Basic Information

Gene Symbol
grau
Assembly
GCA_035047505.1
Location
JAWNPM010000080.1:1119118-1121167[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.025 1.9 9.3 1.1 6 23 286 303 286 303 0.98
2 9 5.4e-05 0.004 17.7 2.9 1 23 309 332 309 332 0.93
3 9 0.00033 0.025 15.2 2.4 1 23 340 362 340 362 0.97
4 9 0.00017 0.013 16.1 0.8 2 23 368 390 367 390 0.96
5 9 0.1 7.6 7.4 0.1 2 23 396 417 395 417 0.95
6 9 3 2.3e+02 2.7 3.9 2 23 426 447 425 447 0.90
7 9 0.0001 0.0075 16.8 0.2 2 23 455 477 454 477 0.96
8 9 4.3e-06 0.00032 21.1 1.2 1 23 483 505 483 505 0.97
9 9 0.00064 0.048 14.3 8.5 1 23 511 534 511 534 0.98

Sequence Information

Coding Sequence
ATGATTTGCCGCCTGTGCCTAAACAGCGCCAACGATACCATACAAATTTTCGAGGGCGTTGGCTCATCCCTAAACGTTGCCGCAGTGCTGgccaaatatttttggtttcagCCCAAAAACGATGATCCCATATCGACGGCGGTTTGCGTGAGCTGCTGGACACGCGTGAGTGACTTCAACGAGTTCTACTGTAGCGTGGAGAAGGCGCATCGTCTGCTCACCGAAAGGTTCTCCATAAAAAAGGATGAGCCCCAGGAAAAGCTAAGCAATGAGCAGGAGCTGCAGGACAATAAGCCAGCGGAAGAGTCCAAAGAGTTTCTTGAAAGCAGTGGACACGCCGAACTGGAAGAGGACCACGACGAGACTGCCGTCGATGCTTTGTATGCGAGCGAGAGTGAAACAGCTGCCTCCTTCAGCAACGAGCAATTTCTTTCGGATGTGCTGGGTCAGCAGGACGAGGGGGAACCCATAGCCGTTGCTGAGCCGCCGGAAGTGGTAGTCAAGCAGGAGGTGGGTGTGGTTGCTGTGCAGGAGCGCCGGGAGACGCGTGCAACACGTGCTAAGAGTAAAGCGAATCAGTTGCTAAAAAAGGAATCTCCGCCAGCTGTTAAACATGCGCCTGCCAAGCGCCGTGGTCGCTCCAAATCAGAGAAGGCTAACACCAGCGACAGTGTCGATGAGACCGCCAAGAGCAAACGTTATGTGGACTATAAAAAATCCATGTGGGAGATCGATGAAAAGATTGCCCAGCACATGCGTCTCACCTGCAGCATATGCCACGAGTGGCAGGAGACCTTTCTGTTGCTGTGCAAGCACATGCAGCAGGTGCATCACCGCAAGGGCTATGCCGTCTGCTGCAACAAGAAGTTCTACAAACGATCCTTTCTCACCGACCACATCGATCGTCATTCCAATCCCGAAAAATTTAAATGTAATCTCTGTGGGCGTACCTTTGCAGACAAGCAGTGCCTGCGCAACCATGAGCTGCTCAAGCATCAGCCCGAGGAGGAGAAGACCTTTATGTGTGAGCACTGCCCGAAGCGCTACACCAAGCAGTATTTATTGGATCAGCACAAGATCATACACAAGGAGCGCAATGTGCCCTGTGATCTCTGTGACAGGCGCTTTCCCAACTTTTCCATGCTCTGCACGCACGTGAAAATGGTGCACGGTAACTATGGCACCATGTGTGATATATGTGCGCAGGTGATACGCGGACAAGCCGCCTTCCAGCGTCATCAGCTGGAGCACGCAGGCATCACGGAGCCCAAGGTGCAGTGCGACATCTGCGGCTCGTGGCACAAGAACAAGTACAGCCTGAAGAAACATGTGAGTCGTCACAATGGCAACTCGCAGGAGAGCACCTGCAACATCTGTGGCAAGGTATCACCCAATCGCAGCGCCATGTTGAGTCACCAGCGTTATGTGCACACAGCCGATCGTGTGCACGAGTGCAGTGTGTGCAACAAGAAGTTCAAGAAGGCCATCAATCTCAAGGAGCACATGGCCATACACACGGGTGAAGTGCTCTACAAGTGTCCCCACTGTCCCAAGACCTTCAACTCCAATGCGAATCAGCATTCCCATCGCAAGAAGTGTCATCCCAAGGAGTTTGAGGAGGCGCGTAAAGCGCGACTACAGAATCGCATGGCTCCCAGTGCGACTGCCGAGAGCAAGTCCAAGGCAAGTATGATAACGATCACCACTGCAGGAGAGCAGCAGGGGGAGGTAGAGACGCATAACATACTAGTGACAACAGCGGAGcacagcgacgacgacgaggagCAGGAATTCAAGGGCGAGGACATTGAGTTCATGCTCTCGCTGAGTCCACAGCCGCAGACGGAATAA
Protein Sequence
MICRLCLNSANDTIQIFEGVGSSLNVAAVLAKYFWFQPKNDDPISTAVCVSCWTRVSDFNEFYCSVEKAHRLLTERFSIKKDEPQEKLSNEQELQDNKPAEESKEFLESSGHAELEEDHDETAVDALYASESETAASFSNEQFLSDVLGQQDEGEPIAVAEPPEVVVKQEVGVVAVQERRETRATRAKSKANQLLKKESPPAVKHAPAKRRGRSKSEKANTSDSVDETAKSKRYVDYKKSMWEIDEKIAQHMRLTCSICHEWQETFLLLCKHMQQVHHRKGYAVCCNKKFYKRSFLTDHIDRHSNPEKFKCNLCGRTFADKQCLRNHELLKHQPEEEKTFMCEHCPKRYTKQYLLDQHKIIHKERNVPCDLCDRRFPNFSMLCTHVKMVHGNYGTMCDICAQVIRGQAAFQRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVSRHNGNSQESTCNICGKVSPNRSAMLSHQRYVHTADRVHECSVCNKKFKKAINLKEHMAIHTGEVLYKCPHCPKTFNSNANQHSHRKKCHPKEFEEARKARLQNRMAPSATAESKSKASMITITTAGEQQGEVETHNILVTTAEHSDDDEEQEFKGEDIEFMLSLSPQPQTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00602095;
90% Identity
iTF_00471121;
80% Identity
-