Basic Information

Insect: Drosophila paramelanica
Gene Symbol: grau
Assembly: GCA_035043915.1
Location: JAWNMO010000674.1:2970618-2972598[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 9.1e-07 5.6e-05 23.3 0.2 2 23 298 319 297 320 0.94

2 8 3.2e-06 0.0002 21.5 0.9 1 23 328 350 328 350 0.96

3 8 0.092 5.7 7.5 1.5 1 23 358 383 358 383 0.90

4 8 0.0013 0.083 13.3 0.5 2 23 389 410 389 410 0.97

5 8 0.066 4.1 8.0 0.2 2 23 419 442 418 442 0.86

6 8 9.5e-05 0.0059 16.9 2.0 1 23 449 472 449 472 0.96

7 8 7.6e-06 0.00047 20.4 0.8 1 23 477 499 477 499 0.97

8 8 6.7e-05 0.0042 17.4 3.6 1 23 505 528 505 528 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	9.1e-07	5.6e-05	23.3	0.2	2	23	298	319	297	320	0.94
2	8	3.2e-06	0.0002	21.5	0.9	1	23	328	350	328	350	0.96
3	8	0.092	5.7	7.5	1.5	1	23	358	383	358	383	0.90
4	8	0.0013	0.083	13.3	0.5	2	23	389	410	389	410	0.97
5	8	0.066	4.1	8.0	0.2	2	23	419	442	418	442	0.86
6	8	9.5e-05	0.0059	16.9	2.0	1	23	449	472	449	472	0.96
7	8	7.6e-06	0.00047	20.4	0.8	1	23	477	499	477	499	0.97
8	8	6.7e-05	0.0042	17.4	3.6	1	23	505	528	505	528	0.98

Sequence Information

Coding Sequence: ATGGAACCACAAATTTGTCGCCTTTGCCTGCGTGGCTGTGGTTCCCAGATGTGCCTGCCAATCTTTTGTAGCGAAGCAGGTGTCGCAGGTGCAGAAGGTAACGTGCCAAATGTTGCTGAAGTTCTGCGCCAGCACTTTTGGTTCGAGGTATTGCCAAACGATTTAATATCGAAAGTTGTGTGTAATGTGTGCTGGACACAGGTCTCAGAGTTCCATCAGTTCTATGTTTCCATACAAGAAGCTCAGTTAATCTACGCGAACGCGCCGAAATTTAAACAAGATCCCGATCCAGAAATGATGAACACATCATGGCCAGAGGAAGTAATGATGCCGGCTGAAGAGCTGACGGTGGATGCGGAAGCAAATACCGATTGCACCAACACTCAGCTGAATGTGAATCCCTTAGATGAACTAGATCTGGAAATATCAGCGTATGCCCATACTGTCGCCGAAAGCAAGCTAGACATCAAGCTTGAGAGACTTACGCCCGACGAGTTTACTCACGAATTGGAGGATGTGGACGTTATTGTAACCCGAAGTGGTCGCAAGCGAAAACGTGAAACGGAAACAATTGACCGGGTGAAGGGAGCCAAGGCGAAAAAGGCCGCACAGACCAAAGGCCACGAAAAGCGCAAATTCGCCACAAAGAGCACTTTTAAGAAGCAGCAGTGGCCGCCGTTTTGCAAAGAGGATGAAGATCTAATTAAACGTTACATTGTAATGGGCTGTGAACTTTGCATTTTCCTAGCGGATGACTTCGACGGCATCCGAGATCATTTCAAAGAGAAACACGCCAGCGAACGGCCCTACGTTAAATGCTGCGGGCGAAAGTTGAACAAACGTTGCCTTATTGTCGAGCATGCCAGGCGTCACGAGAATCCCGAATATATTAAATGCAACGATTGCGGAAAAGTGTTTGCCAATTCGAGCGTGTTGCGCGCCCATTGGCTGGTACACCACGTGCCTGACGAGGAATGCGACTTCCAGTGCGACGAGTGCGGCAAGCGATTCTCGCGCCGCAATCTCCTGGAACTGCACAAGGGTTCGCATGTGCCAGCCCATGAGCGCAAGTTTATCTGTCCAGAATGCCCCAAACATAATGCCTTTGCCACCGAATACCACATGCAGGTTCACATTAGCATGCAGCACCGCAAGGCGGCCAACGTGTGCCATGTGTGCGGGAAGGAGATCAAGGATAAGGCTGTCTTTGAGAAGCACGTCCGGCTGCATTTCGAGGAAAGCGGGCCGCGCATTAAATGCCCCCGGCCCGACTGTGAAAGTTGGCTTAAGGATGAGGATAATTTAAAGCAGCATTTAAGGCGCCACAACGACGAGGGCAAAACGTTCATTTGCTCAGAATGCGGCAAGAGTTGCAAGAACTCGCGCGCCCTAATTGGACACAAGCGTTATTCGCACTCAAATACAATCTACACGTGTGAGCAGTGCGGCAAGACCTTCAAAAAAGATATTAGCCTTAAGGAGCATATGGCTCAGCACACTGGAGAGCCTCTATACAAATGTCCTTTTTGCCCGCGGACATTCAACTCGAATGCTAATATGCACTCGCACAAAAAGCGGATGCACCCAGATGAATGGGATCACTGGCGTAAAACGAAAACGGGTAGCTCCCAAAAGGTGCTTCCCAGTGCCCAGGTCTCGCAAATGTTCAGAGAAGACACTGAAACATGCGCCATTCCGAATATTTCAAACGTATTTTAG
Protein Sequence: MEPQICRLCLRGCGSQMCLPIFCSEAGVAGAEGNVPNVAEVLRQHFWFEVLPNDLISKVVCNVCWTQVSEFHQFYVSIQEAQLIYANAPKFKQDPDPEMMNTSWPEEVMMPAEELTVDAEANTDCTNTQLNVNPLDELDLEISAYAHTVAESKLDIKLERLTPDEFTHELEDVDVIVTRSGRKRKRETETIDRVKGAKAKKAAQTKGHEKRKFATKSTFKKQQWPPFCKEDEDLIKRYIVMGCELCIFLADDFDGIRDHFKEKHASERPYVKCCGRKLNKRCLIVEHARRHENPEYIKCNDCGKVFANSSVLRAHWLVHHVPDEECDFQCDECGKRFSRRNLLELHKGSHVPAHERKFICPECPKHNAFATEYHMQVHISMQHRKAANVCHVCGKEIKDKAVFEKHVRLHFEESGPRIKCPRPDCESWLKDEDNLKQHLRRHNDEGKTFICSECGKSCKNSRALIGHKRYSHSNTIYTCEQCGKTFKKDISLKEHMAQHTGEPLYKCPFCPRTFNSNANMHSHKKRMHPDEWDHWRKTKTGSSQKVLPSAQVSQMFREDTETCAIPNISNVF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496062;
90% Identity: iTF_00530432;
80% Identity: -