Basic Information

Insect: Drosophila paulistorum
Gene Symbol: grau
Assembly: GCA_018152135.1
Location: JAECXG010000822.1:25770107-25772180[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2e-06 0.00015 22.1 0.3 2 23 308 329 308 330 0.94

2 8 2e-06 0.00016 22.0 0.9 1 23 338 360 338 360 0.96

3 8 0.087 6.7 7.5 1.5 1 23 368 393 368 393 0.90

4 8 0.00088 0.068 13.7 0.9 2 23 399 420 399 420 0.97

5 8 0.062 4.8 7.9 0.2 2 23 429 452 428 452 0.86

6 8 8.9e-05 0.0069 16.9 2.0 1 23 459 482 459 482 0.96

7 8 7.1e-06 0.00055 20.3 0.8 1 23 487 509 487 509 0.97

8 8 7e-05 0.0055 17.2 3.8 1 23 515 538 515 538 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2e-06	0.00015	22.1	0.3	2	23	308	329	308	330	0.94
2	8	2e-06	0.00016	22.0	0.9	1	23	338	360	338	360	0.96
3	8	0.087	6.7	7.5	1.5	1	23	368	393	368	393	0.90
4	8	0.00088	0.068	13.7	0.9	2	23	399	420	399	420	0.97
5	8	0.062	4.8	7.9	0.2	2	23	429	452	428	452	0.86
6	8	8.9e-05	0.0069	16.9	2.0	1	23	459	482	459	482	0.96
7	8	7.1e-06	0.00055	20.3	0.8	1	23	487	509	487	509	0.97
8	8	7e-05	0.0055	17.2	3.8	1	23	515	538	515	538	0.98

Sequence Information

Coding Sequence: ATGGACATCTGTCGCCTGTGCTTGAGGGGAGTACGTGGGTCCCAGATGTGCCTACAGATCTTTGATCCCAGTTCTGTGGACAACAAAGTGGCTGCAGTTCTACGCCAGCATTTTTGGTTTGATGTTCAGCCCAACGATGAAATCTCGAAAGTAATCTGTAATGTCTGCTGGACTCAGGTGTCGGAATTTCACCAATTCTATGTTTCCATACAAGAGGCTCAGGTTATTTATGCCACAACTTCAAAATTTAAGGAAGACCCAGAAATGGCCAGTGCCAATTGGCCAGAGGAGGTAATGATGCCAGCGGATGTTTTGGCTGTGGACAATGATATCAACATAAATGTGAATCCTCTGGATGAATTGGATGTGAAGCCGGCTCCAGCAAAACAAGAAGACAACCGAATGGATATTAAGAAAGAGAGGGATTCCCCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAGATTTAATTATCACACGAAGTGGACGCAAAAGAAAGAGGGAACCCGTAAAAACTCAATCGAAAAGACCTCTTCTCAATCAAAAGGATGCGTCAAAGGGCAAAACAAAAGGTCAAAAACGTGAGCCCGGAAGGAGAACCTTTAAAACTCTGCAAAGGTGGCCACCATTCTGCAAAGAGGACGAGGAGCTCATTAAACGGTATATTGTAATGGGTTGCGAGCTATGCATATTTTTGGCCCAAGATTTTGATGGCATCCGCGAACACTTTAAAGAGAAACATCCAGATGAGCGACCCTACATCAAATGCTGCGGTCGAAAGCTAAATAAACGTTGCCTGATCCAGGAGCATGCCCGCCGTCATGAGAATCCCGAGTGCAAGGACTGCGGCAAGGTTTTTGCCAATTCAAGTGTATTACGTGCTCATTGGCTGGTCCATCATGTTCCCGATGAGGAGTGCGATTTCCAGTGCGAGGATTGTGGCAAACGTTTCTCACGCCGCAACCTTCTGGAGCTGCACAAGGGCTCTCATGTGCCCGCGAATGAACGAAAATTTATTTGTCCAGAATGTCCCAAACACAATGCCTTTGCGACCGAGTATCATATGCAGGTCCACATAAGCATGCAGCATCGGAAAGCGGCCAATGTCTGTCATGTTTGTGGCAAAAAGATTAAGGATAAAGCTGTCTTTGAGAAGCACGTTCGACTGCATTTTGAGGAAAGTGGACCACGTATAAAATGCCCCCGTCCCGATTGTGAGAGTTGGCTAAAAGATGAGGATAACCTCAAGCAACATTTGCGGCGTCACAATGACGAAGGCAAACTCTTCATTTGCTCTGAGTGCGGCAAGAGTTGCAAGAATTCTCGGGCTCTAATCGGACACAAACGCTACTCCCACTCTAATGTCATATATACCTGCGAACAGTGCGGCAAGACTTTCAAGAAGGACATTAGTCTTAAGGAACACATGGCCCAGCATACGGGCGAACCACTGTATAAATGTCCTTTCTGTCCACGCACTTTTAACTCAAATGCGAATATGCATTCGCATAAGAAGAAAATGCATCCAGTTGAGTGGGATATATGGCGGAAAACAAAAACGGGAAGTTCGCAAAAAATACTTCCTAGCGCCCAGGTGGCTCAAATGTTCCGAGAAGATGCCTCCGGCCCCGCCGAATCAACCGACCCTGCCATTGTCAATGACTACACAGCATAG
Protein Sequence: MDICRLCLRGVRGSQMCLQIFDPSSVDNKVAAVLRQHFWFDVQPNDEISKVICNVCWTQVSEFHQFYVSIQEAQVIYATTSKFKEDPEMASANWPEEVMMPADVLAVDNDININVNPLDELDVKPAPAKQEDNRMDIKKERDSPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIDLIITRSGRKRKREPVKTQSKRPLLNQKDASKGKTKGQKREPGRRTFKTLQRWPPFCKEDEELIKRYIVMGCELCIFLAQDFDGIREHFKEKHPDERPYIKCCGRKLNKRCLIQEHARRHENPECKDCGKVFANSSVLRAHWLVHHVPDEECDFQCEDCGKRFSRRNLLELHKGSHVPANERKFICPECPKHNAFATEYHMQVHISMQHRKAANVCHVCGKKIKDKAVFEKHVRLHFEESGPRIKCPRPDCESWLKDEDNLKQHLRRHNDEGKLFICSECGKSCKNSRALIGHKRYSHSNVIYTCEQCGKTFKKDISLKEHMAQHTGEPLYKCPFCPRTFNSNANMHSHKKKMHPVEWDIWRKTKTGSSQKILPSAQVAQMFREDASGPAESTDPAIVNDYTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00555314;
90% Identity: iTF_00618634;
80% Identity: -