Dosh005859.1
Basic Information
- Insect
- Drosophila oshimai
- Gene Symbol
- Paris
- Assembly
- GCA_018150695.1
- Location
- JAECWM010000048.1:656455-657495[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 1.4e-06 0.00011 22.5 1.1 1 23 126 148 126 148 0.98 2 8 8.4e-06 0.00062 20.0 1.4 1 23 154 176 154 176 0.98 3 8 2.3e-06 0.00017 21.8 1.2 1 23 182 204 182 204 0.98 4 8 2.3e-07 1.7e-05 24.9 1.9 1 23 210 232 210 232 0.99 5 8 4.8e-07 3.6e-05 23.9 8.1 1 23 238 260 238 260 0.98 6 8 4.6e-05 0.0034 17.7 4.5 1 23 266 288 266 288 0.98 7 8 1.7e-05 0.0013 19.1 2.7 1 23 294 316 294 316 0.97 8 8 0.00076 0.056 13.9 4.8 1 23 322 345 322 345 0.97
Sequence Information
- Coding Sequence
- ATGGAGCAAATCTGCCGTGTTTGCCTGGGAAGATCCGAGAACTTGATTAACATATTCGATGCAAGGCGTAGATCCAGCCTCAGAGTTTCCATCGCCGAGATGATCTCGCAGTGTACCGGATTTGAACTTAAAAGAGGCGACTCTTTACCGGAAACCATCTGCCCGCCGTGTCTGGAAGATGCACAGAATGCATTTAACATAAAGCAAACGTTCGAGAGGAGCCACCAGTTTTTCTGCCAAGCTCGGGATGAGGGCATTGAAGAGGCACTATGCGCGCTGCTGGAAGAAGAGGACTGGGAGTTGTCGGAGAATGAAGGCGAATGGAAAACTTCTGAGGCCGAAGACGATGGACAAATTGACCTCAAACAAGTAACATTTGAATGTCGAAACTGCCCGAAGCGGTACAAGAGCAAGGGTGCGTGGCTGAGGCACATGAGAACCCACTTGGATGGCGAATCCTTTGCATGCAAGTACTGTTCACAGAACTTTAGACTTAGGGCCAAACTGAGAGCGCACATTAGGACGCACAACGCAGATAAGCCTTACGAGTGTACTCACTGCTCATTGGCCTTTGCACAGCAATCCACGCTTCAGTCGCACGAACGGATCCACACAGGCGAACGTCCATTTCAGTGTTCCCAGTGCCTCAAGACCTTTGTCAAATCGTCTGATCTAAGCCGACACATCCGCACCCACGGTGGCTTACGCCCGCACAAGTGCAGCAAGTGCTCGAAAACCTTTACGAGGAAATCACATCTTGAAAACCATCTTCGCTCTCATTCGGGAGAACGACCACACCAGTGCTCCCAGTGCTCCAAATCGTTTGCTTTAAAACAGCATCTTAAGGAGCACGTTCGCATTCACTCGGGGGAACGGCCTTTCAAGTGTACGCAGTGTTCCAAGTCTTTTGGCCAAAGGTCCACTCTCAGGGATCACACGTTTGTGCACAGTAAGGAGCGATTATTCAAATGTTCACACTGTTCTCAATCTTTCAAGCTAAGGAGAACACTAGGAAAGCATATCCTCAAACGCCACTCATGA
- Protein Sequence
- MEQICRVCLGRSENLINIFDARRRSSLRVSIAEMISQCTGFELKRGDSLPETICPPCLEDAQNAFNIKQTFERSHQFFCQARDEGIEEALCALLEEEDWELSENEGEWKTSEAEDDGQIDLKQVTFECRNCPKRYKSKGAWLRHMRTHLDGESFACKYCSQNFRLRAKLRAHIRTHNADKPYECTHCSLAFAQQSTLQSHERIHTGERPFQCSQCLKTFVKSSDLSRHIRTHGGLRPHKCSKCSKTFTRKSHLENHLRSHSGERPHQCSQCSKSFALKQHLKEHVRIHSGERPFKCTQCSKSFGQRSTLRDHTFVHSKERLFKCSHCSQSFKLRRTLGKHILKRHS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -