93
5	8	3.2e-06	0.00019	21.5	1.8	1	23	530	552	530	552	0.96
6	8	0.0014	0.085	13.2	1.4	1	23	558	580	558	580	0.98
7	8	0.00012	0.0077	16.5	0.4	1	23	586	608	586	608	0.98
8	8	0.004	0.25	11.8	5.1	1	22	614	635	614	638	0.91

Sequence Information

Coding Sequence: atgaagTGTGCAGTGCAAAACTGCGCAAACAAGTTCAGGTCACGACAAAAACACTCGGAACAATTGAGTTTCTTCAGCTTTCCCAAAAATCCGGACGTCTTAAAAAAATGGCTTTCATTTTGCCGCAGATACAACAAAGAAAAGCTAAAGGCGCCCCTCAAGAGCGTTCTTTGCAACGAGCATTTTAAAGAGGAGGATATTCAGGGAGCATTACAATTTCAGATGGGTCTGTGCAGTAAAAGAACCCTGCGACCGGGCGCTGTGCCGTGCATAAACAAAAACGACGTGAGCGCAGTCGAGCGGGAGCGATCTGAAAGGCGCAAGAACAAAAAGCTGGTCGCAGAGCTACTGGAGGAAGCGGCAGCGCGAGAAGCTGCCGAAGCCAGCGGGGCGATTGTTATAGCGCCAGACTTTATTAGAAATACAGGCATTGTCTCGGTTCCCGACTTCGTTGTTGCTACAGGCAACGCCTTCATTCCCTGCACCCAGACACCCAGTGAAAACGATCCCCTGGCTGAGGAGCAGGCGGAGCAGGAGTCGTGCCGAGATGAAAGAATTATTGAACAGATTAAGTGCCGCACCTGCTATGAACCATTTGTTGTCGACGAGAATGCCAAAGACCTTTGTGACGAACAAAACGCCGTCATGTTGTTTCACATTGAAGTTATAACCGGAATTTGGATCCAGTGTAAAGAAGGAATATCGCCGTTCATGTGCTCAAACTGCGTCTATAGTCTGCGCACAGCCATTAATTTTCGAGAAACATGTATTCGAACGGAAGTAGAGCTAGCGGAAAGGGATACGATTATTAAGGAGAACGACGGAGACGCTTGGAATGCTAATGATGCAGAGATGGTGCCGATTAGCGAGAGCAATGTTAATGACTATGCTACTATATTTCCGGCAGAAGATCAAAATGAGCAAGCCCCTGTTGTTGAGTCTATGCCTTTGGAAATAACacaagaaaatattcagcCCATATATACATCAGCTGGGGATTCTAATAGTATTGCGTTGGGTGCTCAGATTTACGAGGATCTTCTCAATGAATACAGGGGTAAGGACAGAGTAGCACGTCCACGACAGAGAAAGGTATCGATAAATAGGACAAAAGTGGCAagaaagcgaaagcgaaaaaCTAGGGATCCCAAGCCGAAGCGACCGAAGCGTACAAAAGAGGAAAGAAATCGCATACGTCGCGAGCAAATCCGAGCTATGCCCTTGAATCATGTGTGCGATCAGTGCGGCGCCTCGTTTCGGGTGAGATGTAACCTAACGATCCATATGTTGAGGCACACGCGCACAAAGAACTATCCTTGTCCCGAGTGCCCCAAAAAATTTTACGATGCCTATATGCGAAATATTCACATCCGTGTGCGGCACAAGGGCGAATTGCCATTCGAATGCAAATTCTGTAGGAAAGCATTTGGCTCTTCCAATACGCGTTATCTGCACGAAAAAAAGGTTCACGGAGCATCGCCACGTATTCACAGAAACCTGAGTAGATTGAATAAAAGAATCGAGCTTAAAAATGAGCAGGAGGACCATCAACAGGCTACTGGGCTGGGACAAAAGGAAAGTGTTCGGCACTTTTGCACATATTGCAATAAGAGCTATGCGACAAAATATGCCCTCAACTGGCATATCAATGTGCACATGGGGATCAAGCcgtttaaatgcaaattctgCGACATGGGCTTTGCAGATCCCCAATCGAAGAAGAAGCATGAAATGAAGCACGATAGCAAACGTCCCTACGAATGCGACATTTGTCTTAAAGGGTTCTACGTGCGCAGCAAGCTGAAGGAACATGAACGTATTCACACTGGCGAACGACCCTATAGGTGTGAAGTCTGCAACGCCTTCTTCCGTTACAAGTTCAACTTGTGCTCGCATCAGTTTAGCAAAATGCATAAGGAGAATCTACAAAAGCTAACAAAAGTTGAAGTGATTGAAGATTCTAATTAA
Protein Sequence: MKCAVQNCANKFRSRQKHSEQLSFFSFPKNPDVLKKWLSFCRRYNKEKLKAPLKSVLCNEHFKEEDIQGALQFQMGLCSKRTLRPGAVPCINKNDVSAVERERSERRKNKKLVAELLEEAAAREAAEASGAIVIAPDFIRNTGIVSVPDFVVATGNAFIPCTQTPSENDPLAEEQAEQESCRDERIIEQIKCRTCYEPFVVDENAKDLCDEQNAVMLFHIEVITGIWIQCKEGISPFMCSNCVYSLRTAINFRETCIRTEVELAERDTIIKENDGDAWNANDAEMVPISESNVNDYATIFPAEDQNEQAPVVESMPLEITQENIQPIYTSAGDSNSIALGAQIYEDLLNEYRGKDRVARPRQRKVSINRTKVARKRKRKTRDPKPKRPKRTKEERNRIRREQIRAMPLNHVCDQCGASFRVRCNLTIHMLRHTRTKNYPCPECPKKFYDAYMRNIHIRVRHKGELPFECKFCRKAFGSSNTRYLHEKKVHGASPRIHRNLSRLNKRIELKNEQEDHQQATGLGQKESVRHFCTYCNKSYATKYALNWHINVHMGIKPFKCKFCDMGFADPQSKKKHEMKHDSKRPYECDICLKGFYVRSKLKEHERIHTGERPYRCEVCNAFFRYKFNLCSHQFSKMHKENLQKLTKVEVIEDSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516527;
90% Identity: iTF_00519953;
80% Identity: iTF_00572632;