Basic Information

Gene Symbol
-
Assembly
GCA_018150695.1
Location
JAECWM010000289.1:332946-335338[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.057 4.2 8.0 5.9 3 23 162 182 160 182 0.96
2 12 0.00098 0.073 13.5 0.5 1 23 188 213 188 213 0.94
3 12 0.003 0.22 12.0 1.3 1 23 220 245 220 245 0.95
4 12 0.23 17 6.1 1.1 1 11 257 267 257 270 0.91
5 12 1.9e-06 0.00014 22.0 0.2 1 23 286 308 286 308 0.98
6 12 0.0056 0.41 11.2 0.1 1 23 314 336 314 336 0.98
7 12 0.0054 0.4 11.2 4.0 1 23 342 365 342 365 0.98
8 12 0.0073 0.54 10.8 3.9 1 23 371 393 371 393 0.96
9 12 0.00012 0.0092 16.4 3.6 2 23 400 421 399 421 0.96
10 12 3.3e-05 0.0024 18.2 0.3 1 23 528 551 528 551 0.96
11 12 0.0086 0.64 10.6 1.2 1 19 557 575 557 579 0.94
12 12 1.4e-06 0.00011 22.5 4.1 1 23 585 607 585 607 0.99

Sequence Information

Coding Sequence
ATGTGGCTGGGAAACGAGGCCGATTTGGTGGGCCAGGAGGAGGAGGACCGCATCAACTTCGATCCGTTGCTGGACCACAAAATGGAGCTGATCGAGAACGAGGAGGATGTGTTTAAGATGCTGGAGCACGTGGACAAGGAGGCCGAGCAGGTGGAGAAGGAGGTGAAGCAGGACGAGCTCGATGCCGCTGACCTGATGACCATCTTCGCGGCGGACTCCTCGGAGGAGAGCGACGACGACGACTTCGAGCAAGACATGGACTTTGAGCCCAACAGCACCGATGGAGACGACGACTTGCCCCTGGCCCAGCGCTTGAGAGTCAACTCGAGGGTGAAACCCAAGGCCAAGCGGTCCGCCATCAAGGAGGAGGAGCTGGAGTTTCTTTCGGGCTCCGAGGAGGACGACGAAGAGGACGGGGAGAAGTCGAAAAGCAGGCGCAGGAGGATTCCGGCCGGCGAACGCCACCTGCACCGCATCATAGACTGTCACATCTGCCACCAGAAGTTCAAGAAGGCCATCCGTTACGAGGAGCACATGAAGCACCACAACGATCTCCTGCCCTTTCAGTGCAAAGTGGAGACCTGCAGGAAAGGCTTCACCACCGCTGGCGGATTGAGGCTGCACATTGATCACGCCCACACGGAGCTTTCGGAGGTGCATTCCTGCAGCGTCGACGGCTGCGGCAAGAGCTTTCCGCGCATCCGCCTACTCACCTTCCACATGAAGAAGATGCACGGCATCACGAAGGCGGCGGCGCCGCCACGGGATTACCCCTGCTCCGAGTGCGAGAAGGTCTTCCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCAAGGAGCTGCCTTTCCCCTGCAATATCTGCGGCAAGCGGTTTGTGATCAACAGTGCCCTAAAGGATCACCTGATGAGGCATGCGGGCATCAAGAACTACGTGTGTCCGTACTGCGGCGTGGGCAAGACCACGCGGCAGGAGTGGAACACGCACATCTTGACCCACACGCAGGAGAAGAAGTTCAAGTGCCACATTTGCGAACACGCCTCCCACAACAAGCAGAGCCTGGCCAACCACATTAAGATCGTACACGAAAAGATCAAGAACTACGCGTGCCAGTACTGCGGGAAGACCTTTGGGAAATCGCATGCCTGTAAAATTCACGAGATGACGCACACGGGGGAAAAGCGCTGCGAGTGCAAGGTCTGTGGCAAAAAGTTCCTCTACCCCAAGAGTCTCACCAAACACTTGAAGACGCACGAGAAGCGGGTTCTGCGGGCCATCGAGACCTATCGACAAAGGCAGGTGGAGATGGGGGAGACTGCCGGTGACCAGATGGACAATCCTCCAGCCATGGCTCTAGAAACTCCCTCGTCCAGTGAACCGATTATGTCCCAAAACGCCGCTAACGAATTGCTCAAGGTGTGCGCTGAGTCCGTGGCCACCATACCCAAGGATCCGCGCCGTGTGCAGCGGGTGGACCTTGCCCAGTTGGCTGGGACTGCTGTAAATCCTATACCCTCAGTTTCAGTGCCCTCGTGGTCACCCCAGGTCAACTTCACCAAGAAGGAGGGCAAGCACATTTGCCCGGGATGTGGACAGGGATTTAACAACATCGGGAACATGAAGCGGCACTACAAGATCATCCACGAGAAGGTCAAGGACTTTGCCTGTCGTTTCTGTCCCAAGAGATTCGCCAAGGCCCAGACATTGAGGCACCACGAGTGGATCCATACGGGCGAGAAACCCTTCGAGTGCAAAACCTGCGGCACCCATTTCCGCCAGGAGACGGCCCTCAAGCGCCACCAGCGTACCCACGAGAACCGTCCGCCCGTGATCTCGCCCAAGTTCTATGCCGCTCGGGAGGAGCTGGAGGAACAGGAGCGAAGCAAGCGGGAGGCCAAGCGACAGGCGGATGCCAAGCGACGCGAGATCGCCGAGGCGGCCAAGGAGCAGCTCTCTTCGCTGCACAAACTGGAGGGCAACGATCGGAACCTGAGCTCCTACGATGAATACCAGGAGGCGGCGGCAGAGCGGGCAGCTGCATCCGCGGAACTCCAGGCGCAGCAGTTCGAGGAGAACGAAGTGAAGCGCAGGGCGGACGAGGAGCGGATCAAGATACAGGAGGCTGCCTACGAGCAACTGCAGCGGCTGCAGCACCAGCAGGAGATCGACAAAGCGCAGAGCTCCTACGATGGCTATTACGCACAGAAGGCAAATGCCGATGGCACCAGTTTGGACGCTTTAAAAATCGACCATGTCTGA
Protein Sequence
MWLGNEADLVGQEEEDRINFDPLLDHKMELIENEEDVFKMLEHVDKEAEQVEKEVKQDELDAADLMTIFAADSSEESDDDDFEQDMDFEPNSTDGDDDLPLAQRLRVNSRVKPKAKRSAIKEEELEFLSGSEEDDEEDGEKSKSRRRRIPAGERHLHRIIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVETCRKGFTTAGGLRLHIDHAHTELSEVHSCSVDGCGKSFPRIRLLTFHMKKMHGITKAAAPPRDYPCSECEKVFRXXXXXXXXXXXXXXKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQEKKFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHEKRVLRAIETYRQRQVEMGETAGDQMDNPPAMALETPSSSEPIMSQNAANELLKVCAESVATIPKDPRRVQRVDLAQLAGTAVNPIPSVSVPSWSPQVNFTKKEGKHICPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPKRFAKAQTLRHHEWIHTGEKPFECKTCGTHFRQETALKRHQRTHENRPPVISPKFYAAREELEEQERSKREAKRQADAKRREIAEAAKEQLSSLHKLEGNDRNLSSYDEYQEAAAERAAASAELQAQQFEENEVKRRADEERIKIQEAAYEQLQRLQHQQEIDKAQSSYDGYYAQKANADGTSLDALKIDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00504136;
90% Identity
iTF_00581692;
80% Identity
-