Basic Information

Insect: Drosophila paramelanica
Gene Symbol: L
Assembly: GCA_035043915.1
Location: JAWNMO010000674.1:4681310-4690408[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00067 19.9 2.9 1 23 166 188 166 188 0.98

2 17 0.37 23 5.6 6.2 1 23 194 216 194 216 0.97

3 17 1.8e-07 1.1e-05 25.5 3.2 1 23 222 244 222 244 0.99

4 17 1.3e-05 0.00081 19.6 0.4 1 23 250 272 250 272 0.99

5 17 0.013 0.82 10.2 0.2 2 23 346 370 345 370 0.92

6 17 0.00085 0.053 13.9 0.2 2 23 398 420 397 420 0.95

7 17 0.11 7 7.2 0.4 1 23 500 522 500 522 0.95

8 17 0.023 1.4 9.4 0.1 2 23 530 551 529 551 0.91

9 17 0.00025 0.016 15.6 0.2 1 23 559 583 559 583 0.94

10 17 5.3 3.3e+02 2.0 0.9 2 23 619 641 618 641 0.94

11 17 0.0027 0.17 12.3 1.1 1 23 697 720 697 720 0.97

12 17 0.0068 0.42 11.1 1.6 2 23 895 917 894 917 0.96

13 17 0.12 7.5 7.1 0.1 1 23 923 945 923 945 0.92

14 17 1.5 91 3.7 1.2 2 23 953 974 952 974 0.93

15 17 0.42 26 5.4 1.2 1 23 1075 1097 1075 1097 0.94

16 17 0.032 2 8.9 0.0 1 23 1107 1129 1107 1129 0.95

17 17 0.0008 0.05 14.0 2.0 1 23 1134 1156 1134 1156 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00067	19.9	2.9	1	23	166	188	166	188	0.98
2	17	0.37	23	5.6	6.2	1	23	194	216	194	216	0.97
3	17	1.8e-07	1.1e-05	25.5	3.2	1	23	222	244	222	244	0.99
4	17	1.3e-05	0.00081	19.6	0.4	1	23	250	272	250	272	0.99
5	17	0.013	0.82	10.2	0.2	2	23	346	370	345	370	0.92
6	17	0.00085	0.053	13.9	0.2	2	23	398	420	397	420	0.95
7	17	0.11	7	7.2	0.4	1	23	500	522	500	522	0.95
8	17	0.023	1.4	9.4	0.1	2	23	530	551	529	551	0.91
9	17	0.00025	0.016	15.6	0.2	1	23	559	583	559	583	0.94
10	17	5.3	3.3e+02	2.0	0.9	2	23	619	641	618	641	0.94
11	17	0.0027	0.17	12.3	1.1	1	23	697	720	697	720	0.97
12	17	0.0068	0.42	11.1	1.6	2	23	895	917	894	917	0.96
13	17	0.12	7.5	7.1	0.1	1	23	923	945	923	945	0.92
14	17	1.5	91	3.7	1.2	2	23	953	974	952	974	0.93
15	17	0.42	26	5.4	1.2	1	23	1075	1097	1075	1097	0.94
16	17	0.032	2	8.9	0.0	1	23	1107	1129	1107	1129	0.95
17	17	0.0008	0.05	14.0	2.0	1	23	1134	1156	1134	1156	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTGGAGAACTTAATTGAAAAGATTCAAGCCACCAAGGAGATTACAAATAACGATATGTACAGCACGCACACCTCCTCCAGCTATTCGCCAAGCATCTCGGATGGAACTCTGACGCCCAATTCGATGCCGCAGCTGGCGGCGCAGGGCGACGAGTCCACCGCGGAGACGAAGGCGAATGGGGAAACAGTGTCCGCCAcggaggagcaacagcagcagttgcagcaggaGCCAATTAGGCCAAAGCGGCCGGCACAtttgcatcatcatcatcaccatcattatcatcatcagcaggCGCTGAAAATTGCCAACAAGCTGCGGAAAATCAATAAGGACGCAAAATTGCTAACCGGAACAGGATCGGGCGGCGCAGGACAGCCCGGACACAATGCAGCGGGAGCCAAGTTTGATAAGTTGACAGGCGAGGGCATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGTTGTTCAAACACAAACGCTCCCGAGATCGCCATAAGAAACTGCACACGAACGAAAGGAACTACAAGTGTCCGCACTGTGAGGCGGCTTTCTCCAGAAGCGATCATCTGAAGATTCACATGAAGACGCACGACATCCAGAAACCGTTCCAGTGCAGCATGTGCAATCGCGGCTACAACACGGCCGCCGCACTCACCTCGCACATGCAGAAGCACAAGAAGAACGCGGCCATTCTGGCGGCTGGCGGTAATCCGAACGCGCTCAACTACAGTCCAAGATCGACGGGCTCCGCTTCCATATCGAGCAATGGGAGCCTCCACAAGCGCCGCTATGCTTTAGCCTTGGCCACCGACAGCAGTCCGAGTCGCCTCGAGTTTCCGAAACGGTCGCGTGCTCAGCTGgcggctgccacgcccacaccgacACCGCTGCTGCGCTGCAGCTACTGTCCCAAGGTGACGGAGTTCACCAGCCTCGAACAGCTGAATGCCCATCTGCAGAGCGtccacgagcagcagcagcagcagcagtcgccaCCGGGCGATGGCGATGGATCCAACGTGGAACAGGCAACTAACGGTTTTCAGCTGAGCTGCGAATATTGCACGATGAAATTCGTGAATATCGCCGCACTCTTCCAGCACATGCGCGGCACCCATCTCGATCGGCTGAGCAGCCCGAACTCGTATTACGAGCACTTCAATCGGCTGGCCACGGCGGGCACTTTCAGTCCACGTTTGGCGCTGGAGATGCCCAAGCAAATCAAACAGGATGCGGATGCCAAATTGGAGCAACAGGAGCTGCCAACGGATTtgagcagcaacaagcggCGTCCGTTGACGCCACAATCAACATCAGCATCCGCATCAgtgccagcgccagcgccacctGGCGTCTTTCTGTGCAACCAGTGCAATGCCGGTTTGCCGGACTTTGAGAGCTTCCGCAATCATCTGAAATCGCACATTGTGGAGGGGATGCAGCTCAGCTGTCCGCACTGCGGCCTCAATCTGCCCGAGCAGAGCGAATACGAGCGACACGTGGTCGCCCACTTTCTGATCAGCAGCTCCGAGTTCAAttgcagcgccagctgcggCAAATCATACTCCAAAGCGGAGGAGCTGCAACAGCATCTGCTGAGCGAACAtgtccagcagctgctgaagtGCGTCCTCTGCTCGGAGCTGTGCGAGAATCGGATGTCGATGCAGCTGCATCTGGCCTGCGCCCACAGCCAGGAGACGAAGCTGTTGCGCTGCAGCGCCTGCCTCGAGCTGTTCCGCAGCGATGCCGAGTTCCATGTGCACGTCAAGACGCGACATCAGCTGGgcggacagcaacagcaacgggagcgggagcgggatcagcagcagcagcagctgagcggCGGCGGCCCATCCTCGAATCCGTTGCAGTGCATGTTCTGTCGCGTTGTTTGCGCCTCGGAGCTGGAGATGCATTTCCATTTGGCGGCGCATGCGCGACAATTTCGCTGTCCCAGCTGCCCGGAGACATTTCACGTGGAGTTCCTGCTCGATCGGCATATGCAGAGCCAacacggcggcggcggcggtggcgccaTCAAGGGAGCCAAGGAAACGGGCGCGGCTGCCGCCAGCATGGGCAGCCTCTATGTGAatgcgctgctgccgccgctggcagcggccgctgctgctgccgccgcggcgacaaacaacaacagcaacctgCACATCGACTACAATGTAGCGTTCAAGGGTCTGTTCGGTGGCggcaatgccacgcccacaaatcAACAGGCCAAATTCTACAGTCCGCTGCAGGTGGACACCAAAGCGACGCAGCCGGCGCCACATCCGGCGCTGATGTACGGCCTGAGCCAGCGCTATTTAATGGAAATGTACGCGGCGAAAGCGAATTCGCCGGCAACCAGCGCAGCCGAGTTGCCGCCACAAGCGACACCAATTGTGGCAGGCGCCAGCGGCGGCGCTGCTGCCACCAACTACAGTTGCGGGATGTGCGAGCGTCAGGATTTGCGCAGCGAGGCCGAATTGCATTCGCACCGGAAGCTGGCGCACAATCTGAAGACGGGCGTCAGTCTGCGGTGCGCCTACTGTTCCGGCAACTACAAGTCGCGGGCGGAACTGGAGCAGCACATGAAGAGCTGCCACAATTCGAGCGGCAAGCACAAGTGTCTCATCTGCGATGAGATCTTCCCCTCGCCGGCGATTCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCGGGCAAATGCGCCCACTGCGGCCACCAGCTGGAGCACGTGGCCGCCTTCCGGGCGCACCTCGGCGAGCACGGCAACGACGGCAATCTGCCGATGGCCTGCATCTGCTGCCGGCAAACGCTCCACTCCGAATTCGAGCTGAGCCTGCACGCCAAATTCCACACGAAATCGTCGCCGGGCTGCGGCAGCCTCCAGGAACCGGTCTGTGCACTCTGCCTGGAACCGCTGCCAGGCGCCGGCGAAACCGCCAAACTGTGCGACAAATGCTGCCGCAAGCACAATCTGAATGGCAAGCGGCACAAGGAACCGGTCACCACCCTGGTGGTGGCGCCGAGCACAAAGACAAATAGCAGCACGGCTGCATATTTGGAGCACCGCTGCAATCTGTGCAAGCTGATACTGCCGCACGCCCAGAAGCTGCAGGAGCACCTGGTCGAGCACACGTTCGCCGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCGGCGGTGTTCACAGCGCCCGCCGGCCTCCTCAGCCACATGGGGGAGCACGGGGCGCGGCCCTACGACTGCAATCTGTGCACCGAGAAGTTCTACTTTCGGGCCGAGCTGGAGCACCATCAGCGGGCGCACGAGCTGCGACAACAGACGACCAAACAGGAGACTGAGATCAGCTCGGCGGCCAGTTCACCGAGGACGCCGACGAGTCCGCTGCACGCGGTTAAACAGGAGCTGTACGAATCGGAGCCGGGCACATCGCCCAGCGCAGAACCGGGCGCAGGGGACGAGGAGGAGTACATCGAGGTGGAGCAAGTGCCACAGGAGACACAACGAGCGGGCGAGCTGCTCAGCGCcgaacgcagcagcagcagcgcctaa
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSMPQLAAQGDESTAETKANGETVSATEEQQQQLQQEPIRPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLLTGTGSGGAGQPGHNAAGAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALATDSSPSRLEFPKRSRAQLAAATPTPTPLLRCSYCPKVTEFTSLEQLNAHLQSVHEQQQQQQSPPGDGDGSNVEQATNGFQLSCEYCTMKFVNIAALFQHMRGTHLDRLSSPNSYYEHFNRLATAGTFSPRLALEMPKQIKQDADAKLEQQELPTDLSSNKRRPLTPQSTSASASVPAPAPPGVFLCNQCNAGLPDFESFRNHLKSHIVEGMQLSCPHCGLNLPEQSEYERHVVAHFLISSSEFNCSASCGKSYSKAEELQQHLLSEHVQQLLKCVLCSELCENRMSMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGQQQQRERERDQQQQQLSGGGPSSNPLQCMFCRVVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGGGGAIKGAKETGAAAASMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGNATPTNQQAKFYSPLQVDTKATQPAPHPALMYGLSQRYLMEMYAAKANSPATSAAELPPQATPIVAGASGGAAATNYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGHQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSSPGCGSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRHKEPVTTLVVAPSTKTNSSTAAYLEHRCNLCKLILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLSHMGEHGARPYDCNLCTEKFYFRAELEHHQRAHELRQQTTKQETEISSAASSPRTPTSPLHAVKQELYESEPGTSPSAEPGAGDEEEYIEVEQVPQETQRAGELLSAERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00541932;
80% Identity: -