Basic Information

Insect: Drosophila pegasa
Gene Symbol: zfh1
Assembly: GCA_035046225.1
Location: JAWNOD010000398.1:11600687-11629108[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.012 0.75 10.2 2.4 2 23 73 95 72 95 0.95

2 9 0.0013 0.082 13.3 0.1 1 23 289 311 289 311 0.97

3 9 3.2e-05 0.0019 18.4 1.8 2 23 325 346 324 346 0.97

4 9 1.1e-05 0.00069 19.8 6.4 1 23 355 377 355 377 0.99

5 9 0.00033 0.02 15.2 1.2 3 21 385 403 383 404 0.94

6 9 0.029 1.8 9.0 0.4 2 21 631 650 630 651 0.92

7 9 1.5e-05 0.0009 19.4 0.5 1 23 1013 1035 1013 1035 0.94

8 9 5.4e-05 0.0034 17.6 7.4 1 23 1041 1063 1041 1063 0.98

9 9 0.0027 0.17 12.3 4.3 1 21 1069 1089 1069 1090 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.012	0.75	10.2	2.4	2	23	73	95	72	95	0.95
2	9	0.0013	0.082	13.3	0.1	1	23	289	311	289	311	0.97
3	9	3.2e-05	0.0019	18.4	1.8	2	23	325	346	324	346	0.97
4	9	1.1e-05	0.00069	19.8	6.4	1	23	355	377	355	377	0.99
5	9	0.00033	0.02	15.2	1.2	3	21	385	403	383	404	0.94
6	9	0.029	1.8	9.0	0.4	2	21	631	650	630	651	0.92
7	9	1.5e-05	0.0009	19.4	0.5	1	23	1013	1035	1013	1035	0.94
8	9	5.4e-05	0.0034	17.6	7.4	1	23	1041	1063	1041	1063	0.98
9	9	0.0027	0.17	12.3	4.3	1	21	1069	1089	1069	1090	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTTCTCCATGCAGTTTTCCTCTTTGGCCTCCAGTTTGCACCACCACCAAGCCCACAACAAGCCCAGCAATGTGGCTGCCAACCCAGAGCTGGCCAGCAGCGCCACAGCCAACGCGGCTGAGGACTGCTTGGTCAAGTGCACGCAGTGCCACAAGCGCTTCACCGAGTTCCAGTCCTTCAGCGAGCACATTGCCAGCGAGCATCCGCATGACAAGCTCAACTATGAGGCGCATCGGGCGGCAGCTGAGGCTGCGCAGCCGGAGAGCGAGGCGGAGGAGGACGAGCAGAGCaatttgagcagcagcagtcgtcgCTATGCCAAATCTCCagccaccaacaacaacaacaacaacaataataacaacaacaacagcgagacaGCAAAGAatcaaaataacaacaacagcaacagcggcagcggcagccataGGAGCCAGCACTCGCCTCTCTGCTCACCTGTTGCAGCCACGCCCAACGATCTGTTCGCCCACCTGCCGCAtccgccgccgcagctgcccgCCCACTTGCACGCCCAGTTCATGGCCGCCGCTGCCCTGGCCATGCAGTCCGCCATTTCGCCCAgccaacagaagcagcaacagcagccgcagcatcaacagcagcagcagcagtcgccgcagctgcagcaggcgttgctgctgccgccgcctcagcccggcagcaacagcagcgtcgGCAGCAACTCCGCCTACGACCTGGACTTGAGTGCGCCCCGCTCCACCTCCAGCCCGGGCTCCACCACGGGCGACCTCGGCGCCGCCTTCCCCTGCATGCAGTGCACCGCCGCCTTCGCCAGCCgcgagcagctcgagcagcaccagctgctccACTCGCCCACGGGCCCGCAGACCACACAGAATGTGACACAGACCTGCAAAATATGCCACAAGGCCTTCGCGAACGTGTACCGCCTGCAGCGGCACATGATCAGCCATGACGAGTCGGCGCTGCTGCGCAAGTTCAAGTGCAACCAGTGCGACAAGGCGTTCAAGTTCAAGCACCACCTGAAGGAGCACGTGCGCATCCATTCCGGCGAGAAGCCCTTCGGCTGCGACAACTGCGGCAAGCGCTTCTCGCACTCGGGCAGCTTCTCCTCCCACATGACCTCCAAGAAGTGCATTAGCATGGGCCTCAAGCTCAACAACAACCGCCAGATGCTCAAGACGCTCGACAAGAACGCGAGCGCCAGACGCTCCCCCAcggatcagcagcagcagcagcagctgcagctggcgggcAAGCGGAAGCTGTCCGATCAGGTGCTGCCCAATCCCATGAACTACTTTGCCGGCGAAGTGCAAAGCCCGCCCACTGCTGTCAACGCCCCTGCGCCCTTCTACTCCAACTACAATGCCATGAACGCGGCTCTGCTGGCGTTCCCCAACGCCTTCATGGCTGCCGCGCTGGATCCGCGCATGCATCCCTACAGCATACAGCGGCTGCTGGAGCTGACTGCtgccgggcagcagcagcagcagcagcgggaggagcagctggagcaggagcacaGGGAGGAGCAGAAGCTGTATGAGACCAGCAAGGATGACGACGAGACGCCCGACGAGCCCAAGCTGGTTATGGACCTGGAGGAGTCGGAGCCCAAGCCGACGGCCAGCCCGGAATCGCCCGTGGCCGAGCCGGTGGCcatcgacgtcggcgtcgtcaAGCAGGAGCCCAGTCGCGAGCCAACGCCCCCGGACACGCCCAAGTCCATCAAAGTGGAGCACGAGGAGGAGCCGGAGGCAGCAGCCGTGGAGCAGTCGCGCGCGCAGACGCCCCAAGATCTGCGTTGCAGTCGCTGTGCCAAGCAATTCAACCATCCCACGGAGCTGGTGCAGCACGAGAAGGTGCTGTGCGGCCTCATcaaggaggagctggagcagcaataccaacaacagcaacaacaacaacagcagcagcaacaacagcagcagccgcagcagcagcagcaggcgagctTTGCTCTGCATCCCTCGGCCAGCGATGCggacgaggatgaggaggacgaggaggagccGCGCCACGACTACCacgccggcggcagcagcgacagcggcgagCGCAAGGTGCGCGTGCGCACCGCCATcaacgaggagcagcagcagcagctgaagcagcactACGCCCACAACGCGCGTCCCAGTCGCGACGAGTTCCGCCTGATCGCCGCGCGCCTGCAGCTGGATGCGCGCGTCGTCCAGGTCTGGTTCCAGAACAATCGCTCGCGCGAGCGCAAGCTCCAGAGCTATGCGAGCAATGGCGAgcccgcagccgccgccgccgctccaGCCGTGCCACAGGCGCGCGCTGGCGAGGATCAGCCGCTGGACCTGTCCGTCAAGCGGGATGCCTCGCCGCTGTACGGCGCGGCTACGTCCCAGCAGGCAGCTGTGCTGCCCGCGCCCGCCGACTTCCCGGAGGCCATGGCCATCAACCTGAGCCGCAAGCTCTCCGGGTCGGCGTCCATGTCGCCGGCCTCGCTGTCGCCCTGCTCGGGCGCCTCCTCGCTGCAGCaatcggcggcagcagctgcggccgcCGCCGCGCTCTACTTCGCGCCCCCCTCGCCGCCCAGCCTGCACGAGTCGGCGCCCAGCATGGCGACGCCGCATGGCGCAGCTGCGGCGCGCGGCCAGGCCTTCGCGGGGCTGCACGCGCCCTACATGCTGCCGCGCCTGCCCATGGAGGCGCTCTTCCAGATGCGGCCGGGCGGCGACTACGCGCCCAATCCGCTTATGAACAGTATTAAGCTGCCCGACTATCGCGGCACCAGCCTCAGCCCCGGCGGCTCGGAGAAGCGCTCGTGGCGCGACGACGACTCGCGCATCTCGCACGACGACGACTACGTCCTGGCGAGCGGCGGCCTGCTGCCGCCCAAGCCCAAGCGGGCCAAGGCCGAGACGCACGGCCACGCGGGCGACCCGGACCTGCCCTTCGTCTGCGACCAGTGCGACAAGGCGTTCGCCAAGCAGAGCTCCCTGGCGCGCCACAAGTACGAGCATTCCGGTCAGCGGCCCTACCAGTGCATGGACTGCCCCAAGGCGTTCAAGCACAAGCACCACCTGACGGAGCACAAGCGTCTGCATTCCGGCGAGAAGCCATTCCAGTGCTCCAAGTGCCTGAAGCGCTTCTCCCACTCGGGCAGCTACAGCCAGCACATGAACCACCGTTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MLSCLAPSSTRFGQEDNIIQQSMPSSTAFSMQFSSLASSLHHHQAHNKPSNVAANPELASSATANAAEDCLVKCTQCHKRFTEFQSFSEHIASEHPHDKLNYEAHRAAAEAAQPESEAEEDEQSNLSSSSRRYAKSPATNNNNNNNNNNNNSETAKNQNNNNSNSGSGSHRSQHSPLCSPVAATPNDLFAHLPHPPPQLPAHLHAQFMAAAALAMQSAISPSQQKQQQQPQHQQQQQQSPQLQQALLLPPPQPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLGAAFPCMQCTAAFASREQLEQHQLLHSPTGPQTTQNVTQTCKICHKAFANVYRLQRHMISHDESALLRKFKCNQCDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRQMLKTLDKNASARRSPTDQQQQQQLQLAGKRKLSDQVLPNPMNYFAGEVQSPPTAVNAPAPFYSNYNAMNAALLAFPNAFMAAALDPRMHPYSIQRLLELTAAGQQQQQQREEQLEQEHREEQKLYETSKDDDETPDEPKLVMDLEESEPKPTASPESPVAEPVAIDVGVVKQEPSREPTPPDTPKSIKVEHEEEPEAAAVEQSRAQTPQDLRCSRCAKQFNHPTELVQHEKVLCGLIKEELEQQYQQQQQQQQQQQQQQQPQQQQQASFALHPSASDADEDEEDEEEPRHDYHAGGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRLIAARLQLDARVVQVWFQNNRSRERKLQSYASNGEPAAAAAAPAVPQARAGEDQPLDLSVKRDASPLYGAATSQQAAVLPAPADFPEAMAINLSRKLSGSASMSPASLSPCSGASSLQQSAAAAAAAAALYFAPPSPPSLHESAPSMATPHGAAAARGQAFAGLHAPYMLPRLPMEALFQMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHDDDYVLASGGLLPPKPKRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00530857;
90% Identity: iTF_00559678;
80% Identity: iTF_00572499;