Dpar000913.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila paranaensis
Gene Symbol
hang
Assembly
GCA_035047545.1
Location
JAWNPL010000022.1:2867199-2881632[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.38 25 5.6 1.0 3 23 527 548 526 548 0.93
2 18 1.1 73 4.1 3.2 3 22 655 674 653 674 0.89
3 18 0.00081 0.055 14.0 3.3 1 22 776 797 776 799 0.90
4 18 0.093 6.3 7.5 0.1 2 21 811 830 810 831 0.93
5 18 0.00094 0.063 13.8 0.2 2 23 959 981 958 981 0.95
6 18 0.0027 0.18 12.3 0.1 1 23 989 1012 989 1012 0.96
7 18 0.00021 0.014 15.8 0.2 2 23 1098 1119 1097 1119 0.97
8 18 0.00039 0.026 15.0 2.9 2 23 1207 1229 1206 1229 0.97
9 18 0.03 2.1 9.0 0.2 2 23 1238 1260 1237 1260 0.95
10 18 0.0016 0.11 13.0 0.1 1 23 1273 1296 1273 1296 0.97
11 18 0.00017 0.011 16.1 1.1 1 23 1344 1366 1344 1366 0.99
12 18 0.0026 0.18 12.4 0.9 1 23 1374 1397 1374 1397 0.96
13 18 0.092 6.2 7.5 0.4 2 19 1405 1422 1405 1423 0.94
14 18 3.6e-05 0.0024 18.2 0.4 3 23 1533 1553 1532 1553 0.98
15 18 0.0068 0.46 11.1 0.1 1 23 1588 1610 1588 1610 0.97
16 18 0.0008 0.054 14.0 0.6 2 23 1699 1721 1698 1721 0.93
17 18 0.0087 0.59 10.7 0.3 3 23 1777 1797 1777 1797 0.98
18 18 5.1e-05 0.0035 17.7 2.3 1 23 2236 2258 2236 2258 0.99

Sequence Information

Coding Sequence
atgtGCGACGCTGtcgcaacaccaacaacagttATGCCAGCAGGAGGATCAGGATCTGGAGTGCAGTCTGCTGGCGACAGCACATTGACGGCCATGGAGGAGCGCCAGCGACAAAGTTGCTGCCGTCTGTGCATTGCGCCCGCCAGCGAATGCATTTCGATCATTAACAGTTATGCGGCCGATAAGGAACCGTTGGCCACTAAAATACACAACTGCGTAAATATCAAGaTCACGCCACTGGATCGTCTATCGCTGCATATTTGCCATGCCTGCATCAGCTATTTGAACTCCTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGTCGAAGCAACGGCAATGGCTGGACAGCGACAAGAGCAAGCAGCAGACGCTTCTCGGATACTTGGATTTGAACAAAACGGAGAATGGCAGCTCCAttgaacaacagcagcaacatcagcagcaacagcaacagcacgaATCGAATATCGATTCGGCGGCGATTGCAGCTGAGAAGGCGTCCGCCAACATTTTGGATGGCATTCCTTCGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCaaagcaacagctacaacagcaacatcaacagctacaacagcaacagcagcagcagcaacaacaacaacaaccgcagcagcagcatgctGCAGCCAGAGCGACGAGCGCAGCGGCAGAATCACAGCAAACGCTGCAGACCCTTTTATTGCAGGTGCCCtcaacagccgcagccgcagcattgGCAACAACGTCAacgcagcatcagcaacagcgcaaatatcagcagcagcaacaacgtgtcaagcaacaacagcattatcaacaccaacaacaacaacaacaacatcaacagcagcagcgcttgaGTCGCATACGTCAGCcgcgacgccagcagcaggcgacaATGTCCGGGCAGCGCTTGGTCAAATTTAAGCCGAAATTGTTTTTGCCACTGGATATTGcggtgccgccgctgccaccgCTGCCACCGCTGCCACCGCTGTTGCCGGCACAGCCGTCAGacactgttgctgttggtgctaaGTTGGCGCAGTTGCCtgtgccgttgccgttgccgttgccactTGATTttagccagagtcagagtcagcaGAAACATGGCAGcgtgttgccgttgccgctcccattgccgccgccgccgccgtcgctgccagctgcaacAATAACCAGCaacgccgctgccgctgcctcgagCTCTGCCGCTGGCGcgagctctgcctctgcctctgcctctgcctctgtcgcagccgcagccgcagtcacGACTCCACTGCTCATGCCGCCTCTGCCCGCCGTGCCGATCAAGGATGAGCCCATTGATGATACGGACGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGACATGATGGATCCAACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTGCCGCTAATGACCTCCGACTATGATTACACGGCGCAACACGGCGTGACGGCGGTTGCGGCGGCAGCATCGCTGCCCGCCAGCGCGGTTGCGAACGTGGCCGCCGCCGGCGACTCTAAGGTGGCCAGCTGTCGCGCCTGCAGTCTGCAGTTCTCGACGCGCGCGAACGCCCGACGCCACGAACGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGACTCGCCAAACAATACGCCGATCACAAAGCCGACGCCAGCACTGGCCGCCGCACTGGAAATTCAGCGTgccgcagcggcggcagccgcCACAGCGGAGGCAACCAAAGCCGCCGCCGGCGGTAACATATCAGCGCAAAAGTATCGCCAGGTGATAATGAATACGTTCATCAAGTGCGAAAACGGGGGCTTCGACTACGACAACCCGGAACAataccagcagctgctcacgCGCGACAAGGTGGAGTTCATCCAGGAGAACAACGAGTTCCTCGAGCAATACCAGACAATGACGTGTCGCTGCTGCAACAAATACTTCAACACCTACAAGAACTTCATGGCCCACGTCCGCAAGAAGTATCCGCTGCTGCCGCGCAACCTCTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTCTTCATATCGCACCTTAAGAAACGCAACTGTATCAACCTCTATCGCGTGCTGAACGCCCTGCGCCTCAAGCTGCCCAACTTCTCGCACGCCAACGCAGCCGGCGTCGCTGTCTCGTCGGACCTGAGCCAGGCCGTCTCCCTGGCAGCAGCGGGCTCGGGATCAGCTGGCATGAAGCACGATGCGTCCGCGGAGCGCCCCGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAACAAGCTGTACGAGTGCAAGCTCTGCCCGAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCATGTCTACGACAAGCATGCGGATGTGCAGCGCAAGGACAACAACTCGATACAGTGCAGCTTCTGTGGCTTGGACTTTGCGGATCCCGTCGACCGACGTCGGCACTACAACAATATGGAGTGCATTGTGCGGCTGCGCTGCATGACCTGTGATGCCAAGCTGGAGACGCATCAGCGCTTCCTCGACCATGTCTACCAGGATCACCTGGGCGGCGTGAGCAGTGATAATGCCTCGACGGCCAACAGCGGCATGGATCATTCCCCCGGCAAGCGCAGCCTGCTCGGCGCCCTGGGCATCGGTGTCAGTCAGTCGTCCAACGATGAGTCCCGCAGCAgcacccacaacaacaataatgctGTGGAATTGCCCTTTACCTCAACGCCCAAGATGGCGGGCGCAGCAGCTGGGGGAGCGGCGACCAgtgccggcggcggcggcggcggctcctCCAGTCGCGATGCACCCAAATCGCAGTATTTCTCCCGCATGCCTCAGGTCTGCCCCATCTGCGGGCAGCagtacaacaactacaacaacgtGCTGCGCCACATGGAGTCGAAGCATCCCAACAAGCTGCCCGAGACGTACAAGTGCGTGCGTTGCGGCCTGGGCTATCCGCGCATCTCCTACCTGCGCGAGCACATGATCAACGTCCACGGCGTGGACAAGAATCGTCACTCGGGCGGCTTCGAGTACATCGTGAATGCGGACGCCGTGAAGCTGGCGGATGGCAGCACGCCGAATGTCTATACGGGCCGCTACGACTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgATGAAGATGATGAGGAAACTGGAAGCGTCGCGAAGAAGATGCGATtggacgacagcagcaacaacagcagcatcaacatgGGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAATAACATTGGCTTGTCGAACCACATGCGCTCCCATTACACCGCCTCGACGGCAACGAATGCCGCGCTGGCGGCTGCCAATCGCATGACGCCCAAGTCCTTGACAATTACTGCAACGCCGCCATTGGAGGCGACTGCGGCTACTTCGACGGCGGCGCCCGtcacagcggcagcagccggagccacgcccacagccgcTGGCGGCTTGCCGCCCGCGATGGTGCACCAGACGCCACAGGAGCAGGCCGTGTTCCGTCGCAGCCTGGATCAGGCGGCCGATCGCCGTTTCCGGCGCATGCGCTGCCGCATCTGCCAGCGTCGGTTCAGCTCGAAGAAGTCGTATCGCTACCACATGCTCACCGACCACCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTCTGCAATGCGGAGTTCGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCGATCAAGGACGAAATGATCATCAAACAGTTCGAGTGCGATATTTGCTCAATTGTCTACAGctcggagctggagctgcagcagcacaagcGCAGCGTCCACAAAACCCTCGATGGCGGCTCGAAATCAGCAACCAAATCATCTACCGctacctcagcctcagcctcagcctcagcctcagctgaCCAGCAGCTGACCACCGACGCAGCGGGCGCACCCGTGGCCGTCATGCCGCTCTACTGGTACCAGTGCAAGTACTGCCCCTCCAACTTCAATACCAACAAGAAGTTGGCCATCCATATCAACTCGCACGACGAGTTCGACTCGAACGACTATTCGTGCAAGGACTGCGGCAATGTCTACAGCGGACGCAAGAGCCTCTGGGTACATCGCTATAAGAAGCATCCGCAGGTGCCGGATCCAGCCGAGTGCACGCTCTGCCGCAAGATGTTCTTTGATCGCCAGATGCTGGAGAATCACACGCCCACCTGCAATCGGAAACCCATTACGGCCACCGGCGCCCATCAGCAGgatcagcaccagcagcaccagcagcagcaacaacagcagcaccaacaacaacaacagcagcagcagcaacaacagcaacaacatcgcgCCGTATTCAAGCATAAGAcgggcgacgacgacgacgaggaggacgaTGAGCGGCTAATGATGCTGGACGATGGTGCcgctggcagcgacagcaacggcGGCACTGCGGCGCCCAGTGCGCCGTCGGCCAGCAGCAATCCGAATACGACGATAAGCGCTAGCACACTGAAGATACGGATCCCGGAGGTGGCGTGCACCATTTGCGGGGCCCGCTTCACCGACCAGGAGATGTTCACCAAGCACATACAGAAGCACGAGCAGGATCTATATGTGGACAACCCGTTGGCGGCCATGTTCGACGACGGCCCCGCCGATGCGGGCCAGTTTCAGGTGGAGCGCCAGAACGAGAATGGGGAATACGCGTGCGACTTGTGCGCAAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCTCATCATCGACGGCGAAGCGACAACGctgaacaacagcagcaccaacaacaacaacaacaacaacaattcgctGAGCTCCTCATCGATGCTGCGCGAGCTGCATGCGGTGGGCCTGATgcccaaccagcagcagcaccagaagcagctgcagctccagcaacagcaactgcagcaacaacagcagcggagCAACACCTCGAGCGGGTCGAGCAAGTCGCTGAAGCGCAAACGCGAACTGAAATGTGAATATTGCGCCTCCACGttcatcagcaacaacaacctgcGCCGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCGGAGCCGCCGGTCATCGAGGTGGACAAGCCGCTGACGTGTCGTCGCTGCGGCGATAAGCGGTTCGAGACGAAAGAACTGTGGATCGAACATAAGCTAGCGGACGCCAAGGTGGTGCGTCCCTTCTGTCCATTCCAGTGGGGCTGTGATCTGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAAGATGTGATAGTGCCGGTGTCGGCGGTGGCCAAGGCATCTCCAGCTGCCGGGCTGAACAACAAGAATGCAACGtccaaaacaacagcagcagcagcaacaacaacaacaacaactggaataataacaacaactgggGCCAAAGGCGCCTTAATTGGagcggcgacggcagcagtGAGCGGCGGCAAAGTGAATAAGAGTAAGCAGCTGGAGGTGGcagcgaaacaacaacaacaacaacagcagcagcagcaggatgaTGAGGAGGACAACAGTGATATGGATgaggacgatgatgatgacacTGATAGCGGCGATGGGGATAGCACGAGTGGTgatgaggacgacgacgacgacgacgatgatgatgacgatgaggGCGACGTggacgacgatgacgaagaGGACGATGAGGAAGTTGTTGCACAACAAATGctgcaacagaaacaacaacaacaacagcagcagcagcaacagcaacagcaacagcccctcaacagcaacagcaatgatGACGACGATCTCATTGAGGAAGTCATCGAGGATGATGGCATTGTCGAAGAGctggacgacgacgatgacgaggaTGAGGACGATGATGAGGGCAACAGCACGGATGAGCACcatcagcagctggcagccaacAACACTAAGCAGCAGGGCACCGGGCGCCTCAACTTCGACTACTCGCGGGCCAAACTGAACGGAACTGGCAACAGCAAGCAGACGCTGGCCaagccgaagcagcagcagcagcagcagctggtcaTGCACAGCTCGGAGGAAGACGATGACGGTGCCGaagaggaggacgaggaggatgATGATGTGGCTGAAGCGATGACCATTGATGATATTATTGAGGAGGATGATGGAgaggatgaggatgacgaTATGGTTGCGGTCGATGGTGGTATTGttgaggacgacgacgacgacgatgtgGAAGAGGATAtggatgacgatgatgatgaagatgatgacgatgaggacgacgacgacgacgacgacgatatTGGCAACAACAGTCGTCGTCGCGACGGCGCTGTGATGGTCAGCGGCATCAGCATTGGCGACGGAGCGCCCGATGCTGATGGCGATGCAGATGGTGATGCTGATGCGGATGGCgatggtgatggtgatggtgatggtgaCGGCGATGCTGATGGTGATGTGGACCCTGAGGCTACATCATCATCGGAGAGcgagtcaacaacaacaacatcgcaTTCAATTGGTGAGCGGCGTAAAAAATCAGTTGTTAAGTCGGCGGCACATGGCGCTGCCGCTGATCACTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTcccaggagcagctgcagtcaCATATTAAAAGTCATTTCCTGAACGGGCCGTcggcgggcggcggcggcggcagcagcagtaatagtagcagcagcagtggtaACAGCAGAAGGAttgctgcgagcagcagcagcagcagcagcagcagcggcagcaacaggaccaacaacaataataacaacaacaacaacaataataataataataataataataataataataataataatagcagcAAAAGTAAAACCAAAAAGTCCAACTTGGATGCAACGAAAGGTGAcagtgctgcagctgctgctgaagcagcaacaacaacaacgacaacagcggcggcagcaacagcaacagttgctgctgaagctgctgccgAGGCAGCAAACAGCTTGAACTGA
Protein Sequence
MCDAVATPTTVMPAGGSGSGVQSAGDSTLTAMEERQRQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLDSDKSKQQTLLGYLDLNKTENGSSIEQQQQHQQQQQQHESNIDSAAIAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQHQQLQQQQQQQQQQQQPQQQHAAARATSAAAESQQTLQTLLLQVPSTAAAAALATTSTQHQQQRKYQQQQQRVKQQQHYQHQQQQQQHQQQQRLSRIRQPRRQQQATMSGQRLVKFKPKLFLPLDIAVPPLPPLPPLPPLLPAQPSDTVAVGAKLAQLPVPLPLPLPLDFSQSQSQQKHGSVLPLPLPLPPPPPSLPAATITSNAAAAASSSAAGASSASASASASVAAAAAVTTPLLMPPLPAVPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVIMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKLPNFSHANAAGVAVSSDLSQAVSLAAAGSGSAGMKHDASAERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMECIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSTHNNNNAVELPFTSTPKMAGAAAGGAATSAGGGGGGSSSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDEDDEETGSVAKKMRLDDSSNNSSINMGIANQQKECLICNAVFSNNIGLSNHMRSHYTASTATNAALAAANRMTPKSLTITATPPLEATAATSTAAPVTAAAAGATPTAAGGLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDICSIVYSSELELQQHKRSVHKTLDGGSKSATKSSTATSASASASASADQQLTTDAAGAPVAVMPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQHQQHQQQQQQQHQQQQQQQQQQQQQHRAVFKHKTGDDDDEEDDERLMMLDDGAAGSDSNGGTAAPSAPSASSNPNTTISASTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLIIDGEATTLNNSSTNNNNNNNNSLSSSSMLRELHAVGLMPNQQQHQKQLQLQQQQLQQQQQRSNTSSGSSKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDKPLTCRRCGDKRFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVSAVAKASPAAGLNNKNATSKTTAAAATTTTTTGIITTTGAKGALIGAATAAVSGGKVNKSKQLEVAAKQQQQQQQQQQDDEEDNSDMDEDDDDDTDSGDGDSTSGDEDDDDDDDDDDDEGDVDDDDEEDDEEVVAQQMLQQKQQQQQQQQQQQQQQPLNSNSNDDDDLIEEVIEDDGIVEELDDDDDEDEDDDEGNSTDEHHQQLAANNTKQQGTGRLNFDYSRAKLNGTGNSKQTLAKPKQQQQQQLVMHSSEEDDDGAEEEDEEDDDVAEAMTIDDIIEEDDGEDEDDDMVAVDGGIVEDDDDDDVEEDMDDDDDEDDDDEDDDDDDDDIGNNSRRRDGAVMVSGISIGDGAPDADGDADGDADADGDGDGDGDGDGDADGDVDPEATSSSESESTTTTSHSIGERRKKSVVKSAAHGAAADHSNSSYTCDLCQLCFDSQEQLQSHIKSHFLNGPSAGGGGGSSSNSSSSSGNSRRIAASSSSSSSSSGSNRTNNNNNNNNNNNNNNNNNNNNNNNSSKSKTKKSNLDATKGDSAAAAAEAATTTTTTAAAATATVAAEAAAEAANSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00573462;
90% Identity
-
80% Identity
-