Basic Information

Insect: Drosophila obscura
Gene Symbol: -
Assembly: GCA_018151105.1
Location: NW:291396-293880[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1.5e-05 0.00095 19.2 2.9 3 23 335 355 334 355 0.98

2 5 9.6e-08 5.9e-06 26.1 0.1 1 23 361 383 361 383 0.98

3 5 0.0093 0.57 10.5 1.3 3 23 391 411 389 411 0.97

4 5 2.8e-05 0.0017 18.4 1.9 1 23 417 439 417 439 0.99

5 5 1.2e-05 0.00072 19.6 1.0 1 23 445 467 445 467 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1.5e-05	0.00095	19.2	2.9	3	23	335	355	334	355	0.98
2	5	9.6e-08	5.9e-06	26.1	0.1	1	23	361	383	361	383	0.98
3	5	0.0093	0.57	10.5	1.3	3	23	391	411	389	411	0.97
4	5	2.8e-05	0.0017	18.4	1.9	1	23	417	439	417	439	0.99
5	5	1.2e-05	0.00072	19.6	1.0	1	23	445	467	445	467	0.96

Sequence Information

Coding Sequence: ATGGCGAACAACCTGGAGTCACGTGTGGTGGATCTGGACGTGGCCTGCCTGATCTGCCTGAATGAGGAGTCCGGCCATATCTCCATTTACAGCCATGACTTGGAGCCGCCGCACACCCTGATTGCGGACATGATCCGCTGTTGCACCAGCCTGCAACTGGAGAGTTTGCAAATGCAGCGCTGGCCGGACAAGATCTGCGAGCAGTGCCACAGTGAACTAGCAGTCGCCTACCGCTTCTATGAGAAGTGCCTGCTGATCGAAAAGCTATTCCTCACTGCGACCAACAGCGCTCTTCTCGTCGACGTCGACGAATTGGCCAAGAACCAGCAGCTGAAACTGGATTTGGAACAGCATCACGTCAAGCTGCCATCCAGCTTAAAAATCAAACGCGTCGAAGTGGATGCAGACATTCCTCTTGCAAGTCGGACGGTGGTGTGTTCAGTGTCAGCAGCGCCCAGGGCAATCACAGTACAAACCACTGGGTCTGGCTCAATATTACCTACATCTGCAGCGACCACAACAGCAGCTCCGATTCTTCCCGTCACCAAATTTGAGTACTTTCAGGAGGACGGGGAGGACACAGACTCACTGGGCCTGTTGCCAGATACCGCCGATTCACTGGTCATGTCGCTGGACACCCTCATAGAGACGGTGCCCATTAAGGAGCAGCCAGAAGACGAAATGTCGTCGGATGAGGAGGATAAAAAGAGGACCGTCCCACAAACCTGGGACGAGAATCCCCCGAGCCCAGAGCATGCCTATGAAATCGAAACGATACTAACTAAGAAAACTCAGGGGGGGCCACAGACTGAGCTGCCCCAACCGCCGCGGACTTCATCACGGGCCCTCAACACGATTCAACGATGCAATATAAGCAAACGCACTTACAAACGCGTCACACCGATCTTTAAGAGGGAGGTTGACGACGGCTACGTGCTGTTCGATAGCCAACAGATAGGCATTCCTGAGACACGTCGCCACGCGGAGCGTGCGCGCAAAATTTGTCATGTGTGCGGGAACACCTACAAGTATCAGCATGCCCTCAACGCACACATGCGGCGGCATAACAACGATCGTCCCTATCCGTGTGAAGTCTGCCAGAAGGCCTTCATATCGAACGTGGAGCTGCGCCGGCATATGCGTGTCCACACCGGGCAGAAGCCCTATGGGTGTCGCTATTGTGACCGCCGCTTCTCGGActttggcagcagcaaaaagcaTGAACGCATCCACACCGGTGAGCGTCCGTATGTGTGCGAGGTGTGCCACAAGGGCTTTGCCTACGCCCACGTGCTGACCGTGCACCGGCGTACACACACCGGAAAGAAGCAGTTCCAGTGCACGCAGTGCGACAAGGGATTCACCAAGAAGAACTACTTGGCCGCCCACCTGGATCAGCACAACGGCGTCACTACGTCCGCGCCAGCGGCCAAGCGTCCGGCCGCACGCAAGCTCCAAAAGAGGCATGTCCCGGAGGCACTGTTCATCGGTCAGTTAATGCTTGGTACCGAGCCGCCCAAGGTGCTGGAGGAATGCATTGTCACCCACGATTTCATGTTCAACGAAGAGGACGAGGCCGATGCCGACGATCATGATCTGGAGGCGGCCGGGGAGAAACGGGAAATGGAGCTGGACGATCCAGAGCCGGAGCACGATGACTTCGACGATGTTGATGTCTATCACCACAGTGTGCGCTCCGTCAAGGATGACCCTTATGCGCTTGTCGGGGATCTGCTGGACTCCGAGGAGTTCGCAGACGATTCCAAATATCTGATTGACTAG
Protein Sequence: MANNLESRVVDLDVACLICLNEESGHISIYSHDLEPPHTLIADMIRCCTSLQLESLQMQRWPDKICEQCHSELAVAYRFYEKCLLIEKLFLTATNSALLVDVDELAKNQQLKLDLEQHHVKLPSSLKIKRVEVDADIPLASRTVVCSVSAAPRAITVQTTGSGSILPTSAATTTAAPILPVTKFEYFQEDGEDTDSLGLLPDTADSLVMSLDTLIETVPIKEQPEDEMSSDEEDKKRTVPQTWDENPPSPEHAYEIETILTKKTQGGPQTELPQPPRTSSRALNTIQRCNISKRTYKRVTPIFKREVDDGYVLFDSQQIGIPETRRHAERARKICHVCGNTYKYQHALNAHMRRHNNDRPYPCEVCQKAFISNVELRRHMRVHTGQKPYGCRYCDRRFSDFGSSKKHERIHTGERPYVCEVCHKGFAYAHVLTVHRRTHTGKKQFQCTQCDKGFTKKNYLAAHLDQHNGVTTSAPAAKRPAARKLQKRHVPEALFIGQLMLGTEPPKVLEECIVTHDFMFNEEDEADADDHDLEAAGEKREMELDDPEPEHDDFDDVDVYHHSVRSVKDDPYALVGDLLDSEEFADDSKYLID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603586;
90% Identity: iTF_00603586;
80% Identity: -