Dpau000272.1
Basic Information
- Insect
- Drosophila paulistorum
- Gene Symbol
- -
- Assembly
- GCA_018152135.1
- Location
- JAECXG010000821.1:17039515-17041209[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 1.6 1.2e+02 3.5 0.7 11 23 190 202 188 203 0.83 2 10 0.15 12 6.7 4.8 6 23 212 229 203 229 0.91 3 10 0.0021 0.16 12.6 1.0 1 23 235 258 235 258 0.97 4 10 0.00011 0.0087 16.6 2.4 1 23 266 288 266 288 0.98 5 10 0.0005 0.039 14.5 3.2 2 23 295 317 294 317 0.97 6 10 5e-05 0.0039 17.7 0.7 1 23 324 347 324 347 0.97 7 10 0.0054 0.42 11.3 0.4 2 23 357 378 356 378 0.97 8 10 0.008 0.62 10.7 1.0 1 23 387 409 387 410 0.96 9 10 0.0027 0.21 12.2 1.7 1 23 415 437 415 437 0.97 10 10 2.9e-05 0.0023 18.4 3.7 1 23 443 466 443 466 0.97
Sequence Information
- Coding Sequence
- ATGGCTAAGAAAGTGTGCCGACTTTGTTTGGAGGAAGGCCTTACGGAGGTCGCCATAGGTGAACTAGTTAAATTTATAGAAGAGCATTTCAAACTGAAGATGGAGAACAGCGAAGTCAATCCCATGCAACAATTCATATGTCATAGCTGCTGGAAACAAGTTGAAGATTTTCGATGTTTTTGTCTCATGATAGAAGAGAAGCAAAAATTGTATCAAGAGCAACTACAATTAAAGGAAGAAACTAATCCTGAATCGGAATCGGAGTCACTATTCGAACCTCAAATTGATGTAGAACCTTTGCCTAATATTAGTGAAGTCAATATAATTGACGATGAAACTAACCCAATTAACAAGAAGAGCAAGGAGAAAAAGGCCAGTGCAGTAAGGGCGCTACGACTTGGCCTTCGATTGCGTTCCACAAAAGTAAAGGATAAACCCATTGCCAAGCGTAAACCAGCCCCAGATCCAGATAGAAATGCGGATTCGAATCACGAAAACGACCTTTTAATAGCTACACATGGACGACTCGAATGTGTTTTGTGCGTGGAGTCGCCGTTTCCTTCTCTGACCACCTTTGCTGATCTAAAGCGACATTATCGAGCACATCATCAGTGCGACGGATATGTGGAATGCTGCCATAAGCGATATAAAAAGAGGTCACTTTATGTGGATCATCTTCGTATGCACAAGGATCCCAGCTACTTTAGATGCAAAACATGCGGCAAACAATTGGTCAGTCGAATTAGCTATGATGTTCATATGCTGCGATTTCATTCTAAGGAGGAATCTTTGAGATTTTCCTGTAGTCAATGTACAAAACGTTTTAGCAAACGCTTTCTATTGGAAATACATTCACGTGTTCATTGCAGTGACAAGACGGATCAATGTGTACATTGCCATAGATACTTTGGCTCTTCTGTCGCTCTGCGCTCCCATATCCGCCGCTTCCATGATCCAAACTTTGTGCCCTTCATATGTGAGTCGTGTGGCTCCGAGTTTAAGACAAAACAAAATTTATTAGTGCACAAACGTACAGTGCATCTGGAGGGACCGCAATTACCCGAGGTTCAATGCGAAGTTTGCCAGAAATGGCTTCGAGACGAGAACAGTCTCCGGAAGCATATGTACATGCATGTGGATGCTGCTTCGTCCAAGACCTATAAGTGCGACCAATGTGGACAGGAGAAGGACTCACGTGTTAAATTAGCTGCCCACATTCGGTATCATCATCCCAAAGAGTATCACAAGTGTTCGGTATGCGACAAACAGTTCAAAAATGTGCGAGGAAGGGATGAGCATATGGCTACCCACACGGGACGTGATCTCTATGAATGTGCGTTCTGCGATCGCACATTTAAAAATTCGGGCAATATGCATAAGCATCGGAGGCAAATGCATGTCAGCGAGTTGGCAGCACTGCAGGAACAAAAGACAATGCGGCCCAGCAAGCGAAATGCTATGGCGAAGCAGGAAAATTTAGAATTAAAATCCTCTTAG
- Protein Sequence
- MAKKVCRLCLEEGLTEVAIGELVKFIEEHFKLKMENSEVNPMQQFICHSCWKQVEDFRCFCLMIEEKQKLYQEQLQLKEETNPESESESLFEPQIDVEPLPNISEVNIIDDETNPINKKSKEKKASAVRALRLGLRLRSTKVKDKPIAKRKPAPDPDRNADSNHENDLLIATHGRLECVLCVESPFPSLTTFADLKRHYRAHHQCDGYVECCHKRYKKRSLYVDHLRMHKDPSYFRCKTCGKQLVSRISYDVHMLRFHSKEESLRFSCSQCTKRFSKRFLLEIHSRVHCSDKTDQCVHCHRYFGSSVALRSHIRRFHDPNFVPFICESCGSEFKTKQNLLVHKRTVHLEGPQLPEVQCEVCQKWLRDENSLRKHMYMHVDAASSKTYKCDQCGQEKDSRVKLAAHIRYHHPKEYHKCSVCDKQFKNVRGRDEHMATHTGRDLYECAFCDRTFKNSGNMHKHRRQMHVSELAALQEQKTMRPSKRNAMAKQENLELKSS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00523943;
- 90% Identity
- iTF_00503513;
- 80% Identity
- -