Basic Information

Insect: Drosophila pegasa
Gene Symbol: ham
Assembly: GCA_035046225.1
Location: JAWNOD010000175.1:2685661-2714294[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.6 37 4.9 0.0 2 21 367 386 366 389 0.87

2 9 0.012 0.74 10.3 1.6 1 23 396 419 396 419 0.91

3 9 1.9e-07 1.2e-05 25.4 1.7 1 23 425 448 425 448 0.96

4 9 3.6e-07 2.2e-05 24.5 1.5 1 23 454 476 454 476 0.97

5 9 9.1e-05 0.0056 17.0 3.8 1 23 482 504 482 504 0.97

6 9 0.002 0.12 12.7 2.0 2 21 512 531 511 532 0.94

7 9 7e-09 4.3e-07 29.9 1.3 1 23 1051 1073 1051 1073 0.99

8 9 3.7e-07 2.3e-05 24.5 0.9 1 23 1079 1102 1079 1102 0.97

9 9 4.7e-05 0.0029 17.8 6.8 1 23 1108 1130 1108 1130 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.6	37	4.9	0.0	2	21	367	386	366	389	0.87
2	9	0.012	0.74	10.3	1.6	1	23	396	419	396	419	0.91
3	9	1.9e-07	1.2e-05	25.4	1.7	1	23	425	448	425	448	0.96
4	9	3.6e-07	2.2e-05	24.5	1.5	1	23	454	476	454	476	0.97
5	9	9.1e-05	0.0056	17.0	3.8	1	23	482	504	482	504	0.97
6	9	0.002	0.12	12.7	2.0	2	21	512	531	511	532	0.94
7	9	7e-09	4.3e-07	29.9	1.3	1	23	1051	1073	1051	1073	0.99
8	9	3.7e-07	2.3e-05	24.5	0.9	1	23	1079	1102	1079	1102	0.97
9	9	4.7e-05	0.0029	17.8	6.8	1	23	1108	1130	1108	1130	0.98

Sequence Information

Coding Sequence: ATGCTATTCGAACGATATATTATATCAGgCTCTAACGGCGACGACTACGATCCGAGCGTCGTGcgccaccatcatcatcatcaccatcattTGGATCTCAGCAGCGGAGCGCCGGCCTTTGGTCCGCTGCCGCCGGCGCACTTAGCCTCGAGCCAGGCTCGGCCCGAGGACACGTTCGGCCGCCATCTGCCGCCGACGATATCCCCGCCACCCgcctcgctgctgcagcagcaatcgcagtcgcagtcgcagtcgcagtcgcagcagccgcagccaccgtcgctgccgccgtcgcatttgtcgctgcagttgcagcaacagcgactgcTACGCTCGCCGCCCGCTTCCGTCTCCGCCTCCGTCTCCgcctccggctccggctctggctccAGCATGGAGCACCTGTTCAACAATGGCAACGCGCAGGAGTTCCTGCTGCAGATGGCGCGCCTGCGCGACCCCTTTTGTGATCTGGACATACGTGATAACGGCGTCTACGCCAAGACCGATCTGCCCTGCGGCTCCCGCTACGGACCCTTCCCCATGCACCTCTGCCAGCAGCCCAGCGATCGCCATCTGGCCTGGGAGgtaATTGCGCGACCTTTGTTCCATGGCTGGCTGGAGCCCTCGGCGGACGTGGCCACGTGGCTGAAGAAGatccgccacgcccccctggAGGAGGCCGAAGAGGCTAATCTGCGGAATTTCATCAGCGATCGCTGCCTGTGGTACGAGACGAAGCGCGACATTGCGGCGGGCGCGGAGATCGTGGTTGAGGCTCGCTCCCGCACGCCCTACGACCTCAGCGACAGCCTgcgcaacgccagcagcagcagcagcgccggcgccggcgcaggcagcggcagtggcggcggcagcaacagcgtcgccgcagcagccgcagccgcagcagccgccgccctggcagcagccagcagcaacaacaacaacaacaacaacaacaacaatggcgatGATCGCAGCGATCGTGATAACGGCTTTTACAGCGGCGACGAACTTGCCAAGGATAAGAAAAACATATCGTTAATTAGTCAGGGCGACAACGATTTCACAGACGACGAGAACGGGTTCGACATACGCTGTGAGGTCTGTGATAATGTCTATACGGATTTAGAACGCCTGGACGATCATCTGGTGGGCGCGCATCACTTCAAACGCGGAGAATTCGCCTGCGAGCTCTGCCCCCAACACTTCTGCCATCGTCCACTGCTGATCAAGCACGGAGCGATCGCCCACAACAATATAAGGAAATATTCCTGCGAGAACTGTTCCAAGGTATTCTGCGACCCATCGAATTTACAGCGGCATATTCGCGCCTACCACGTCGGCGCTCGCAGTCATCCGTGTCCGGAGTGCGGCAAAACATTCGCCACCTCGTCCGGCTtgaagcagcaccagcacatCCACTCCTCGGTGAAGCCGTTCGCCTGCGAGGTCTGCTTCAAGGCCTACACGCAGTTCTCCAACCTCTGCCGGCACAAGCGCATGCACGCCGACTGTCGCATGCAGATCAAGTGCAAGAAGTGCAACACGAGCTTCAGCACGGTCACCTCGCTCTCCAAGCACAAGAAGTTCTGCGACAGCTCCGACAGCTtccgcagcagccagcagagtcgcctgcagcagcagcaccaccaccaccagcagcaccagcagcaccaccagcagcagcagcagcagtcgcagcaccTGTCGCATCAGCAGTCgtcgcagcagtcgcagcttcTGTTGCCGGCGGACGCACATCAGCgactcgccgccgccgccgccgccgctgccgcagccagcagcaacagcagcgaggcAGCCGCCATGGCGACGCCGCCCAACCACATGTTCACGATGCACCCGACGCCCTCCTACTTTCCGGGCTTCCCGCCCTACGCGCTGCCCAACTTCTTCACCAACTGCcggccgcagccgctgctgccgcacaTGTTCCCCAGCCCGCACCTGGGCGACATGGGGCGTGGCCTGATGGCGCCTTCGCTGGTCTCGCCGAACGCCGccttccagcagcagctgcaggcggccATGAGCCTCAAGGCGGAGTCGCCGTCGCGTCATAAGCGCGAGTCCAGCACGCCGGAGCGCAAGCCCATCAAGGCGGAGCTGCAGCCcagcgacgaggacgacgaggaggaggaggaggaggatgccAACACctacgagcagctgcagctgaagctggaggCCAGCAGGGAGTCCAGCAAGCTGAAGGCGGCGGAGTCAAAGCAGGCGGAGTCAAAGCAGCAAGAGGAGCAAGACaacgatgataatgataatgataatgataatggtgatgacaatgacaatgacaatgataatgataatgacaatgataggAAATCCATCGACATCATGAGCACGCCTCCGCCCGCCGAGCGGGAGCTGCAGGTGGACGCGGGGCAGGACAAGGGCGGCGCTGACATACTGCCGCTGGATCTGTCCATCAGTCGCAAGCGACGCAGCTCGCTGTGCACGGCCGCCACGCCCGTGCCGCTGGCCATTTCGCTGTCCAGTCGCACGTCCACGCCCAGCCtggagctggcagcagcagctgctgggcagccCCCTTTAAAGCTGGCGAAGCTCAGCTCCGGCGAATCGTCCACCTCGCACCAGTCCTTCAAGGGCAGCAGTCCCACGCCCAGTGTCAGCGCCTCGCCCGGGCccacgccctcgccctcgccgccCATCAGCACAGGCGGCGAGCTGAGCAGCATGTCCGACAGCGCAGCGTCTGCGGCCGTGGGCAGCGCGTCGGCTGCGtcggcggcgtcggcagcggcagcggcggcggctgctgctgcctcggtGATGGCCTGTCCGCGGCAGCTGCacccgcagctgctgctcgaggaGTTCTACCGCTCGCGCTTCAACACGCCACCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGCCACTCAAATCGCCGGCTGCtggcatcagcagcggcagcagctcgcgTCATCTGCCGTTTCCGCCCGAGCACAATTTCCACGAGGCGCTGCGCGCCGCCGGCCTGGCCGCCGCCGCGGCCAACGcttgcagcagcgccgccggcgtcggcgtcggcgtcggcgccACCAACGGTGGCAAGCTCAAGGATCGCTACACCTGCAAGTTCTGCGGCAAGGTCTTTCCGCGCTCCGCCAACCTGACGCGCCACCTGCGCACGCACACGGGCGAGCAGCCGTACACGTGCAAGTACTGCGATCGCGCGTTCAGCATCTCCTCGAATCTGCAGCGCCACGTGCGCAACATCCATAATAAGGAGCGCCCCTTCCGCTGCCACATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGGCACCTGAAGAAGCACGAGGCGGACGCGGGCGGCTTCGAGTACAACGACTCGCCCAGCTCGAACGAGGCGAACGACCGCGAGGAGGCCTGCTTCGACGACATACGCTCCTTCATGAAGCGCGTCTACACGCCGACGAGTCTGGGCGGCGCCGATGGGGACACCGAGGAGTATGCGGGCAGCGACGATCAGTTGTCCGTCTCGACGCGTCACTCCGTCAGCTTCGACAAGGAGCTGTTggccaatggcaacaacaataacaacaacaataacagcaacaacaacaacagcaacaacaacaacagcaacagcagcagcaacaacaacaacaacaatcagatcGCCGTGAGCACCTAG
Protein Sequence: MLFERYIISGSNGDDYDPSVVRHHHHHHHHLDLSSGAPAFGPLPPAHLASSQARPEDTFGRHLPPTISPPPASLLQQQSQSQSQSQSQQPQPPSLPPSHLSLQLQQQRLLRSPPASVSASVSASGSGSGSSMEHLFNNGNAQEFLLQMARLRDPFCDLDIRDNGVYAKTDLPCGSRYGPFPMHLCQQPSDRHLAWEVIARPLFHGWLEPSADVATWLKKIRHAPLEEAEEANLRNFISDRCLWYETKRDIAAGAEIVVEARSRTPYDLSDSLRNASSSSSAGAGAGSGSGGGSNSVAAAAAAAAAAALAAASSNNNNNNNNNNGDDRSDRDNGFYSGDELAKDKKNISLISQGDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFACELCPQHFCHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCKKCNTSFSTVTSLSKHKKFCDSSDSFRSSQQSRLQQQHHHHQQHQQHHQQQQQQSQHLSHQQSSQQSQLLLPADAHQRLAAAAAAAAAASSNSSEAAAMATPPNHMFTMHPTPSYFPGFPPYALPNFFTNCRPQPLLPHMFPSPHLGDMGRGLMAPSLVSPNAAFQQQLQAAMSLKAESPSRHKRESSTPERKPIKAELQPSDEDDEEEEEEDANTYEQLQLKLEASRESSKLKAAESKQAESKQQEEQDNDDNDNDNDNGDDNDNDNDNDNDNDRKSIDIMSTPPPAERELQVDAGQDKGGADILPLDLSISRKRRSSLCTAATPVPLAISLSSRTSTPSLELAAAAAGQPPLKLAKLSSGESSTSHQSFKGSSPTPSVSASPGPTPSPSPPISTGGELSSMSDSAASAAVGSASAASAASAAAAAAAAAASVMACPRQLHPQLLLEEFYRSRFNTPPFHFLGQMGGRPGFEPLKSPAAGISSGSSSRHLPFPPEHNFHEALRAAGLAAAAANACSSAAGVGVGVGATNGGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHMCDRCFGQQTNLDRHLKKHEADAGGFEYNDSPSSNEANDREEACFDDIRSFMKRVYTPTSLGGADGDTEEYAGSDDQLSVSTRHSVSFDKELLANGNNNNNNNNSNNNNSNNNNSNSSSNNNNNNQIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00568407;
90% Identity: -
80% Identity: -