Basic Information

Insect: Drosophila paucipuncta
Gene Symbol: Prdm15
Assembly: GCA_035043875.1
Location: JAWNMP010000312.1:27053345-27059151[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00052 0.034 14.6 0.9 1 23 213 235 213 235 0.97

2 26 0.00038 0.025 15.0 4.1 1 23 241 263 241 263 0.98

3 26 0.016 1 9.9 0.7 2 23 296 317 295 317 0.96

4 26 0.00035 0.023 15.1 1.6 1 23 392 415 392 415 0.94

5 26 0.2 13 6.4 0.6 2 22 425 445 425 445 0.96

6 26 2.3 1.5e+02 3.1 0.7 1 20 454 473 454 475 0.91

7 26 4.7 3e+02 2.1 0.1 2 23 497 518 496 518 0.89

8 26 0.0046 0.3 11.6 0.5 1 23 593 616 593 616 0.96

9 26 0.004 0.26 11.8 0.0 1 22 625 646 625 646 0.96

10 26 0.0027 0.17 12.3 0.6 1 23 655 678 655 678 0.97

11 26 6.5e-05 0.0042 17.4 0.4 2 23 692 713 691 713 0.97

12 26 9.2e-06 0.0006 20.1 6.3 1 23 719 741 719 741 0.98

13 26 0.12 7.6 7.2 1.0 1 23 880 903 880 903 0.95

14 26 0.0049 0.32 11.5 2.2 1 22 910 931 910 931 0.96

15 26 0.4 26 5.5 0.4 1 20 940 959 940 963 0.86

16 26 5.9e-05 0.0038 17.6 1.6 1 23 987 1009 987 1009 0.97

17 26 0.00044 0.029 14.8 0.7 1 23 1016 1038 1016 1038 0.98

18 26 0.043 2.8 8.5 0.0 2 21 1065 1084 1064 1085 0.94

19 26 0.039 2.6 8.7 4.0 1 23 1130 1153 1130 1153 0.96

20 26 0.017 1.1 9.8 1.0 1 23 1190 1213 1190 1213 0.96

21 26 0.014 0.92 10.1 3.1 1 23 1240 1263 1240 1263 0.97

22 26 1.3e-05 0.00088 19.6 0.1 2 23 1284 1305 1283 1305 0.95

23 26 4.6e-05 0.003 17.9 2.9 1 23 1311 1333 1311 1333 0.99

24 26 4.2e-06 0.00027 21.2 2.3 1 23 1339 1361 1339 1361 0.97

25 26 2.9e-07 1.9e-05 24.8 2.6 1 23 1367 1389 1367 1389 0.99

26 26 0.00068 0.045 14.2 0.3 1 21 1395 1415 1395 1419 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00052	0.034	14.6	0.9	1	23	213	235	213	235	0.97
2	26	0.00038	0.025	15.0	4.1	1	23	241	263	241	263	0.98
3	26	0.016	1	9.9	0.7	2	23	296	317	295	317	0.96
4	26	0.00035	0.023	15.1	1.6	1	23	392	415	392	415	0.94
5	26	0.2	13	6.4	0.6	2	22	425	445	425	445	0.96
6	26	2.3	1.5e+02	3.1	0.7	1	20	454	473	454	475	0.91
7	26	4.7	3e+02	2.1	0.1	2	23	497	518	496	518	0.89
8	26	0.0046	0.3	11.6	0.5	1	23	593	616	593	616	0.96
9	26	0.004	0.26	11.8	0.0	1	22	625	646	625	646	0.96
10	26	0.0027	0.17	12.3	0.6	1	23	655	678	655	678	0.97
11	26	6.5e-05	0.0042	17.4	0.4	2	23	692	713	691	713	0.97
12	26	9.2e-06	0.0006	20.1	6.3	1	23	719	741	719	741	0.98
13	26	0.12	7.6	7.2	1.0	1	23	880	903	880	903	0.95
14	26	0.0049	0.32	11.5	2.2	1	22	910	931	910	931	0.96
15	26	0.4	26	5.5	0.4	1	20	940	959	940	963	0.86
16	26	5.9e-05	0.0038	17.6	1.6	1	23	987	1009	987	1009	0.97
17	26	0.00044	0.029	14.8	0.7	1	23	1016	1038	1016	1038	0.98
18	26	0.043	2.8	8.5	0.0	2	21	1065	1084	1064	1085	0.94
19	26	0.039	2.6	8.7	4.0	1	23	1130	1153	1130	1153	0.96
20	26	0.017	1.1	9.8	1.0	1	23	1190	1213	1190	1213	0.96
21	26	0.014	0.92	10.1	3.1	1	23	1240	1263	1240	1263	0.97
22	26	1.3e-05	0.00088	19.6	0.1	2	23	1284	1305	1283	1305	0.95
23	26	4.6e-05	0.003	17.9	2.9	1	23	1311	1333	1311	1333	0.99
24	26	4.2e-06	0.00027	21.2	2.3	1	23	1339	1361	1339	1361	0.97
25	26	2.9e-07	1.9e-05	24.8	2.6	1	23	1367	1389	1367	1389	0.99
26	26	0.00068	0.045	14.2	0.3	1	21	1395	1415	1395	1419	0.91

Sequence Information

Coding Sequence: atgttgcCGACGAATATTTGCCGCACGTGTGCGTTGCAAGATGACAACTTGTTGGCGTTGGCAACTCGGAGTGAGAAATACGCAAAGAAAAGTATTTGCGACATGCTGCACGAATTAACACAAAACGATCCACTGCTGGAGCATACAAATGATAAGCTACCACAGCATTTGTGCGGCCAATGCCTGAGTCAACTGGAAGCTGCCTATGCATTTGTGGTGCAGGTACGCCAGACACAGGAGCAACTGTTGCTACAGCTACGTAACAGATTGCAGACACAGTGCCTGGAGGAAACACCCATCGATATAAGCACAGAGCACATCAAAATCGAAACAGACATTGACCTAGATGCGGACATGGCTGACTTAGTCGGTGCTGAgttggaggaggagcaggagaagcagGTGGCCTTAAAATGTCAGCCGGCAACTGATAGCGATAGCAGTCAAGATAGGGTGAAGGACCATCACGTTAGGGTCAAAACCCCTCAGTTGCGGCGCAGTGCACGGCGAGCCAAACTGAGCACAGACAGCGAAAATGAGTCTTCCGAGCAGGTGCAGCCGTTGCCTGTTAAGCGTGGACGCGGTCGTCCCGCACGTCTGACCAAGAGGGAGACGACCACCAACGAGGACGGCCGGCATGTGTGCGAGGTGTGCGGCAAGACATTCTCCTGGTATCGCGACATGCAGCGCCATGCGCGCATCCACTTTGAGCAGGCGGGTTTTGTGTGCGAGCACTGCGGCAAGAAGTTCCTGCGCAAGGATAAGTACATGACACATCTGCGATCGCACAAGAAGCACGTGtccacagacagacagacactgCCACGGAGTAGCGAGTGGCGCTACGCGGAGCGTCTCTACAGCCCCGGCAAATTCATGCGTGTGGAGTGCAAACTGTGCGGCTTGAGTTGCCAGCGCATTAAGGAGTTGCGCGAGCACCTGGCGAGTCATGTTCACATTGAGACATTGTCGAATCTCAGCCTGGACAACGATGTCGTCCGAGAGCAGTTTGGCAGCCAATTGGATTTGCAGCAAATCAAGGAAAACGTGTGCACGCAAATTGCCAAAGGTCGCGAGCAACTGGAGAATTACGGCGCCGTTGTGAATGCTTACGGCTATGAGCTGTGCCTCAGCGACtcggatgaggaggaggatggGGAGCTAGCTGGAAAATATCAATGTCTGCGCTGCAATGTCAGCTTTGCACGCAAGCATCAACTCGTGCGACATACGCTCGAGGAGCACACTGACAGAAGTGAGTCTCTCTTGGAACGCTGTAATATCTGTCAAATTGGCTTTGTTTGCGCCAAGCTGCTGGAACAGCATCAGCGCACGCAGTGCCTCAATCCGCTAAAGCGTTACAGCTGCAAGAATTGTCCTGGCAAGTTTATTTGGTTGCAGAATCTGCAGCAACATGCATGCAGCAGAGCGCAACCGGATATGCAGCATCGGCATttggaacagcagcaggcaccTCATCTCCAGATCCAATGTGGCCTGTGCAAAGTCGAACCCAGCAGCATGACTGCCCTACGCTCTCATTTACTCACACATCGTGATGGACATACCGGCATTGATCCGCAGCATCAGTCTGCCTTCTTTAGCACCGTTTATTACGATGATGACGGTGCCGGCTACCTTTCGGAGCTCAAGGCACGCATCGCTGCCGATTTTGAGGCACAGCTTTATGGAAGATATTTCAATGCGTGCACGGACAGCGGACAGGAACTGGACTTCAACGACTCGGACAAGGAGTGGAGCGATGCGCCCATTCTGCACAGCTGTGCCGTGTGTGGCGAGAGTAGAATCCGCCTCGATCAGCTGCTCCAGCATCAGCAGAGCCAGCACAAAGAGCTAGTGGGCAGCCTGCCTTATGTCTGCTCCGATTGTGGGTTGGGCTATGTGGCCGAGtcgttgctgcagcagcatcgtCGTCGCATCTGCGCCAAGCTGCATGCCAAGTACGAGTGTCCCCTTTGCAGTCAGCGCTTCTATTGGTACTCCAACTACGAGCGGCACATTCAGGTGCAACATCGTACGGATAcgaagcaggagcagaagaAGAGCAAGCTGCAGTGCAGCGAGTGCGATAAGGTGTTTATCTGGCCCAAGGATTTGACGCGCCACAAGCGCATGCATCAGTCGCAGGTGCAGTTCGAATGCACCCACTGCGACCGCAAGTTTCATCGCAAGGATGGCCTTAAGTCGCACATGCGAATGCACGGCGAGCAGCCGACGTCGTCTCTCGGTGAGCAGTTGCAGCGCATGCCGATGGTATTGAGCCAGCTATGTCGCCCCAATGGCTGCAAGCAGATCAAGTGCATGATTTGCTTGTCGCAGCACACAAAGATCTCCGATTTGCGAACTCATTTGACGAGCCATCAGTTGACGCTGTGTTTGGGCGAGGAGCGAGGTATCACAAATATTTGTCGTGCTCTTTATCCGGAGCTGAGCACGCCACTGGATCAGCAGGCATTGATCAAGCGCATCCAGCGTGATCTAACCAAGGGCTTGGAGCTGGAAAGATTCGTTTCGATAACCAACGAGGCGGGCATCGAATTAAGCCTGGACAGCAGCGAAACGGACACCGATTCGGATTGTGCAGTAGAAACCGAACGGAGTAGCACGGAACCCCGTTACAGCTGTGAATTGTGCCAGGTGCAGGTGATGCGGAAGCATCAGCTATATGCCCaccagctggagcagcacacGTGGCACCAGACGACGCACGTGTGCAGCCACTGCCAGGCGAGATTCGTGAATGAGCAGCTGCTGGAGCATCACTATCGCACCCTCTGCCGCAATGCCCAGCGGCGTTTCTTGTGTCGCAAGTGTCCATTGCGCTTTCGCTGGCGCGATAATCTGAAGCTGCACAATGGTGTGGCGCATCAGGAGCGAGGGACTGTGGAACAGCACTCCAATGTGGACATTCAGTTGCGTATGCTGCCCGTGGTTAGCTACGACTGTGTCGAGTGCAAGCGTAGcttcaaaatgcaaaaggaTCTCACACGGCACACCCTGATGCATGCCCAGGAGTCGAGCATCTATCGGTGTCGCTGGTGCGCACGACGCTTCTATCGCGAGGCGAATCTGCTGCAGCACATAGAGCGACATGGTATCAGCGCCGACCAGCTGCCCTATGCGGAGGCCCTGCTCAACGCCAGCCGGCATCCGCATGGACCGAAGTGCATACAGTGTCGCGTGTGTGAATTATCCTTTGTCAGCATTGCGGCACTGCGTTCGCATCTGCAATCATCGCCAGTTGGCACTCATCATCCGATTGAGTCTATGGCCAACTATTCGATCACCAATCAGCTTGGCTACGAGCTGCACCTGGACGACTCCGAAACGGATGAGGAAGCCAAGCCGGCCGGCACTCCGGCGCATTACACGTGCGGCATGTGCCAGCTACGCTGTGTGCGCAAGTTTGAACtgcaccagcatcagcaggcCATGCATCGTCTGGAGCGCATCGCCGACGGCTGCAATCTGTGCATCTTCAAGAGCGTCTCGCCTGATCTGATTGCCTATCATCGGCGTGTGCTGTGCGAGAACACGGAGAAGCAGTTTAAGTGCTCTAAGTGCAGCTACAAGTTTATGTGGCAGGCGAATCTGGTGCAGCACATCCAACTGCAGCATCCCAGCAGCGAAGAGTcgccaacaaaaacagcaatgcCCAAGACCGTGCCCGACATTGATAACGTCGAATGCCACATCTTCCAGTGTGGTCAATGTCCCAGTAAATACAATCGCAAGGATCGCCTCACCGCCCATGTGAAAAAGTGTCACACGGCTGGCGCAACTGCGTTAACAAAATCGCCAGCGGCTACCAAGCAGCAGAAGAGTTTCCTGTGCGCCTTCTGCGGCAAGGCGGTTAGCTCATCCTCCAATTTAATCATACACATACGTCGGCACACCGGCGAGAAGCCGTTCAAGTGTGATTACTGCGACATGGCCTTTCCGCGCTCCTCCGATCTCCAGTGCCATCGACGCACCCACACCGGCGAGCGGCCCCACATCTGCACCGTCTGTAAGAAGGGATTCGCTCGCTCATacaagctgcagcagcacatgCGCATACACAACGGCGAACGGCCCTACAAGTGCACTTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTCACCCTCCACATCCGACGCCACACCGGCGAACGACCTTATCAGTGCAATACTTGCGGCGAGCGATTCATTCAGGGCACAGCGCTCAAGAACCATCGACTGCAGAATGGCCACTACGAGACGGAACTGGATCAATCGAAGGATGACTAA
Protein Sequence: MLPTNICRTCALQDDNLLALATRSEKYAKKSICDMLHELTQNDPLLEHTNDKLPQHLCGQCLSQLEAAYAFVVQVRQTQEQLLLQLRNRLQTQCLEETPIDISTEHIKIETDIDLDADMADLVGAELEEEQEKQVALKCQPATDSDSSQDRVKDHHVRVKTPQLRRSARRAKLSTDSENESSEQVQPLPVKRGRGRPARLTKRETTTNEDGRHVCEVCGKTFSWYRDMQRHARIHFEQAGFVCEHCGKKFLRKDKYMTHLRSHKKHVSTDRQTLPRSSEWRYAERLYSPGKFMRVECKLCGLSCQRIKELREHLASHVHIETLSNLSLDNDVVREQFGSQLDLQQIKENVCTQIAKGREQLENYGAVVNAYGYELCLSDSDEEEDGELAGKYQCLRCNVSFARKHQLVRHTLEEHTDRSESLLERCNICQIGFVCAKLLEQHQRTQCLNPLKRYSCKNCPGKFIWLQNLQQHACSRAQPDMQHRHLEQQQAPHLQIQCGLCKVEPSSMTALRSHLLTHRDGHTGIDPQHQSAFFSTVYYDDDGAGYLSELKARIAADFEAQLYGRYFNACTDSGQELDFNDSDKEWSDAPILHSCAVCGESRIRLDQLLQHQQSQHKELVGSLPYVCSDCGLGYVAESLLQQHRRRICAKLHAKYECPLCSQRFYWYSNYERHIQVQHRTDTKQEQKKSKLQCSECDKVFIWPKDLTRHKRMHQSQVQFECTHCDRKFHRKDGLKSHMRMHGEQPTSSLGEQLQRMPMVLSQLCRPNGCKQIKCMICLSQHTKISDLRTHLTSHQLTLCLGEERGITNICRALYPELSTPLDQQALIKRIQRDLTKGLELERFVSITNEAGIELSLDSSETDTDSDCAVETERSSTEPRYSCELCQVQVMRKHQLYAHQLEQHTWHQTTHVCSHCQARFVNEQLLEHHYRTLCRNAQRRFLCRKCPLRFRWRDNLKLHNGVAHQERGTVEQHSNVDIQLRMLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYREANLLQHIERHGISADQLPYAEALLNASRHPHGPKCIQCRVCELSFVSIAALRSHLQSSPVGTHHPIESMANYSITNQLGYELHLDDSETDEEAKPAGTPAHYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCNLCIFKSVSPDLIAYHRRVLCENTEKQFKCSKCSYKFMWQANLVQHIQLQHPSSEESPTKTAMPKTVPDIDNVECHIFQCGQCPSKYNRKDRLTAHVKKCHTAGATALTKSPAATKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNGHYETELDQSKDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00610043;
80% Identity: -