Basic Information

Insect: Drosophila paramelanica
Gene Symbol: -
Assembly: GCA_035043915.1
Location: JAWNMO010000495.1:2724747-2725983[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.32 20 5.8 1.7 1 23 153 175 153 175 0.96

2 8 2.3e-05 0.0014 18.9 1.6 1 23 180 205 180 205 0.97

3 8 2.6e-05 0.0016 18.7 2.9 1 23 214 236 214 236 0.97

4 8 2.8e-05 0.0018 18.6 0.4 1 23 244 268 244 268 0.98

5 8 0.0048 0.3 11.6 1.2 1 23 274 296 274 296 0.97

6 8 1.1e-05 0.00068 19.9 4.6 1 23 302 325 302 325 0.97

7 8 0.0013 0.083 13.3 2.3 1 23 333 355 333 355 0.94

8 8 0.0031 0.19 12.2 1.5 1 16 361 375 361 381 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.32	20	5.8	1.7	1	23	153	175	153	175	0.96
2	8	2.3e-05	0.0014	18.9	1.6	1	23	180	205	180	205	0.97
3	8	2.6e-05	0.0016	18.7	2.9	1	23	214	236	214	236	0.97
4	8	2.8e-05	0.0018	18.6	0.4	1	23	244	268	244	268	0.98
5	8	0.0048	0.3	11.6	1.2	1	23	274	296	274	296	0.97
6	8	1.1e-05	0.00068	19.9	4.6	1	23	302	325	302	325	0.97
7	8	0.0013	0.083	13.3	2.3	1	23	333	355	333	355	0.94
8	8	0.0031	0.19	12.2	1.5	1	16	361	375	361	381	0.75

Sequence Information

Coding Sequence: ATGTCCATTTCGTCCAAGTGCCGTGTGTGCATTTGCTCGCTCGATGCAGCTGCCGCATCCTTCGACATGCGAAAACTGCCCAAGCTGGCGCACAAGTTTGTCACCTGTACGGATTTGTCCTTGTCCGACGAGACCCGTCTGCCCAGTGAACTGTGCCAAGCGTGCCACGATCAGCTGGATCGGCTGTACACATTCCGGGCCAAGTGCATAGCTGCCGATACAAGATGGCGTATGGAGATACTGGCTTTTTGCGATGATGAAGTCAGCAAGGATGCGGAGGCACCAACGGAACCGGAGGGAGTCCAGGAACTGCAACAGTGCAATGTGGAGGAAAACACAAACCTGCAACAGAGAGCTAATGCAACAGGTGAAACGGAAACACCGGCACACCTGCCGGAATCCAGCTCGGAACCGGTTGTTGAACAGAGCCCCTCGTTGCCACAGTCAAAAGCCATCTACAAATGCGACATCTGCGCCACGCAGTTCCTCGAGGAGCATCGTCTTCAGGCGCATAAACGTCAGCATGGACTGATGCCGTACCCGTGTCCGGAGCCGGGCTGTGACCGCGGCTACAGCCACAAAAACACGCTCAGCGTGCACATGCGCAAGTGCCACAAGCTTGGCAAGGAGCACAAGTCGCACGTCTGCGAGTACTGCGGCAAGACGTTCGACACTCTCTGGCGGCTGAAGAACCATCGCTTCACGCACAAGGACAAATCGGAGCTGCCGTATGTGTGCGAGGTGACGGACTGTGCGCAGCGCTTCTCCAGCAAACAGCTGCTCAAGGTGCACATGATGCGTCATGCGGGAATCAAGAACTACAGCTGCACCTACTGCGGCGTGCAGAAGACGACGCGCACCGAACTGAAGATTCACCTCAACTACCACACGCTGGAGCGCACCTACTGCTGCCGCATCTGCTCGAAGGTGTGCAACAGCTCCAGCAATCTCAACCTTCACATGCGCAGCGTCCACGAACGTGATCGTTCGCGCAGCTATGCCTGCAGCTACTGCGATCGCAGCTTCACCCAACCGTTCCTCTGCAAGCAGCACGAGCTCATCCACACCGGCGAGAAGCCGCACGAGTGTCCGGACTGTGGCCGACACTTCCGCCAGAAGGCGCGTTGCGCACACATCGCAAGATCCACGAGCGGGAGAGCAGCGAAGCACCGATAA
Protein Sequence: MSISSKCRVCICSLDAAAASFDMRKLPKLAHKFVTCTDLSLSDETRLPSELCQACHDQLDRLYTFRAKCIAADTRWRMEILAFCDDEVSKDAEAPTEPEGVQELQQCNVEENTNLQQRANATGETETPAHLPESSSEPVVEQSPSLPQSKAIYKCDICATQFLEEHRLQAHKRQHGLMPYPCPEPGCDRGYSHKNTLSVHMRKCHKLGKEHKSHVCEYCGKTFDTLWRLKNHRFTHKDKSELPYVCEVTDCAQRFSSKQLLKVHMMRHAGIKNYSCTYCGVQKTTRTELKIHLNYHTLERTYCCRICSKVCNSSSNLNLHMRSVHERDRSRSYACSYCDRSFTQPFLCKQHELIHTGEKPHECPDCGRHFRQKARCAHIARSTSGRAAKHR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00506314;
90% Identity: iTF_00589029; iTF_00598372; iTF_00547530; iTF_00561212;
80% Identity: -