Basic Information

Insect: Drosophila paramelanica
Gene Symbol: HIVEP2
Assembly: GCA_035043915.1
Location: JAWNMO010000679.1:3833022-3841891[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0016 0.1 13.0 0.5 1 23 237 259 237 259 0.97

2 8 0.00032 0.02 15.3 2.9 1 21 265 285 265 289 0.89

3 8 0.045 2.8 8.5 0.2 1 19 929 947 929 950 0.93

4 8 2.8e-06 0.00017 21.7 2.0 1 23 1676 1698 1676 1698 0.99

5 8 1.2e-05 0.00074 19.7 5.3 1 23 1704 1728 1704 1728 0.92

6 8 0.0021 0.13 12.7 3.0 5 23 2178 2196 2175 2196 0.92

7 8 0.0058 0.36 11.3 2.5 1 23 2202 2226 2202 2226 0.91

8 8 0.0026 0.16 12.4 2.7 1 23 2247 2271 2247 2271 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0016	0.1	13.0	0.5	1	23	237	259	237	259	0.97
2	8	0.00032	0.02	15.3	2.9	1	21	265	285	265	289	0.89
3	8	0.045	2.8	8.5	0.2	1	19	929	947	929	950	0.93
4	8	2.8e-06	0.00017	21.7	2.0	1	23	1676	1698	1676	1698	0.99
5	8	1.2e-05	0.00074	19.7	5.3	1	23	1704	1728	1704	1728	0.92
6	8	0.0021	0.13	12.7	3.0	5	23	2178	2196	2175	2196	0.92
7	8	0.0058	0.36	11.3	2.5	1	23	2202	2226	2202	2226	0.91
8	8	0.0026	0.16	12.4	2.7	1	23	2247	2271	2247	2271	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCATGTGGCTAGCAGCGCCTCCAGCGTAGCCAcaaccaccaacaccaccagcagcagcagcagcagcagcaacattagcaaCACTGTGGCGCCAGTCAGCGCTGatgcggcagcaacagttgccgcagAAGCCATTGTCGATTGGCCAAACTCAAACAATTTGCGctatttgcacaaaaagttTAAGCGTTTGGCCAGCACCACCGAGCCGGAGACGGGCGATGTGGTGCGCACCACATCGCTCTCCTCGAACAGCTCGTTgtcgccaccgccaccaccgctgccaccgtcgtcgtcgtcgtcgtcgtcggttGCCCCATTGGTAAATGGACACATGACGTTGCTGCTGGCTAAAAATGAATTCAGTGCCACTTTCGtgaatgccaacaacaacaacaacaataataataacaataacaacaataacaacagccatgatgagagcaacaacaatagcagtaaaaatgttgctgttgctggtgggcCCAGAACACGCACACCgctcagcaacagcaacaataacaacagcaacaccagcagcaacagtaattATGCCAGCAATGCGACACTGTCGCCAGCAACATTcgcacagcatcagcaacaaacacagccaacgccagcagcagcagcaacaataacagtaacaacagcaacagcagcagcagtaacaacaacagcagcagcaacaactagtCGCTATGCGTGCCCCTTTTGCAACATGAACTGCGCAAAGCCATCCGTGCTGCAGAAGCACATACGGGCGCACACCAACGAGCGTCCGTATCCGTGCGACACCTGCGGCATCGCCTTCAAAACGAAGAGCAACCTCTACAAGCACTGCCGATCGCGTTCGCATGCGGCGCGCAGTCGCGGCTACGATGTGCCCGCCCACGAGGCGGACGGCATGTCCGATCAGGACGGCGACGGGGAgctgagcaacagcagctccgaGCTGCTAAGCGTCGAAGTGCTGAGTCGGGCGGATTCGCCTTTTGACGAGCCGATGGCCTCGCCAACGCCATCGCCATCGACGCTGTCGGCTGCGAAGAGCGCCTACTTGCAACAGCCGCCGTTGCCGCAGCAcatgcaacagctgccgctgggCTCGCCCGCTGCCGGCACACTGCCGCCCGCCACCGCCGACACGCTCCACTCGGCGACGGCGCAGCACCGCCAATCGTTCGACTACAAACCGTACAAGCCCAAGTTCCACAATGCGGCGCTCTATGCGCCGGGCAGCagcaaggagcagcagcagcagcagcaggttctgcaacagcagcaggcactgccacagcaaccacagcaaccgcatcaacagcagcaaaagctgccGCATCCAACATTGTTGGTGCATCCAACGCTTTCGCCCAGCACCCAGCTGAAGCTCAACAATCACATCAATTCGCatcagctgcaactgcagctgcaacagcagcagcagcagcaacaacagcagcaacaccagcagcagcagcagcagctgcacgtacagcaatcgctgctgctggccgctgctgctgctgccaatccCGTTGCTCTGCCAGCGCCGCCGCTCTCCCAGGGCGTCTACTATCTGAGCCAGCCGCCGCAGTATTTCAATCCCGCCACAGCTGCAATACACCAGCAGGCGCTCGCctttcagcagctgcagttacagcattttcagctgcagcagcaacaacagcaacagcagcagcagcaacatcaccaccaacaccaacaacagcaacatcaacagcagcaacattcgcCGCTGCTGAaggcgcagcaacagcaactgccacaaccgccgccaccaccgcagcagcagcagcTGGTCCGCTCGAATAGCCAACAGACGGCGATCACAGCGACTCCAGCAGCGCTGCCTgtgcctgccacgcccacagcaaCACCCACGCCCACTGCCAATCTGAGCAGCTttgccagcgccagcggcggcaTGCAAGTGAATGTGGAAAAGGTGCAGGAACACATCTCGAAGCTGATCTCACAGAACGAGGCCATTGTGGAGAACAAGGAGATTTTGCTGCAGAAGAAGTATCCCAAGCAGTTGAATCGTTCGCGCAGTTttaacaatgccaacaacaacaacaatagcagtgGTAATCTGACAACAGcgcacaccaacaacagcagcagcagcagcaacaacaacaacaatcagcaacTGGGCGAAACCAAAGTGAATCTGGCGCAGGTGATAgtacaaaaacagcagcagctgcatttgcagcaacagctgcaacaacaacagcagcagcagcaacaattccaaatgtatttgcaacagcagcaattggaGCCTGCCAATGGGCTGcacaagcgcagcagcagcagcagctcctccagcgGCTATGGCAGCCTCAAAGGTGCGCCCACCACAAATGtgaagctgccgccgccgccggcgccgctgccgctgcaaaCGCTGCAGTATCGCCAGGATCCGACAACACCTGTGCCCAagttggagcagcagcagcaactgcagcaaccgcagcagcagcaacagttgtcGGCGTCGAATCACGTGCAACCGCTAAATCTTTCGGCCAAAACGAAGCCAACAATGTCAACGaaaccagcagcaactgcaacaacagcagcagcagcagcgacaacaccagcaacaacaactgttgctgttgtggtgcCCAAGAGCACAGcaaccgctgctgctgcgccgccCAACAACTCGATCATCAAGAATCTGCTGTTGAACGCACGCGGCTTGGCCGTTCCCATTGGCGAGGGCGACGATGCCGTCTACTCGTGTCCCATCTGCGCGAACGAGTATCGCAGCGCGGACGAGCTGAAGCACCACAACAGCACCTATTGCCAGGACGCGAGCAGCAGTGCACCGATCAGTCCGGCCTCCTCGCCCGGCTCCAAGTTCTTTCGCTCCAATTCCATGTCGCTCAGCTTGCCGGAGCTCAAATCGCACATGGCCAACGTCAAGGAATGGTCAAAGAATCCCAAATCGCTGGCCAAGCTCGCCTGGTCCCAGCTGAAGACGAAGCCCAGCAGCCTCGTTCTGAGTAGGTTAAGTGCGGCGCAGTCGCCGGCGCgcacagcgacaacagcaacagcagcgagcagcagcaacagcaacaataacaatagcagcagcagcagcagcagcaacaacaccccagcaacagttgcagctagCATTCCGCCCAGCATCGATGCTGGCGTCGCTCTGCGCTTTGTGGACGCGCCGCTGCCATCGCCGGGTCCGCTGCTCGGCAAAACGCCGCTGGTGGATTATGCGGCGCCGCGCAAAGCGCCCGATGCCCAAGTGGTGATCACCAAAATGCACGAGGATCGGCTGGAGAACAGCGTCGGTGAGGCGGCCGCCAAGCGGCCCAAGCTGAGCAGCGACAttgccagctccagctccaattCCGGTTCGTCCTCGTTTCCGGCCGTTCAGCTGCTCTTTGGCGGCAATCAGGAGCTGCAttccgccgccgccaccgctggCATTTTCAGCACCAAGGAGGAGCGTCTGCGTCGCTTCACCTCCTCCGGCGGCACCATGATACCCATCTCCGAGTGCCCCGATCTGGACAAGAGCCCCAAAATGATACGCACCCCGCTGCTCTCCGGCGGCAGCTTCCAGGAGATGTCGCCACGGCTCAGCGACACCAAGGAACGCAAGCTGGCCAACAATGGCTACCTGCTCAGCGCCGCCGTCGCGAACAGCGCGAATCATTTCCAATATCCGCCCATCAATCCGATCACCGCCTTCAATCCGCTGACACTGCCAAGCTTAAGCGGCGATTCCGGCAAATCGATACCCTACGTGCCGGGCATACCGGGTCCGGGCAGCCtctcgctgctgccgccgccgccgcagcagctgccgcgcGGTCGCAGTCCCAATCGCAAGCAGCCCagtcccaatcccaatccgaattcgaattcgaatccGTTGCTGGCCGCTGCTGAGGCGCCGCTCAAGTCGCTGTCGCCGTTTGGCGGCGTCCAAAATTTGCCCAGCGAATTCAGTCGCCAGCCGCCGACGCCCGCTCAGCGCAATGCGCTGCAAtggaacaacagcaacaacagcaacagtagcagcagcagcaacaacaacaagacggAAACGTTGAGCAAAAAGCCGCCGTTTAATTTCCTGCGCATGGCGGATAACGTGAAAAGCGCGGAGGAAGTGCGTCACTTTAATTTCGATAGTGTGCACAAAACGCAGGAGGCGCTGGCGCCGCTGCACGTGGACACGCCCGAGGAGCtcgcacaaacaacaacaacaacagcagcagcaacagcagcaacaacaacagcaaccagtgCCAAATCAAAGTTTCTGCGACCGACCAGTTTGCCACTGAAGCCGGGCACATTTACGCCGAAACGTCATCACGGCATCACACCGACAGCGAATACCCTGCCGCTGATCTCACCGGAAACGCCGCGTCCATCGAAGTCGTGCGTGCAACTGTATTTGAATGGCCACGCCTATACGTATTTGGGTCTGAAGTGCAGCACCAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCGTCGTATGTGGCCGGCATGCACAAGCTGTCGATGTACAGTGTGTGGCAGGTGTGCGAGGAGAACCAGCCGCATCCGCTCGGCTTCAAGCCCAGACAGGTGATGGCCCTCTACGATTCCCGCCAGAAGATGCTCGGCGCCGGCTGCGCGACGGCCATGGCCGGCGCCGGGAAGCTGCACTATGCGCTGGTCAGCGCCCAGCAGACGGTCAGCAGCTGCTCGACGACTGCCAACGGACAGAACAAGTTctaccagcatcagcagcagcagcagctgcagcagcagcaggcgcaacaGTCGCCGAAGCAGCCGCCGGCGATTGGAGCGCTCAGCGAGGCGAACGTGGCCGCCAAGGCCAGCGAGGAGGCGGCGGCCAAGAAACTGGAGTCGAGCCAGCTGCTCGTCGGTGGCTACGAATCGCACGAGGATTACACGTACATACGCGGACGCGGACGGGGCCGTTATGTCTGCTCCGAGTGCGGCATTCGGTGCAAGAAGCCGTCCATGCTGAAGAAGCACATTCGCACCCACACGGACGTGCGTCCGTTCACCTGCAGCCACTGCAATTTCAGCTTCAAGACCAAGGGCAATCTGACCAAGCACATGCAGTCGAAGACACACTTCAAGAAGTGCATCGAGCTGGGCATCAATCCGGGCCCGATGCCCGCCGATGGCGAGTTCCTCGATGTCGATGTGGAGTTCGATCAGCAGTCATCGACATCCGCCGGCGGACGCACCTCCTCCATGGCCGGCGAGTCCGATTCGGAGGATTACAGCGACAACGAATCAGAGAGCAGCGACACCGACGAGTCGAAGTCGCGCATGAAGGAGCACGAGGCGGCGCGCGgtctgttgtcgctgtcgatgACGCCGCCGATACCGCAGAGCGTGTCGCCGTATCCGGCACAGCTGCAGGATGCGCCGGTGCCGGCGGGCAGTCCGGCCAATAGCATTGGCTCCTCGGCGGGCAGCGCGGCGGGCGGATCGCAGCCAAAGCGTTTGGTCTGCTCGTTCACGTCGCCGAAGCCGCCGTTCGATTACCAGAAACAGGAACAGTATTACTCAAATCCGGAGGAGTCGAAGCCCAAGCGGGGCGTGCCCAGCGACGAGAGCAGCGCCCCGATGGATCTAACCAAGCCGCGCAGCATGTCCGGCGGCCTGGCGCCCATCGAGCAGACGCTGCCCAAATCGCAGGCACAGCAGATGCGGGACGTGATCTTCGGAGCGGGCAACAACGAGTGCGGGTTCATGAAGACGCTGATCTCGGTGTCGGACAAGGTGCGCATCTCCGCCGAAATGGAGGAGCAGGCGAAGCGCAAAAGCGACGGCGATGACCTGCTGCTGCAGACCTACATCAAGGAGCAGGCGCTGCAGCACGCCAAAATGAAGCAGAGCCAGTTCAGTCGCAGCTACCTggtgaccagcagcagcgccaccagcaccaccaccatcagcaCCACCAtcaatgccacgcccattgtgAGCAGCTGCCTGCCGAAGCCAGCCGTGATCATCACGGAGCTGCCCAGCATCGAGGTGCACGAGGCGAAGACGCCCGAGCCGCCAGCGGCGAATCCCGTCGAGGAGGAAAGCGAGGCGTGCGAGGCACAGCCAAAAGTCGAAGCGGAGCAGCCCGCCAAGTTGGTGTCGGTGGTGCCGATGGCCAAGTCGGGAGTCGAACCGACGCCGCCACACAATGCCAATTTGCCCGCTGCAGTGCAGCAGCCGGATGCGACAGATTTCAGCGGCgtgctgagcagcagcaatggaCCCGCGCGCACTGTCATCGTCGGCGAGGAGGGCTTCAAGGcggcgccaacaacaacaacagcagcaacagcggcgatATCAACATCGACAACATCGACGAGCAGCGCCGGGGAGCAGCtgaccagcagcggcagctatCCGGGTCGTGTggtggcgccgccgccgccaattGCCAGCGACGGTCGTCCGACGTGCATCCTGTGCAACAAGACGTTCCAGCGCCAGCATCAGCTGACCCTCCACATGAACATCCATTACATGGAGCGCAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGGACGCACGGCCATCTGCAGAAGCACGAACGCTCCGAGGCGCACCGTAACAAGGTGATGATGACCTCGACGTTTGGGGTGCCAACCACATCGAATCCGCGCCCGTTCGAGTGCACCGACTGCAAGATCGCGTTCCGCATACACGGCCATCTGGCGAAGCATCTGCGCTCCAAGACGCACGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCGTTCGGCACCTATGCGGAAATCGAGCGGGCCGGCATCAGTCTGACGGACATCGATACCAGCGACTGCGAGAACTCGCTCATCTCGCTGAAGCAGCTCGCCCAGAAGCTGCTCGAGAAGGACCCGAACAAGCTGAGCGGCTACACGACGCCATCGGGCATGCTCCAGCTGGCCGCGGATGCGCCCGCCGCCGGCCAGGACAGCGCCTCCGAGGATGGGTTCAGTGCGGCCAACAGCGCCGCCGCCTCGGCAATAGCCTCCCTGGACAACGACAGCGCCGGCAACACGCCCCAACGGGCCAGCTCCATGTCCGAGGACGAGACGCTGACCAACGGCATCGGCCACAGCCACGGACACGGTCAGGGGCATAGCCTGAAGCGTCGCCTGCCcggcagcagcttcagcagcaACGGCGACGAGAGCGACAATCCGCTGGAGAGCAGCGTCGGCGAGAAGCGCGCCAGGAGCAACACCAACGAGCTGACGCTGCCAGTGGCCGCGTCCGCGTCCGCGGCCACCGCCAGCAACTGA
Protein Sequence: MTLQHVASSASSVATTTNTTSSSSSSSNISNTVAPVSADAAATVAAEAIVDWPNSNNLRYLHKKFKRLASTTEPETGDVVRTTSLSSNSSLSPPPPPLPPSSSSSSSVAPLVNGHMTLLLAKNEFSATFVNANNNNNNNNNNNNNNNSHDESNNNSSKNVAVAGGPRTRTPLSNSNNNNSNTSSNSNYASNATLSPATFAQHQQQTQPTPAAAATITVTTATAAAVTTTAAATTSRYACPFCNMNCAKPSVLQKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARSRGYDVPAHEADGMSDQDGDGELSNSSSELLSVEVLSRADSPFDEPMASPTPSPSTLSAAKSAYLQQPPLPQHMQQLPLGSPAAGTLPPATADTLHSATAQHRQSFDYKPYKPKFHNAALYAPGSSKEQQQQQQVLQQQQALPQQPQQPHQQQQKLPHPTLLVHPTLSPSTQLKLNNHINSHQLQLQLQQQQQQQQQQQHQQQQQQLHVQQSLLLAAAAAANPVALPAPPLSQGVYYLSQPPQYFNPATAAIHQQALAFQQLQLQHFQLQQQQQQQQQQQHHHQHQQQQHQQQQHSPLLKAQQQQLPQPPPPPQQQQLVRSNSQQTAITATPAALPVPATPTATPTPTANLSSFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNNSSGNLTTAHTNNSSSSSNNNNNQQLGETKVNLAQVIVQKQQQLHLQQQLQQQQQQQQQFQMYLQQQQLEPANGLHKRSSSSSSSSGYGSLKGAPTTNVKLPPPPAPLPLQTLQYRQDPTTPVPKLEQQQQLQQPQQQQQLSASNHVQPLNLSAKTKPTMSTKPAATATTAAAAATTPATTTVAVVVPKSTATAAAAPPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEYRSADELKHHNSTYCQDASSSAPISPASSPGSKFFRSNSMSLSLPELKSHMANVKEWSKNPKSLAKLAWSQLKTKPSSLVLSRLSAAQSPARTATTATAASSSNSNNNNSSSSSSSNNTPATVAASIPPSIDAGVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENSVGEAAAKRPKLSSDIASSSSNSGSSSFPAVQLLFGGNQELHSAAATAGIFSTKEERLRRFTSSGGTMIPISECPDLDKSPKMIRTPLLSGGSFQEMSPRLSDTKERKLANNGYLLSAAVANSANHFQYPPINPITAFNPLTLPSLSGDSGKSIPYVPGIPGPGSLSLLPPPPQQLPRGRSPNRKQPSPNPNPNSNSNPLLAAAEAPLKSLSPFGGVQNLPSEFSRQPPTPAQRNALQWNNSNNSNSSSSSNNNKTETLSKKPPFNFLRMADNVKSAEEVRHFNFDSVHKTQEALAPLHVDTPEELAQTTTTTAAATAATTTATSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPRQVMALYDSRQKMLGAGCATAMAGAGKLHYALVSAQQTVSSCSTTANGQNKFYQHQQQQQLQQQQAQQSPKQPPAIGALSEANVAAKASEEAAAKKLESSQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGESDSEDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPAQLQDAPVPAGSPANSIGSSAGSAAGGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPSDESSAPMDLTKPRSMSGGLAPIEQTLPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEMEEQAKRKSDGDDLLLQTYIKEQALQHAKMKQSQFSRSYLVTSSSATSTTTISTTINATPIVSSCLPKPAVIITELPSIEVHEAKTPEPPAANPVEEESEACEAQPKVEAEQPAKLVSVVPMAKSGVEPTPPHNANLPAAVQQPDATDFSGVLSSSNGPARTVIVGEEGFKAAPTTTTAATAAISTSTTSTSSAGEQLTSSGSYPGRVVAPPPPIASDGRPTCILCNKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTHGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTDIDTSDCENSLISLKQLAQKLLEKDPNKLSGYTTPSGMLQLAADAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETLTNGIGHSHGHGQGHSLKRRLPGSSFSSNGDESDNPLESSVGEKRARSNTNELTLPVAASASAATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496082;
90% Identity: iTF_00541961;
80% Identity: -