Basic Information

Insect: Drosophila obscura
Gene Symbol: PRDM1
Assembly: GCA_018151105.1
Location: NW:207765-227897[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.9e-05 0.0018 18.4 2.5 1 23 968 990 968 990 0.99

2 5 8.6e-06 0.00053 20.0 5.1 1 23 996 1018 996 1018 0.98

3 5 1.8e-06 0.00011 22.1 4.3 1 23 1024 1046 1024 1046 0.98

4 5 0.0006 0.037 14.2 2.4 1 23 1052 1074 1052 1074 0.97

5 5 0.0001 0.0062 16.6 0.1 1 22 1080 1101 1080 1101 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.9e-05	0.0018	18.4	2.5	1	23	968	990	968	990	0.99
2	5	8.6e-06	0.00053	20.0	5.1	1	23	996	1018	996	1018	0.98
3	5	1.8e-06	0.00011	22.1	4.3	1	23	1024	1046	1024	1046	0.98
4	5	0.0006	0.037	14.2	2.4	1	23	1052	1074	1052	1074	0.97
5	5	0.0001	0.0062	16.6	0.1	1	22	1080	1101	1080	1101	0.96

Sequence Information

Coding Sequence: ATGCATGGACATCATCAcaatcatcagcagcagcagcagcaacagcagcagcaacagcagcagcagggacagcagcagcagcagcaccaacagacAGCAGCTGGAACTGCCAACAATATGAAGGCAGCgtcacatcatcatcatcatcatcatcctcatgtccaaacacatccacatccacatccgcatccgcatcacAAGCTGTCGACGAGAAGAACTGcgcgcagtcgcagtcgcagtcgtagTCGCAGTCCAACGCCCGATGGCAACCAGGACTACGATGTGACGCGTATGCGGGAGGAGGACTTTGAGCGTCTGGCCGTCTACCTAGTGCCGGATGTGCAGGCAGAGCGAGGACTATCCAATCGGGCGGACAAGACGCTGCCGCGCAGTCTGACACTCAAGTCATCGATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGTGGGGTCATACCGCGCGGCACACGCTTTGGCCCCTTCGAAGGCATTCCAACCTCCAACTATCCCAATGATAAGAATAAGGCGCGATATTTTTGGAGGgTGCAGGGAACACGCCACATATCCTATGGGATTATTAAGATCTTCAAGGACGACGACTATTACTATCTGGATGGCTCGGATCGTTCGCAGTCCAACTGGATGCGCTATGTGGCCTCTGCGTACAGCTTGTCGGTGATGAATCTGGTCGCGTGCCAGCATCTGGAGAACATCTACTTCTACACAACCCGCGACATCCTGCCCAATGAGGAGCTGATGGTCTGGTACTGCAAGGATTTCGCCAGCCGCCTCGGCTACGATGTGGATCCGGAGCGGACCATTTTCGGTGCCTGCAAGCAGGCCAGCGGCGAGGAGGATCTCGAGGAGGAGGccgaggaggcggaggaggagctcGAGGACCAGAATCAGGATCAGGATCACGATGGAATGCCGCCGCACAAGAAACCGCACTACTCCATGCCCGCACCCGAAATACCCGCCGAGGTGGCCGTCAGCCACATCACCTATGTGATGGGCCTCCATCTGCCGGCGACGCCAGGCGGAGCACCGACCCAGGGAGCCGGCAGCACGCAGGAAGCCCTGCCGCCTGCCCCACCGCCAACTGGTtctggtgccggtgccggtgccggttcCGGTTCCTGCTGTCGTCGCGCCAGTCCACCCGCCCACGTGTCCACCACCTCCTGTGGCGGCGCCCATCATCCGCACATCATCCAGCACGGACGGCATGCGTCCGTGATCATTGGCCAGGATCGCTCAccgctggccagcagcagcgacaaggACACCGCCGGCTCGCCGCTGTCCGGGCTGGACCACCAGCTGACGCCCCAGGATGGCAGCGTGCGTTCGGTGCGCTCGGATGAGGGCTACCACAGCAACGAGTGCCACGAGGATGGCCTCACGCCGCCCGAGGActccagcgacagcgagagcgAGCACAACTACGTCCTCGACTGCTCCAAGAAGGCCATTGCCCCCAAGGAGACGGTGATTGCCCAGGCCCAGAAGCCGCAGAGCAGCAGCTCACCGCCCACAGTGGGCGTCGCTGCCAGCAGCATCATCCACAGTCCCCAGTCGATGGGTGCGATGGGTGCGATGGCTGCCATGGCTGCCACGCCCATGTCCTGCGAGTCGGACAAGAACGAGTACAGGAAGTTCAAGGTGAAGATGCCGCTGAAGTACGAGTTCAAGAACAAGAGCTGCGTCAAGCAGGAGCCCATCCACAAGGACGTGGACGAGCAGATGTCGCATACGCTGCCCCATGGCgtcgacgaggaggaggagctgcaccACCACGCCCATCTGCACCTGCACGCGAATGTGGCACACTCGGAGGACTCGGCCTGCCcgcccagcaccaccacccatCTGGGGGATGAGCATTTGATGCActtggagagggagagggagagggaaaggGAGCGCGAGAGGGAACGGGatcgggagcgggagcggaaCGACAGAGAACAATCAGCAACCAACCAGCAGCCCGCCTCCTCAACGGTGATTGTCCTGGAGCACAACTCGGACGGCCAGACCCGCACCATTGTGCCCCTGAGCAAGCCCTACTACGAGGCAGATCCACCAGGCGAGCGGTATGTGCGCTTCGGACAGCCCTCCTCCAGCATTCTGGAGACGATCCTGACCAGCCAGCACCGCCTGGAGGCGGCTGCCGCAGCGGCCAATGCCTGCCGGCAGGCGAACGCTGCCACCCCGCCACCCACGTCGCCCACTGAGATGGCCTACAGCTACAAGAAGTCGCAGCGATACGGCAACGCGGTGAGTCCGGACTCCAGCTCGAATCTGGGACAGCCGCAGGAGCAGCTGTCGGCCGCCGGAGTGGGCGCGGgcatgggcgtgggcgtggcggAGCAGGAGCTCGTCACGAGGGGCACCCTCATCAAGGGGGAGTgctcgccgccgccgccgtcgcacCATCACCACAACGTGATCTTCTCGCCCTCGCGACACGTCTCGTACATGGGTCAGGGCGAGGCGGGCGGCGGTCACGGCGGCCACTCGCCGAGTCCCAGCTATCCGGGGTATCCGCACCATTACGGGAGTGCGGCCACCTCCACCTTCCACTCGCCGCCACACAGCTCCCACTCGCCGTTCGACCGGCAGTCGAACGCGTCGAGCGGCGGCGGATCCGCCTCGAATCTGCATCTGCTGCAGAGCAGCACCCAGATGCTGAACCACCCGCTGATGCAGCCACTGACACCGCTGCAGCGTCTCTCGCCGCTGCGCATCTCCCCGCCCAGCAGCCTCAGTCCGGACGGCAACTCGTGTCCGCGCAGCGGCTCCCCCCTGAGTCCCAATTCGCTGGCCTCGCGCGGCTACCGCTCGCTGCCGTATCCGCTGAAGAAGAAGGACGGCAAGATGCACTACGAGTGCAACGTGTGCTGCAAGACCTTCGGCCAGCTGAGCAACCTGAAGGTGCATCTGCGCACCCACTCGGGCGAGCGGCCGTTCAAGTGCAACGTCTGCACGAAGAGCTTCACCCAGCTGGCGCACCTGCAGAAGCATCATCTGGTGCACACGGGCGAGAAGCCGCACCAGTGCGACATCTGCAAGAAGCGCTTCTCGAGCACGTCCAACCTGAAGACACATCTGCGGCTGCACAGCGGCCAGAAGCCCTACGCCTGCGATCTCTGTCCGCAGAAGTTCACgcaatttgtgcatttgaAGCTGCACAAGCGGCTGCACACCAACGATCGGCCGTACGTGTGCCAGGGCTGTGACAAGAAGTACATCAGTGCCTCGGGGCTGCGCACCCACTGGAAGACGACCAGCTGCAAGCCCAACAAtctggaggaggagctggccATGGCAGCGGCGGCCACATCCGAGTGCTTAGACAAGGATCATCCCGAGCCGGATAGCCGTGAGGCCtacgagcagctgcagcagcatatGGTGCATCCCAGTCTGAGGCACTCGCCGCCGCGTCTTATTCCGTTGGGCAGTCACATGCAGGCAGCCggacagcatcagcagcagcagccaccaccgccgccgcacATGATGCTGGGTCCAGCCCCAATGCTGTTGaccacagccagccagctgccaccaccgccgccccatcatctgcagcagcagcagcagggatcCCCCAACCAACGTCCCACGCCCCCACACCTGCAtcagcatccgcatccgcactcgcatccacatccgcatcagcagcagcagcagcagcagcaacactcgCCGCAGGGCGGCAGCCTGAAAGTATTGAAGCCGCTGCCCGACAACGGAGGAGGAGCCTACATGCATGCGCCCCATGTGCAGGCCCAGGAGAACCGCCCCTCGGTCATAGAGTCCTCCAATCAGCCCATGATCATTGAGTGCACGTAA
Protein Sequence: MHGHHHNHQQQQQQQQQQQQQQGQQQQQHQQTAAGTANNMKAASHHHHHHHPHVQTHPHPHPHPHHKLSTRRTARSRSRSRSRSPTPDGNQDYDVTRMREEDFERLAVYLVPDVQAERGLSNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHISYGIIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHLENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQASGEEDLEEEAEEAEEELEDQNQDQDHDGMPPHKKPHYSMPAPEIPAEVAVSHITYVMGLHLPATPGGAPTQGAGSTQEALPPAPPPTGSGAGAGAGSGSCCRRASPPAHVSTTSCGGAHHPHIIQHGRHASVIIGQDRSPLASSSDKDTAGSPLSGLDHQLTPQDGSVRSVRSDEGYHSNECHEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPQSSSSPPTVGVAASSIIHSPQSMGAMGAMAAMAATPMSCESDKNEYRKFKVKMPLKYEFKNKSCVKQEPIHKDVDEQMSHTLPHGVDEEEELHHHAHLHLHANVAHSEDSACPPSTTTHLGDEHLMHLERERERERERERERDRERERNDREQSATNQQPASSTVIVLEHNSDGQTRTIVPLSKPYYEADPPGERYVRFGQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQPQEQLSAAGVGAGMGVGVAEQELVTRGTLIKGECSPPPPSHHHHNVIFSPSRHVSYMGQGEAGGGHGGHSPSPSYPGYPHHYGSAATSTFHSPPHSSHSPFDRQSNASSGGGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDHPEPDSREAYEQLQQHMVHPSLRHSPPRLIPLGSHMQAAGQHQQQQPPPPPHMMLGPAPMLLTTASQLPPPPPHHLQQQQQGSPNQRPTPPHLHQHPHPHSHPHPHQQQQQQQQHSPQGGSLKVLKPLPDNGGGAYMHAPHVQAQENRPSVIESSNQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00601290;
90% Identity: iTF_00611586;
80% Identity: -