Basic Information

Insect: Drosophila paramelanica
Gene Symbol: ci
Assembly: GCA_035043915.1
Location: JAWNMO010000179.1:501340-511058[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.042 2.6 8.6 0.8 3 23 471 494 469 494 0.93

2 5 0.1 6.3 7.4 0.2 1 23 502 529 502 529 0.84

3 5 0.00019 0.012 16.0 2.9 1 23 535 559 535 559 0.98

4 5 0.00033 0.021 15.2 0.4 1 23 565 590 565 590 0.97

5 5 7.8e-06 0.00048 20.3 0.3 1 23 596 621 596 621 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.042	2.6	8.6	0.8	3	23	471	494	469	494	0.93
2	5	0.1	6.3	7.4	0.2	1	23	502	529	502	529	0.84
3	5	0.00019	0.012	16.0	2.9	1	23	535	559	535	559	0.98
4	5	0.00033	0.021	15.2	0.4	1	23	565	590	565	590	0.97
5	5	7.8e-06	0.00048	20.3	0.3	1	23	596	621	596	621	0.97

Sequence Information

Coding Sequence: ATGGATGCGTACACACTACCAACATATTTTCCCTTGGCATACACCGAACTGCAGTTTTTGGCGTCAAGGAGggcagctgccgcagctgcggctgcttctGTGCTGCCGAGCTCACCATCATCTGGCAACCAGGTGCACATAACGGATGTGAGCAGCTCGGTGCCAGTTGCTGCGTCTCCGTTGCCACCAGCGGTTGCGGACTCAACGCTGGCCCCGACCCTCCCACCAAGCCCAAACGGCGGCGCCGGAAGCCATACGTTGCTGGGCAGCGCTGGtcaccatcaccatcatcatcatcatgtgCATGGCCACAATGTGGGCGTGGGCATGGCTGGGCAATCGCAGCAGCATGACTTTCATCCGGCCTATAGAATCCCCAGCTACATGGAACAGTTCTATTCCTTGCAAAGAACCAGCCCCACCGCCTCCTATCACGatccGTACGCGAACTGCCCGCCAGCATTCCATCTGGCCGGCCTGGGTCTGGGATCCGGCGAGTATTTAAGCGCGCGTGGAATGGGCTCGCTAAGCGAGCTGCACCATGCCGctgtggcggcagcggcggccgcTGCAGCTGGATCTCTGGCGAGCACCGATTTTCATTTTAGTCTGGACGGCAACGGGAGGCTGGGCAGTCCCCGTccgggcggcggcggcggcggcagcatgcGGGCAAGCGTCAGCCGGAAACGAGCACTGTCTTCATCGCCATACTCGGATTCATTTGACATCAACTCAATGATACGCTTCTCCCCCAACTCCCTGGCCACCATCATGAATGGCTCCCGTGCGAGCAGCGCGGCGAGCGGCTCCTATGGCCATCTATCTGCCAGTGCCATCAGTCCCATCGCACACGCCCACACCACAATGGCGCCTCAtctccagcagctgcaggctcACCTGCTACGCGCCAGCGCCGGACTCCTGCATCCAATAACGCCACAGcaagcggcggcggcggcggctgccagCTACTCGATGAGTCATGTGGCCAGCGCCGCCGCTCTCGGCCTGACCGACGTCTCCGTCAAATCCAAAGAGTTGACGTTGGCCACCGCCAGTCAAGCCTCGACGCCAACTTCCACATTAATCAGCACAGCTGCAGATGAATCCGCGATCAAACCACTCGGCTCCAATAAGAACTACGATGATGGCAACATTGAGCGGCCTCGGGCGACCAAAAGCAAGTCCCTGGAACTACCCTCATCCACGTCGGAGAGCGTTGCCCAAGTCGAGGCCGACAGTGCCTCAGCTAATCTCCTGGAGCGGCGACAACGGAACAAGTCTTTGGCCGCACATCGGGTGGTCAGTCATGACGAAGGCAACGAGCATGCGTTCAACGAATATGATTGTGCTACGGCGGACACAACGGACATTAAGGACGAGCCGGGTGATTTCATAGAGACCAATTGCCACTGGCGCAACTGCAGCGTCGAATTCATGACCCAGGACGAGCTAGTAAAGCACATCAACAACGACCACATCCAGAGTAACAAGAAGGCCTTCGTCTGCCGCTGGGAAGACTGCTCCCGTGGCGAAAAGCCATTCAAGGCGCAGTACATGCTGGTGGTCCACATGCGCCGCCATACCGGAGAAAAGCCCCACAAATGCACTtttgaaGGATGCTATAAGGCGTATTCGCGCttggaaaacttaaaaacacatttgcgCTCCCACACGGGTGAGAAACCGTACACCTGCGAGTATCCCGGCTGCAGCAAGGCCTTCAGCAATGCAAGCGATCGTGCGAAACACCAGAACCGCACCCACAGCAACGAGAAACCGTACGTCTGCAAGGCTCCCGGCTGTACAAAGCGCTACACGGATCCCAGCTCACTGCGCAAGCACGTAAAAACCGTTCACGGAGCCGAGTTCTATGCGAATAAGAAGCACAAAGGTTTGCCCCTGCACGATGCCAACTCTGGACTCGATAGGGAGAAACACAGGGACAGGGATGGtggacagcaacagcagcatcatcaactGCAAGAGCAGCACATTGATTCCAGTCCATGCAGCGAGGATATGCACTCTGGCAAGCCGGTTAGTGTGTCCAGTCCAAGTATCAAGTCGGAGTCGGACGCCAACTCACCAGGCCAACTGGCTGCACACGGCGGATCCTCATCAGCGTCCGATTGCATGATGCATATATACAGGCAGGATGATTTAAACAGTGCCACAGTGCCAACGCTGGACGAAGGTTGGCCCTATGACGACGACGTGGACGCTGCCGATCTGCCCATCGTGCTGCGAGCCATGGTCAATATTGGTGGAAACGGTAATGCGGCATGCGCCAGCGTTGGCGGCGCCCCCGCGGCCCGGCAGCGTTTTCGCAGTCGCCTGCAAACAAAGGTGATCAACTCGGGCAACTCGATGCTGTCCAATATACCAGAGAGCAATCGAGCCATTGGCATAATAGAGCTCAATCAGCGCATTACCGAGCTCAAAATGGAGCCGGGTACAACGCCCACAGCCCAGCGTCTGCCAGCGGGCAACTGCCACGGCACAGGCGGATTGCAACTAACCGAGTTGCACACTGGTGCACCATCGCAGTCGCAACCGGGCCATGGTCGATCAACTGCGATACAGCTCCAGATGCAGGTACAGCAGGGATACAGGGATACAACGCAtacggcagcagctgctctcCAGGCGAACCAGCGACGCGACAGCCAGAACTCGAACGCCAGCACCTACTACTGCAGCATGCCGAGCCGACGAAGCAGCCAGTCCTCGCAGTTGTCATCGATATCGACAATGAGAGCCGGTCCCGTATATAATACGCCATCCTTGTACGATCCCATATCACCGGGCTGCTCGCGTCGCTCCAGCCAAATGTCCAATGTGGTCACTAACATTAATGCTCAAATGTTGAACTACAACAATGCAAATGGGGCCCTCAATCCCTCGACGTCTGTATGCGGCGGAGTGGGCGGAGTTCAGTACATTTCCGGAACTGGGTCGCGCAACAGTAgcttgccgccgccgccgtcctCCCACCTGATTGCCACACACCTGCAGCGCCTGCAGTCGGTCGATGCCAGCGGCTATTATCAGAAAGCAAATATGAACCTCAATTCGAATCCAAATCAAAGGGTTGCGCAAAGTGGCGGTCGCTTCTCGATTCCGAACGTTCTTCAGTCACCGCTGAACTCAAATTACACCGGTGCATATGAGGAAGAGCCCATGGCCAATCACAGACGCCAGTCAGAGCCCATTATGGTCCAGCAGAGCTTGGAACGGATGGTGACATCGCCTGCTTTCAATACAACCTACCAGAACATACGCCAACAATCTGTCAGCAATGCCAATCATAGAAATCGAACGGATCCTTCGATTTCATCCAGTTGTTCGCCTGGTCAAAACAAGGAGTGTCCCGGCAGTGCCCCAGACGCCGTACGAGAGCATCATCCAAACGAAAAGGTTAATTTGGATGAGGTCGAAGAGTTAATATTGCCCGATGAGATGCTGCAGTATCTGAATTTGGTTAAGGAAACCGAGAAGCCGAAAGCGAAGGATCCCAAGACTGAAGAGGCAGCACCTTCCTTCGCAACCAATAATCCAGCATATCtcacggcagcaacaacacccacacccacacacaacacacccAGTTGTCCGTCTCCTCTAATGCAGCTCATGTCACCCCAATCGGGGCATACCATGTCAGCGATAGGTAGTCCATACTCCCAGCGCAATTACGAACCGGAAGGAGCCAACCAATCCTATCGTCATCAGCATACGGTCTACTGCACACAGAGACCCAATGAGTCGCCCATTAATGGGCCGCATGCTCAGTATCCGTATGTGACGGGCCAAGCTCCCGATTcagttccagctccagctccaacaCCGAATTCAGCTCAAGCCCTACCTGCAGGACAGCAGCCACCAAGCAGTTACGAGCCACAACCGACCACAACCCATCAGAATCAAATAATCGACTCTTCAATGACCAGTCTTCCGGAATTGGcgcctgttgctgcaactCCTGGAACGCAAATGAATCTTAATGCGTTGGACGCTGATCGAAAAGTCAACAGTGGCAATGAGATACAGTGCAGAGTCGTCAGCCAGTCCCAGTTATCGCCGACTGCTAATCTGAATGTCACATGTCCAGCGCACTTAACAAAGGCACCGATACAGAATCCTTGCTTACAGAGGCCCATTGATGGTGAACTGAACGCGCAGCCTTTAAGAGCGGAACCAAAAGTGGTGTCAGACCAGAACCAGCATCAGGCAGGCAACATGACTTCAATGCATTCAGACACTTACCAGCGTACACTGGAATATGTTCAAAGCTGTCAAAATTGGATGCAGACGAATAACAGCACTGTATTGATGGGACATGTCCAAGCGCCCGGTGTGGTAAATACGCCAGGAGCACAACAACATAACAACCCAATTTGGTCGGACGTGAGCAGCTCCACGCATCCGCATCCTAGCACAAATATGATTATCAACGATATGACAACATCTTTAAGCTCGCTCTTGGAGGAGAATCGATACCTTCAGATGATGCAGTAG
Protein Sequence: MDAYTLPTYFPLAYTELQFLASRRAAAAAAAASVLPSSPSSGNQVHITDVSSSVPVAASPLPPAVADSTLAPTLPPSPNGGAGSHTLLGSAGHHHHHHHHVHGHNVGVGMAGQSQQHDFHPAYRIPSYMEQFYSLQRTSPTASYHDPYANCPPAFHLAGLGLGSGEYLSARGMGSLSELHHAAVAAAAAAAAGSLASTDFHFSLDGNGRLGSPRPGGGGGGSMRASVSRKRALSSSPYSDSFDINSMIRFSPNSLATIMNGSRASSAASGSYGHLSASAISPIAHAHTTMAPHLQQLQAHLLRASAGLLHPITPQQAAAAAAASYSMSHVASAAALGLTDVSVKSKELTLATASQASTPTSTLISTAADESAIKPLGSNKNYDDGNIERPRATKSKSLELPSSTSESVAQVEADSASANLLERRQRNKSLAAHRVVSHDEGNEHAFNEYDCATADTTDIKDEPGDFIETNCHWRNCSVEFMTQDELVKHINNDHIQSNKKAFVCRWEDCSRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCYKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYVCKAPGCTKRYTDPSSLRKHVKTVHGAEFYANKKHKGLPLHDANSGLDREKHRDRDGGQQQQHHQLQEQHIDSSPCSEDMHSGKPVSVSSPSIKSESDANSPGQLAAHGGSSSASDCMMHIYRQDDLNSATVPTLDEGWPYDDDVDAADLPIVLRAMVNIGGNGNAACASVGGAPAARQRFRSRLQTKVINSGNSMLSNIPESNRAIGIIELNQRITELKMEPGTTPTAQRLPAGNCHGTGGLQLTELHTGAPSQSQPGHGRSTAIQLQMQVQQGYRDTTHTAAAALQANQRRDSQNSNASTYYCSMPSRRSSQSSQLSSISTMRAGPVYNTPSLYDPISPGCSRRSSQMSNVVTNINAQMLNYNNANGALNPSTSVCGGVGGVQYISGTGSRNSSLPPPPSSHLIATHLQRLQSVDASGYYQKANMNLNSNPNQRVAQSGGRFSIPNVLQSPLNSNYTGAYEEEPMANHRRQSEPIMVQQSLERMVTSPAFNTTYQNIRQQSVSNANHRNRTDPSISSSCSPGQNKECPGSAPDAVREHHPNEKVNLDEVEELILPDEMLQYLNLVKETEKPKAKDPKTEEAAPSFATNNPAYLTAATTPTPTHNTPSCPSPLMQLMSPQSGHTMSAIGSPYSQRNYEPEGANQSYRHQHTVYCTQRPNESPINGPHAQYPYVTGQAPDSVPAPAPTPNSAQALPAGQQPPSSYEPQPTTTHQNQIIDSSMTSLPELAPVAATPGTQMNLNALDADRKVNSGNEIQCRVVSQSQLSPTANLNVTCPAHLTKAPIQNPCLQRPIDGELNAQPLRAEPKVVSDQNQHQAGNMTSMHSDTYQRTLEYVQSCQNWMQTNNSTVLMGHVQAPGVVNTPGAQQHNNPIWSDVSSSTHPHPSTNMIINDMTTSLSSLLEENRYLQMMQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00547618;
90% Identity: iTF_00542006;
80% Identity: -