Basic Information

Insect: Drosophila paramelanica
Gene Symbol: -
Assembly: GCA_035043915.1
Location: JAWNMO010000674.1:6599136-6601232[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 3.4e-06 0.00021 21.5 0.8 3 23 208 229 207 229 0.96

2 6 2.4e-05 0.0015 18.8 1.8 1 23 237 260 237 260 0.95

3 6 7.9e-05 0.0049 17.2 0.3 1 23 266 288 266 288 0.97

4 6 2e-06 0.00012 22.2 0.5 1 23 297 319 297 319 0.97

5 6 9.5e-05 0.0059 16.9 7.5 1 23 328 350 328 350 0.98

6 6 2.9e-05 0.0018 18.5 0.7 1 23 356 379 356 379 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	3.4e-06	0.00021	21.5	0.8	3	23	208	229	207	229	0.96
2	6	2.4e-05	0.0015	18.8	1.8	1	23	237	260	237	260	0.95
3	6	7.9e-05	0.0049	17.2	0.3	1	23	266	288	266	288	0.97
4	6	2e-06	0.00012	22.2	0.5	1	23	297	319	297	319	0.97
5	6	9.5e-05	0.0059	16.9	7.5	1	23	328	350	328	350	0.98
6	6	2.9e-05	0.0018	18.5	0.7	1	23	356	379	356	379	0.96

Sequence Information

Coding Sequence: atgttcCCGCTGCTGAATCATTCAGTGTTCGTTGTTTGTCGCTGCTGTCTGGTGGAGCAGCCGCCGCTTTGCCACAGCATCCGCGACAACAATCAAATCAGCCTGGAGCTGTTGGCCCTGTCGCCCAATCTGCAAATCGTGCCCAGCGATGTCATCTGCCAGCTGTGCCTGCACCGGCTTCACGACGCCCTCGAGTTCCGGCAGCGCTGCGAGGAAGCCGAGCTAATCCTGCGCGCCAGGCACGAGCAGGCGCTGGACGATGCCCTCGAGTGCCTCGAACGGGAAGTGGGCTGCCTGGAGCAGGCCAAATCCACTGCGATGACAACGCCGCTGGAACCCGTCGACTTCGGCAACTTGGATCTATCCGATTTATTTCGGGGCAATTCCGAGCAGCCAAACACGACGGTTGCCAATTGGGATGCTGGCATCCTAAACACGCCCGTCCATTTGCCGGCAACGTTGGAGCCGTTGGAGGCAGAGGCAAGCGCGgaaccgcaacagcagcagcagacggaAAGCGCTGCTGAGATGCCAGCGCCCATCGAGAAGCCCAAGCGGAAGCAAGCTGGgcgcaaagcagcagcaagtggaGCGGGTCGAGCGCCAAAATCGCTGCGTCCGTGCACCGAGTGTGAGAAGAAGTTTACGCGTAACTTTCAGTTGAAGTTGCACATGATATCGGTGCACGGTTTGGGCGATGGTCTGCGGTACGAGTGCGAGGTGTGCTCAAAGAGTTTCGCGTCGCGTCACAGCCTCCGCTATCATGTCACATCGCTGCATTCGACAGACCGGCCATTCGCCTGCGAGCTGTGCGATCGTCGATTTGTGCTGCGCACCCAACTGATCTCGCACGCCCGGATGCACACGGGCGAAACAAAGCCGCGCATCTTTGACTGCAGCGTCTGCGGTAAAACGTGGCCCACGAAATCGGATCTGCGCACCCATATGCGCTCACACGATCCGGACATGTCCAAGCGACCCTATAAATGTGATAAGTGCCACAAGGCGTTCTTCACCCGCGGCCACCTCAACTCCCACCATTTGGTCCACACCGGAGAGAAGCCCTACGCCTGCACCTATTGCGACAAGTCGTACCAGAGTGTCGGCAATCTGAACAATCACACCTTGCGACAGCATTCGAATATCATCGAAACGCAGCAGATGAATCTCAATTATACAGACTCGTTGGATATTGAGAGTTAG
Protein Sequence: MFPLLNHSVFVVCRCCLVEQPPLCHSIRDNNQISLELLALSPNLQIVPSDVICQLCLHRLHDALEFRQRCEEAELILRARHEQALDDALECLEREVGCLEQAKSTAMTTPLEPVDFGNLDLSDLFRGNSEQPNTTVANWDAGILNTPVHLPATLEPLEAEASAEPQQQQQTESAAEMPAPIEKPKRKQAGRKAAASGAGRAPKSLRPCTECEKKFTRNFQLKLHMISVHGLGDGLRYECEVCSKSFASRHSLRYHVTSLHSTDRPFACELCDRRFVLRTQLISHARMHTGETKPRIFDCSVCGKTWPTKSDLRTHMRSHDPDMSKRPYKCDKCHKAFFTRGHLNSHHLVHTGEKPYACTYCDKSYQSVGNLNNHTLRQHSNIIETQQMNLNYTDSLDIES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00530424;
90% Identity: iTF_00561218;
80% Identity: -