Dpar013003.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila paranaensis
Gene Symbol
zfh1
Assembly
GCA_035047545.1
Location
JAWNPL010000173.1:20166759-20168668[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.12 8 7.2 0.3 1 21 283 303 283 304 0.95
2 10 1.3e-06 8.6e-05 22.8 1.0 1 23 312 334 312 334 0.99
3 10 0.0067 0.45 11.1 0.6 1 23 337 360 337 360 0.93
4 10 1.2e-06 8.4e-05 22.8 0.8 2 23 367 388 366 388 0.98
5 10 7.8e-08 5.3e-06 26.6 0.7 1 23 394 416 394 416 0.98
6 10 3.3e-06 0.00023 21.5 2.6 1 23 422 444 422 444 0.99
7 10 0.00039 0.027 15.0 4.6 1 23 450 472 450 472 0.99
8 10 0.00098 0.066 13.7 0.3 1 23 478 500 478 500 0.98
9 10 7.4e-05 0.005 17.2 3.6 1 23 506 528 506 528 0.99
10 10 0.00064 0.043 14.3 0.2 1 23 534 556 534 556 0.97

Sequence Information

Coding Sequence
ATGGATGTGGAGAAGATTTGTCGCACTTGCTTGAGTCTCACGGGTCCATTTTTGTCTATCTACGATGGTGGCCCCGGCAGCTGCTTGGTTGATATGCTGCGCGAATTCACGCGCACCAAGCCGCGCCGCGAAGATAATTTGCCAGCCAGGGTTTGCCTTAGCTGCATCAGCGAAATAAACCATTGTTACTCGTTTAAACTGAAATGTGAGAACTCAAATCGTACGCTGCGACAGCTGCTGCCCAACGCGCTGCCCGAGGAGTCCGATCAGCCGCTCCCACCTGCAGCCAAAACAACAGTCACGACATCCGACAGCTCATCTCAAACGTCTGTGGTTGCAACAGTCAGCAGTGAGGTGCAAACGGATGAGGTAGAAAAAACAGATGCGGAACAAAACACATCTATTGAAGAGCAACCGAAGCAGCACACAATGCCTGTAATGGAGGAGGCCGAGGAGCAGCCGGGCCAGGAGGAGGAAGAATATGATTACGAATTTACTGAGGAGCAGGAAACAGATGAGACGCCGTCCAAGACCAGTGCCGAGAATATAATACTGCATGTGGAAAAAGACAACATCAAGTTCGAAACGGAAATGGTGTACAATAAGAATACTGGCGAGCTGCTTGAACAGCCTGCGGAAACTGTTGCCAAGCAGAAGGAGTACAAATATCGGCTTGTCAGCAATGGTAATGGGGACACATACATCTCTCGGGAGCCGCCGTCGAAAGAGCAGCAATCGAGTCAGCAGGAGTCGCAGTCAACGTCCAAGCGCAATCATCTGGGTGAGCCGGATGCAAAGAAATCAAAGCCCACACCCGCCGCTGAGGGAGATGAACTGAAGGCTAAGTTCCACTGTGATCGCTGCAATGCGGGTTTTGCATTGGAGAAATCGCTGATTATTCATCGGAGGCAGAACAGCTGCACCCACCGCAACTTCAAGTGCAATGAATGCGAGCGAGTGTTCGTCTCGCTCGATCACCTGACCGAGCATCAGGCCACACATGGAGCGTTCATATGCCAGGAGTGCGGCCTTCGGTGTGAGTCCATGGAGCAGTTGGGCAGGCACATGGTGCAGACGCACAAGCGGAATCTACGCAATCAATGCAACGTGTGCCAGAAAGTTTTCACTATGCTGTCTACATTGCGGGATCACATGCGCATTCACACCGGTGAGAAACCGTTTGTGTGCAATATCTGTGGTAAAGGCTTCACACAGAATGCGAATCTGCGCCAGCACAAGATGCGACACTCGGACATAAAGCGATTCAAGTGTACACAGTGCGATCATTCGTTTGTGACCAAAGCGGAGCTAACGTCTCATGGGCGTACCCACACGGGCGTCAAGCCGTATCAATGCGAGGTCTGCTCCTCCAGATTTACGACGAGCTGTTCCCTGGCCAAgcacaagcgcaagcacacagGCGAAAGACCCTACGCCTGTGATCTGTGTCCCATGCGCTTTACTGCACTGAACGTTTTAAAGAACCATCGGCGTACGCACACAGGCGAACGTCCCTACGTCTGTCCCTTCTGTTCGAAGAGCTTTACGCAACGTGGCGACTGCCAGATGCATCAGCGAACGCATCAAGGCGACAAAATCTACATTTGCCCGGTGTGTAGCGAGGAGTTCAAAACGATGAACGATATGCGCTCTCATCTGACAGTCCACGAGCAGGATGACAAACGTCTGGTCCACTTCGCCCTGCTGAGCAACAAGGAAAACGGGAACGCGGCGACGCTGGAAGAGGCTGACGAGGATGAGTCGGATGCAACCGACTTACTGTAG
Protein Sequence
MDVEKICRTCLSLTGPFLSIYDGGPGSCLVDMLREFTRTKPRREDNLPARVCLSCISEINHCYSFKLKCENSNRTLRQLLPNALPEESDQPLPPAAKTTVTTSDSSSQTSVVATVSSEVQTDEVEKTDAEQNTSIEEQPKQHTMPVMEEAEEQPGQEEEEYDYEFTEEQETDETPSKTSAENIILHVEKDNIKFETEMVYNKNTGELLEQPAETVAKQKEYKYRLVSNGNGDTYISREPPSKEQQSSQQESQSTSKRNHLGEPDAKKSKPTPAAEGDELKAKFHCDRCNAGFALEKSLIIHRRQNSCTHRNFKCNECERVFVSLDHLTEHQATHGAFICQECGLRCESMEQLGRHMVQTHKRNLRNQCNVCQKVFTMLSTLRDHMRIHTGEKPFVCNICGKGFTQNANLRQHKMRHSDIKRFKCTQCDHSFVTKAELTSHGRTHTGVKPYQCEVCSSRFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCSEEFKTMNDMRSHLTVHEQDDKRLVHFALLSNKENGNAATLEEADEDESDATDLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00551023;
90% Identity
iTF_00544636;
80% Identity
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