Doch011908.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ochracea
Gene Symbol
-
Assembly
GCA_035044125.1
Location
JAWNML010000060.1:299794-316799[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 6.9 4.3e+02 1.6 0.5 1 23 50 73 50 73 0.90
2 8 0.035 2.2 8.8 0.7 1 23 735 757 735 757 0.95
3 8 1.8e-05 0.0011 19.2 1.1 1 23 763 785 763 785 0.98
4 8 3.1e-06 0.00019 21.6 0.2 1 23 791 813 791 813 0.98
5 8 1.7e-06 0.00011 22.4 1.2 1 23 819 841 819 841 0.98
6 8 0.0005 0.031 14.6 1.8 1 23 847 869 847 869 0.97
7 8 5.3e-06 0.00034 20.8 2.4 3 23 877 897 875 897 0.94
8 8 8.1e-06 0.00051 20.2 1.0 1 23 903 926 903 926 0.98

Sequence Information

Coding Sequence
ATGGCCGTAGAAATAACAAACTCAGTATTATCGCTGCAGCCGATGgcaattgaaactgaaacccCTCTCCACTGGCAGCTCGAGGACTATGCATATTTTCACAAATGTGGCGAGATTACAACCTCACCCGATGTCCAATGTTTTGGCTTCAATTGTGCATTCTGTCCGGCAATTTGTCTGCAGCTGTCAGTCTTCATCGACCACATACGGACGCAGCACATGCAGGATATGCGAAGGCGCTATGAAAATGCCGCCGCGGCTGCTGCCAGCGACGAGAAAATCGAGCAAACCACACAAACCGATTTAAATCTAATGGTAATGAATATGGACACGAGCACAACGGGAGCAGAAGCAGGAACTAATCCTTTgaccacaacaaataaacgCTTGAAAAAAACAGCGAGCAATTGGAATGagaatgtgaatgtaaatgtgaatgaGAATACTGCACCCATTTGGAACATGGAAATGGACATGGCTCTGGATTTGGTTAACATTGCGCcgacaacaagcaacaactacaacagcagcaacaacagcaacaatgcctCGCAATTACAGCTTGGCAACACGggaataacagcaacagcaaccacagctGAAAttgattatgtttatgttatgcAAAATCCATTGCCACCCTCGCCGCCACCCTCGACGGATGAGCAGCGAAGTCCGCGACTGCTGCACTCGATGGAGGCATTTGAATTGCTGCATGTTGACTCAACGATTGTCTCTCCACACATAcaccaacacccacacacacctgcacacacgtacacagcGACACCCTTGGACTCGGTGGGACTACTCACCACACCGCACCGTTATGAGACGCGACGCGTGGCAATGCAGCGCAAGCTTCGCGACGCGGAAAAGCAAACTGCCACAACTGCTGATGGAGAAGAACAAacgcagcaacggcaacagcaacagcaacagcaacaagaacaagaacaacagcagcaacaacaattgcaactacaattacaacagcaactggaggAGGAGAATGTGCTGGAACTAACGCCGCCAGCGACGCCGCCAACGCCGCTGCCCCCCACCTCGCCAACCAGCAGCGTTGCGAGCAGCGTCGACATGAAGTTGCGCACGCGTCGCGAACTGGAGCGGAATCGAGAGTTTGTTAGCTCCCTACTGGTGGCCTATGAGCGCAACGAGAAACTCTGGAATCCAAAACATCCCGACTACAAATACAATGCCAAGCGAAGCGTCTACGGTGAATTGGCGGCACCACTTCAGGCCGTCTTCCAGATGCCCCTAACTGGTCCCGAAATCTTTGCGGTGCTCAAGGAGCTACGTGGTCGCTATCGTCGCGAGCTCAGCAAACTGAACTCGCTGGGTGGCAAGTACAAGTCGCGACTCTGGTACTTTGAAAAAATGCACTTCTTGCGTGGCGTCATCGAGCACAAGCGGGCCGAACGGGAGGCAAAGAGCGAGTCcacagagagcgagaaatCGAGTGATAATGAATCCACGACCAAATCGGCTCAATATCGTGAGGTGCTCAGCTGCATCATTGACAGTTTCCAGCGACAGGAGAGTTTGTGGAATCCGCAACATTTTGACTACAACAATTGCTCCAAGAAGGAGCTGTATCGGGAGATCTCGGCGGAGCTGCGCGAGGAGCTCAACTATGAGTTGAGTGGCGAAGAGTGTTTCAAGGAGATACAAAAGTTGAGGACTCGTTATCGCAAGGAACTGCGCATGGTGATCAAGCACAAGGGTCTCTATCTGCCAAAGCTTTGGTGTTACGATAATCTGGAGTTTCTCCACAAGATACTGCAGGAGCAGATCTTCAACAAGATAAGCAAGAAGAAGGGTGTCGTGGAAACCATTCAAAGGACTAAGTTCATCAATGCCAGCTGCATTAGTTTTGACACCCCCGACGATCAGCTGCAATTTGTGGAGATCTATCGCAACTATCCAGCTCTGTGGGATGTGGATCATCCCGATTTCCGCTCAAATGCCTATCGCAGTCAGGCTTTGGGTCAAATGCTCGAGGAGCTCACGACGACATTTCAATGCTCATATACTCCTGCGCAGCTTGAAAAGACGCTGTTCGAGCTGCGCAAGGATTACTCGGCACAAAAGCGTAAAATTCTCACGAATGCCTCCGGCTCGAGCAGTATTCCTTTGCTGCACGCGAAATTGGGCCAATTTCTCGAACCGAATCTCGGCCCCTTTCGCTGTGATGTGTGCGGAGAGCTGATCAAGACCTGTGATCAGTACAAGGTGCATCGTGCGGCTCACGATGGCACCCAGCCATTTATATGCACCCTGTGCGGCAAGGGATTCCAAATGCCATGCAATCTAACGGTGCATATCCGTCGACATCGTCGGGACTTTCCCTATGCGTGCGAACAGTGCGACAAGAGATTCGCTACCTCTACCGAGGTGGCCATACATATGCGCACCCATACCGGGGAGCGACCCTATATCTGTGATCTGTGCGGCAAGTCCTTCAAGACGTGGTCCTTCTTCGATATTCATCGGCGCACGCATCTCAATCAGTCCACGTTTCATTGCCCCATCTGCGATAAGGGTTTCTATGAGAAGAATCGCTTCACCGATCACATGAATGCCCACTTGAATATACGCAAGCATTTGTGCACCGTCTGCGGCAAGACCTTTACCACCTATGGCAACCTCAAGAAGCACACGGAACTACATTTGGCGGTTAAGAAGTACAAGTGTGCCACTTGTGGCAAGCGTTTTGCACAATTCGCCAGTTTACGCTGGCATCGGAAGCGTGAACACAActcggagcagcagcaacagcagccccgGCAATTAGAGGAGGAGCTAGAAGTGAATgtcgatgaggaggaggaggaggagacgTAG
Protein Sequence
MAVEITNSVLSLQPMAIETETPLHWQLEDYAYFHKCGEITTSPDVQCFGFNCAFCPAICLQLSVFIDHIRTQHMQDMRRRYENAAAAAASDEKIEQTTQTDLNLMVMNMDTSTTGAEAGTNPLTTTNKRLKKTASNWNENVNVNVNENTAPIWNMEMDMALDLVNIAPTTSNNYNSSNNSNNASQLQLGNTGITATATTAEIDYVYVMQNPLPPSPPPSTDEQRSPRLLHSMEAFELLHVDSTIVSPHIHQHPHTPAHTYTATPLDSVGLLTTPHRYETRRVAMQRKLRDAEKQTATTADGEEQTQQRQQQQQQQQEQEQQQQQQLQLQLQQQLEEENVLELTPPATPPTPLPPTSPTSSVASSVDMKLRTRRELERNREFVSSLLVAYERNEKLWNPKHPDYKYNAKRSVYGELAAPLQAVFQMPLTGPEIFAVLKELRGRYRRELSKLNSLGGKYKSRLWYFEKMHFLRGVIEHKRAEREAKSESTESEKSSDNESTTKSAQYREVLSCIIDSFQRQESLWNPQHFDYNNCSKKELYREISAELREELNYELSGEECFKEIQKLRTRYRKELRMVIKHKGLYLPKLWCYDNLEFLHKILQEQIFNKISKKKGVVETIQRTKFINASCISFDTPDDQLQFVEIYRNYPALWDVDHPDFRSNAYRSQALGQMLEELTTTFQCSYTPAQLEKTLFELRKDYSAQKRKILTNASGSSSIPLLHAKLGQFLEPNLGPFRCDVCGELIKTCDQYKVHRAAHDGTQPFICTLCGKGFQMPCNLTVHIRRHRRDFPYACEQCDKRFATSTEVAIHMRTHTGERPYICDLCGKSFKTWSFFDIHRRTHLNQSTFHCPICDKGFYEKNRFTDHMNAHLNIRKHLCTVCGKTFTTYGNLKKHTELHLAVKKYKCATCGKRFAQFASLRWHRKREHNSEQQQQQPRQLEEELEVNVDEEEEEET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00543926;
90% Identity
iTF_00513633;
80% Identity
-