Basic Information

Insect: Drosophila ochracea
Gene Symbol: Znf574
Assembly: GCA_035044125.1
Location: JAWNML010000050.1:403174-405450[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.035 2.2 8.8 0.4 2 23 341 363 340 363 0.96

2 10 3.2 2e+02 2.6 0.2 6 23 373 390 373 390 0.97

3 10 0.001 0.065 13.6 0.1 1 23 396 418 396 418 0.94

4 10 1.1e-05 0.00069 19.8 0.3 1 23 431 454 431 454 0.97

5 10 0.00012 0.0078 16.5 1.2 1 23 462 485 462 485 0.97

6 10 2e-05 0.0012 19.0 1.1 3 23 493 514 491 514 0.92

7 10 0.0011 0.066 13.6 0.5 2 23 526 548 525 548 0.97

8 10 7.9e-05 0.005 17.1 4.1 1 23 555 578 555 578 0.93

9 10 2.5e-06 0.00016 21.8 1.2 1 23 584 606 584 606 0.98

10 10 6e-05 0.0038 17.5 1.4 1 23 612 635 612 635 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.035	2.2	8.8	0.4	2	23	341	363	340	363	0.96
2	10	3.2	2e+02	2.6	0.2	6	23	373	390	373	390	0.97
3	10	0.001	0.065	13.6	0.1	1	23	396	418	396	418	0.94
4	10	1.1e-05	0.00069	19.8	0.3	1	23	431	454	431	454	0.97
5	10	0.00012	0.0078	16.5	1.2	1	23	462	485	462	485	0.97
6	10	2e-05	0.0012	19.0	1.1	3	23	493	514	491	514	0.92
7	10	0.0011	0.066	13.6	0.5	2	23	526	548	525	548	0.97
8	10	7.9e-05	0.005	17.1	4.1	1	23	555	578	555	578	0.93
9	10	2.5e-06	0.00016	21.8	1.2	1	23	584	606	584	606	0.98
10	10	6e-05	0.0038	17.5	1.4	1	23	612	635	612	635	0.97

Sequence Information

Coding Sequence: ATGGCAGCCTGTGTGCTATGCTTCGACTGCTGCAAGACCGGCGAGTCGTACAAGATATTTTCCGAGGCCGGATTGCGGCtcaaaatttgcaaaacaataaacaaacatttttggctgGAGCTGAGCAACGCAGCGGGAGGCGAACGCGAGGAAATTTGCCACCAGTGCTGGCAGGTCGTGAGcaactttaataaattatacgaGCGAGTCTACAACTTGCACCAGGAGCGCCTCTGTGATGTGAAGAACGTCACGATTGAATTCTGTGACGAGGCGGAGGCAGCGAATCCTCTAGCCCTTGGCGGTGAACTGGATGCACTCGCCGAGGATTTCTTTGCGTCCGGCGATGTCAAGGTGGAGGTGAATGAACTGGAGCCGCTGCCCAAGCTGGAAATACTCGATGAGCCAGTGGGCGAGGAGCAGAGCAGGGCATCCAAACGTGCCAGTGCCGAGCGTTCAGCTGCTAAGAGGCGCATCAAAAATGAACAGCTAACCCTCTCCAGTGACTCGGATGGGGACATTCCCTTAGCTGAGTTCCTTGATCTTAAAACGACTGCAAAACCAGGAGGAGTagtagcagctgcagcatcgcCGCTCATTGGACGACAGCTGCGAAGAAGCACTCGACGTGGTCGCCGAGAGAAAACCCCATCGGAATCGCCTTCAACCAGCTTGAAAAAGGAATCGGAATCTGATGATGCTGACcctgatggtgatgatgataataatgataatgatcaGGATATGGACTTTGTGGCCGCAGAAGCAGTGCTAGGCACTGAGGACAGTGCCAGTTCCAGCGAGAGTAGCGACAGCGACTCTGGCGACAGTCTGCCCGATGTCGAACCGGAGGAGCGCTACGCAGAGATACCCAAACGGGTCGTAGTCAAGCCCAAAAAGTATCGAAAGCGTCCCAAACCGCTGGTGGCGCCGGTGCGCATGAGTCGCGACGATCTCGCCAAGCGACGGgcgcaacaaaagaaatacgATGAGATTATATTTGAGTTTTTCAAGAAGCTGCCATGTCACGTATGCAATCTGTTGGTGCCCAATTTCGGAGACATGCGTCGTCATCTGCGCATGTCCCACAACATCGAGAGTGGCTTCATTGCCTGCTGTGGTCGCAAGTTTCACATACGCAGGGGTCTGGCCGAGCATGTGCTGGTGCACAATAACCCGGAGCACTTTATGTGCGCCCCGTGCGGTCGCGTCTTTCAGGACTCCAAGACGTTGGAGGCGCACGAGCAAACGCACACAAATCCCATGGCGGATGCGAAGGATAAACGCATTTACCCATGCGACAAATGTCCGAAAACCTTCACCACAAAGGCCGCCGTCGAGTATCACATTATGTCCAAGCATGTACCCAAGTCGGACTTCAAGTACACCTGCCCCGAGTGCAATAAGAAGCTGCCCACAGAGCGAAAGCTGAAGGAGCATCGACGATATATGCACGATCCGGAGACGGCAATCATTTGCGACAAGTGCGGCAAAACGTTGCGTACCCAGGCCAATCTTAAGAAACACCACGAATTGGAGCATTCCGATGAGCCACGCCCCAAGCCGGATCCCGTGCAGTGCGAGATATGCGGCACCTGGTTGCGCCATTTATCGGGCCTCAAGCAGCACATGAAAACGGTGCACGAACCGCCGTGTGGCGAGCATCGCTGTCCCATCTGCAACAAGACATCGACTAACTCCCGAGCACTCAAGCGGCACATTTACCACAATCATCAGTGCGAGAGAAAGTTCCGCTGCACCATGTGCGAGAAGGCCTTCAAGAGGCCACAGGATTTAAGAGAGCACACATCGACGCACACGGGCGAGGTGTTGTACACCTGTCCCAACTGTCCGCAGACGTTCTTCTCGAATGCCAACATGTACAAGCATCGCCAGAGATTGCATCGCGCCGAATGGGAGGCGGATCGCAAGAAACCACTGCCACCCAACATAATGCAGCAGGCGGCCATGAAGAAGCGACAGGGCAGCAAGGCTGCCGCACCCACGGTTTTCCCCCCATCCGCAGAGACGCCAACTGCACCAGCTGCCCAAAAGTTGGaatcgcaacaacaaccacaacaacaacaacaactgcattag
Protein Sequence: MAACVLCFDCCKTGESYKIFSEAGLRLKICKTINKHFWLELSNAAGGEREEICHQCWQVVSNFNKLYERVYNLHQERLCDVKNVTIEFCDEAEAANPLALGGELDALAEDFFASGDVKVEVNELEPLPKLEILDEPVGEEQSRASKRASAERSAAKRRIKNEQLTLSSDSDGDIPLAEFLDLKTTAKPGGVVAAAASPLIGRQLRRSTRRGRREKTPSESPSTSLKKESESDDADPDGDDDNNDNDQDMDFVAAEAVLGTEDSASSSESSDSDSGDSLPDVEPEERYAEIPKRVVVKPKKYRKRPKPLVAPVRMSRDDLAKRRAQQKKYDEIIFEFFKKLPCHVCNLLVPNFGDMRRHLRMSHNIESGFIACCGRKFHIRRGLAEHVLVHNNPEHFMCAPCGRVFQDSKTLEAHEQTHTNPMADAKDKRIYPCDKCPKTFTTKAAVEYHIMSKHVPKSDFKYTCPECNKKLPTERKLKEHRRYMHDPETAIICDKCGKTLRTQANLKKHHELEHSDEPRPKPDPVQCEICGTWLRHLSGLKQHMKTVHEPPCGEHRCPICNKTSTNSRALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQAAMKKRQGSKAAAPTVFPPSAETPTAPAAQKLESQQQPQQQQQLH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508523;
90% Identity: iTF_00616353;
80% Identity: -