Basic Information

Insect: Drosophila paramelanica
Gene Symbol: ham
Assembly: GCA_035043915.1
Location: JAWNMO010000617.1:9142812-9163494[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.59 36 5.0 0.0 2 21 363 382 362 385 0.87

2 9 0.039 2.4 8.7 0.7 1 23 392 415 392 415 0.91

3 9 5.3e-08 3.3e-06 27.2 0.5 1 23 421 444 421 444 0.96

4 9 3.5e-07 2.2e-05 24.6 1.5 1 23 450 472 450 472 0.97

5 9 8.9e-05 0.0055 17.0 3.8 1 23 478 500 478 500 0.97

6 9 0.0019 0.12 12.8 2.0 2 21 508 527 507 528 0.94

7 9 1.4e-09 8.8e-08 32.1 1.2 1 23 1006 1028 1006 1028 0.99

8 9 2.5e-07 1.6e-05 25.0 1.1 1 23 1034 1057 1034 1057 0.97

9 9 4.6e-05 0.0029 17.9 6.8 1 23 1063 1085 1063 1085 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.59	36	5.0	0.0	2	21	363	382	362	385	0.87
2	9	0.039	2.4	8.7	0.7	1	23	392	415	392	415	0.91
3	9	5.3e-08	3.3e-06	27.2	0.5	1	23	421	444	421	444	0.96
4	9	3.5e-07	2.2e-05	24.6	1.5	1	23	450	472	450	472	0.97
5	9	8.9e-05	0.0055	17.0	3.8	1	23	478	500	478	500	0.97
6	9	0.0019	0.12	12.8	2.0	2	21	508	527	507	528	0.94
7	9	1.4e-09	8.8e-08	32.1	1.2	1	23	1006	1028	1006	1028	0.99
8	9	2.5e-07	1.6e-05	25.0	1.1	1	23	1034	1057	1034	1057	0.97
9	9	4.6e-05	0.0029	17.9	6.8	1	23	1063	1085	1063	1085	0.98

Sequence Information

Coding Sequence: atgagcGGTAACAATTCGCTGTTGGGTGTGAAGAAGACGCCGGTATTCGAACCGCAGCTGAAGATGGGCTCTAACGGCGACGACTACGATCCGAGCGTCGtgcgccatcatcatcatcatcaccatcatttGGATCTCAGCACTGGGACGTCGGCGTTTGGTCCTTTGCCGGCGGCGCATTTAACGGCCAGCCAGGCCAGGGTCGAGGACTCGTTCGCCCGCCACCTGCCGCCCACGATAAGCCCGCCGCCAGTTACGctgcaccaacagcagcagcagcatcaacagcagcaactgcagccgttgcagttgcagcaacagcagctgctgcgttcTCCGCCCGCCTCCACATCTGCCTCGGCCTGCAGCAACGGATCCGGTTCCGGAGCCGGTTCCGGCGCCAACATGCAGCAACTGCTCAATGACAAGGCCCAAGCGGAACGCATCCTGCTGGAGATGGCGCGCCTGCGCGAACCCGTCTGTGATCTGGATATACGTGATACCGGCGTCTACGCCAAGACACATCTGCCCCGCGGCACCCGCTACGGCCCCTTCCCCATGCGCCTCTGCCAGCAGCCCAGCGATCGCCATTTGGCCTGGGAGGTAATTGCGGGTCCGCTGTTTCACGGCTGGCTGGAGCCCTCGGCAGATGTGGCCACATGGCTGAAAAAAATCCGCACCGCGCCGAGCGACGAAATCGAAGAGGCTAATTTAAGGAATTTCATTATCGCCGGCTATctgtGGTACGAGACAAAATGCGACGTAAATGCTGGCGCTGAAATTGTCGTCGATCGGCGCTCGCAAACGCCGCACGATATTAGCGATAGTTTCATGAACGGCAGCGCTGCGggcgcggcggcggcaacagcgatggcagcggcggccaccgtccacagcagcagcagcagcagcaaaagcaattgcaacagcagcagcaacaacaacaacaacagcagcttaTTGCCCGGCGATGATCGCAGCGATCGTGATAACGGCTTTTATAGCGGCGACGAATTTTCCAAAGAGAAGAAAAACTCATCGCTGACGGAAAACGATTTCACAGACGACGAAAACGGTTTCGATATACGTTGTGAGGTCTGTGATAATGTTTATACGGACTTAGAACGACTGGATGATCATCTGGTGGGCGCGCATCATTTCAAGCGCGGAGAATTCGCCTGCGAGCTTTGTGCCCAACGCTTCTGCCATCGTCCTTTGCTGATCAAACACGGCGCGATCGCCCATAATAATATACGGAATTATTCCTGCGAGAACTGTTCCAAGgTATTCCGTGACCCATCGAATTTACAGCGGCATATTCGCGCCTATCACGTCGGCGCTCGCAGTCACCCCTGTCCGGAGTGCGGTAAAACGTTCGCCACCTCGTCGGGACTGAAGCAGCACCAGCACATCCACTCCTCGGTGAAGCCGTTCGCCTGCGAGGTCTGCTTCAAGGCGTACACGCAGTTCTCCAATCTGTGCCGCCACAAGCGGATGCACGCCGACTGCCGCATGCAGATCAAGTGCAAGAAGTGCAACACCAGCTTCAGCACGGTCACCTCCCTCTCCAAGCACAAGAAGTTCTGCGACAGCTCCGACAGTTTTCGCGGCCGCCTCCAGGATCTTCATTCGCATTCGCAGCgcgaacagcagcatcagcatcagcagcagcatcagcatccgcagcagtcgcagcacgGACCGCCGTCGCATCCGCCGCCACTTTTGTTGCCGCCCGGCGCTCATCAGCGTttagccgccgccgccgccgttgccgccaGCAGTGAGGCGGGCAGCACTGCGatggccacgccccccaaTCACCTGTTCATGATGCGGTCGACGCCCTCGTTCTTCGCCAGCTTCCCGCACTACGGCCTGCCCAACTTCTTTGCGCCCGGCCTGCAGCAGGCGGCCAATTTCCAGCTGCCGCACATATTCCCGAATTCGCCGCAGCTTCTGGGCGACATGGGACGCGGCCTGGCGCCGCTCGTCTCCCCGAACGCCGccttccagcagcagctgatgagCCTCAAGGCGGACTCGCCGCATCTCAAACGCGAGCCCAGCCCGCCGGAACGCAAGCCCATCAAATCGGAGCTGGACGAGGAGGAGTCCAATTCGATGGCCTACGATGAACTCAAGCCAAAGCTGGAGTCCAACAAGCTGCCCAAGCTGAAGCCAGAGTCCGGCAAGGTGAAGCACGAGGCCAGCTGTTCCCAGCCGGCCGAGGATGACAACGACAATGATAACGATAGGaAATCCATAGATATAATCAGCACGCCGCCGCCAGCGGACACCGAGCTGGACATAGATCAGGACAAGGGCAACGTTGAGCTGCCGCTGGACTTGTCGATCAGTCGGAAACGCTGCAGTCCGACGCCCGCCTCGCTCTCCATAGCGCTGTCCAGTCGCACTTCGACGCCCGAACcggacgaggaggaggatgacgacgaggaggaggaggaggaggagcggCCGCCGCCGGCCAAGCTGCCGAAGCGCCACAGCTCCGGCGAATCGTCCAACTCGCGCCAGTCGACGCCCATCGCCAGCGTCAGCGCCTCGCCGGGCCTGACGCCCTCCCCCTCGCCGCCCATCAGCACCGGCGGCGAGCTGAGCAGCATGTCCGAGAGCGCTGCTGCCGCGGCGGCAaatgctgcggcggcggcggcggcagcggccgcaACAGCGATGGCCTGTCCGCGGCCGCAGCTGcatccgcagcagctgctggaggaGCTGTATCGGACGCGTTTTTCACAGGCACCGTTTCATTTTTTAGGCCGAATGGGCGGACGGCCAGGTTTTGAGGCACATAAGTCGCCAGCTGCGTGCGCTCCTGCGCCGATCAGCAGCTCGCGTCATCTGCCGTTTCCGCCCGAGCACAACTTCCGCGAGGCGCTGCGCGCCGCTGGCCTCGCCACAGGCCGGCCCATGGCCGCCGGCGCCGCCTGCACCAGCCACGGCCACGGTCATGGCCACGGCCATGCCAGTGGCAAGCTAAAGGACCGCTACACCTGCAAATACTGCGGCAAGGTGTTCCCGCGGTCCGCCAATCTGACGCGTCACCTGCGCACGCACACCGGCGAGCAGCCGTACAAGTGCAAGTACTGCGATCGGGCGTTCAGCATCTCCTCGAATCTGCAGCGGCACGTGCGCAACATCCACAACAAGGAGCGGCCGTTTCGGTGTCACATGTGCGATCGCTGCTTTGGCCAGCAGACGAATCTCGATCGCCACTTAAAGAAGCACGAGGCGGACGCCGGCGGCTTTGAGTACAACGATTCGCCCAGCTCGAACGAGGCGAACGATCGCGACGAGGCCAACTTCGACGACATCCGATCGTTCATGAAGGGCGTCTACACGCCCACCAGCCATTGCGGGGCCGATGGGGATACCGAGGAGTATGCGGGCAGCGATGATCAGTTGTCCGTGTCCACGCGCGAATCGGTCAGCTTTGACAAGGAGCTGCTGTCgaatggcaacaataacaacaacaacaacaataacaataacaacagcaatagcagcagcaacaacaacaacaacaacaacaatcaggcGGCACTGGGCAAAACAATTGCCGTTAGCACATAA
Protein Sequence: MSGNNSLLGVKKTPVFEPQLKMGSNGDDYDPSVVRHHHHHHHHLDLSTGTSAFGPLPAAHLTASQARVEDSFARHLPPTISPPPVTLHQQQQQHQQQQLQPLQLQQQQLLRSPPASTSASACSNGSGSGAGSGANMQQLLNDKAQAERILLEMARLREPVCDLDIRDTGVYAKTHLPRGTRYGPFPMRLCQQPSDRHLAWEVIAGPLFHGWLEPSADVATWLKKIRTAPSDEIEEANLRNFIIAGYLWYETKCDVNAGAEIVVDRRSQTPHDISDSFMNGSAAGAAAATAMAAAATVHSSSSSSKSNCNSSSNNNNNSSLLPGDDRSDRDNGFYSGDEFSKEKKNSSLTENDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFACELCAQRFCHRPLLIKHGAIAHNNIRNYSCENCSKVFRDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCKKCNTSFSTVTSLSKHKKFCDSSDSFRGRLQDLHSHSQREQQHQHQQQHQHPQQSQHGPPSHPPPLLLPPGAHQRLAAAAAVAASSEAGSTAMATPPNHLFMMRSTPSFFASFPHYGLPNFFAPGLQQAANFQLPHIFPNSPQLLGDMGRGLAPLVSPNAAFQQQLMSLKADSPHLKREPSPPERKPIKSELDEEESNSMAYDELKPKLESNKLPKLKPESGKVKHEASCSQPAEDDNDNDNDRKSIDIISTPPPADTELDIDQDKGNVELPLDLSISRKRCSPTPASLSIALSSRTSTPEPDEEEDDDEEEEEEERPPPAKLPKRHSSGESSNSRQSTPIASVSASPGLTPSPSPPISTGGELSSMSESAAAAAANAAAAAAAAAATAMACPRPQLHPQQLLEELYRTRFSQAPFHFLGRMGGRPGFEAHKSPAACAPAPISSSRHLPFPPEHNFREALRAAGLATGRPMAAGAACTSHGHGHGHGHASGKLKDRYTCKYCGKVFPRSANLTRHLRTHTGEQPYKCKYCDRAFSISSNLQRHVRNIHNKERPFRCHMCDRCFGQQTNLDRHLKKHEADAGGFEYNDSPSSNEANDRDEANFDDIRSFMKGVYTPTSHCGADGDTEEYAGSDDQLSVSTRESVSFDKELLSNGNNNNNNNNNNNNSNSSSNNNNNNNNQAALGKTIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00547517;
90% Identity: iTF_00561178;
80% Identity: -