Basic Information

Insect: Drosophila obscura
Gene Symbol: -
Assembly: GCA_018151105.1
Location: NW:11083108-11085259[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00055 0.034 14.3 4.4 2 23 424 446 423 446 0.95

2 6 8.4e-05 0.0052 16.9 1.6 1 23 453 476 453 476 0.94

3 6 0.00059 0.036 14.2 2.6 1 23 481 503 481 503 0.98

4 6 0.0016 0.098 12.9 0.5 1 23 509 532 509 532 0.88

5 6 1.9e-05 0.0012 18.9 2.3 1 23 538 560 538 560 0.98

6 6 0.00029 0.018 15.2 4.1 2 23 567 589 566 589 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00055	0.034	14.3	4.4	2	23	424	446	423	446	0.95
2	6	8.4e-05	0.0052	16.9	1.6	1	23	453	476	453	476	0.94
3	6	0.00059	0.036	14.2	2.6	1	23	481	503	481	503	0.98
4	6	0.0016	0.098	12.9	0.5	1	23	509	532	509	532	0.88
5	6	1.9e-05	0.0012	18.9	2.3	1	23	538	560	538	560	0.98
6	6	0.00029	0.018	15.2	4.1	2	23	567	589	566	589	0.95

Sequence Information

Coding Sequence: ATGGAGGTGTGCGGCAGTGTTTTAGTTAGCAACAATTACCAGCAGTTTCGGCTGAAGTGCATATACTGTACAATTGAAAGCGACCTAAAAGACTGGGAGCAGTTTACGTTTCATGTGAGAAATGCCCACTACTTTGAGGATGATGAAAACATTGAGCAAGAGTCAACCATCGAGGGAATGGATCCCACAATCACATATGAAGTTCCTCAAGAGTTGGACGAAGCGGAACACATTGAAGAAGTGcatgaccagagtagcttgcCATTTCGCATACTCAAAGACGAGGACTGGCCCAACGATGAGACGGATGAGAACAATATGCAATACGTCGAGGACATTGTTTATGACAATAACAATACAGAAGTCACATATCAGGAAATGGAAACGACCGAAATGGCGCAGGCCTCCTTCGATGAAAATGTGTACGACGGTTTCTTGAGCACTGGTTCTCAGCAGGCTGCAGTATTTGATGATCTAGATAATTTCTCGTATGATGAACAGGAAGAGGAACAGGAAGAAGAGTGGCCAAAAAGATTTGGCCGTCCTCCCAAAAGAACGCGACCTGGACAAGTTCTTAAGTTAAAGGTTACATTTATTCGACGCAATCCACGCGTGCTACACCTTATCGAAGCTTACAAGGAGCATCCCTGCCTATGGAATCCCTCCGACGAGTACTACGACAATGAGGAAGCACGATCGGAGGCGTACCACCTGATGATACTGCGATTGGACGAGAAAGCCAATGTGCTCTTCACCGAAGAAGAGCTGAGGAAAACCATCCAGCAGCTGCACAGCCAATACACTCTTGCAGCCCAAATGGCTGGCGAAAATAAGCTCATTGGGCTGGCGGCCCGATACTTTGCCAAATGTGATTTCCTCCGTTCCACGCCCTGTACAACCCTAACCGATGACGAGGAAGATATCCAACTGGATACAATTAAGCTCAACTTCAAAGTGGAGAACGAGGTGACCAGCGCTTTTATAGAAACGTATGCAAACTATCCAATGCTCTACAATACCATGCATACTGATTTTGATTCGGTGGAGGAACGCACAAGAGCCTACAAAAAGTTGGCCAAAGAATTCAGGCCTGTGGTTCTGGCCAACGATACGGATGTTTATATTGCGATCCAAAAGCTGCGGAAATGGGCATACGAAGCCATGAGGCGTATGAAGGCGAAGGAACTGATCAAAGCCTGCAGCTCACAGGAACTGCAGTACCTGCAAATGTGCAGCTTTCTGCCCGTCAAACCGGATGGCCATGTATGGTACTGTGAACACTGCGGAAAGCGATTCCATGGCGACTACAACCTCCGGACGCACATGTTCAAACAGCATAACATGGGTGAGCCGCCCTTCCTCTGCTCCCAGTGCCCCAGGCGCTTCGAAAGACAACATGACATGGAGAAACACATATTGAGAGCGCACTCTGATCGCCAATTTCAATGCAAATTTTGCGAAAAGCTTTTTTCCGTCGAGTGTGATCTGAAAGTGCACCTGAAAGTTCATACCGGCGAGCGCCCATATGTGTGTGAGTTTTGCGGGAAGGGGTTCcggctgaagctgctgctggatcacCATGTCAATGGTGTCCACCTGAATATACGGCCATTCAAGTGTGATATGTGCGAAAAAAATTTCAGAAAGAAATTTGAACTTATGAATCACCTCAAGGGGCATTTAAATATTCGTGATAAGAAGTGCGACAAATGCGACGCTACGTTCTATGACCATTCTTCGCTATCCCGACATCGTAGATTTAACCATAGAAATAAATTCGAATAG
Protein Sequence: MEVCGSVLVSNNYQQFRLKCIYCTIESDLKDWEQFTFHVRNAHYFEDDENIEQESTIEGMDPTITYEVPQELDEAEHIEEVHDQSSLPFRILKDEDWPNDETDENNMQYVEDIVYDNNNTEVTYQEMETTEMAQASFDENVYDGFLSTGSQQAAVFDDLDNFSYDEQEEEQEEEWPKRFGRPPKRTRPGQVLKLKVTFIRRNPRVLHLIEAYKEHPCLWNPSDEYYDNEEARSEAYHLMILRLDEKANVLFTEEELRKTIQQLHSQYTLAAQMAGENKLIGLAARYFAKCDFLRSTPCTTLTDDEEDIQLDTIKLNFKVENEVTSAFIETYANYPMLYNTMHTDFDSVEERTRAYKKLAKEFRPVVLANDTDVYIAIQKLRKWAYEAMRRMKAKELIKACSSQELQYLQMCSFLPVKPDGHVWYCEHCGKRFHGDYNLRTHMFKQHNMGEPPFLCSQCPRRFERQHDMEKHILRAHSDRQFQCKFCEKLFSVECDLKVHLKVHTGERPYVCEFCGKGFRLKLLLDHHVNGVHLNIRPFKCDMCEKNFRKKFELMNHLKGHLNIRDKKCDKCDATFYDHSSLSRHRRFNHRNKFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575109;
90% Identity: iTF_00611654;
80% Identity: -