Dpau001268.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila paulistorum
Gene Symbol
-
Assembly
GCA_018152135.1
Location
JAECXG010000821.1:10813713-10816560[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 3 2.3e+02 2.6 1.2 2 23 122 144 121 144 0.93
2 13 0.0031 0.24 12.0 2.7 1 23 155 178 155 178 0.97
3 13 3e-07 2.3e-05 24.7 2.5 2 23 185 207 184 207 0.96
4 13 0.01 0.79 10.4 9.1 2 23 441 462 441 462 0.97
5 13 1.1e-06 8.7e-05 22.9 2.8 1 23 468 491 468 491 0.96
6 13 0.00024 0.019 15.5 0.6 1 23 496 519 496 519 0.96
7 13 5.8e-05 0.0045 17.5 5.5 1 23 536 558 536 558 0.96
8 13 0.00045 0.035 14.7 1.2 1 23 563 585 563 585 0.98
9 13 3e-05 0.0024 18.3 1.7 1 23 591 613 591 613 0.95
10 13 2.2e-05 0.0017 18.8 0.7 1 23 619 641 619 641 0.98
11 13 3.2e-07 2.4e-05 24.6 2.7 3 23 649 669 648 669 0.99
12 13 2.3e-08 1.8e-06 28.2 1.1 1 23 675 697 675 697 0.99
13 13 0.35 27 5.6 3.4 1 19 702 720 702 725 0.89

Sequence Information

Coding Sequence
ATGGCCACCACAACCAGCGGTAACGGTAAGGCCAATATTGAACGCCTATGCCGTATTTGCCTGCGTCAGGTGGGCGAGGAGCAGCAGTTTCACTTCATCTACGACGAAACCCCCATGGAGCAGGGAGCCAATTTGGTTGAAATACTCAACGCCTGCACGAGCTATATGTGCGAACGCTTGGAGGATGCACCTGCCAAAATGCCACATCACATTTGTGAGGAATGCCTTAAGGCAGCCTGCCAAGCTTATCGCTTTAAGCGTGAGGCAGAGAAATCCTATTGCTCTCTTATGTCGTTGCTGGGCCTGGAGCCGGCAATCAAACACAATGAAGTGAGTACACAGACGGATCAGGTGGCTCTCTTGCCATGTGAGATGTGTCACGATAAGTTCCTTAACAGCCTGGAGCTGCGATTGCATAGAAATCGTGAGCACAGCGGCCAAAAGGGATCACCTGCGGAGGAATTCAAATGCAAATTCTGTCCCCAGCAGTTCCAAAAGTTGCGCCAACTGCGCAGCCATTTGTCGCGCATCCATGACCAAGTGGACCGGGTTCAATGTAACTTATGCGATCGAGCCTTTAGTCGGCGAGATCATTTGCAGCGGCACATGAAGAATATGCACAAATCACACAAATCCGAGGAGGAGGAGCAACCAATAGACCCCGATGGACCAGATGAGCTGGAGTCCGTTGAGGTCTTGCTGGATGACGTTGCCGTGGGGGAGGAGGAAGGCGAGTTGGGTAATGATCAGTGCAATACGAATCCCATTTCGAGTAATGAAGAGTCTGACGACGACAATGATGAGGCGAAAAAGTCACTTTGGCTTAACATTAAACCAGAGCCTTGTCTGGAAGCAGAGCCAGAGGCGGAACAAGTAAATGTCAAAGCGACTAAAAGACGTAGGAAAAAAGCAGAACAGGCAGAAGCCTTTGAGACCACAGAGGCAGAGGTCAAGGCTGAGCCATTGGCCCATGTTGAGTCAGTTTTGCACATTAAACAGGAAAGTCAAATGGGTCCCAGCGAGGAAGAGAATGCCACTGTCCAAATACCAGCAAAAAGTCTACCCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTCAAGCTAAGCCCAAAGTGGAGATCGTTCGAGAATATCTACAGAAGTCAAAGAAACCCAAACGCCGGCGTCGCCGCAATCGTGATGAAAGTGAACCCAATCCTGAAAATCGTTGCGATGTCTGTCAACGAACATTTTCCCGCCATTGTCATTTACTGCGACACAAGCTCTCCCATCTGGAAAAGAAACCGCACAGTTGTCCCCATTGTCCGAAGGCCTTTGCCCGAAGCGATCACTTGAAGGCCCATGTCCAAAGTCTGCACAGTAGTAAGGAGCACAAATGCGAATTGTGCCAGGCGGCCTTTGCCCGTTCAGAAGCTTTGGAGCGCCACAAATTGAGTCGACACAACGGCGTCGGGGTGCCAGAGGGCAGTGAGCTAAAACATCAGCTGGAACACACCTGTGAATACTGTTCAAAGCGTTTCTCCAGTAAGACATATTTGCGAAAGCATACACTTCTACACACCGATTTCCTGTATGCCTGTAAGAGCTGTGAAGAGACCTTTAAGGAGCGCCAGCAATTGCGGGAGCACGAGAAGACCCATACGGGTCAAAGGAATTTCCTCTGTTGCATTTGTGGTGATAGTTTTGCACGTAACGATTATCTGCGGGTTCACATGCGTCGGCATAATGGTGAAAAGCCATACAAGTGTCGTTATTGCGTCAAGGCTTTTCCTCGAGCCACCGATCTCAAGGTCCATGAGCGCTATCACACTGGCACCAAGCCGAATTTGTGCAATACCTGCGGCAAGAGTTTCCATCGTGCCTACAATCTCACCATTCACATGCGCACCCATACGGGTGAGCGACCCTACAAATGCGACCAGTGTCCCAAGAGTTTCACCCAGAGTAACGATCTCAAGGCCCATATACGTCGGCATACGGGCGAGCGTTACAAGTGTCCGCATTGTGACGCCTACTTCCTGCAGTTGTATAATATGCGTAATCACTGCCTAAGTGCCCATAATAAGCACATTGAGACGAAAACGGGTCGTCTACAACGCACCGGACTCCTGGACGAGGGCAATCAATCGCATTTCACAACGGTAGTGATGCCGCCAGGGCGTTATCAAGAGAATCATCACCAACAAATAAATCAGACAAATCAATCCCAAACGCATTTGACAGCGACCTCGACTGCGGTTCTTCATTCACCGACTTCGGTTAGTGGCGGTGGTGGTGGTGTCTATAATTCCACAACCACTGCCACATCTCTGACCACCACGGGAACAACTGCTCCGGCAACTGCAGGAACTGTTGCCAATTTGGATGGAGCTAGTTTTCCCTCAACAGCGGCCCCAGCTTTTGGGGCATTTAATTTTCCACCTGTTGTAATGGCGCATCTCATGTATAACCATGGTGGAGGCGGCGGCGGAGGCAGCAGTAGCCAACATAGTCAACAGAGTAATGCCAGTGGCAGTGAACCGGCTGGTAAATAG
Protein Sequence
MATTTSGNGKANIERLCRICLRQVGEEQQFHFIYDETPMEQGANLVEILNACTSYMCERLEDAPAKMPHHICEECLKAACQAYRFKREAEKSYCSLMSLLGLEPAIKHNEVSTQTDQVALLPCEMCHDKFLNSLELRLHRNREHSGQKGSPAEEFKCKFCPQQFQKLRQLRSHLSRIHDQVDRVQCNLCDRAFSRRDHLQRHMKNMHKSHKSEEEEQPIDPDGPDELESVEVLLDDVAVGEEEGELGNDQCNTNPISSNEESDDDNDEAKKSLWLNIKPEPCLEAEPEAEQVNVKATKRRRKKAEQAEAFETTEAEVKAEPLAHVESVLHIKQESQMGPSEEENATVQIPAKSLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQAKPKVEIVREYLQKSKKPKRRRRRNRDESEPNPENRCDVCQRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHSSKEHKCELCQAAFARSEALERHKLSRHNGVGVPEGSELKHQLEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFKERQQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDEGNQSHFTTVVMPPGRYQENHHQQINQTNQSQTHLTATSTAVLHSPTSVSGGGGGVYNSTTTATSLTTTGTTAPATAGTVANLDGASFPSTAAPAFGAFNFPPVVMAHLMYNHGGGGGGGSSSQHSQQSNASGSEPAGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00618572;
90% Identity
iTF_00555247;
80% Identity
-