Dpar010624.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila paranaensis
Gene Symbol
Znf296
Assembly
GCA_035047545.1
Location
JAWNPL010000168.1:2083175-2084568[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 7.8e-05 0.0053 17.2 1.1 3 23 13 33 12 33 0.96
2 10 0.0012 0.084 13.4 4.1 1 23 39 62 39 62 0.93
3 10 3e-07 2e-05 24.8 1.7 1 23 148 170 148 170 0.99
4 10 3.3e-05 0.0022 18.3 2.1 1 23 176 199 176 199 0.96
5 10 0.0073 0.49 11.0 1.8 1 23 205 228 205 228 0.92
6 10 0.0079 0.54 10.9 6.8 1 23 273 295 273 295 0.98
7 10 3.3e-06 0.00022 21.5 3.4 1 23 307 329 307 329 0.97
8 10 9.2e-05 0.0062 16.9 2.6 3 23 337 357 335 357 0.96
9 10 1.9e-05 0.0013 19.1 0.4 3 23 366 386 364 386 0.96
10 10 1.5e-05 0.001 19.4 0.7 1 22 392 413 392 416 0.92

Sequence Information

Coding Sequence
atgaaaaatgttgcaaagtataaaagtttaaataactGTGAGACGTGCAGTAAGTGCTTTGCCAAGCCTGCTTTACTGCGTCGTCATCTGGTGGTGCACAGCATGGAAAAGACTTTTCCAtgcggcagctgctgcagtcgttTCTCTCAAAAAAGTTCACTGCAACGCCACATGCGCAGCAAACACGATGTGGCCAAGGAGTCCGCCGACGACTCAGACGTAGCGCAGCATGCGCTGGCTGCCCTCAAGCTGCTGCAAGGCGGCCATGCGACTGCAGATAACGCAGTTGTGAGCCAAGAGGAAGCAGCAGCTTCACATGGCACACTGGAGGAGACACCAGCTTGTGATATAGTAGAACTAAGAGACAAACTCAATCCGGCTGGTGAAGTCCACATGCTCATCACGCAGCGCATACTGCGACAGCGACCCATTAGGTGCTACTATGTGTGTGAATACTGTTCTAAAGAATTCAGCAAGAGCTACGATTTGATAAGGCATCGTCGCTCGCACACCAAAGAGACGCCCTATCCGTGCAATCAGTGCTTCAAGCGGTTTGCCACGCAAAGCAAGCTAAATGAGCATTCCAAACGGATGCATATTGCTCTCAGAAAACATGTCTGCAGCGAGTGCATCGCCAGCTTTAGCTCTAAGAATCAGCTGCACAAGCACTTGGCTGGGCAACATCCCGATACAGTTTATAGCTCCAGGCACTGCAGTCGCACCTTTCAAACGAAGTCAGCCTGCGACGCACATGGGAAACTGGAAACAGATACACTCATGAAACTATTGCCGCAGCCTGTGCTATCGCAGCGCAGCTTCAAGTGCCTCTACTGTGAAAGGAAATTCAATCGAAAATTCAATTGCCGCACGCACATGTTGCTCCACTTGCGGCGTTTGATGGATGCAAAGCAGCTAAAGCATAGTTGCCTGCAGTGCGGCAAGCACTTCAAGCGGCCCAACGACTTGGCTCGGCATTTGCTAACGCACTCCAAGCTGAAGCTACACCTATGCCAGGTATGTCAAAGACGCTTTACTCTAAAGTCCACATTGGCCAGGCATTTGGAGACGCATCAGCCACAGCGAAGTAGCGTTAACTGTCAGGTTTGCGGCAGGAGGTACGCTTCCAAGACGTCGCTTCAGCTGCATTTGCGCCTGCACACCGGCGAACGGCCCTTTAAATGTGAAATATGCGGAGAAACGTTTCGTACGTCGGGACACAGACTGGAGCACATACGAGCCGAACGGCACAAGAATGCGACTCATtgtttgattaaattttaa
Protein Sequence
MKNVAKYKSLNNCETCSKCFAKPALLRRHLVVHSMEKTFPCGSCCSRFSQKSSLQRHMRSKHDVAKESADDSDVAQHALAALKLLQGGHATADNAVVSQEEAAASHGTLEETPACDIVELRDKLNPAGEVHMLITQRILRQRPIRCYYVCEYCSKEFSKSYDLIRHRRSHTKETPYPCNQCFKRFATQSKLNEHSKRMHIALRKHVCSECIASFSSKNQLHKHLAGQHPDTVYSSRHCSRTFQTKSACDAHGKLETDTLMKLLPQPVLSQRSFKCLYCERKFNRKFNCRTHMLLHLRRLMDAKQLKHSCLQCGKHFKRPNDLARHLLTHSKLKLHLCQVCQRRFTLKSTLARHLETHQPQRSSVNCQVCGRRYASKTSLQLHLRLHTGERPFKCEICGETFRTSGHRLEHIRAERHKNATHCLIKF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00516414;
90% Identity
iTF_00586823;
80% Identity
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