Basic Information

Insect: Drosophila paracracens
Gene Symbol: PRDM1
Assembly: GCA_035044025.1
Location: JAWNMN010000192.1:7597853-7602430[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3.2e-05 0.0021 18.4 2.5 1 23 937 959 937 959 0.99

2 5 9.4e-06 0.00062 20.0 5.1 1 23 965 987 965 987 0.98

3 5 2e-06 0.00013 22.2 4.3 1 23 993 1015 993 1015 0.98

4 5 0.00066 0.043 14.2 2.4 1 23 1021 1043 1021 1043 0.97

5 5 0.00011 0.0073 16.7 0.1 1 22 1049 1070 1049 1070 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3.2e-05	0.0021	18.4	2.5	1	23	937	959	937	959	0.99
2	5	9.4e-06	0.00062	20.0	5.1	1	23	965	987	965	987	0.98
3	5	2e-06	0.00013	22.2	4.3	1	23	993	1015	993	1015	0.98
4	5	0.00066	0.043	14.2	2.4	1	23	1021	1043	1021	1043	0.97
5	5	0.00011	0.0073	16.7	0.1	1	22	1049	1070	1049	1070	0.96

Sequence Information

Coding Sequence: ATGCAtggacatcatcatcatcatcagcagcagcaacagcagcaacagcagcagcagcagcagcaacctttgcagccgcagcaacaagtgcaacaaatgcCAGTCGCAatgaagcaacagcagctgcaacaacagcaacaacaaacacaacacatagccatacagcaacagcaccagcagcagcatcagcagcagcaaacgcatccacatcatcatcatcatgcaACAGCACAGCATCCCCAACGGCATCCACAACAGCATCCACAACAGCATCCACATGCGCATCCACATCATCATTCAAAGCTGCTGCGTCGCTcgcgcagtcgcagtcgcagtccgACGCCGGATGGGACACAGGACTACGATGTGACGCGGATGCGCGAGGAGGACTTTGAGCGTCTAGCGGTATATCTGGTGCCCGATGTGCAAGCGGAGCGAGGGTTGCCAAATCGTGCGGATAAAACGCTGCCGCGCAGCCTAACGCTTAAGTCCTCCATGGTTTATTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGCGTTATACCGCGTGGCACACGCTTTGGCCCATTCGAAGGCATTCCAACCTCAAATTACCCAAACGATAAGAATAAGGCGCGATATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGATTATTAAGATCTTCAAGGATGATGATTATTACTATCTGGATGGCTCGGATCGCTCGGAATCCAATTGGATGCGCTATGTTGCCTCGGCGTATAGTTTGTCCGTTATGAATTTAGTGGCATGCCAGCATCAGGATAACATCTATTTCTACACCACCCGCGACATATTGCCCAACGAGGAGCTGATGGTCTGGTACTGCAAGGACTTTGCCAGCCGCCTGGGCTACGATGTGGACCCGGAGCGCACCATTTTCGGTGCCTGCAAAcaggatgtggatgtggacgaggatgaggacgatgaACTGCCGCACAAGAAACCGCACTATGCAATGCCCGCTCCCGAAATACCCGCCGAGGTAGCTGTCAGTCACATTACCTATGTAATGGGATTGCATTTGCCCGGTgcaccacctccaccaccaccacccgcAGGATCAGTTGGAACAGCTGGTGCTCcaccaacagcaccagcacaaGCATCCGCCCAATGCTGTCGTCGCGGCAGTCCACCTGCCCATGTCAGCACcacaaccagcagcaacaccagcaccaaTTCTCTTCATCCGCATATACAGCACAGTCGTCATGCCTCGGTAATCATTGGCCAGGATCGGTCTCCCCTAAATAGCAGCTGTGAGAAGGAGACAGCTGGTTCACCGCTCTGTGGCAAGGATGCTCACTATGAGCATCAGTTGACGCCGCAGGATGGCAGCGTGCGATCGGTGCGCTCCGATGAGGGTTACCACAGCAACGAGTGCCAGGAGGATGGACTGACGCCCCCAGAGGATTCCAGTGATAGCGAAAGTGAGCATAACTATGTGCTCGACTGCTCCAAGAAGGCAATTGCACCCAAGGAGACGGTCATTGCGCAGGCACAAAAGCCGAGCAGTGTGTCATCACCACCAGCAGTAgccaacaatagcaacagcaccaccagcaatAGCATccccaacagcagcgccaccaTCACGCCCACCGCTGCCATTGTCACGCCCAGTTGTGAGGCGGACAAGAACGAGTATCGTAAGTTCAAGGTGAAAATGCCACTGAAATACGAGTTCAAGAACAAGAGTTGTGTGAAAACGGAACCACTCAAAGAAGTGGATGAGCAACTGCCGCCAGTTGGTGTCGGtctggaggaggaggatctACATGACTTGCATGGTGCAGCGACGACGCATTGCGAGGATTCGTTGTGCCCGCCCAGCACGACAACAACGCTGGGTGAGGAGCACCATCAGCTGCAGCACGTGGTGGAGCCAACGAATCCACAGCCAGCCTCCTCCACAGTGATTGTGCTGGAGCACAGCTCCAATGGACAGACGCGAACCATTGTGCCGTTGAGTAAGCCCTACTACGAGGCCGATCCGCCCGTGGAGCGCTATGTGCGCTTCACACAGCCCAGCTCCAGCATCTTGGAGACGATACTCACTAGCCAGCATCGTTTGGaggcagctgccgccgcagcaAATGCCTGTAGGCAGGCAAATGCTGCAACACCACCGCCCACATCGCCCACAGAGATGGCCTACAGCTATAAGAAATCGCAGCGCTATGGCAATGCAGTAAGTCCCGATTCCAGCTCTAATCTGGGACAGCCGCAGGAGATTGCTAGTGCGCATGTGGTGCAGGAGCAGGAACTGAGTCTGAGTCGTGGTGCATTGATCAAAGGCGAATGTTCGCCACCGCCTCCATCCtcgcatcatcatcacaatGTGATCTATTCGCCGACGAGGACGCATCACGGTGGCTACGAACCGGGCAGCCATTCGCCCAGCTATGCCGGTTATGCGGGCTACCCAGGGGCACAATCACTGCATGCGGCAACGTCAACGTTCCACTCACCACCCCACAGTTCGCATTCCCCCTTCGATCGCCAGTCGAATGCCTCTAGTGGCGGTGGCTCCGCTTCCAACTTGCATCTGCTGCAGAGCAGCACACAAATGTTGAATCATCCGTTGATGCAACCGTTGACGCCGTTGCAGCGTCTATCTCCGCTGCGCATCTCCCCACCCAGCAGTCTCAGTCCCGATGGCAACTCCTGTCCACGCAGCGGCAGCCCTTTGAGTCCCAACTCGTTGGCCTCTCGCGGCTATCGCTCGCTACCGTATCCCCTAAAGAAGAAGGATGGGAAAATGCATTACGAGTGCAATGTGTGCTGCAAGACATTCGGCCAGCTGAGCAATCTCAAGGTGCATCTGCGCACCCACTCCGGTGAGCGTCCGTTCAAGTGCAATGTGTGCACGAAGAGCTTCACACAGCTGGCGCATCTGCAGAAGCATCATCTGGTGCATACGGGTGAGAAGCCGCATCAGTGCGATATCTGCAAGAAGCGTTTCTCCAGCACATCCAATCTGAAGACGCATCTCCGGCTACACAGCGGCCAGAAGCCCTACGCCTGCGATCTCTGTCCACAGAAATTTACACAATTCGTGCATTTGAAGCTGCACAAGCGCCTGCATACGAATGATCGACCGTATGTGTGCCAGGGCTGCGATAAGAAGTATATTAGTGCGTCTGGACTGCGCACGCATTGGAAGACGACCAGCTGCAAGCCCAACAATCTAGAGGAGGAACTGgccatggcagcagcagcgacctCCGAGTGTTTGGACAAGGATCTACCGGAGCCGGATTCGCGTGAGGCATATGAGCAGCTGCACCAGCACATGCATCCCGTGCATCCGAGTTTGCGTCATTTAGCTGGCACACAATCGCCGCCTCGTCTCATTCCGCTAGGCAGCAATGGGCAGCCGCATATGCATATGCGACAGCATTCACATCCGGCGCCGCCAGGACATTTAATGCACTCGCCACATGGTGGTCCGCCCATGTTGCTGACCACAGCCAATCAGTTACCGCCACCAACAACGCCACAtcacatgcagcagcaacagcagcagcaacagcaacagcagcaacaaccttTGCCACAAGTCTCACCAggcagacagcaacagcagccacagcattTGGGTGCAGCTCATCATTTGGCGCAGCATTCGCCCAAGTCGCTGAAGCCTTTGCCGGACACTGGCTATATGCATGGGCCGCATGTCCAGGCGCAGGAGAATCGACCCTCGGTCATTGAGTCCTCCAGCCAGCCCATGATCATTGAGTGCACGTAG
Protein Sequence: MHGHHHHHQQQQQQQQQQQQQQPLQPQQQVQQMPVAMKQQQLQQQQQQTQHIAIQQQHQQQHQQQQTHPHHHHHATAQHPQRHPQQHPQQHPHAHPHHHSKLLRRSRSRSRSPTPDGTQDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGIIKIFKDDDYYYLDGSDRSESNWMRYVASAYSLSVMNLVACQHQDNIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQDVDVDEDEDDELPHKKPHYAMPAPEIPAEVAVSHITYVMGLHLPGAPPPPPPPAGSVGTAGAPPTAPAQASAQCCRRGSPPAHVSTTTSSNTSTNSLHPHIQHSRHASVIIGQDRSPLNSSCEKETAGSPLCGKDAHYEHQLTPQDGSVRSVRSDEGYHSNECQEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSVSSPPAVANNSNSTTSNSIPNSSATITPTAAIVTPSCEADKNEYRKFKVKMPLKYEFKNKSCVKTEPLKEVDEQLPPVGVGLEEEDLHDLHGAATTHCEDSLCPPSTTTTLGEEHHQLQHVVEPTNPQPASSTVIVLEHSSNGQTRTIVPLSKPYYEADPPVERYVRFTQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQPQEIASAHVVQEQELSLSRGALIKGECSPPPPSSHHHHNVIYSPTRTHHGGYEPGSHSPSYAGYAGYPGAQSLHAATSTFHSPPHSSHSPFDRQSNASSGGGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPDSREAYEQLHQHMHPVHPSLRHLAGTQSPPRLIPLGSNGQPHMHMRQHSHPAPPGHLMHSPHGGPPMLLTTANQLPPPTTPHHMQQQQQQQQQQQQQPLPQVSPGRQQQQPQHLGAAHHLAQHSPKSLKPLPDTGYMHGPHVQAQENRPSVIESSSQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610151;
90% Identity: iTF_00498390;
80% Identity: -