Basic Information

Insect: Drosophila paranaensis
Gene Symbol: ZNF574
Assembly: GCA_035047545.1
Location: JAWNPL010000233.1:4600421-4602622[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.059 4 8.1 0.4 2 23 313 335 312 335 0.95

2 10 3.1 2.1e+02 2.7 0.2 6 23 345 362 345 362 0.97

3 10 3e-05 0.002 18.5 1.2 1 23 368 390 368 390 0.98

4 10 0.00014 0.0097 16.3 0.7 1 23 404 427 404 427 0.90

5 10 0.00015 0.0098 16.3 0.8 1 23 435 458 435 458 0.97

6 10 1.4e-05 0.00092 19.6 1.3 3 23 466 487 464 487 0.94

7 10 0.0023 0.16 12.5 0.1 2 23 499 521 498 521 0.97

8 10 0.00031 0.021 15.3 6.6 1 23 528 551 528 551 0.93

9 10 2.4e-06 0.00016 21.9 1.2 1 23 557 579 557 579 0.98

10 10 5.8e-05 0.0039 17.6 1.4 1 23 585 608 585 608 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.059	4	8.1	0.4	2	23	313	335	312	335	0.95
2	10	3.1	2.1e+02	2.7	0.2	6	23	345	362	345	362	0.97
3	10	3e-05	0.002	18.5	1.2	1	23	368	390	368	390	0.98
4	10	0.00014	0.0097	16.3	0.7	1	23	404	427	404	427	0.90
5	10	0.00015	0.0098	16.3	0.8	1	23	435	458	435	458	0.97
6	10	1.4e-05	0.00092	19.6	1.3	3	23	466	487	464	487	0.94
7	10	0.0023	0.16	12.5	0.1	2	23	499	521	498	521	0.97
8	10	0.00031	0.021	15.3	6.6	1	23	528	551	528	551	0.93
9	10	2.4e-06	0.00016	21.9	1.2	1	23	557	579	557	579	0.98
10	10	5.8e-05	0.0039	17.6	1.4	1	23	585	608	585	608	0.97

Sequence Information

Coding Sequence: ATGGCAGCGTGTGTGCTTTGTTTTCGCTGCTGCGACACTGCCGACTCCTATCGAATCTTCTCCGAAATTGGTTTGCGGCTTAACATTTgccaaacaataaacaaacactTTTGGTTCGAGctgagcagctcgACGGGTGAGCACGAGGAAATATGTCGCCAGTGCTGGGAGTGCGTGAGCAGCTTCAATGAGTTCTACCAGCGAGTCTACAATGTCCACCAGGAGAGACGCTGCGACGTAAAGGATGTCCACATTGAGTTCTGTGACGAATCGGTGCCGGCGAATCCCTTGGCCTTTGGCGGTGAGCTGGACGCCCTCGATGAGGATTTCTTTGGCTCCGGCGACGTCAAGGTGGAGGTGAACGAACTCGAGCCGCTGCCCAGGCTGGAACTGCTCGAAGAGCAGCTGCGGGAGGAGAAGAGCCCAGCTGCGAAGAGAGCAAGTGTGGACAATCCAGAGGGTGCTAAGCGACAGCCCTCCCTCGGCAGCGACTCGGATGGGGACATCCCTCTAGCCGATTTCCTCGAGCTAAAGCCCACCGCAGCGAAGGCAGTCCGAGCACAACCTTTGCGCCGCAGCAAGCGTCATGGGCGACGTTCGAAGACACCGCCAGCCTTGCCGTCCAACTGCATGAAAAACGAGCGCGATTCCGACGACGACATGGAGTTTCTGCCCGCGGAGGCCGTGCTGGGTACCGAGGACAGCGCCAGCTCGAGCGAGAGCAGCGACTCCGACTCGGGCAACAGTTTGCCGGACATTGAGCCGGAGGAGCGCTACGCCGAGATACCCAAGCGTGTCGTGGTCAAGCCGAAGAAGTATCGCAAACGTCCCAAGCCTCTGATTCCGCCTGTTCGCATGAGCCGCGAGGAGATCGAGAAGAGGAAGGCGCAACAGAACGAGTTCGACGAGATCATTTTCGACTTCTTCAAGAAACTGCCGTGCCACGTCTGCAACCTGCTGGTGCCCAACTTCGGGGACATGCGTCGCCACCAGCGCCTGTCCCACAACATCGAGAGCGGCTTCATCGCCTGCTGCGGCCGCAAGTTCCACATACGTCGCGGCCTGGCCGAGCATGTGCTGGTCCACAAGAATCCCGAGCACTTCATGTGCACAAAATGCGGGCGCATATTCCAGGACTCCAAGACTCTCGAGACGCACGAGCAGACGCACACCAATCCGCCGCAGACGGATGCGAAGGACAAGCGCATGTTCCAGTGCGAAAAGTGTCCCAAGAGCTTCACCACAAAGGCTGCAGTGGAGTACCACAACGCGTCCAAGCACGTGCCCAAGTCGGACTTCAAGTACTCCTGCCCAGAGTGCAAAAAGAAAGTGCCCACGGAACGGAAGCTGAAGGAGCATTTGCGGTACATGCACGATCCGGAGACTGCCATCATCTGCGACAAGTGCGGCAAGACGCTGCGCTCCCAGGCGAATCTCAAGAAACACCATGAACGGGCGCATTCCGACAAGCCACAGCCCAAGCCCGATCCCGTGCAGTGCGAGATATGCGGCACCTGGCTGCGCCAACTGTCCGGGCTCAAGCAGCACATGAGCACGGTGCACGAGCCGCCAGGTGGCGAGCATCGCTGCCACATCTGCGACAAGACGTCGACCAACTCGCGTGCACTCAAGCGCCATATATACCACAATCACCAGTGCGAGCGGAAGTTCCGATGCACCATGTGCGAGAAGGCGTTCAAGAGGCCGCAGGATTTGAGAGAGCACACGTCCACGCACACCGGCGAGGTGCTCTACACCTGTCCGAACTGCCCGCAGACGTTCTTCTCGAACGCCAACATGTACAAGCATCGCCAGCGGCTGCATCGCGCCGAGTGGGAGGCGGACCGCAAGAAGCCGCTGCCGCCGAACATCATGCAGCAGGCAATGGGCGCCACGACAGCCACGAAGAAGCGGCTGACCGTCGAGTCCACGACTGCTGCGCCCAACCCCAAGCAGGACCCAAAAAGCAACTGCAGCGGGAGCAATAGCACTTAA
Protein Sequence: MAACVLCFRCCDTADSYRIFSEIGLRLNICQTINKHFWFELSSSTGEHEEICRQCWECVSSFNEFYQRVYNVHQERRCDVKDVHIEFCDESVPANPLAFGGELDALDEDFFGSGDVKVEVNELEPLPRLELLEEQLREEKSPAAKRASVDNPEGAKRQPSLGSDSDGDIPLADFLELKPTAAKAVRAQPLRRSKRHGRRSKTPPALPSNCMKNERDSDDDMEFLPAEAVLGTEDSASSSESSDSDSGNSLPDIEPEERYAEIPKRVVVKPKKYRKRPKPLIPPVRMSREEIEKRKAQQNEFDEIIFDFFKKLPCHVCNLLVPNFGDMRRHQRLSHNIESGFIACCGRKFHIRRGLAEHVLVHKNPEHFMCTKCGRIFQDSKTLETHEQTHTNPPQTDAKDKRMFQCEKCPKSFTTKAAVEYHNASKHVPKSDFKYSCPECKKKVPTERKLKEHLRYMHDPETAIICDKCGKTLRSQANLKKHHERAHSDKPQPKPDPVQCEICGTWLRQLSGLKQHMSTVHEPPGGEHRCHICDKTSTNSRALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQAMGATTATKKRLTVESTTAAPNPKQDPKSNCSGSNST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508523;
90% Identity: iTF_00573516;
80% Identity: -