Basic Information

Insect: Drosophila paulistorum
Gene Symbol: ken1
Assembly: GCA_018152135.1
Location: JAECXG010000606.1:15595278-15598080[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0003 0.023 15.2 2.4 2 23 232 253 231 253 0.96

2 12 0.013 1 10.1 0.3 1 23 259 284 259 284 0.92

3 12 0.086 6.7 7.5 0.1 3 23 293 316 291 316 0.92

4 12 0.0033 0.26 11.9 1.8 2 23 329 350 328 350 0.96

5 12 1e-05 0.0008 19.8 0.6 1 23 357 379 357 379 0.98

6 12 0.0026 0.2 12.3 0.2 1 23 385 407 385 407 0.98

7 12 0.02 1.5 9.5 2.1 1 23 413 436 413 436 0.97

8 12 0.011 0.85 10.3 4.0 1 23 442 464 442 464 0.96

9 12 0.00093 0.072 13.7 2.9 2 23 471 492 470 492 0.96

10 12 0.00012 0.0091 16.5 1.1 3 23 598 619 596 619 0.95

11 12 0.0033 0.25 12.0 1.1 1 19 625 643 625 647 0.95

12 12 2.2e-05 0.0017 18.8 0.9 1 23 653 675 653 675 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0003	0.023	15.2	2.4	2	23	232	253	231	253	0.96
2	12	0.013	1	10.1	0.3	1	23	259	284	259	284	0.92
3	12	0.086	6.7	7.5	0.1	3	23	293	316	291	316	0.92
4	12	0.0033	0.26	11.9	1.8	2	23	329	350	328	350	0.96
5	12	1e-05	0.0008	19.8	0.6	1	23	357	379	357	379	0.98
6	12	0.0026	0.2	12.3	0.2	1	23	385	407	385	407	0.98
7	12	0.02	1.5	9.5	2.1	1	23	413	436	413	436	0.97
8	12	0.011	0.85	10.3	4.0	1	23	442	464	442	464	0.96
9	12	0.00093	0.072	13.7	2.9	2	23	471	492	470	492	0.96
10	12	0.00012	0.0091	16.5	1.1	3	23	598	619	596	619	0.95
11	12	0.0033	0.25	12.0	1.1	1	19	625	643	625	647	0.95
12	12	2.2e-05	0.0017	18.8	0.9	1	23	653	675	653	675	0.98

Sequence Information

Coding Sequence: ATGAGCCCCAGTGAGCAAGAGCCGTATCCGGTTAACTCATTATGTCGGATTTGCTTAAACTATTTGGGTCTCAGCCCTGGATTATCAACATCCTCTGGATCAGGACGCAGCACTTCTGCAGCAGGAGCTGTCCACGATTTGTTTTCAGATTTCGAATTGGCTAAGAAACTTTCTGCATGTACGGGAGTACACGTGGAGCAGGAAGATGGTCTGCCGCGTCTTTTATGCTATGGTTGCTTCGACCGATTAAATGATGTGAATGAATTCCAACGACTCTGCTTGAATTCCAGAAAGAAATTCAAGGAAATGGTGGCCAACAATCGAATTATTCGTATTGGATTCTTCGGCGCGGAAGAGGAGCCTGAAAAAGATGAACAGGAGCCGGAGGAGAATGAGGGAGAGGAGCCTTTGGCGTCCAATTTTGATCCTTTGATGAATCATAAAATGGAAATAATTGAGAATGAAGAAGAGGTTATTAAACTACTGGAAACTGTGGACAAGGATGTGGTTGTAAACGAGACTGCGGCCGTAAAAGACAGAGGCGAAGAGGAGGAGGAAAATCAGCAGGAAGAGGAAGAGCATCAGGAGGACGAGGAGGATCAAAGCTCTGATGACGATTTACCTTTGGCTCACCGTTTGGAGGAGGCGAAACAATCAACAAAGCGCCAAAGGTTTCCCCTTGCTCGCCTCATTCCCTGTCCGATTTGCCAACAGAAATTCAAAAAGCAATCAAAATTCGATGAACATATGAAACATCACAACGATCTCCTGCCATTTCAGTGCTCAGAGCAATCCTGCAAAAAGGGATTCACCACAATGGGTGCATTGCGCCTTCACGTAGACTATGCCCACACCAAGAAGTCACCCGAAATTCCGTGTTCAGTGGAAAATTGTAAACTACTATTTCCCCGCCTACGTCTGCTCACCATCCACCTGAAAAAGGTTCACAACTTGTCACGTTCGATCCCGCCTCGAGTAGAGCAGCCGTGCCGGGAATGTGGTCAAATCTTTCGCTGTCAAGTGGCCCTCAAGAAGCATATGTACAAGCATACGGGCGAGGAGTTACCCTACCCGTGTAACATTTGCGGCAAAGGATTTCACATCAATTCAGCCCTCAAGAATCATCTCCTTCGGCATGCGGGGATCAAGAACTATGTGTGCCCCTACTGTGGTGTCGGGAAGACCACACGGCAAGAATGGAGCAAACATATGCTGACCCACACACAGGAGAAGCAATTCAAATGTGAAATCTGTCAACATGCCACCCACACGAAACGTGCCCTCGATAATCACGTCAAGATTGTCCACGAGAAGGTACGCAATTTCGCCTGTCAGTATTGTGGCAAGACCTTTGGTAAATCGCATGCCTGCAAAATCCATGAGATGACCCACACAGGAGAGAAGCGTTGCGAATGCAAGGTCTGTGGTAAGAAGTTCCTTTACACTGAAAGTCTGACAAAACATTTGAAAATCCATGAGAAAAGTGTGGAAAGGGCATTGGAAACGTATCGCCAAAGGCAGGAGGAGAATGGAGCAGATCCGACACAAGTGGATGCTAAGGATCTACTTAAAGTTTGTGCCGAATCTGTAGCCACCATACCAAGAGATCCGAGACGTGTTGAACGTGTGGATATGGCCCAACTGGCTGGCACTGTTATCAATCCCATATCCACAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCTCCACCACCGCCGCCCTCTAAATTCATACAAAAGGAAGGAATGCATCTGTGTCCTGGTTGTAATCAAGGATTTAATAATCTCGGCAACATGAAACGTCACTATAAAAGTGTTCACGAAAAGGTCAAAGATTTCGAATGCCGCTTCTGTTCGCGCCGATTCGCCAACTCGCAATCACTGAAGCAACACGAATGGATCCATACGGGCGAGAAACCCTATGCCTGCAAGACATGTGGGAATCATTTTCGTCAAGAGGCCGCCCTCATTCGCCATCAAAAAGTGCATGAGGAGAAACCACCAAAACCCACCAAATTGCCCAAAGAGATTACAGAAAAGGTACGCGAAAAGGAAATCCAGAAATGTGAACGTAAACGTAAAGTGGAAGCCCTGCGTCAAGAGATAGCCGAAGTGGCCAAAGCGGAACTCAAAGATTTGGCCAAACAAAAGGTCAAGGAGAAGCAACTCAATTCCTACGAGCAATACAAACAAGCAGCGGCAGCGAAAGCAGACGCAGATGCTGCTACTCCAAGTTGA
Protein Sequence: MSPSEQEPYPVNSLCRICLNYLGLSPGLSTSSGSGRSTSAAGAVHDLFSDFELAKKLSACTGVHVEQEDGLPRLLCYGCFDRLNDVNEFQRLCLNSRKKFKEMVANNRIIRIGFFGAEEEPEKDEQEPEENEGEEPLASNFDPLMNHKMEIIENEEEVIKLLETVDKDVVVNETAAVKDRGEEEEENQQEEEEHQEDEEDQSSDDDLPLAHRLEEAKQSTKRQRFPLARLIPCPICQQKFKKQSKFDEHMKHHNDLLPFQCSEQSCKKGFTTMGALRLHVDYAHTKKSPEIPCSVENCKLLFPRLRLLTIHLKKVHNLSRSIPPRVEQPCRECGQIFRCQVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHMLTHTQEKQFKCEICQHATHTKRALDNHVKIVHEKVRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQEENGADPTQVDAKDLLKVCAESVATIPRDPRRVERVDMAQLAGTVINPISTXXXXXXXXXXXXXXXXXXXXXXPPPPPPSKFIQKEGMHLCPGCNQGFNNLGNMKRHYKSVHEKVKDFECRFCSRRFANSQSLKQHEWIHTGEKPYACKTCGNHFRQEAALIRHQKVHEEKPPKPTKLPKEITEKVREKEIQKCERKRKVEALRQEIAEVAKAELKDLAKQKVKEKQLNSYEQYKQAAAAKADADAATPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612291;
90% Identity: iTF_00618601;
80% Identity: -