Basic Information

Insect: Drosophila pegasa
Gene Symbol: su(Hw)
Assembly: GCA_035046225.1
Location: JAWNOD010000398.1:592921-595979[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00065 0.04 14.3 2.2 1 20 224 243 224 245 0.94

2 12 2.7e-06 0.00017 21.7 0.4 3 23 296 317 294 317 0.93

3 12 0.0059 0.36 11.2 0.2 1 23 323 345 323 345 0.97

4 12 7.3e-07 4.5e-05 23.5 2.5 1 21 352 372 352 373 0.95

5 12 3.2e-06 0.0002 21.5 0.6 2 23 385 406 384 406 0.96

6 12 0.0001 0.0063 16.8 5.3 1 23 417 439 417 439 0.99

7 12 7.9e-05 0.0049 17.1 0.9 1 23 445 467 445 467 0.97

8 12 1.6e-05 0.00098 19.3 0.8 1 23 473 495 473 495 0.99

9 12 1.5e-06 9e-05 22.6 3.0 1 23 501 523 501 523 0.98

10 12 0.0032 0.19 12.1 1.4 1 23 527 549 527 549 0.97

11 12 3.6e-05 0.0022 18.2 0.2 1 21 557 577 557 581 0.92

12 12 5.6e-05 0.0034 17.6 0.3 3 23 601 622 599 622 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00065	0.04	14.3	2.2	1	20	224	243	224	245	0.94
2	12	2.7e-06	0.00017	21.7	0.4	3	23	296	317	294	317	0.93
3	12	0.0059	0.36	11.2	0.2	1	23	323	345	323	345	0.97
4	12	7.3e-07	4.5e-05	23.5	2.5	1	21	352	372	352	373	0.95
5	12	3.2e-06	0.0002	21.5	0.6	2	23	385	406	384	406	0.96
6	12	0.0001	0.0063	16.8	5.3	1	23	417	439	417	439	0.99
7	12	7.9e-05	0.0049	17.1	0.9	1	23	445	467	445	467	0.97
8	12	1.6e-05	0.00098	19.3	0.8	1	23	473	495	473	495	0.99
9	12	1.5e-06	9e-05	22.6	3.0	1	23	501	523	501	523	0.98
10	12	0.0032	0.19	12.1	1.4	1	23	527	549	527	549	0.97
11	12	3.6e-05	0.0022	18.2	0.2	1	21	557	577	557	581	0.92
12	12	5.6e-05	0.0034	17.6	0.3	3	23	601	622	599	622	0.96

Sequence Information

Coding Sequence: ATGAGCGCCAGCAAGGACGCCGCTGCGGCAGCCCCAGCCAGCAACAAGGAGGCCAGCACACCCATCATCCGAGTAATGGCCATGGACAAAATGGTTTCGCCGAAGACGAAGCGCACTGGCACACGCATGAAGCTGCTGAACGATGTGGCCGCAAAGGCTGCTCGCCCCAAGCAGGAGAAGCGCACCAGCATCAAGATACTCAACAACGACGAAGCCCAGAGCAGCTCGAAGGGCGGCGACAAACGTGCCACGCCCAAGACGGTTAGCCCCGGCGTTAAGATATTGAACGAGAAGCGAATTGTGCCCTCGGCCGCAGCAATGGAGACGGCCAAGATAAAGACATCGcccagcaagaagaagaaaatggaTCACTATGTGCTGCAGGCCATCAAGAGTGAGAACAGCAAAGCGGACAACACGACCAGCGTGGTGGTGGTCGAGGACGAAGACACCATTGACTTCATACTAGCCGACGAAGACGTCGAGCTCGGAGATGCTGCCAAAGAGAACGGCGAGGAGTTCGTAGTATCTGGCGTcgaggacgacgatgacgacgacgacgaggatgatGAGGACGACGATGATGGGCCAGGAGGAGGTGCTGGCGCTGCAAAGCGCAAgagtggcaacggcaacaacaacaacagcgagctCAAGGAGATGGTCGAGCACGTGTGCGGCAAGTGCTACAAGACATTCCGTCGCGTCAAGAGTCTGAAGAAGCATTTGGAGTTCTGTCGCTACGACAGCGGCTATCATCTGCGCAAGGCGGAAATGCTGAAGAATCTGGACAAGATTGAACGCGACGCCGTGGTCATGGAGAAAAAGGAcatctgcttctgctgcagcgAGAGCTACGATACCTTTCATCTGGGCCACATCAACTGCCCCGACTGCCCCAAGTCGTTCAAAACACAGACGAGCTACGAGCGTCACATTTTCATCACGCACTCCGAGTTCAACGACTATCCATGCTCCATTTGCAATGCCAAGCTGCGCAGTTCGGCGCTGCTGAAGctgcacgagcagcagcatcagtccAGGGGCAAGCCCTTCGCCTGCAAGATCTGCGGCAAGGACTTTACGCGCTCGTATCATCTGAAGCGCCATCAGAAGTATTCGTCGTGCTCGGCCAACGAGAACGACACCATGAGCTGCAAGGTGTGCGATCGCGTCTTCTATCGCTTGGACAACTTGCGCGCCCATCTGAAGCAGCATCTGGGCACCCAGGTGGTGAAGAAGCCGGAGTACATGTGTCACGTGTGCAAGAACTGCTTCTACAGTCTGTCCACACTCAACATccacatacgcacgcacacgggCGAGAAGCCGTTCGATTGCGATCTGTGTGACAAGAAGTTTTCGGCTTTGGTGGCGCTCAAGAAACATCGTCGTTATCATACTGGCGAGAAACCCTACACCTGCACAGTGTGCAGTCAATCCTTTGCCGTGAAGGAGGTACTCAACCGCCACATGAAGCGGCACACGGGCGAGCGTCCGCACAAGTGCAACGAGTGCGGCAAGAGCTTCATACAGGCCACACAGCTGCGCACGCATTCCAAGACGCATCTGCGTCCCTACTCCTGCTCCTtgtgcattcaaaagtttaaGACCGAGAAACAACTCGAGCGCCATGTCAAGGAGCATTCGCGCCAGAAGCGCCCCTCGTTTGCCTGTTCGGAGTGCACGCGTAGCTTCCGCACCAGCGCACTGCTCAAGGAACACATGGACGCTGGCGATCATTCGCCTGTTAAGCCTACCCGCGCTAAGCGTTCGGCCAAGGTGATCGAGCGCACGGACTGTGCGATTTGTGACAAGAACTTCGACAGCACCGACACGCTCCGGAATCATATACGCAACGTGCACGAGTGCGATCCGGATGATATTTTCGGCACTGAGCCGCCAGCCAGACGCAAGGCTACCAAAAAGGCCGTCGTGGCGGTAGAAGATGAAGAGGAGTCGAATgaggagaaggagcaggaTAAGGAAACGCCGGCTGTCAACACATCAGCTGGTTCGCTCATCTCCAGCAAAACAGATGACAATGGCGTCGTGGTGCGCGAGTTTTTGGTGGACGAGGGCGATGGCAGTGCGCAGACCATTGTGCTCGAGAACGAGGTCTACACCATTTTGCCCTTGGAGGGTGCAGCCAGCACAGCCGAGCCGACGGCCGAAGAGGACGACGACGTCAAGGGCGATTCGAAGGAGAAGTCACGGTCGGCTGTGTCACCAGTCGTCAAGAAGGAGCAGCGCAAGTCGTTGGCCGCCAGCTTGGCCGCTGCTATCGCCGACAATCTGGATGAGCCGTCGAGTGATGATGAGTTCAACGGCGAGGTGCTCACTGAGGAGGATGTCAAACTGAAGGAGAACGTAGCGAAGCTGATCGATATGCTGGTCGATCCGCAGACACTCAAGAAGTACAACTGGCCCAACAGCTCCGAGGAGTCGGTGCTGTGCAAGGTCATCGAGAATTGTGGCCACGATCTGGCCAAGGGCAGCGAGGCCTACGCCGAGTTGGACTATGGCAGTCGCATGCGTGAATACTGCAAACTCCTCTTCACCGTGGTCATCCACAACGATTCCATAAAGACGCTGCTCAACAACTTTCCCATCGACGACGTTATTGACTATGTGCTGGGCGATGAGGACCAGGACCAGGATCAGGACGCAGACAAGggcaaggagaaggagaatgaCGGAGAGAAGTCGGATACGGACACTAGACAGGATGAAGCTGAAGCTTAG
Protein Sequence: MSASKDAAAAAPASNKEASTPIIRVMAMDKMVSPKTKRTGTRMKLLNDVAAKAARPKQEKRTSIKILNNDEAQSSSKGGDKRATPKTVSPGVKILNEKRIVPSAAAMETAKIKTSPSKKKKMDHYVLQAIKSENSKADNTTSVVVVEDEDTIDFILADEDVELGDAAKENGEEFVVSGVEDDDDDDDEDDEDDDDGPGGGAGAAKRKSGNGNNNNSELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKAEMLKNLDKIERDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSSALLKLHEQQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYSCSLCIQKFKTEKQLERHVKEHSRQKRPSFACSECTRSFRTSALLKEHMDAGDHSPVKPTRAKRSAKVIERTDCAICDKNFDSTDTLRNHIRNVHECDPDDIFGTEPPARRKATKKAVVAVEDEEESNEEKEQDKETPAVNTSAGSLISSKTDDNGVVVREFLVDEGDGSAQTIVLENEVYTILPLEGAASTAEPTAEEDDDVKGDSKEKSRSAVSPVVKKEQRKSLAASLAAAIADNLDEPSSDDEFNGEVLTEEDVKLKENVAKLIDMLVDPQTLKKYNWPNSSEESVLCKVIENCGHDLAKGSEAYAELDYGSRMREYCKLLFTVVIHNDSIKTLLNNFPIDDVIDYVLGDEDQDQDQDADKGKEKENDGEKSDTDTRQDEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00495995;
90% Identity: iTF_00502661;
80% Identity: -