Dpar007180.1
Basic Information
- Insect
- Drosophila paramelanica
- Gene Symbol
- -
- Assembly
- GCA_035043915.1
- Location
- JAWNMO010000557.1:1622703-1627803[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.068 4.2 7.9 0.1 1 19 348 366 348 369 0.80 2 8 6.5e-05 0.004 17.4 0.7 3 23 748 769 746 769 0.96 3 8 0.00076 0.047 14.1 3.3 1 23 791 813 791 813 0.97 4 8 1.1e-05 0.0007 19.8 2.2 1 23 819 841 819 841 0.96 5 8 4e-05 0.0025 18.1 0.9 1 23 847 869 847 869 0.98 6 8 0.00072 0.044 14.1 1.3 1 23 875 897 875 897 0.98 7 8 0.0016 0.098 13.1 0.0 2 23 904 925 903 925 0.96 8 8 0.015 0.9 10.0 0.2 3 21 933 951 931 952 0.94
Sequence Information
- Coding Sequence
- ATGACGCCAGCTGCTGTGATAGCTGCTCCCGTtgaggaggagcagctgcgtcGGCGCTGCGGCGCCGTCTACGCTTGGAACTGCGCCGGGGAGCTATACGGCATCGAGTGCGAACTGTGCGAGGAGCGGCCACTCTGCGCCCTCGATGAGTTCGCGGAGCACATGGAACTGTGGCATCCCGACTGGCAGCAGGCGCCCGTCGATGAGCTGATGCTCGAGGTGCTCGCCGAGCAGTCCAGCGGCGGCGAGGTCAACGAACTCAAACAGCAGCTCGTCCAAGAGCTGAACGCCCTCGACACCGGCCACGCCCCCCAACTGCACGAAACGACGCAACTGCTAAACGACAACATCAAATTCGATGGCAATGCCGCTCTGCCCGCCGTGGAGGCGCCGAAGCTGAGCACACAGCACGTCCAGCATCTGATCGAGCTGTACGAGGCGCAGCCGCGTTTGTGGGACCAGTCGCATCCGGAGTTCCGGGACGTGGACCGGGGCAGGGAGTCGTGGCGGCAGATAACCGATGCGTGGAGCGCCTACTGCGGCCGCCGCTTCACGGTGACGGATGTGCGCATCCGGATCTCGACGCTGTGCCAGCGGTTCCTCAAGCAGCGCGACCGAATCGCCGCCGAAGGGGAGCTGGAGGAGTCGATCAAGTTCGTGCACTACGACCAGCTGCGCTTCCTGTGCGCCCAGCAGTCGCTGCTGAAGCGCCAGGAGCACTACTCCCGGGAGAACCGCAAGCTGCTCGAGTTCTACGAGCACTATCCGATCCTCTGGCACAACGCCCACAAGCGGCTGCGCTGCGCGGAAACGCTGCGGGCCCGGCACGAGGCGCACCGGGGtctgcagctggcgctgcgcaTGTGCGGGATTCGGATGTCCGGACTGGCGATGCAGCGTCGGCTGCAGTCGCTGCGGAAACGCTATCGGCTGGAGAAGATCCGCTTTCTGCACAGCGTCGTCGAGGGCAAACAGGCGGAATTTGTGTCGGGCTTTGAGCACTATGCGGAAATGGAATTTCTGCACAAGCACATCGATCCGTATGTGTGCGCCGGATGCGGCAAGATCTTTGAGAATCTGGTCAGCCATCGGGCGCACGTGGAGAGCAGCTGCGAGGAGCAGAAATCGAAGCCGGGTCGGGAACGGGAaggggaacgggaacgggaattGGTACCGGAACAGGAACAAACAGAGGCAACGGTGGGTGAACTGATGGCGCTCATGGAGAATGGCATGGatgaggagcaggagcaggagcagttGCAGGAGCAGGCGGAGAAACTGGATTTGGAGCCGGAGCAAGTGCAGCCGGTCGAAGTGAAGCCGGAGCAGCAACTGGAATCGGAACTAGGAGTGAAGCAggagcaagtgcagcagccgGTCGAAGTGGAGCAGGAACAGCTGGAAATGGAGCAGGCGACGGAGCCAACGGTCGGTGAGCTGCTGACCCTGATGCAAATGGAGCAGCCACACCGCGAGAACGACCGGGATGAGTATGAGGAGGAGAGCGCCTCCGAGGAGCCGCTCACCGAGCTCAGCTCCAATTCGGAGCACAGCCTCCACCGGCCGCTGCGCACCCGCCTCAGCCTGGAGCTGACCCACCGGCTCATCGAGCTCTACCAGGCGCAGCCGAATCTCTGGGATCCCAATCACCTCGATTACAATGGCCGCCGGCAGCGGCGTCAGTCGTGGCACACCATCGCCGCCCAGTTGAATGCGGCccaggggggcgtggcacgttACAGCTGGCAATCGCTGCACCGCAAACTGACCGACTACATCAAATACTACCGcagggagcgggagcgggaggCGCTCGCCGAGGTCGGCGCCGGGGAGGGCACGCGCTGGGGCTTCTACGAGGCGTTCAGCTTCCTGGACGACGTGGTGCCCATCAATTGCGCGCTGCAGAagacgctgcagcagcgcgaCAGCAACCTGAAGATCATCCAAATCTACCAGAGCTACGAGCAGCTCTGGTGCACCGATCACCCGGACTACACCAAGCGCAAGCAGCGTCTCCGCCAGCTGGAGTCCCTGTGCACCCGCCTGCAGGAGGAGTGCAACCTGCAGATCAGCGTCGAGCGTCTCAAGAGCCGCCTCATCGAGTTCCGCTGCCAGTACAGACAGTGCAAGGCGGCGCGCCAGGCGGCCGTCAAGCGCGGCGATCTCAGCTGGCAGCCGGACTACGAATATTATCGTCCGCTGCAGTTTCTCGAGCTGCACGTCAGCCCCTTCGGCTGCGGCCAGTGCCCGGCCAGCTTCAAGCGGCGCAGCGATTTTCTGCGCCATCAGCGCAACGTTCACCAGTCGCAGCCGAAACAGCTGCGGCGACGTCGCGGCCAATCCGCGTCGGTGAATCCCGTCGAGCATATTTGCCACATTTGCGCGATGAGGTTCTCGCTGCGCACCAGCTTGCAGGCGCATCTCCGGCGGCATCTCGGCCAGCGGACGCACGCGTGCAGCGAGTGCCCCAAGATGTTCTTCAATTCGACCTCGCTGCGCGTCCATCAGCGCAGCCACACCAAGGAGCTGCCCTATGTCTGTGAGCACTGCGCCCGCGGCTTTGTCAACGCCAGCAAACTGAATCAGCACGTCAAACGGCACACGGAACAGCGTGACTATCCGTGCTCCAGGTGCGACAAGGCCTTTTATACCGCACACGAACGGGATCGACACCTGCGCGCCCATCTCAACATTCGGGATAAAGTTTGTCCGTATTGCGGCCGCGCCTTTGTCGTCGGCAGCGCCTACTACGCCCACCTCAATCTCCATCGCGGCGAGAAGCGGTACGGCTGCGCCAACTGCGGCACCCGGTTCGCCCAGTACGCCGGACTCTACAAGCATCGGAAGCGCTGCACCGCCTCCGAGGcggcaaaataa
- Protein Sequence
- MTPAAVIAAPVEEEQLRRRCGAVYAWNCAGELYGIECELCEERPLCALDEFAEHMELWHPDWQQAPVDELMLEVLAEQSSGGEVNELKQQLVQELNALDTGHAPQLHETTQLLNDNIKFDGNAALPAVEAPKLSTQHVQHLIELYEAQPRLWDQSHPEFRDVDRGRESWRQITDAWSAYCGRRFTVTDVRIRISTLCQRFLKQRDRIAAEGELEESIKFVHYDQLRFLCAQQSLLKRQEHYSRENRKLLEFYEHYPILWHNAHKRLRCAETLRARHEAHRGLQLALRMCGIRMSGLAMQRRLQSLRKRYRLEKIRFLHSVVEGKQAEFVSGFEHYAEMEFLHKHIDPYVCAGCGKIFENLVSHRAHVESSCEEQKSKPGREREGERERELVPEQEQTEATVGELMALMENGMDEEQEQEQLQEQAEKLDLEPEQVQPVEVKPEQQLESELGVKQEQVQQPVEVEQEQLEMEQATEPTVGELLTLMQMEQPHRENDRDEYEEESASEEPLTELSSNSEHSLHRPLRTRLSLELTHRLIELYQAQPNLWDPNHLDYNGRRQRRQSWHTIAAQLNAAQGGVARYSWQSLHRKLTDYIKYYRREREREALAEVGAGEGTRWGFYEAFSFLDDVVPINCALQKTLQQRDSNLKIIQIYQSYEQLWCTDHPDYTKRKQRLRQLESLCTRLQEECNLQISVERLKSRLIEFRCQYRQCKAARQAAVKRGDLSWQPDYEYYRPLQFLELHVSPFGCGQCPASFKRRSDFLRHQRNVHQSQPKQLRRRRGQSASVNPVEHICHICAMRFSLRTSLQAHLRRHLGQRTHACSECPKMFFNSTSLRVHQRSHTKELPYVCEHCARGFVNASKLNQHVKRHTEQRDYPCSRCDKAFYTAHERDRHLRAHLNIRDKVCPYCGRAFVVGSAYYAHLNLHRGEKRYGCANCGTRFAQYAGLYKHRKRCTASEAAK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00561229;
- 90% Identity
- iTF_00541920;
- 80% Identity
- -