Basic Information

Insect: Drosophila oshimai
Gene Symbol: -
Assembly: GCA_018150695.1
Location: JAECWM010000296.1:126097-133242[-]

Transcription Factor Domain

TF Family: THAP
Domain: THAP domain
PFAM: PF05485
TF Group: Zinc-Coordinating Group
Description: The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 6.3e-14 9.1e-11 42.3 1.9 1 87 16 85 16 85 0.81

2 16 1.2e-10 1.8e-07 31.8 0.4 1 86 167 233 167 234 0.78

3 16 3.2e-05 0.046 14.4 0.0 1 59 249 297 249 310 0.79

4 16 8e-12 1.2e-08 35.6 0.1 1 87 326 396 326 396 0.83

5 16 1.7e-12 2.5e-09 37.8 0.5 1 87 455 525 455 525 0.82

6 16 7.7e-11 1.1e-07 32.4 1.4 1 86 560 631 560 632 0.80

7 16 4.5e-10 6.6e-07 30.0 0.0 1 86 642 713 642 714 0.78

8 16 1e-11 1.5e-08 35.3 0.0 1 86 738 808 738 809 0.76

9 16 4.9e-05 0.072 13.8 0.1 1 58 839 886 839 911 0.75

10 16 2.9e-13 4.2e-10 40.2 1.1 1 87 924 996 924 996 0.81

11 16 4.7e-16 6.8e-13 49.1 0.1 1 86 1104 1176 1104 1177 0.81

12 16 2e-12 2.9e-09 37.5 3.0 1 86 1236 1306 1236 1307 0.80

13 16 7.3e-14 1.1e-10 42.1 4.4 1 86 1398 1468 1398 1469 0.84

14 16 1.4e-11 2e-08 34.8 0.2 1 86 1543 1612 1543 1613 0.84

15 16 8.8e-11 1.3e-07 32.2 1.1 1 58 1636 1684 1636 1696 0.84

16 16 8e-11 1.2e-07 32.4 2.6 6 87 1695 1760 1691 1760 0.74

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	6.3e-14	9.1e-11	42.3	1.9	1	87	16	85	16	85	0.81
2	16	1.2e-10	1.8e-07	31.8	0.4	1	86	167	233	167	234	0.78
3	16	3.2e-05	0.046	14.4	0.0	1	59	249	297	249	310	0.79
4	16	8e-12	1.2e-08	35.6	0.1	1	87	326	396	326	396	0.83
5	16	1.7e-12	2.5e-09	37.8	0.5	1	87	455	525	455	525	0.82
6	16	7.7e-11	1.1e-07	32.4	1.4	1	86	560	631	560	632	0.80
7	16	4.5e-10	6.6e-07	30.0	0.0	1	86	642	713	642	714	0.78
8	16	1e-11	1.5e-08	35.3	0.0	1	86	738	808	738	809	0.76
9	16	4.9e-05	0.072	13.8	0.1	1	58	839	886	839	911	0.75
10	16	2.9e-13	4.2e-10	40.2	1.1	1	87	924	996	924	996	0.81
11	16	4.7e-16	6.8e-13	49.1	0.1	1	86	1104	1176	1104	1177	0.81
12	16	2e-12	2.9e-09	37.5	3.0	1	86	1236	1306	1236	1307	0.80
13	16	7.3e-14	1.1e-10	42.1	4.4	1	86	1398	1468	1398	1469	0.84
14	16	1.4e-11	2e-08	34.8	0.2	1	86	1543	1612	1543	1613	0.84
15	16	8.8e-11	1.3e-07	32.2	1.1	1	58	1636	1684	1636	1696	0.84
16	16	8e-11	1.2e-07	32.4	2.6	6	87	1695	1760	1691	1760	0.74

Sequence Information

Coding Sequence: ATGCCACTTCGTCGTGAGAAACCGGCGAACAATGTGACACCCATTTGCTGCTTGAAGCACTGCAGAAAGGAACGCACCGCTTTTCACCTGCTCAGTACATTTGGTTTTCCCAAGGATCGCACGCTGCTGCTGAAGTGGTGTTCTAATCTCCAGCTAAATCCGGACGACTGTATTGGACGTGTTTGCATCGAGCACTTCCAGCCGGAGGTACTTGGCACCCGTAAACTCAAGCAGAACGCTGTGCCCACTATTAATGTGGGACACGAAGAGTCTCTTAGGTACTCGTGCAATGGCCTGGATCTGGATCAGGACGAATCACATCCCCAACACTCGGTTTTTCGGCTTTGGAGCCTGAAACACTGCCGCAAGAGGAAGCTGACAGAGCCGCCCGACATTCGCCCGAACAAGTGGAAGGCAGCGGATGTGCAGATGAAGCGGAAAACAAAGATGGTGATGAACCCTCTAGCGAAGAATCTGACGGAGAGTAAACTGGAAAGATGTTGCGTTATCAGCTGTGCAAACGAGGATATCAAGCAATTGCTTCCTCTGCCCGAAGAGCGACTCCTGCTTAGAAAGTGGCAGCATAACTTGAAGCTGTCCATGGACTCGATGCATAGTGAGATTCGCGTGTGCCTGGAGCACTTCGAGCCGCAAGTTGTGCGCAACGAAAAGCCCTCGGAGCAGGCAGTACCCACTTTAAAATTGGGCCTCAATAGGTGGAACCTATACAGAAATAATGGGCTGTGCCTTATGCCCAATTGCCCAAGTGGCCTCACGGATCGCGGCAGCTTTGTTGATTTGCCTGGAAACATGGTAATAAGGATCGAATGGCTGTCATACCTCAAGCTACAACTCAACAGTGAGGGACATATATGTGGCAGCCACTTTATGGAGGTGTCTGAGAAGGTGGATTTGCCAAAAGTTTTGTCCGCACTAGATTTGGAGCTGCTGCAGTTGACTCTTGATGAGTTCAAATGTGCTGTACCCGGCTGCTCCTCCACGATTGTCGAAGATATCCAGCTCACGCAGCTTCCAGATGAGGAAGTGACGCTTTCCAAATGGCTGCACAACACTAAGATTGCCTACGATCACTCCAGGAGTAGAAGTTATCGCATCTGTTTGTTACACTTCGAACCAGCGTGCTTAGAGGGGGATATTCCGAAAGCGTGGGCCATACCCACGTTACATCTTAACCATGAGGATAGGGTTCACCTTAATCCTAGGCTGCAGAAAGAGCAGGAACGCTGTGAAACTCCCAATAGCAGTCACAGGCTTACTCCTCTGAGGATTAAAACAGATCTCGCTTCCCTCGGTAGTCCCAGTGTCAGTGCAAGTCCAAGTCCGCGGGGCAGGATAAGGATATGTTGCATTTCCACATGTGGACAGTTCGGAAATAGTCAAGTGCGGCTCTACCGCTTTCCCACCGAAGAGCAGGCCCTGCTCCGCTGGCTGGTGAACACACAGCAGCAGCCTCGTCTCGTAGATCCCCTGGAGCTTTATGTGTGCCAGTCCCACTTTGAACCCGATGCTATATGTAAGAAGCAGCTTCGCAGCTGGGCGGAGCCCACCTTGAATCTCGGCCATGACGGTCATGTGATCCCCAATGCCAGGCACAACGGAAACATAGCCGATAGCCAGGAGACCGAGCAGGCGATGAGATTTATCAGACAACGCTTTTGCTCTGTGTTGACTTGTTTCCAGGCTGAATGCAAGGAAGTGAGGCTATATGAGTATCCGCAGGATATGGCCACTATACGAAAGTGGGCAGCCGCATGCAGACATCGCTCCATGCAAGCCAGGAGTCATGGGTTTAAGGTTTGTCAGTCCCACTTCGCCCCGGAATGCTTCCATTCGGAGACTTTAGATCTGATTGACGGATCTGTTCCCACACTGGAATTGAGCAGGGATGACATGGAAAGACACTGTCTGGTGTCGGGCTGTGTAAGGGACGTGACTGGAGATCGTCTCCGCTACTACAAGGTGCCAAAGACCCATGCTCAGTTGGATGCCTGGAGCACCAACCTTAAGATTCAGTCCATGGACCTCATCCAAGGAGAGCAGTACATCTGCGAGCGTCACTTTGAACCTTTCTGCTTCGGTGCGAGCAAGGGATTGCGAACGGGTTCGCTTCCAACACTCTTGTTGGGCCATGACGAGGACGTAGATGTCTTACCCAATCCTGAAAGCCTCCTGCAGAGCAAAACGGAGGTGTGCTGTGCCCTTGGCTGCGGACGTATTTGGCAAACGGGAGATCCTTCGTTCAGGAGTTTTCCCAAAGCTTGGACGCTGGCCAACAAATGGATCCATAACCTCCGCCTCACAGCCACCAAGGAACAGCTGGGCAGGCTGAAAATCTGCAGTGCTCATTTCGAAGCCTCTCTCTATGATAAAAGTGGATTACCATCGGGTTCGATGCCCACCCTGGAGCTGGGCCATTCCTCTCCGGATATTTATGAAACGGATAAGGAAACTTTGGGCAAAAGCTTTAAATTCCAGAAGCAACCTGATTTGGATTGTTGTTATCCCCAGTGTGGAGAACTTTCCAAAAACCTGGCTTATGGCCTGCCCCAAGAGGAGCAACTTAGAAGAACCTGGCTGCGTCACATGGACATCGAAGAGCCGGAGAATGGTGTCGCACAGCTCTGCCCACTCCACTACGTTATTCTCTATGAGCACAGCGCCCAGAGTTTTCAGGGCCATGTTTCAAACCGCTTCCTGGAGGATAATTACCATGCTGCTCGAAACAACCGGCGCGTGAGGATCGTAAGCTGTGCAGTAAGAGGTTGCGACATGATCAGGCCCCGGGATAGGGTTTCTCTGCATGGGATGCCGCACAGGAAAGACATTCTGCAAATGTGGGTGGAAAACGGCCAGCTGGAGTTTTGCGAGCAGCAACGATACATGTTCAAGATATGCCGCAATCACTTTGAGTCCCAATGTTTCTTCGACGACAGGCGGTTGCTCCCTTGGAGCGTTCCCACGCTGCACCTGCCATCAAAGCCACTGCACCAGAACCCCACCAAAGAGGAGTGGCAGGAGATGACGGCCAAATTGGCTCAGGAAACCGGAACAATCAAAAAGGAGACGGAAGATGAGGAGGGGGTAGAGGATGATAACTCACTTTTAGAGCCCATTGTGAGGATTGAGCACATCGAGTCCGAGGAGGAAGACTCTGAAATGCAGGCCTTGGAGGTGCTACTGGAAGTGGGACATGTGGAGCGAATGGACAGCTACGAAAATGTGGACGAATCCCGAGTAGTCTATACCGATCAGTCCACTGGCATTCGGAATCAGTACAATGCCAACCACTGCGCCGTGGAGGGATGTGAGGTGACTGCTGAGGACGTGGACGGAACTATCAAGCTGCACAAGTTTCCAGCTTCGCCTGATGCCGCCCAGAAGTGGATGCACAACACTCAAGTGCACATGGACGGGAAGTTCTGGTGGCGCTATCGGATTTGCAGCTACCATTTCGACCAGGAGTGCTTCCAGGGGGCGAGGATCAGGAAAGGAGCCATGCCCACGCTGCTCTTAGGAAATAAAAGACCGGAAAAGGTGTACGACAATGAGTTTGCACCACCAGAAATGGAAGAGCCTTCTTTGCCAGCAGATGATCAGTCAGAGGAGCACAAGGAGCCATCAGTTCGAGAGGTGTCCCACCTATGCCTCCCTTCACCGGCTCCCCCTCGAAAGTCCAGCAAGTTCTGCCAGATAGAGGGATGCAATAATCACCTCACCACCGAGAACATGACGCTGCATAAGTTTCCCCATTCGGAAGACATGTGTCTCAAGTGGCAGCACAACACGCAGGTGCCCTTCGATCCATACTACCGGTGGCGGTACCGCATTTGCACTGCTCATTTTCATCCCGTTTGTCTGGTCAACATGCGGCTTGTCCATGGGAGCGTGCCCACCTTAAAACTGGGACCCAAGGCTCCGGCCGAGCTCTACGACAACGACTTCGAGGCCATCAATATGAGGCTAGACAAGAGGACGGGAGCAGAGATCCAGATCAAGGAGGAAAGGGAGGAAGATGAAGACTCTCTGCTGTTCCTGGAGCCTGAACTGCAACTGCACGAAGACCAGGAGGAGGAGATTCCCTTTAACCAGTCCAACTGGAAGAGCCAATTGCGCCTGCCCGTCAAGCAGGAGAAGGTGTCCTACAACCAGGTAAAGTCCGGCTACGATAAGTGTTCGTTGGGTCACTGTCAGCGACAGAGATCTAAGCACGGCGTCCACATCTACAAGTTCCCCAAATCAAGGCGCCAACAGGAGCGTTGGATGCACAACCTTCGCATCCGCTATGATGAGCGGCGGCCCTGGAAGTTCATGATCTGCAGCGTGCACTTTGAGCCACACTGTATCAGCCTGAGAAAGCTGCGAAACTGGGCAGTGCCCACTCTGGAACTAGGTGACAACGTGCCCGAAAAAATCTTTACAAACGAACAGTGTCAAGAGATCCCTAGTGAAGCGGAGACTGAAGCCGATGAGGAAGACGGCTTGCAGGAGGACGATGAAGATGATGACGAAGATTTGGAGGAGGAAGCTCCCAACAAAAAAAGAGAGCGTCGTTCCAAACTGGATCCCTACCCTCCTGGTCAAGTCCCGCCTTGGAAAGTCAAGCAGTGCTGCCTTCCGTACTGTCGCGCCTTTCGTGGCGAAGGTATCAAGTTGTTCCGGCTGCCCAACAACAGCACCTCCATCCACAACTGGGAGCTGGCCACCGGTATGGTCTTCAAAGAGTCGCAACGAAACACTCGGCTAATCTGCAGCCGCCACTTTGAGCCGGAACTTATTGGTGTGAGGCGTCTCATGCGCAACGCTATTCCCACGAGGCATTTGAAGCCACTAGGAGCCCAAGACGAGGCCAAAAGGAAGCCAGATCCTCCCGTCCCCATTGCCACCTGCTGCATGGCTGACTGCCACTACAAAGGAAATGTCAAGCTGCACAAGTTTCCCAATGATCCAACGCTTCTTAAACAGTGGTGTCAAGCTCTCAGGCTTACGGATACGCAGCGATACCGAGGCAAGCACATTTGCTCGATCCACCTGCCCACCGACAAGACGATGAGCTGCGTCGTCTGTGGGGTGGACAAAGTGCAGTTGCCGATGCTTAACTTTCCGGAGCAACGCAATCAGCGCGCTAAATGGTGCTACAATCTAAAGATCGAGACCATACCCAAGTGGGACCACTCAAAGCACATCTGCTGCCGTCACTTTGAGTCGCACTGCTTTGTCCGAACGGGTGAACTGCGTCCAGGAGCGATTCCCACGCTGCATCTAAACCACCACGACACAAACATATTCCTCAGCGACTACGCCACTGGACCGCTCACGGGCAATCGGATTAAAGACGAGCCACTGGACAGCGACGAAATGCTGCTGGTGTAG
Protein Sequence: MPLRREKPANNVTPICCLKHCRKERTAFHLLSTFGFPKDRTLLLKWCSNLQLNPDDCIGRVCIEHFQPEVLGTRKLKQNAVPTINVGHEESLRYSCNGLDLDQDESHPQHSVFRLWSLKHCRKRKLTEPPDIRPNKWKAADVQMKRKTKMVMNPLAKNLTESKLERCCVISCANEDIKQLLPLPEERLLLRKWQHNLKLSMDSMHSEIRVCLEHFEPQVVRNEKPSEQAVPTLKLGLNRWNLYRNNGLCLMPNCPSGLTDRGSFVDLPGNMVIRIEWLSYLKLQLNSEGHICGSHFMEVSEKVDLPKVLSALDLELLQLTLDEFKCAVPGCSSTIVEDIQLTQLPDEEVTLSKWLHNTKIAYDHSRSRSYRICLLHFEPACLEGDIPKAWAIPTLHLNHEDRVHLNPRLQKEQERCETPNSSHRLTPLRIKTDLASLGSPSVSASPSPRGRIRICCISTCGQFGNSQVRLYRFPTEEQALLRWLVNTQQQPRLVDPLELYVCQSHFEPDAICKKQLRSWAEPTLNLGHDGHVIPNARHNGNIADSQETEQAMRFIRQRFCSVLTCFQAECKEVRLYEYPQDMATIRKWAAACRHRSMQARSHGFKVCQSHFAPECFHSETLDLIDGSVPTLELSRDDMERHCLVSGCVRDVTGDRLRYYKVPKTHAQLDAWSTNLKIQSMDLIQGEQYICERHFEPFCFGASKGLRTGSLPTLLLGHDEDVDVLPNPESLLQSKTEVCCALGCGRIWQTGDPSFRSFPKAWTLANKWIHNLRLTATKEQLGRLKICSAHFEASLYDKSGLPSGSMPTLELGHSSPDIYETDKETLGKSFKFQKQPDLDCCYPQCGELSKNLAYGLPQEEQLRRTWLRHMDIEEPENGVAQLCPLHYVILYEHSAQSFQGHVSNRFLEDNYHAARNNRRVRIVSCAVRGCDMIRPRDRVSLHGMPHRKDILQMWVENGQLEFCEQQRYMFKICRNHFESQCFFDDRRLLPWSVPTLHLPSKPLHQNPTKEEWQEMTAKLAQETGTIKKETEDEEGVEDDNSLLEPIVRIEHIESEEEDSEMQALEVLLEVGHVERMDSYENVDESRVVYTDQSTGIRNQYNANHCAVEGCEVTAEDVDGTIKLHKFPASPDAAQKWMHNTQVHMDGKFWWRYRICSYHFDQECFQGARIRKGAMPTLLLGNKRPEKVYDNEFAPPEMEEPSLPADDQSEEHKEPSVREVSHLCLPSPAPPRKSSKFCQIEGCNNHLTTENMTLHKFPHSEDMCLKWQHNTQVPFDPYYRWRYRICTAHFHPVCLVNMRLVHGSVPTLKLGPKAPAELYDNDFEAINMRLDKRTGAEIQIKEEREEDEDSLLFLEPELQLHEDQEEEIPFNQSNWKSQLRLPVKQEKVSYNQVKSGYDKCSLGHCQRQRSKHGVHIYKFPKSRRQQERWMHNLRIRYDERRPWKFMICSVHFEPHCISLRKLRNWAVPTLELGDNVPEKIFTNEQCQEIPSEAETEADEEDGLQEDDEDDDEDLEEEAPNKKRERRSKLDPYPPGQVPPWKVKQCCLPYCRAFRGEGIKLFRLPNNSTSIHNWELATGMVFKESQRNTRLICSRHFEPELIGVRRLMRNAIPTRHLKPLGAQDEAKRKPDPPVPIATCCMADCHYKGNVKLHKFPNDPTLLKQWCQALRLTDTQRYRGKHICSIHLPTDKTMSCVVCGVDKVQLPMLNFPEQRNQRAKWCYNLKIETIPKWDHSKHICCRHFESHCFVRTGELRPGAIPTLHLNHHDTNIFLSDYATGPLTGNRIKDEPLDSDEMLLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -