Basic Information

Insect: Drosophila parabipectinata
Gene Symbol: Mtf1
Assembly: GCA_018153455.1
Location: JAECYA010000551.1:7267211-7278041[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00015 0.011 16.0 1.8 1 23 351 375 351 375 0.98

2 6 9.7e-05 0.0072 16.6 0.2 1 23 381 405 381 405 0.98

3 6 6.2e-05 0.0046 17.2 1.0 1 23 411 435 411 435 0.97

4 6 1.8e-07 1.4e-05 25.2 4.9 1 23 440 462 440 462 0.98

5 6 1e-06 7.7e-05 22.8 3.2 1 23 468 492 468 492 0.99

6 6 0.00012 0.0093 16.2 3.7 1 23 498 522 498 522 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00015	0.011	16.0	1.8	1	23	351	375	351	375	0.98
2	6	9.7e-05	0.0072	16.6	0.2	1	23	381	405	381	405	0.98
3	6	6.2e-05	0.0046	17.2	1.0	1	23	411	435	411	435	0.97
4	6	1.8e-07	1.4e-05	25.2	4.9	1	23	440	462	440	462	0.98
5	6	1e-06	7.7e-05	22.8	3.2	1	23	468	492	468	492	0.99
6	6	0.00012	0.0093	16.2	3.7	1	23	498	522	498	522	0.95

Sequence Information

Coding Sequence: ATGAACGAGCAGCAGCAACAACAACAACTGCCCATCGAGCAGCACTACTACCAGCGCAGCTGCCATACCAGCAATTCCTTATCAGATAGCCGGGATTACGATACGAACTCGTCGCGTACCTCGCTCTCTGGATCTCCGCCCGCCCCCTCTTCCGCCGGATCCATTTCCCTAGACTTTGATGGAGGGTTCGGAACGATGGGCGGTGGAGCCCTGTCTCAGCTACTTGTCCCGAAACTGGAGGCGGAGAGCGGCCTGGGTATCATCCACTCGGACAGCTACAGCCTCTACAGAGCACCAGGATCCATCGAATCCGCCAGCGGCGAGCAACAGGTGCTGGATCTCGGGCTAACGCTCGAGCAGGACGATGTCCAACTCTCAGAAGCCACCTACAATGCATTATTCAGCCACGAGAATCAGTCCAGCACATCCATCACACAATCCCTACAAAGTCACATACAGTCCAAGTCAGAGGAAGGGGGGGAGGATGAGGAAATGCACCAGCTCCTCACCCTACCCGCCACTCAACTAACACCCATGCCCATTACGGTCATACCCATCACATACCATCACACCGAGTCATTGACCCCCAGTTTGGGCGAGGTGCCCCTGATAGCCACACTGAGCGAGGACACTGGCCAGGTGCTCAACCTGGACGACATCTGTTTCACCCTGGAGTACCAGTTCGAGAACCAGAAACTCGTCCAGGTCCAGCCGCCCACCGTCGTTTCGCTGAGCATGCTGGCCCCAGCCTCCGAAGGGGTGTCTCCCATTCTACCCAACTGTGATAATGGCCAGGGAATCGTCAACGTCAACTCCAATAGCAACTCGATGGAGGCCACTTCTCCGGCGTATTTCACCGTCGAGACGAGCTATGTGGACGATTACGATCAGAATGAGCTGGACGAGGATGAGCAGCTGGCGCACTGCATCCAGCCGGGCGTCTTGCACAAAGATGACCAGGAGTATGAGGAGGACGAGGTCGGGCATCAGGATGAGAATGATCAGCTCATGGCACTGGCCTACGAGAGCTCCGACGAGGCTCTTAGTCGCTACAGATGCAACTACGAGAACTGTTACCGCAGCTACAGCACGATTGGAAATCTGCGAACGCATTTAAAGACACACACAGGCGATTACAGCTTCAAGTGCCCCGAGGATGGATGCAACAAAGCTTTCCTGACATCGTACAGCCTGAAGATCCACGTCCGTGTCCACACGAAGGTGAAGCCCTACGAATGCGAAGTGACTGGCTGCGATAAGGCCTTCAACACCCGATACAGATTGCACGCTCACCTGCGGCTACACAACGGGGAGACGTTCAACTGCGAGCTGTGCCAGAAGTGCTTCACCACCCTGAGCGACCTGAAGAAGCATATGCGAACCCACACCCAGGAGCGACCGTACAAGTGCCCGGAGGACGACTGCGGCAAGGCCTTTACTGCCTCGCATCATCTGAAGACGCACAGGAGGACGCACACCGGCGAGAAACCGTATCCCTGTCAGGAGGACAGTTGCCAGAAGTCGTTCAGCACATCACACAGCCTCAAGTCCCACAAAAAGACCCATCAGCGCCAGCTGACCAACAAGGGCCGGAAGAAGAGGCCTCTGAAGCCGCAGCAGGGGAAGCTCACGGACCTCGAGCAGGATCAGGAGAACCTTCAGGACCAAAGCCAGCTGGAGGAACAGGAAGAGGGAGAAGAGAGGTCGGAGATGATGGCCCTAAATCCAGGAAGTCAGTGCTCCGAGACCACCAGCACAGATAGTGGAGTGGTTCTGCACACTCTCACCGGGCAGGATCAGTTACAGAGCGTGTTTATCCTTCCGGAGGATCAGCCACTGACCCTACCCGAAACATCACAAGCCTATCAATTGTCCTACGCAGCTGAGGAGGAGATACCCAGTCCCTGGTCGGATGCGGGGGTGCTCCTTTCCAAGCCCATCATTCCCATGGCACCGGTTACAGATGCCTGTGTGGCTCTGCCCACGGAGATGCCCAGCTTCGTCGACTTGAAACCCACCTTTGGTAACGGTGTGAGCGGAAATATGGAACAGCCCCAAGCCGAGATCATGGAGGTGGAAACTGTGGCACCGCCACTACCAACTCCTACCCTGGAACTCAATCTACAGAACATTGAGGAGCTGCTGAAGCAGGACTCCAGCTTCGACAACGAGGAGGACATGGAAACCGATTCCCTGCTGAACGACATCCTCATGACCATCGACAACAACAGCGCCCTGCTGCAGGAAACCCTCCACCAGGCCTCTCAGGTGCCAACGGACGCTTCCGGCCTGGTGGAACTGGACATTCGGGACAATAAACCAACTCTGAAACAGATAACAGCCGATGCGGGCATCTGCAATTGCACCAACTGCAAGTGCGATCAGACCAAGAGCTGCCATGGCGGGGACTGTGGAGCATCCAGTCAGAAACCGACGAGGACCACCACCACGACCTTGGCCACTCCGAAGCCGAGTGGCGGGAAGCGGATCTGTGGCAGCAAAAAAGTGAGTAAACGCGAGGCGGAAATGAACCAGAACATCGAGGATGTTGCTTTGCTGCTGCAAAACCTGGCTTCCATGGGCAACGCCAGCTCCTCCGGCGGCGGTTGCTGTGGCGGTGGTGCGGCCAAGCCAGCCCCTACCACTGGCGGCTGCTGCGGAGAACCCAAGATTCAGCCCGAGCCGACCAAGAGTTGCGGCAGTTCCTCATCCGGTGGCGGCGGCTGTTGCGGTGGGGGAGGAGCACCTGCTGCACCACCATCGCAATCTTCGGGCGGCTGCTGCTCCAGTAACAAACCAGCGCCAGCACCAGCACCGACGCCGCCCTCCGCTTCAGGGTGCTGCTCGGGCAAGGCCAAGGCCCAGGAGCCACCGGTCATCACCAACGCCCCCGCAACCGCCGTCAAGGGGAGCTCCTGCACCTGCAAGAGTCCGGCGGAGGGGGTGGCCAACGGCTGTTGTGTGGTGATCTGCATTAAAACGCTGCAAGCGCTCCGCAAAGTTCTGACGCGCCGGAATCTGAACCTAATGCTTTGTCCACAACAGAACTAA
Protein Sequence: MNEQQQQQQLPIEQHYYQRSCHTSNSLSDSRDYDTNSSRTSLSGSPPAPSSAGSISLDFDGGFGTMGGGALSQLLVPKLEAESGLGIIHSDSYSLYRAPGSIESASGEQQVLDLGLTLEQDDVQLSEATYNALFSHENQSSTSITQSLQSHIQSKSEEGGEDEEMHQLLTLPATQLTPMPITVIPITYHHTESLTPSLGEVPLIATLSEDTGQVLNLDDICFTLEYQFENQKLVQVQPPTVVSLSMLAPASEGVSPILPNCDNGQGIVNVNSNSNSMEATSPAYFTVETSYVDDYDQNELDEDEQLAHCIQPGVLHKDDQEYEEDEVGHQDENDQLMALAYESSDEALSRYRCNYENCYRSYSTIGNLRTHLKTHTGDYSFKCPEDGCNKAFLTSYSLKIHVRVHTKVKPYECEVTGCDKAFNTRYRLHAHLRLHNGETFNCELCQKCFTTLSDLKKHMRTHTQERPYKCPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQLTNKGRKKRPLKPQQGKLTDLEQDQENLQDQSQLEEQEEGEERSEMMALNPGSQCSETTSTDSGVVLHTLTGQDQLQSVFILPEDQPLTLPETSQAYQLSYAAEEEIPSPWSDAGVLLSKPIIPMAPVTDACVALPTEMPSFVDLKPTFGNGVSGNMEQPQAEIMEVETVAPPLPTPTLELNLQNIEELLKQDSSFDNEEDMETDSLLNDILMTIDNNSALLQETLHQASQVPTDASGLVELDIRDNKPTLKQITADAGICNCTNCKCDQTKSCHGGDCGASSQKPTRTTTTTLATPKPSGGKRICGSKKVSKREAEMNQNIEDVALLLQNLASMGNASSSGGGCCGGGAAKPAPTTGGCCGEPKIQPEPTKSCGSSSSGGGGCCGGGGAPAAPPSQSSGGCCSSNKPAPAPAPTPPSASGCCSGKAKAQEPPVITNAPATAVKGSSCTCKSPAEGVANGCCVVICIKTLQALRKVLTRRNLNLMLCPQQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615123;
90% Identity: iTF_00550503;
80% Identity: -