Dpar008013.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila paramelanica
Gene Symbol
-
Assembly
GCA_035043915.1
Location
JAWNMO010000559.1:532618-536041[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0076 0.47 10.9 0.6 2 23 143 165 142 165 0.90
2 12 4.7e-06 0.00029 21.0 2.9 2 23 179 201 178 201 0.96
3 12 0.21 13 6.4 8.8 2 23 481 502 481 502 0.97
4 12 1.3e-06 7.7e-05 22.8 2.8 1 23 508 531 508 531 0.96
5 12 0.00057 0.035 14.5 0.7 1 23 536 559 536 559 0.96
6 12 6.5e-05 0.004 17.4 5.5 1 23 577 599 577 599 0.96
7 12 0.0001 0.0062 16.8 1.2 1 23 604 626 604 626 0.98
8 12 3.4e-05 0.0021 18.3 1.7 1 23 632 654 632 654 0.95
9 12 1.6e-06 0.0001 22.5 0.8 1 23 660 682 660 682 0.98
10 12 3.5e-07 2.2e-05 24.6 2.7 3 23 690 710 689 710 0.99
11 12 7.8e-08 4.8e-06 26.6 1.7 1 23 716 738 716 738 0.99
12 12 1.6 99 3.6 5.2 1 19 743 761 743 766 0.88

Sequence Information

Coding Sequence
ATGCCTGACAGCTGCGGTCAGTTTGATGCGGAGCGCGTCTGTCGCGTTTGCCTACGCGAGGTGGGCGATTTCTACTTCATCTACGATGAGGCGCCTGTGGAGCAGGGCGCAAACATTGCCCAGATACTTAACGAGTGTACGCGGTACACCTGCGAGCGTTACGACAAGTTGCCGCACCACATGTGCGACACCTGTATCAAGGCCGCCTGCCAGGCGTATCGCTTCAAGCTGGACGCGGAGAAGGCCTATCGCTCGCTGGTGGCCATCCTGGGGTGCACACCCGTCACCACGCCAAACAGCAGCGAGGTGTGCACCCAAACAGAGCAGGTAGCGATGCTGCCGTGCGACATCTGCAACGATCAATTTCTCAACATTCTTGAGTTGCGACTGCATCGCAATCGCCAGCACAAGCACATGGAGCAGCTCAAGTGCAAGCTGTGCGATGAGCAGTTCCAGCAAATACGCCAGCTGCGCAACCATCTCGTGGAGCAGCACGGTCAACAGGCGGCAGCGTCGTTGCTGCACCGGCGTCTGGAGTGTCGCCTCTGCCAGCGCTCCTTTGTCCGGCGCGATCATATGCAGCGCCATATGCGCACCGTCCACAATGCTGACGACGGAGATCGGTTGGTCCGGTCACCGGCCGAGCAGCAGTTAGTTCAGTCTGAAGTGGACTGGCCGCCCATCGACGAAGCGACCATGCACAGCGGCGACGAACTGGAATCGGCTGCCATTATATTCAATGAGGCGGCTGCTTGTACCGACGACGATGAGAACGTTAACTGCGAGAGCGGCTATCAATACCATACAACGAATCCCATATCAAGCAATGAAGAAGCTGACGACGAAGACGTCCATGCCGAGGCTAAACAATCGCTCTGGCTACACATTAAGCCAGAACCTGAAGCGGAAACGGATCCGGAGCAATGCCCGACGCAATTACATCGCGAGAAGCGCAGGAAAAAAGCAAATCTAAAACCTGTAACACACACTGGGACGGAGGACGAGCATGAGAGTGAAGACACGCGGAAAACCACGTCCACTGTTTTGAATGCGGAGGTCAAAGAGGAGCCTCTGCTCACCGGCGGCGATCTACAATTGTCTATAAAGGAGGAGCGACAGCGCGTCGACAGCATTAAAGAGGATGAGGACGAAATGGAGGCGCCAATAGCTAACGTTTCACAAAGTGCAGACGACGATGAAGATGGGGAAGAATTTGGCAATGCGGAGAGCGACATTTTTcaggatgacgatgatgatgacgacgacgatgacaaTGAAGAGGAAGACGAAGCGGATGCAGATGTGGAGGCATATTCCGAGGATAAAGCCCAGGGGACTAAGGTGGAAATCGTGCGCGAGTATCTGGAGAAGCCAACACCTGGCAAACAGCGACGTCGTCGACGCAAAAAACCAAACGATTCGCAGCCGAATCCGGAGAACCGCTGCGACATCTGCATGCGCACCTTTTCCCGCCATTGCCACTTGTTGCGGCACAAACTGTCGCATTTGGAAAAGAAGCCGCACAGCTGTCCGCACTGCCCGAAGGCGTTCGCCCGCAGCGATCATTTAAAGGCGCACGTCCAGAGCCTGCACGGCAACAAGGAGCACAAATGTGTGCTGTGCGAGGCAGCGTTTTCCCGCCTCGACGCCCTCGAGCGCCACAAGATGAGCAAGCATAACGGCGAGGGCCTGGACGCCAGCAGTGAACTGAAGCTGCAGATGAGCGAGCACACGTGCGAGTACTGCTCGAAGCGGTTCTCCAGCAAGACGTACCTGCGCAAGCACACGCTGCTCCACACCGAATTCCTGTACGCGTGCAAGAGCTGCGACGAGACATTCAAGGAGCGCCAGGAGTTGCGCAACCACGAGAAGACGCACACCGGACAGCGAAATTTCCTCTGTTGCATCTGCGGCGACAGTTTTGCGCGCAACGATTATCTGCGCGTCCATATGCGGCGGCACAACGGCGAAAAGCCATACAAGTGCCGTTACTGCGACAAGGCATTTCCACGCGCTACAGATCTCAAGGTACATGAGCGCTATCACACGGGCACAAAGCCCAATCTGTGCAATACGTGCGGCAAGAGCTTCCATCGCGCCTACAATCTGACCATACATATGCGCACCCATACGGGCGAGCGTCCCTACAAGTGCGATCAGTGCTCCAAGAGCTTCAGCCAGAGTAACGACCTGAAGGCGCACATTCGCCGCCACACGGGTGAGCGCTACAAGTGTCCGCACTGCGATGCCTATTTCCTGCAGCTTTACCATATGCGCAACCATTGCCTCAGTGCCCACAACAAGCACATTGAGACTAAAACGGGTCGCCTGCAGCGCACCGGCCTGCTGGACGAGCCGAATCATGCGCATCTGACCACTGTGCTAATGCCACCGACTCGTTTTCAACAGCAATCAACGCCGGATCCGCAAACACAGCTGCCGGCAACGTCGGCGCAGCCAATTGCAACACCAATTCTGCATTCGCCGGTCACGTACAGTACAACGTCGCCAGTGTCCGTGTCCGTTCAAGTGCCGGATGCTGCCGGATTTGTGGGTGCGGCAAATAGCGCAACAGCTACCGCGACAGCGCCCTTTGGGGCATTTAATATAGCGCCCGTGGTGATGGCGCATCTCATGTACAATCATGGCGGCAACAGCCAACAGAGCAACGCCAGCGGCAGCGAGGCGGGAAAATAG
Protein Sequence
MPDSCGQFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERYDKLPHHMCDTCIKAACQAYRFKLDAEKAYRSLVAILGCTPVTTPNSSEVCTQTEQVAMLPCDICNDQFLNILELRLHRNRQHKHMEQLKCKLCDEQFQQIRQLRNHLVEQHGQQAAASLLHRRLECRLCQRSFVRRDHMQRHMRTVHNADDGDRLVRSPAEQQLVQSEVDWPPIDEATMHSGDELESAAIIFNEAAACTDDDENVNCESGYQYHTTNPISSNEEADDEDVHAEAKQSLWLHIKPEPEAETDPEQCPTQLHREKRRKKANLKPVTHTGTEDEHESEDTRKTTSTVLNAEVKEEPLLTGGDLQLSIKEERQRVDSIKEDEDEMEAPIANVSQSADDDEDGEEFGNAESDIFQDDDDDDDDDDNEEEDEADADVEAYSEDKAQGTKVEIVREYLEKPTPGKQRRRRRKKPNDSQPNPENRCDICMRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCEAAFSRLDALERHKMSKHNGEGLDASSELKLQMSEHTCEYCSKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQELRNHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCDKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCSKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEPNHAHLTTVLMPPTRFQQQSTPDPQTQLPATSAQPIATPILHSPVTYSTTSPVSVSVQVPDAAGFVGAANSATATATAPFGAFNIAPVVMAHLMYNHGGNSQQSNASGSEAGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00547491;
90% Identity
iTF_00547491;
80% Identity
-